Uchl3 (ubiquitin C-terminal hydrolase L3) - Rat Genome Database

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Gene: Uchl3 (ubiquitin C-terminal hydrolase L3) Rattus norvegicus
Analyze
Symbol: Uchl3 (Ensembl: Uchl3-ps1)
Name: ubiquitin C-terminal hydrolase L3 (Ensembl:ubiquitin C-terminal hydrolase L3, pseudogene 1)
RGD ID: 1561196
Description: Predicted to enable cysteine-type deubiquitinase activity and ubiquitin binding activity. Predicted to be involved in cellular response to insulin stimulus; positive regulation of fat cell differentiation; and protein catabolic process. Predicted to act upstream of or within several processes, including adult walking behavior; eating behavior; and protein deubiquitination. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human UCHL3 (ubiquitin C-terminal hydrolase L3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC498560; RGD1561196; similar to ubiqutin carboxyl-terminal hydrolase l3; ubiquitin carboxyl-terminal esterase L3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); ubiquitin carboxyl-terminal hydrolase isozyme L3; ubiquitin thioesterase L3; UCH-L3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Uchl3-ps1  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81584,888,847 - 84,942,095 (+)NCBIGRCr8
mRatBN7.21578,485,304 - 78,527,355 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3161,856,958 - 161,857,835 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1578,485,315 - 78,527,355 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1582,496,066 - 82,538,090 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01583,572,627 - 83,614,651 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01580,493,216 - 80,535,240 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01586,153,624 - 86,198,127 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1586,153,628 - 86,198,127 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01589,919,728 - 89,964,227 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41585,628,490 - 85,670,420 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1577,676,770 - 77,718,591 (+)NCBICelera
Cytogenetic Map15q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uchl3RatDeglutition Disorders  ISOUchl3 (Mus musculus)1302546 RGD 
Uchl3RatNerve Degeneration  ISOUchl3 (Mus musculus)1302546 RGD 
Uchl3Ratneuroaxonal dystrophy  ISOUchl3 (Mus musculus)1302546 RGD 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uchl3Ratchromosome 13q14 deletion syndrome  ISOUCHL3 (Homo sapiens)8554872ClinVar Annotator: match by term: Chromosome 13q14 deletion syndromeClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uchl3RatNeoplasm Metastasis  ISOUCHL3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17085005

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uchl3Rat(1->4)-beta-D-glucan multiple interactionsISOUchl3 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of UCHL3 mRNACTDPMID:36331819
Uchl3Rat1,2-dichloroethane decreases expressionISOUchl3 (Mus musculus)6480464ethylene dichloride results in decreased expression of UCHL3 mRNACTDPMID:28960355
Uchl3Rat1H-pyrazole increases expressionISOUchl3 (Mus musculus)6480464pyrazole results in increased expression of UCHL3 mRNACTDPMID:17945193
Uchl3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUchl3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of UCHL3 mRNACTDPMID:21570461
Uchl3Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of UCHL3 mRNACTDPMID:33387578
Uchl3Rat2,6-dimethoxyphenol multiple interactionsISOUCHL3 (Homo sapiens)6480464[pyrogallol 1 more ...CTDPMID:38598786
Uchl3Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of UCHL3 mRNACTDPMID:21346803
Uchl3Rat2-hydroxypropanoic acid decreases expressionISOUCHL3 (Homo sapiens)6480464Lactic Acid results in decreased expression of UCHL3 mRNACTDPMID:30851411
Uchl3Rat4,4'-sulfonyldiphenol increases expressionISOUCHL3 (Homo sapiens)6480464bisphenol S results in increased expression of UCHL3 mRNACTDPMID:27685785
Uchl3Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of UCHL3 mRNACTDPMID:36041667
Uchl3Rat4,4'-sulfonyldiphenol multiple interactionsISOUCHL3 (Homo sapiens)6480464[bisphenol S co-treated with Fulvestrant] results in increased methylation of UCHL3 geneCTDPMID:31601247
Uchl3Rat4,4'-sulfonyldiphenol decreases expressionISOUCHL3 (Homo sapiens)6480464bisphenol S results in decreased expression of UCHL3 proteinCTDPMID:33181973
Uchl3Rat4,4'-sulfonyldiphenol increases expressionISOUchl3 (Mus musculus)6480464bisphenol S results in increased expression of UCHL3 mRNACTDPMID:39298647
Uchl3Rataflatoxin B1 increases expressionISOUCHL3 (Homo sapiens)6480464Aflatoxin B1 results in increased expression of UCHL3 mRNACTDPMID:27153756
Uchl3Rataldehydo-D-glucose increases secretionISOUCHL3 (Homo sapiens)6480464Glucose deficiency results in increased secretion of UCHL3 proteinCTDPMID:24802182
Uchl3Ratammonium chloride affects expressionEXP 6480464Ammonium Chloride affects the expression of UCHL3 mRNACTDPMID:16483693
Uchl3Ratarsane multiple interactionsISOUchl3 (Mus musculus)6480464[[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of UCHL3 protein and [methylmercuric chloride co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of UCHL3 proteinCTDPMID:32179164
Uchl3Ratarsenic atom multiple interactionsISOUchl3 (Mus musculus)6480464[[lead chloride results in increased abundance of Lead] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of UCHL3 protein and [methylmercuric chloride co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in increased expression of UCHL3 proteinCTDPMID:32179164
Uchl3Ratarsenite(3-) decreases expressionISOUchl3 (Mus musculus)6480464arsenite results in decreased expression of UCHL3 mRNACTDPMID:33053406
Uchl3Ratarsenous acid increases expressionISOUCHL3 (Homo sapiens)6480464Arsenic Trioxide results in increased expression of UCHL3 proteinCTDPMID:25419056

