Usp10 (ubiquitin specific peptidase 10) - Rat Genome Database

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Gene: Usp10 (ubiquitin specific peptidase 10) Rattus norvegicus
Analyze
Symbol: Usp10
Name: ubiquitin specific peptidase 10
RGD ID: 1561965
Description: Predicted to enable several functions, including cysteine-type peptidase activity; p53 binding activity; and transmembrane transporter binding activity. Predicted to be involved in several processes, including DNA damage response, signal transduction by p53 class mediator; monoubiquitinated protein deubiquitination; and negative regulation of canonical NF-kappaB signal transduction. Predicted to be located in cytoplasm; intermediate filament cytoskeleton; and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosolic ribosome; early endosome; and nucleus. Orthologous to human USP10 (ubiquitin specific peptidase 10); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: deubiquitinating enzyme 10; MGC124997; ubiquitin carboxyl-terminal hydrolase 10; ubiquitin specific protease 10; ubiquitin thioesterase 10; ubiquitin thiolesterase 10; ubiquitin-specific-processing protease 10
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,881,255 - 64,923,522 (+)NCBIGRCr8
mRatBN7.21947,972,858 - 48,014,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,972,611 - 48,014,897 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1954,767,502 - 54,809,229 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01955,448,244 - 55,489,969 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,661,267 - 57,703,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,566,274 - 52,608,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,566,607 - 52,608,817 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01963,313,910 - 63,356,424 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41950,202,951 - 50,244,677 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1947,229,671 - 47,271,396 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
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Reference
Notes
Source
Original Reference(s)
Usp10Ratpersistent fetal circulation syndrome  ISOUSP10 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital alveolar capillary dysplasiaClinVar 
Usp10Ratschizophrenia  ISOUSP10 (Homo sapiens)8554872ClinVar Annotator: match by term: SchizophreniaClinVarPMID:21681106 and PMID:30208311

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Object Symbol
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Original Reference(s)
Usp10Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of USP10 mRNA]CTDPMID:31150632
Usp10Rat1,2-dimethylhydrazine multiple interactionsISOUsp10 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of USP10 mRNACTDPMID:22206623
Usp10Rat17alpha-ethynylestradiol affects expressionISOUsp10 (Mus musculus)6480464Ethinyl Estradiol affects the expression of USP10 mRNACTDPMID:17555576
Usp10Rat17beta-estradiol increases expressionISOUsp10 (Mus musculus)6480464Estradiol results in increased expression of USP10 mRNACTDPMID:39298647
Usp10Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOUSP10 (Homo sapiens)64804642 more ...CTDPMID:31675489
Usp10Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUSP10 (Homo sapiens)6480464Tetrachlorodibenzodioxin affects the expression of USP10 mRNACTDPMID:22574217
Usp10Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUsp10 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of USP10 mRNACTDPMID:21570461 and PMID:24680724
Usp10Rat2,4,6-tribromophenol decreases expressionISOUSP10 (Homo sapiens)64804642 more ...CTDPMID:31675489
Usp10Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of USP10 mRNACTDPMID:21346803
Usp10Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of USP10 mRNACTDPMID:21346803
Usp10Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISOUSP10 (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of USP10 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of USP10 mRNACTDPMID:28628672
Usp10Rat4,4'-sulfonyldiphenol multiple interactionsISOUSP10 (Homo sapiens)6480464[bisphenol S co-treated with Fulvestrant] results in increased methylation of USP10 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in decreased expression of USP10 mRNACTDPMID:28628672 and PMID:31601247
Usp10Rat4-amino-2,6-dinitrotoluene affects expressionEXP 64804644-amino-2 and 6-dinitrotoluene affects the expression of USP10 mRNACTDPMID:21346803
Usp10Rataflatoxin B1 decreases methylationISOUSP10 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of USP10 intronCTDPMID:30157460
Usp10Ratall-trans-retinoic acid decreases expressionISOUSP10 (Homo sapiens)6480464Tretinoin results in decreased expression of USP10 mRNACTDPMID:33167477
Usp10Rataristolochic acid A decreases expressionISOUSP10 (Homo sapiens)6480464aristolochic acid I results in decreased expression of USP10 mRNACTDPMID:33212167
Usp10Ratarsane multiple interactionsISOUSP10 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of USP10 proteinCTDPMID:32802178
Usp10Ratarsenic atom multiple interactionsISOUSP10 (Homo sapiens)6480464[[sodium arsenite results in increased abundance of Arsenic] which co-treated with Benzo(a)pyrene] results in increased expression of USP10 proteinCTDPMID:32802178
Usp10Ratbenzatropine multiple interactionsISOUSP10 (Homo sapiens)6480464[Cuprizone co-treated with Benztropine] results in increased expression of USP10 proteinCTDPMID:34122009
Usp10Ratbenzo[a]pyrene increases expressionISOUsp10 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of USP10 mRNACTDPMID:22228805

