Pik3r5 (phosphoinositide-3-kinase, regulatory subunit 5) - Rat Genome Database

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Gene: Pik3r5 (phosphoinositide-3-kinase, regulatory subunit 5) Rattus norvegicus
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Symbol: Pik3r5
Name: phosphoinositide-3-kinase, regulatory subunit 5
RGD ID: 1563261
Description: Enables 1-phosphatidylinositol-3-kinase regulator activity. Involved in phosphatidylinositol metabolic process. Part of phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in ataxia with oculomotor apraxia type 3 and colon cancer. Orthologous to human PIK3R5 (phosphoinositide-3-kinase regulatory subunit 5); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; phosphatidylinositol 3-kinase class I signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC497931; phosphoinositide 3-kinase regulatory subunit 5; phosphoinositide-3-kinase, regulatory subunit 5, p101; RGD1563261; similar to novel protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81053,631,469 - 53,699,550 (+)NCBIGRCr8
mRatBN7.21053,132,585 - 53,200,663 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,132,603 - 53,199,374 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1057,838,940 - 57,859,341 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,327,976 - 57,348,381 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01052,836,777 - 52,857,177 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,013,686 - 55,078,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,013,703 - 55,080,421 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01054,757,809 - 54,822,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,227,872 - 55,248,301 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1052,347,081 - 52,367,505 (+)NCBICelera
Cytogenetic Map10q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pik3r5Ratcolon cancer  ISOPIK3R5 (Homo sapiens)13432047DNA:hypermethylationRGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pik3r5Ratataxia with oculomotor apraxia type 3  ISOPIK3R5 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:22065524 more ...
Pik3r5Ratspastic ataxia  ISOPIK3R5 (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic ataxiaClinVarPMID:25741868
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pik3r5Ratataxia with oculomotor apraxia type 3  ISOPIK3R5 (Homo sapiens)7240710 OMIM 

1 to 20 of 99 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pik3r5Rat1,2-dichloroethane decreases expressionISOPik3r5 (Mus musculus)6480464ethylene dichloride results in decreased expression of PIK3R5 mRNACTDPMID:28960355
Pik3r5Rat1,2-dimethylhydrazine increases expressionISOPik3r5 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of PIK3R5 mRNACTDPMID:22206623
Pik3r5Rat2,2',4,4'-Tetrabromodiphenyl ether multiple interactionsISOPik3r5 (Mus musculus)6480464[Flame Retardants results in increased abundance of 2 more ...CTDPMID:38995820
Pik3r5Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOPik3r5 (Mus musculus)6480464Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PIK3R5 gene]CTDPMID:20819909
Pik3r5Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of PIK3R5 mRNACTDPMID:33387578
Pik3r5Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of PIK3R5 mRNACTDPMID:34747641
Pik3r5Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPik3r5 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PIK3R5 mRNACTDPMID:28922406
Pik3r5Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOPik3r5 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of PIK3R5 mRNACTDPMID:20819909
Pik3r5Rat2,6-di-tert-butyl-4-methylphenol increases expressionISOPik3r5 (Mus musculus)6480464Butylated Hydroxytoluene results in increased expression of PIK3R5 mRNACTDPMID:19000923
Pik3r5Rat3,3',5,5'-tetrabromobisphenol A increases expressionISOPik3r5 (Mus musculus)6480464tetrabromobisphenol A results in increased expression of PIK3R5 mRNACTDPMID:25172293
Pik3r5Rat3-methylcholanthrene increases expressionISOPik3r5 (Mus musculus)6480464Methylcholanthrene results in increased expression of PIK3R5 mRNACTDPMID:20713471
Pik3r5Rat7,12-dimethyltetraphene increases expressionISOPik3r5 (Mus musculus)64804649 more ...CTDPMID:20025956
Pik3r5Ratacetamide increases expressionEXP 6480464acetamide results in increased expression of PIK3R5 mRNACTDPMID:31881176
Pik3r5Ratacrylamide increases expressionISOPik3r5 (Mus musculus)6480464Acrylamide results in increased expression of PIK3R5 proteinCTDPMID:20025956
Pik3r5Rataflatoxin B1 decreases methylationISOPIK3R5 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of PIK3R5 intronCTDPMID:30157460
Pik3r5RatAflatoxin B2 alpha increases methylationISOPIK3R5 (Homo sapiens)6480464aflatoxin B2 results in increased methylation of PIK3R5 intronCTDPMID:30157460
Pik3r5Ratall-trans-retinoic acid increases expressionISOPik3r5 (Mus musculus)6480464Tretinoin results in increased expression of PIK3R5 proteinCTDPMID:20025956
Pik3r5Ratall-trans-retinoic acid increases expressionISOPIK3R5 (Homo sapiens)6480464Tretinoin results in increased expression of PIK3R5 mRNACTDPMID:33167477
Pik3r5Ratalpha-Zearalanol increases expressionEXP 6480464Zeranol results in increased expression of PIK3R5 mRNACTDPMID:35163327
Pik3r5Ratanthracene-1,8,9-triol increases expressionISOPik3r5 (Mus musculus)6480464Anthralin results in increased expression of PIK3R5 proteinCTDPMID:20025956

