Usp10 (ubiquitin specific peptidase 10) - Rat Genome Database

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Gene: Usp10 (ubiquitin specific peptidase 10) Rattus norvegicus
Analyze
Symbol: Usp10
Name: ubiquitin specific peptidase 10
RGD ID: 1561965
Description: Predicted to enable several functions, including cysteine-type peptidase activity; p53 binding activity; and transmembrane transporter binding activity. Predicted to be involved in several processes, including monoubiquitinated protein deubiquitination; negative regulation of canonical NF-kappaB signal transduction; and negative regulation of stress granule assembly. Predicted to be located in cytoplasm; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosolic ribosome; early endosome; and nucleus. Orthologous to human USP10 (ubiquitin specific peptidase 10); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: deubiquitinating enzyme 10; MGC124997; ubiquitin carboxyl-terminal hydrolase 10; ubiquitin specific protease 10; ubiquitin thioesterase 10; ubiquitin thiolesterase 10; ubiquitin-specific-processing protease 10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,881,255 - 64,923,522 (+)NCBIGRCr8
mRatBN7.21947,972,858 - 48,014,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,972,611 - 48,014,897 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1954,767,502 - 54,809,229 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01955,448,244 - 55,489,969 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,661,267 - 57,703,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,566,274 - 52,608,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,566,607 - 52,608,817 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01963,313,910 - 63,356,424 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41950,202,951 - 50,244,677 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1947,229,671 - 47,271,396 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO,ISS)
cytosol  (IBA,IEA,ISO)
cytosolic ribosome  (IEA,ISO)
early endosome  (IBA,IEA,ISO,ISS)
intermediate filament cytoskeleton  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA,ISO,ISS)
protein-containing complex  (IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit(+) cardiac progenitor cells by promoting miR-675. Cai B, etal., J Pineal Res. 2016 Aug;61(1):82-95. doi: 10.1111/jpi.12331. Epub 2016 Apr 29.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:19398555   PMID:20096447   PMID:21962518   PMID:22658674   PMID:22681889   PMID:24845384   PMID:25861989   PMID:35987808  


Genomics

Comparative Map Data
Usp10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,881,255 - 64,923,522 (+)NCBIGRCr8
mRatBN7.21947,972,858 - 48,014,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,972,611 - 48,014,897 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1954,767,502 - 54,809,229 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01955,448,244 - 55,489,969 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,661,267 - 57,703,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,566,274 - 52,608,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,566,607 - 52,608,817 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01963,313,910 - 63,356,424 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41950,202,951 - 50,244,677 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1947,229,671 - 47,271,396 (+)NCBICelera
Cytogenetic Map19q12NCBI
USP10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381684,700,000 - 84,779,922 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1684,699,986 - 84,779,922 (+)EnsemblGRCh38hg38GRCh38
GRCh371684,733,606 - 84,813,528 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361683,291,056 - 83,371,029 (+)NCBINCBI36Build 36hg18NCBI36
Build 341683,291,084 - 83,370,670NCBI
Celera1669,035,743 - 69,115,795 (+)NCBICelera
Cytogenetic Map16q24.1NCBI
HuRef1670,486,450 - 70,566,405 (+)NCBIHuRef
CHM1_11686,145,099 - 86,225,097 (+)NCBICHM1_1
T2T-CHM13v2.01690,766,262 - 90,846,179 (+)NCBIT2T-CHM13v2.0
Usp10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,637,099 - 120,684,299 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8120,637,099 - 120,684,299 (+)EnsemblGRCm39 Ensembl
GRCm388119,910,360 - 119,957,560 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8119,910,360 - 119,957,560 (+)EnsemblGRCm38mm10GRCm38
MGSCv378122,434,752 - 122,481,457 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368122,796,829 - 122,843,534 (+)NCBIMGSCv36mm8
Celera8124,131,245 - 124,177,988 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map868.61NCBI
Usp10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955541242,091 - 296,059 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955541242,182 - 296,018 (+)NCBIChiLan1.0ChiLan1.0
USP10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21894,449,698 - 94,529,802 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116100,366,823 - 100,446,915 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01665,367,463 - 65,447,549 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11684,719,540 - 84,787,714 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1684,712,913 - 84,787,714 (+)Ensemblpanpan1.1panPan2
USP10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1567,736,215 - 67,774,756 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl567,736,730 - 67,809,206 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha567,750,854 - 67,823,397 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0567,968,955 - 68,042,190 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl567,968,955 - 68,042,589 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1567,984,393 - 68,056,880 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0567,819,079 - 67,892,003 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0568,234,061 - 68,306,639 (-)NCBIUU_Cfam_GSD_1.0
Usp10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934927,554,574 - 27,618,345 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366413,307,931 - 3,350,517 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366413,308,121 - 3,350,476 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl63,977,231 - 4,043,533 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.163,977,235 - 4,043,539 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.264,473,366 - 4,491,966 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1570,105,653 - 70,186,512 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl570,139,470 - 70,185,884 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660475,563,590 - 5,644,539 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247461,554,023 - 1,617,308 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247461,553,891 - 1,616,711 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Usp10
127 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:60
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000022432
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193383821455283146Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat