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Biological Process
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Original Reference(s)
Usp10Ratautophagy involved_inIEAUniProtKB-KW:KW-00721600115GO_REF:0000043UniProtGO_REF:0000043
Usp10Ratcellular response to interleukin-1 involved_inISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
Usp10Ratcellular response to interleukin-1 involved_inISOUSP10 (Homo sapiens)1624291 PMID:25861989RGDPMID:25861989
Usp10Ratcellular response to interleukin-1 involved_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10RatDNA damage response involved_inISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
Usp10RatDNA damage response involved_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10RatDNA damage response involved_inIEAUniProtKB-KW:KW-02271600115GO_REF:0000043UniProtGO_REF:0000043
Usp10RatDNA damage response involved_inISOUSP10 (Homo sapiens)1624291 PMID:25861989RGDPMID:25861989
Usp10RatDNA damage response, signal transduction by p53 class mediator involved_inISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
Usp10RatDNA damage response, signal transduction by p53 class mediator involved_inIBAPANTHER:PTN002551655 and UniProtKB:Q146941600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp10RatDNA damage response, signal transduction by p53 class mediator involved_inISOUSP10 (Homo sapiens)1624291 PMID:20096447RGDPMID:20096447
Usp10RatDNA damage response, signal transduction by p53 class mediator involved_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10RatDNA repair involved_inIEAUniProtKB-KW:KW-02341600115GO_REF:0000043UniProtGO_REF:0000043
Usp10Ratmonoubiquitinated protein deubiquitination involved_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratmonoubiquitinated protein deubiquitination involved_inISOUSP10 (Homo sapiens)1624291 PMID:34348161 and PMID:34469731RGDPMID:34348161 and PMID:34469731
Usp10Ratnegative regulation of canonical NF-kappaB signal transduction involved_inISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
Usp10Ratnegative regulation of canonical NF-kappaB signal transduction involved_inISOUSP10 (Homo sapiens)1624291 PMID:25861989RGDPMID:25861989
Usp10Ratnegative regulation of canonical NF-kappaB signal transduction involved_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratnegative regulation of stress granule assembly involved_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratnegative regulation of stress granule assembly involved_inISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
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Cellular Component
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Original Reference(s)
Usp10Ratcytoplasm located_inISOUSP10 (Homo sapiens)1624291 PMID:20096447RGDPMID:20096447
Usp10Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Usp10Ratcytoplasm located_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Usp10Ratcytoplasm located_inISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
Usp10Ratcytosol located_inISOUSP10 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Usp10Ratcytosol located_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratcytosol is_active_inIBAFB:FBgn0016756 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp10Ratcytosolic ribosome is_active_inISOUSP10 (Homo sapiens)1624291 PMID:34348161 and PMID:34469731RGDPMID:34348161 and PMID:34469731
Usp10Ratcytosolic ribosome is_active_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratearly endosome located_inISOUSP10 (Homo sapiens)1624291 PMID:19398555RGDPMID:19398555
Usp10Ratearly endosome located_inIEAUniProtKB-SubCell:SL-00941600115GO_REF:0000044UniProtGO_REF:0000044