1 to 20 of 99 rows

Cellular Component
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pik3r5Ratcentriolar satellite located_inIEAUniProtKB:Q8WYR1 and ensembl:ENSP000003928121600115GO_REF:0000107EnsemblGO_REF:0000107
Pik3r5Ratcentriolar satellite located_inISOPIK3R5 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Pik3r5Ratcentriolar satellite located_inIEAUniProtKB:L7RT34 and ensembl:ENSP000003928121600115GO_REF:0000107EnsemblGO_REF:0000107
Pik3r5Ratcytoplasm located_inISOPIK3R5 (Sus scrofa)1624291 PMID:12507995RGDPMID:12507995
Pik3r5Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Pik3r5Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Pik3r5Ratcytosol located_inISOPIK3R5 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Pik3r5Ratcytosol located_inIEAUniProtKB:L7RT34 and ensembl:ENSP000003928121600115GO_REF:0000107EnsemblGO_REF:0000107
Pik3r5Ratcytosol located_inIEAUniProtKB:Q8WYR1 and ensembl:ENSP000003928121600115GO_REF:0000107EnsemblGO_REF:0000107
Pik3r5Ratmembrane located_inISOPIK3R5 (Sus scrofa)1624291 PMID:12507995RGDPMID:12507995
Pik3r5Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Pik3r5Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Pik3r5Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Pik3r5Ratphosphatidylinositol 3-kinase complex  IDA 4144086 RGD 
Pik3r5Ratphosphatidylinositol 3-kinase complex part_ofIBAMGI:2144613 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Pik3r5Ratphosphatidylinositol 3-kinase complex, class IA part_ofISOPIK3R5 (Homo sapiens)1624291 PMID:10358071RGDPMID:10358071
Pik3r5Ratphosphatidylinositol 3-kinase complex, class IB part_ofIEAInterPro:IPR0195221600115GO_REF:0000002InterProGO_REF:0000002
Pik3r5Ratphosphatidylinositol 3-kinase complex, class IB part_ofISOPIK3R5 (Sus scrofa)1624291 PMID:12507995RGDPMID:12507995
Pik3r5Ratplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044
Pik3r5Ratplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
1 to 20 of 20 rows

Molecular Function

  

Imported Annotations - KEGG (archival)

1 to 20 of 34 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pik3r5Ratacute myeloid leukemia pathway  IEA 6907045 KEGGrno:05221
Pik3r5Rataldosterone signaling pathway   IEA 6907045 KEGGrno:04960
Pik3r5Ratapoptotic cell death pathway  IEA 6907045 KEGGrno:04210
Pik3r5RatB cell receptor signaling pathway  IEA 6907045 KEGGrno:04662
Pik3r5Ratceramide signaling pathway  IEA 6907045 KEGGrno:05212
Pik3r5RatChagas disease pathway  IEA 6907045 KEGGrno:05142
Pik3r5Ratchemokine mediated signaling pathway  IEA 6907045 KEGGrno:04062
Pik3r5Ratchronic myeloid leukemia pathway  IEA 6907045 KEGGrno:05220
Pik3r5Ratcolorectal cancer pathway   IEA 6907045 KEGGrno:05210
Pik3r5Ratendometrial cancer pathway   IEA 6907045 KEGGrno:05213
Pik3r5RatEntamoebiasis pathway  IEA 6907045 KEGGrno:05146
Pik3r5Ratepidermal growth factor/neuregulin signaling pathway   IEA 6907045 KEGGrno:04012
Pik3r5RatFc epsilon receptor mediated signaling pathway  IEA 6907045 KEGGrno:04664
Pik3r5RatFc gamma receptor mediated signaling pathway  IEA 6907045 KEGGrno:04666
Pik3r5Ratglioma pathway  IEA 6907045 KEGGrno:05214
Pik3r5Rathepatitis C pathway  IEA 6907045 KEGGrno:05160
Pik3r5Ratinfluenza A pathway  IEA 6907045 KEGGrno:05164
Pik3r5Ratinsulin signaling pathway   IEA 6907045 KEGGrno:04910
Pik3r5RatJak-Stat signaling pathway   IEA 6907045 KEGGrno:04630
Pik3r5Ratmeasles pathway  IEA 6907045 KEGGrno:05162
1 to 20 of 34 rows