Markers in Region
BI288552  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21948,002,896 - 48,003,067 (+)MAPPERmRatBN7.2
Rnor_6.01952,596,492 - 52,596,662NCBIRnor6.0
Rnor_5.01963,344,096 - 63,344,266UniSTSRnor5.0
RGSC_v3.41950,232,674 - 50,232,844UniSTSRGSC3.4
Celera1947,259,393 - 47,259,563UniSTS
RH 3.4 Map19647.2UniSTS
Cytogenetic Map19q12UniSTS
RH129100  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21947,999,157 - 47,999,339 (+)MAPPERmRatBN7.2
Rnor_6.01952,592,753 - 52,592,934NCBIRnor6.0
Rnor_5.01963,340,357 - 63,340,538UniSTSRnor5.0
RGSC_v3.41950,228,935 - 50,229,116UniSTSRGSC3.4
Celera1947,255,654 - 47,255,835UniSTS
RH 3.4 Map19635.1UniSTS
Cytogenetic Map19q12UniSTS
RH130276  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2182,128,850 - 2,129,056 (-)MAPPERmRatBN7.2
mRatBN7.21948,014,655 - 48,014,871 (+)MAPPERmRatBN7.2
Rnor_6.01952,608,576 - 52,608,791NCBIRnor6.0
Rnor_5.01963,356,180 - 63,356,395UniSTSRnor5.0
RGSC_v3.41950,244,433 - 50,244,648UniSTSRGSC3.4
Celera1947,271,152 - 47,271,367UniSTS
RH 3.4 Map19657.2UniSTS
Cytogenetic Map19q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 36 56 40 19 40 8 11 74 35 39 11 8
Low 7 1 1 1 2
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000022432   ⟹   ENSRNOP00000022432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1947,990,018 - 48,014,897 (+)Ensembl
Rnor_6.0 Ensembl1952,566,607 - 52,608,817 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000113547   ⟹   ENSRNOP00000079829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1947,972,611 - 48,014,897 (+)Ensembl
RefSeq Acc Id: NM_001034146   ⟹   NP_001029318
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,881,797 - 64,923,522 (+)NCBI
mRatBN7.21947,973,174 - 48,014,900 (+)NCBI
Rnor_6.01952,566,607 - 52,608,820 (+)NCBI
Rnor_5.01963,313,910 - 63,356,424 (+)NCBI
RGSC_v3.41950,202,951 - 50,244,677 (+)RGD
Celera1947,229,671 - 47,271,396 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772609   ⟹   XP_008770831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,881,255 - 64,923,522 (+)NCBI
mRatBN7.21947,972,858 - 48,014,900 (+)NCBI
Rnor_6.01952,566,274 - 52,608,064 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001029318 (Get FASTA)   NCBI Sequence Viewer  
  XP_008770831 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI05893 (Get FASTA)   NCBI Sequence Viewer  
  EDL92690 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022432
  ENSRNOP00000022432.5
  ENSRNOP00000079829
  ENSRNOP00000079829.1
GenBank Protein Q3KR59 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001029318   ⟸   NM_001034146
- UniProtKB: Q3KR59 (UniProtKB/Swiss-Prot),   A6IZL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770831   ⟸   XM_008772609
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZPC2 (UniProtKB/TrEMBL),   A6IZL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000022432   ⟸   ENSRNOT00000022432
RefSeq Acc Id: ENSRNOP00000079829   ⟸   ENSRNOT00000113547
Protein Domains
USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3KR59-F1-model_v2 AlphaFold Q3KR59 1-794 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701188
Promoter ID:EPDNEW_R11709
Type:initiation region
Name:Usp10_1
Description:ubiquitin specific peptidase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01952,566,603 - 52,566,663EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561965 AgrOrtholog
BioCyc Gene G2FUF-5497 BioCyc
Ensembl Genes ENSRNOG00000016509 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022432 ENTREZGENE
  ENSRNOT00000022432.6 UniProtKB/TrEMBL
  ENSRNOT00000113547.1 UniProtKB/TrEMBL
Gene3D-CATH Cysteine proteinases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7367339 IMAGE-MGC_LOAD
InterPro Ataxin-2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:307905 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124997 IMAGE-MGC_LOAD
NCBI Gene 307905 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PAM2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Usp10 PhenoGen
PROSITE USP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016509 RatGTEx
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZPC2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QBF0_RAT UniProtKB/TrEMBL
  A6IZL2 ENTREZGENE, UniProtKB/TrEMBL
  Q3KR59 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Usp10  ubiquitin specific peptidase 10  Usp10  ubiquitin specific protease 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Usp10  ubiquitin specific protease 10      Symbol and Name status set to provisional 70820 PROVISIONAL