Usp10Ratearly endosome is_active_inIBAPANTHER:PTN000608145 and UniProtKB:Q146941600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp10Ratearly endosome located_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratearly endosome located_inISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
Usp10Ratendosome located_inIEAUniProtKB-KW:KW-09671600115GO_REF:0000043UniProtGO_REF:0000043
Usp10Ratintermediate filament cytoskeleton located_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratintermediate filament cytoskeleton located_inISOUSP10 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Usp10Ratnucleoplasm located_inIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratnucleoplasm located_inISOUSP10 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
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Molecular Function
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Original Reference(s)
Usp10Ratcysteine-type deubiquitinase activity enablesISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
Usp10Ratcysteine-type deubiquitinase activity enablesIEAEC:3.4.19.121600115GO_REF:0000003UniProtGO_REF:0000003
Usp10Ratcysteine-type deubiquitinase activity enablesIEAInterPro:IPR001394 and InterPro:IPR0182001600115GO_REF:0000002InterProGO_REF:0000002
Usp10Ratcysteine-type deubiquitinase activity enablesISOUSP10 (Homo sapiens)1624291 PMID:19398555 more ...RGDPMID:19398555 more ...
Usp10Ratcysteine-type deubiquitinase activity enablesIBAFB:FBgn0005632 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp10Ratcysteine-type deubiquitinase activity enablesIEAUniRule:UR0008807561600115GO_REF:0000104UniProtGO_REF:0000104
Usp10Ratcysteine-type deubiquitinase activity enablesIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratcysteine-type endopeptidase activity enablesISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
Usp10Ratcysteine-type endopeptidase activity enablesISOUSP10 (Homo sapiens)1624291 PMID:21962518RGDPMID:21962518
Usp10Ratcysteine-type endopeptidase activity enablesIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratcysteine-type peptidase activity enablesIEAUniProtKB-KW:KW-07881600115GO_REF:0000043UniProtGO_REF:0000043
Usp10Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Usp10Ratmolecular function inhibitor activity enablesIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratmolecular function inhibitor activity enablesISOUSP10 (Homo sapiens)1624291 PMID:27022092 and PMID:32302570RGDPMID:27022092 and PMID:32302570
Usp10Ratp53 binding enablesISSUniProtKB:Q146941600115GO_REF:0000024UniProtGO_REF:0000024
Usp10Ratp53 binding enablesISOUSP10 (Homo sapiens)1624291UniProtKB:P04637 and PMID:20096447RGDPMID:20096447
Usp10Ratp53 binding enablesIEAUniProtKB:Q14694 and ensembl:ENSP000002194731600115GO_REF:0000107EnsemblGO_REF:0000107
Usp10Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Usp10Ratprotein binding enablesISOUsp10 (Mus musculus)1624291UniProtKB:P10637 and PMID:35987808RGDPMID:35987808
Usp10Ratprotein binding enablesISOUSP10 (Homo sapiens)1624291UniProtKB:P13569 more ...RGDPMID:19398555 more ...
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#
Reference Title
Reference Citation
1. Long noncoding RNA H19 mediates melatonin inhibition of premature senescence of c-kit(+) cardiac progenitor cells by promoting miR-675. Cai B, etal., J Pineal Res. 2016 Aug;61(1):82-95. doi: 10.1111/jpi.12331. Epub 2016 Apr 29.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:19398555   PMID:20096447   PMID:21962518   PMID:22658674   PMID:22681889   PMID:24845384   PMID:25861989   PMID:35987808  