Imported Annotations - PID (archival)


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Platelet-derived growth factor-BB-mediated activation of Akt suppresses smooth muscle-specific gene expression through inhibition of mitogen-activated protein kinase and redistribution of serum response factor. Kaplan-Albuquerque N, etal., J Biol Chem. 2003 Oct 10;278(41):39830-8. Epub 2003 Jul 25.
3. Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation. Kondo Y, etal., Proc Natl Acad Sci U S A. 2004 May 11;101(19):7398-403. Epub 2004 May 3.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12507995   PMID:15611065  



Pik3r5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81053,631,469 - 53,699,550 (+)NCBIGRCr8
mRatBN7.21053,132,585 - 53,200,663 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,132,603 - 53,199,374 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1057,838,940 - 57,859,341 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,327,976 - 57,348,381 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01052,836,777 - 52,857,177 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,013,686 - 55,078,986 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,013,703 - 55,080,421 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01054,757,809 - 54,822,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,227,872 - 55,248,301 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1052,347,081 - 52,367,505 (+)NCBICelera
Cytogenetic Map10q24NCBI
PIK3R5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,878,916 - 8,965,707 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,878,911 - 8,965,712 (-)EnsemblGRCh38hg38GRCh38
GRCh37178,782,233 - 8,869,024 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,724,138 - 8,756,559 (-)NCBINCBI36Build 36hg18NCBI36
Build 34178,724,137 - 8,756,559NCBI
Celera178,814,067 - 8,900,857 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef178,681,483 - 8,768,185 (-)NCBIHuRef
CHM1_1178,791,349 - 8,878,194 (-)NCBICHM1_1
T2T-CHM13v2.0178,786,072 - 8,872,872 (-)NCBIT2T-CHM13v2.0
Pik3r5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,322,951 - 68,388,675 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,322,947 - 68,388,675 (+)EnsemblGRCm39 Ensembl
GRCm381168,432,125 - 68,497,849 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,432,121 - 68,497,849 (+)EnsemblGRCm38mm10GRCm38
MGSCv371168,245,627 - 68,311,348 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,248,320 - 68,314,041 (+)NCBIMGSCv36mm8
Celera1175,369,339 - 75,435,134 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1141.69NCBI
Pik3r5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,065,857 - 8,091,486 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,025,231 - 8,091,406 (+)NCBIChiLan1.0ChiLan1.0
PIK3R5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21964,780,309 - 64,868,388 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11769,590,055 - 69,677,728 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01742,686,483 - 42,773,668 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11747,421,204 - 47,507,282 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1747,475,201 - 47,507,282 (+)Ensemblpanpan1.1panPan2
PIK3R5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,538,354 - 33,604,984 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,532,708 - 33,604,984 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,674,664 - 33,741,285 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,641,537 - 33,708,256 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,635,875 - 33,708,207 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,609,183 - 33,675,765 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,566,733 - 33,633,509 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,743,236 - 33,809,805 (-)NCBIUU_Cfam_GSD_1.0
Pik3r5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560248,554,342 - 48,581,804 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365952,029,814 - 2,055,976 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365952,029,074 - 2,053,954 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3R5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,979,207 - 54,054,490 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,979,206 - 54,046,927 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21256,731,153 - 56,799,397 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3R5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1168,235,891 - 8,322,347 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl168,234,962 - 8,322,320 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605913,059,577 - 13,147,349 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pik3r5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478611,408,279 - 11,472,472 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Pik3r5
369 total Variants

Predicted Target Of
Summary Value
Count of predictions:246
Count of miRNA genes:165
Interacting mature miRNAs:183
Transcripts:ENSRNOT00000032785
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 72 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
61441Btemp1Thermal response to stress QTL 14body temperature trait (VT:0005535)core body temperature (CMO:0001036)103539245763642539Rat
1549846Scl47Serum cholesterol level QTL 473.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)105057470795574707Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
152025229Scl83Serum cholesterol level QTL 834.33blood cholesterol amount (VT:0000180)103571058068663659Rat
1578779Tcas10Tongue tumor susceptibility QTL 103.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)103129743976297439Rat
152025227Bw195Body weight QTL 1955.73body mass (VT:0001259)104698969968663659Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
1298069Bp168Blood pressure QTL 1685.5blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)102652195798003205Rat
2293669Bmd33Bone mineral density QTL 334.50.0001femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)104944455181709989Rat
152025224Bw193Body weight QTL 1936.47body mass (VT:0001259)105166340575085664Rat

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alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000032785   ⟹   ENSRNOP00000030578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1053,132,603 - 53,199,374 (+)Ensembl
Rnor_6.0 Ensembl1055,013,703 - 55,080,421 (+)Ensembl
RefSeq Acc Id: NM_001191923   ⟹   NP_001178852
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81053,677,832 - 53,698,261 (+)NCBI
mRatBN7.21053,178,944 - 53,199,374 (+)NCBI
Rnor_6.01055,058,434 - 55,078,863 (+)NCBI
Rnor_5.01054,757,809 - 54,822,968 (+)NCBI
Celera1052,347,081 - 52,367,505 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006246770   ⟹   XP_006246832
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81053,631,469 - 53,699,550 (+)NCBI
mRatBN7.21053,132,585 - 53,200,663 (+)NCBI
Rnor_6.01055,013,686 - 55,078,986 (+)NCBI
Rnor_5.01054,757,809 - 54,822,968 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597454   ⟹   XP_017452943
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81053,631,469 - 53,699,550 (+)NCBI
mRatBN7.21053,132,585 - 53,200,663 (+)NCBI
Rnor_6.01055,013,686 - 55,078,986 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039086573   ⟹   XP_038942501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81053,631,555 - 53,699,550 (+)NCBI
mRatBN7.21053,132,612 - 53,200,663 (+)NCBI
RefSeq Acc Id: XM_063269618   ⟹   XP_063125688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81053,670,884 - 53,699,550 (+)NCBI
RefSeq Acc Id: XM_063269619   ⟹   XP_063125689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81053,637,672 - 53,699,550 (+)NCBI
1 to 9 of 9 rows
Protein RefSeqs NP_001178852 (Get FASTA)   NCBI Sequence Viewer  
  XP_006246832 (Get FASTA)   NCBI Sequence Viewer  
  XP_017452943 (Get FASTA)   NCBI Sequence Viewer  
  XP_038942501 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125688 (Get FASTA)   NCBI Sequence Viewer  
  XP_063125689 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM04809 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000030578
  ENSRNOP00000030578.3
1 to 9 of 9 rows
RefSeq Acc Id: NP_001178852   ⟸   NM_001191923
- UniProtKB: D4A4I3 (UniProtKB/TrEMBL),   A6HFK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246832   ⟸   XM_006246770
- Peptide Label: isoform X1
- UniProtKB: D4A4I3 (UniProtKB/TrEMBL),   A6HFK4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452943   ⟸   XM_017597454
- Peptide Label: isoform X2
- UniProtKB: A6HFK4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000030578   ⟸   ENSRNOT00000032785
RefSeq Acc Id: XP_038942501   ⟸   XM_039086573
- Peptide Label: isoform X1
- UniProtKB: D4A4I3 (UniProtKB/TrEMBL),   A6HFK4 (UniProtKB/TrEMBL)

Name Modeler Protein Id AA Range Protein Structure
AF-D4A4I3-F1-model_v2 AlphaFold D4A4I3 1-872 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13697297
Promoter ID:EPDNEW_R7820
Type:multiple initiation site
Name:Pik3r5_1
Description:phosphoinositide-3-kinase, regulatory subunit 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01055,013,702 - 55,013,762EPDNEW


1 to 16 of 16 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-24635 BioCyc
BioCyc Pathway PWY-6352 [3-phosphoinositide biosynthesis] BioCyc
BioCyc Pathway Image PWY-6352 BioCyc
Ensembl Genes ENSRNOG00000023428 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000032785 ENTREZGENE
  ENSRNOT00000032785.6 UniProtKB/TrEMBL
InterPro PI3K_1B_gamma_p101_su UniProtKB/TrEMBL
KEGG Report rno:497931 UniProtKB/TrEMBL
NCBI Gene 497931 ENTREZGENE
PANTHER PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 5 UniProtKB/TrEMBL
  PTHR15593 UniProtKB/TrEMBL
Pfam PI3K_1B_p101 UniProtKB/TrEMBL
PhenoGen Pik3r5 PhenoGen
RatGTEx ENSRNOG00000023428 RatGTEx
UniProt A6HFK4 ENTREZGENE, UniProtKB/TrEMBL
  D4A4I3 ENTREZGENE, UniProtKB/TrEMBL
1 to 16 of 16 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-09 Pik3r5  phosphoinositide-3-kinase, regulatory subunit 5  Pik3r5  phosphoinositide-3-kinase, regulatory subunit 5, p101  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Pik3r5  phosphoinositide-3-kinase, regulatory subunit 5, p101  RGD1563261_predicted  similar to novel protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563261_predicted  similar to novel protein (predicted)  LOC497931  similar to novel protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC497931  similar to novel protein      Symbol and Name status set to provisional 70820 PROVISIONAL