Usp10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,881,255 - 64,923,522 (+)NCBIGRCr8
mRatBN7.21947,972,858 - 48,014,900 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,972,611 - 48,014,897 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1954,767,502 - 54,809,229 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01955,448,244 - 55,489,969 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,661,267 - 57,703,079 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,566,274 - 52,608,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,566,607 - 52,608,817 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01963,313,910 - 63,356,424 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41950,202,951 - 50,244,677 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1947,229,671 - 47,271,396 (+)NCBICelera
Cytogenetic Map19q12NCBI
USP10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381684,700,000 - 84,779,922 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1684,699,986 - 84,779,922 (+)EnsemblGRCh38hg38GRCh38
GRCh371684,733,606 - 84,813,528 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361683,291,056 - 83,371,029 (+)NCBINCBI36Build 36hg18NCBI36
Build 341683,291,084 - 83,370,670NCBI
Celera1669,035,743 - 69,115,795 (+)NCBICelera
Cytogenetic Map16q24.1NCBI
HuRef1670,486,450 - 70,566,405 (+)NCBIHuRef
CHM1_11686,145,099 - 86,225,097 (+)NCBICHM1_1
T2T-CHM13v2.01690,766,262 - 90,846,179 (+)NCBIT2T-CHM13v2.0
Usp10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,637,099 - 120,684,299 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8120,637,099 - 120,684,299 (+)EnsemblGRCm39 Ensembl
GRCm388119,910,360 - 119,957,560 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8119,910,360 - 119,957,560 (+)EnsemblGRCm38mm10GRCm38
MGSCv378122,434,752 - 122,481,457 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368122,796,829 - 122,843,534 (+)NCBIMGSCv36mm8
Celera8124,131,245 - 124,177,988 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map868.61NCBI
Usp10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955541242,091 - 296,059 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955541242,182 - 296,018 (+)NCBIChiLan1.0ChiLan1.0
USP10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21894,449,698 - 94,529,802 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116100,366,823 - 100,446,915 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01665,367,463 - 65,447,549 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11684,719,540 - 84,787,714 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1684,712,913 - 84,787,714 (+)Ensemblpanpan1.1panPan2
USP10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1567,736,215 - 67,774,756 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl567,736,730 - 67,809,206 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha567,750,854 - 67,823,397 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0567,968,955 - 68,042,190 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl567,968,955 - 68,042,589 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1567,984,393 - 68,056,880 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0567,819,079 - 67,892,003 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0568,234,061 - 68,306,639 (-)NCBIUU_Cfam_GSD_1.0
Usp10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934927,554,574 - 27,618,345 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366413,307,931 - 3,350,517 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366413,308,121 - 3,350,476 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl63,977,231 - 4,043,533 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.163,977,235 - 4,043,539 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.264,473,366 - 4,491,966 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1570,105,653 - 70,186,512 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl570,139,470 - 70,185,884 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660475,563,590 - 5,644,539 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247461,554,023 - 1,617,308 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247461,553,891 - 1,616,711 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Usp10
127 total Variants


Assembly: RGSC_v3.4

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain Variant Page
19 50203043 50203044 C T snv SS/JrHsdMcwi (MCW) View more Information

Predicted Target Of
Summary Value
Count of predictions:78
Count of miRNA genes:60
Interacting mature miRNAs:71
Transcripts:ENSRNOT00000022432
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 10 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat

1 to 10 of 10 rows
BI288552  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21948,002,896 - 48,003,067 (+)MAPPERmRatBN7.2
Rnor_6.01952,596,492 - 52,596,662NCBIRnor6.0
Rnor_5.01963,344,096 - 63,344,266UniSTSRnor5.0
RGSC_v3.41950,232,674 - 50,232,844UniSTSRGSC3.4
Celera1947,259,393 - 47,259,563UniSTS
RH 3.4 Map19647.2UniSTS
Cytogenetic Map19q12UniSTS
RH129100  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21947,999,157 - 47,999,339 (+)MAPPERmRatBN7.2
Rnor_6.01952,592,753 - 52,592,934NCBIRnor6.0
Rnor_5.01963,340,357 - 63,340,538UniSTSRnor5.0
RGSC_v3.41950,228,935 - 50,229,116UniSTSRGSC3.4
Celera1947,255,654 - 47,255,835UniSTS
RH 3.4 Map19635.1UniSTS
Cytogenetic Map19q12UniSTS
RH130276  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2182,128,850 - 2,129,056 (-)MAPPERmRatBN7.2
mRatBN7.21948,014,655 - 48,014,871 (+)MAPPERmRatBN7.2
Rnor_6.01952,608,576 - 52,608,791NCBIRnor6.0
Rnor_5.01963,356,180 - 63,356,395UniSTSRnor5.0
RGSC_v3.41950,244,433 - 50,244,648UniSTSRGSC3.4
Celera1947,271,152 - 47,271,367UniSTS
RH 3.4 Map19657.2UniSTS
Cytogenetic Map19q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000022432   ⟹   ENSRNOP00000022432
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1947,990,018 - 48,014,897 (+)Ensembl
Rnor_6.0 Ensembl1952,566,607 - 52,608,817 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113547   ⟹   ENSRNOP00000079829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1947,972,611 - 48,014,897 (+)Ensembl
RefSeq Acc Id: NM_001034146   ⟹   NP_001029318
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,881,797 - 64,923,522 (+)NCBI
mRatBN7.21947,973,174 - 48,014,900 (+)NCBI
Rnor_6.01952,566,607 - 52,608,820 (+)NCBI
Rnor_5.01963,313,910 - 63,356,424 (+)NCBI
RGSC_v3.41950,202,951 - 50,244,677 (+)RGD
Celera1947,229,671 - 47,271,396 (+)RGD
Sequence:
RefSeq Acc Id: XM_008772609   ⟹   XP_008770831
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81964,881,255 - 64,923,522 (+)NCBI
mRatBN7.21947,972,858 - 48,014,900 (+)NCBI
Rnor_6.01952,566,274 - 52,608,064 (+)NCBI
Sequence:
1 to 9 of 9 rows
Protein RefSeqs NP_001029318 (Get FASTA)   NCBI Sequence Viewer  
  NP_001421448 (Get FASTA)   NCBI Sequence Viewer  
  NP_001421449 (Get FASTA)   NCBI Sequence Viewer  
  XP_008770831 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI05893 (Get FASTA)   NCBI Sequence Viewer  
  EDL92690 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000022432
  ENSRNOP00000079829
GenBank Protein Q3KR59 (Get FASTA)   NCBI Sequence Viewer  
1 to 9 of 9 rows
RefSeq Acc Id: NP_001029318   ⟸   NM_001034146
- UniProtKB: Q3KR59 (UniProtKB/Swiss-Prot),   A0A8L2QBF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008770831   ⟸   XM_008772609
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000022432   ⟸   ENSRNOT00000022432
Ensembl Acc Id: ENSRNOP00000079829   ⟸   ENSRNOT00000113547
USP

Name Modeler Protein Id AA Range Protein Structure
AF-Q3KR59-F1-model_v2 AlphaFold Q3KR59 1-794 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13701188
Promoter ID:EPDNEW_R11709
Type:initiation region
Name:Usp10_1
Description:ubiquitin specific peptidase 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01952,566,603 - 52,566,663EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-5497 BioCyc
Ensembl Genes ENSRNOG00000016509 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000022432 ENTREZGENE
  ENSRNOT00000113547 ENTREZGENE
Gene3D-CATH Cysteine proteinases UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7367339 IMAGE-MGC_LOAD
InterPro Ataxin-2_C UniProtKB/Swiss-Prot
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot
  Peptidase_C19 UniProtKB/Swiss-Prot
  Peptidase_C19_UCH UniProtKB/Swiss-Prot
  USP_CS UniProtKB/Swiss-Prot
  USP_dom UniProtKB/Swiss-Prot
KEGG Report rno:307905 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124997 IMAGE-MGC_LOAD
NCBI Gene 307905 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 10 UniProtKB/Swiss-Prot
Pfam PAM2 UniProtKB/Swiss-Prot
  UCH UniProtKB/Swiss-Prot
PhenoGen Usp10 PhenoGen
PROSITE USP_1 UniProtKB/Swiss-Prot
  USP_2 UniProtKB/Swiss-Prot
  USP_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016509 RatGTEx
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot
UniProt A0A8I5ZPC2_RAT UniProtKB/TrEMBL
  A0A8L2QBF0 ENTREZGENE, UniProtKB/TrEMBL
  A6IZL2 ENTREZGENE, UniProtKB/TrEMBL
  Q3KR59 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Usp10  ubiquitin specific peptidase 10  Usp10  ubiquitin specific protease 10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Usp10  ubiquitin specific protease 10      Symbol and Name status set to provisional 70820 PROVISIONAL