1 to 20 of 101 rows

Biological Process
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Uchl3Ratadult walking behavior acts_upstream_of_or_withinISOUchl3 (Mus musculus)1624291MGI:103149 PMID:11555633RGDPMID:11555633
Uchl3Ratcellular response to insulin stimulus involved_inISOUchl3 (Mus musculus)1624291 PMID:19837878RGDPMID:19837878
Uchl3Rateating behavior acts_upstream_of_or_withinISOUchl3 (Mus musculus)1624291MGI:103149 PMID:11555633RGDPMID:11555633
Uchl3Ratpositive regulation of fat cell differentiation involved_inISOUchl3 (Mus musculus)1624291 PMID:19837878RGDPMID:19837878
Uchl3Ratprotein catabolic process involved_inISOUchl3 (Mus musculus)1624291 PMID:21762696RGDPMID:21762696
Uchl3Ratprotein catabolic process involved_inIBAMGI:1355274 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Uchl3Ratprotein catabolic process involved_inISOUCHL3 (Homo sapiens)1624291 PMID:21762696RGDPMID:21762696
Uchl3Ratprotein deubiquitination involved_inISOUCHL3 (Homo sapiens)1624291 PMID:19047059 and PMID:9521656RGDPMID:19047059 and PMID:9521656
Uchl3Ratprotein deubiquitination acts_upstream_of_or_withinISOUchl3 (Mus musculus)1624291 PMID:26609154RGDPMID:26609154
Uchl3Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Uchl3Ratretina development in camera-type eye acts_upstream_of_or_withinISOUchl3 (Mus musculus)1624291 PMID:21052544RGDPMID:21052544
Uchl3Ratubiquitin-dependent protein catabolic process involved_inIEAUniRule:UR0001020781600115GO_REF:0000104UniProtGO_REF:0000104
Uchl3Ratubiquitin-dependent protein catabolic process involved_inIEAInterPro:IPR001578 and InterPro:IPR0369591600115GO_REF:0000002InterProGO_REF:0000002
1 to 13 of 13 rows

Cellular Component

  
Object Symbol
Species
Term
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Evidence
With
Reference
Notes
Source
Original Reference(s)
Uchl3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Uchl3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Uchl3Ratcytoplasm is_active_inIBAMGI:103149 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Uchl3Ratcytosol located_inISOUCHL3 (Homo sapiens)1624291 RGDGO_REF:0000052
Uchl3RatGolgi apparatus located_inISOUCHL3 (Homo sapiens)1624291 RGDGO_REF:0000052
Uchl3Ratnucleoplasm located_inISOUCHL3 (Homo sapiens)1624291 RGDGO_REF:0000052

Molecular Function
1 to 12 of 12 rows

  
1 to 12 of 12 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia. Kurihara LJ, etal., Hum Mol Genet 2001 Sep 1;10(18):1963-70.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:9521656   PMID:15632090   PMID:19154770   PMID:19837878   PMID:21052544   PMID:21762696   PMID:23376485   PMID:26609154  



Uchl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81584,888,847 - 84,942,095 (+)NCBIGRCr8
mRatBN7.21578,485,304 - 78,527,355 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3161,856,958 - 161,857,835 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl1578,485,315 - 78,527,355 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1582,496,066 - 82,538,090 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01583,572,627 - 83,614,651 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01580,493,216 - 80,535,240 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01586,153,624 - 86,198,127 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1586,153,628 - 86,198,127 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01589,919,728 - 89,964,227 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41585,628,490 - 85,670,420 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1577,676,770 - 77,718,591 (+)NCBICelera
Cytogenetic Map15q21NCBI
UCHL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381375,549,502 - 75,606,020 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1375,549,483 - 75,606,020 (+)EnsemblGRCh38hg38GRCh38
GRCh371376,123,638 - 76,180,156 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361375,021,928 - 75,078,070 (+)NCBINCBI36Build 36hg18NCBI36
Build 341375,021,927 - 75,078,067NCBI
Celera1357,021,803 - 57,077,943 (+)NCBICelera
Cytogenetic Map13q22.2NCBI
HuRef1356,821,075 - 56,877,308 (+)NCBIHuRef
CHM1_11376,091,356 - 76,147,870 (+)NCBICHM1_1
T2T-CHM13v2.01374,773,163 - 74,829,671 (+)NCBIT2T-CHM13v2.0
Uchl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914101,891,387 - 101,933,561 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl14101,891,403 - 101,933,561 (+)EnsemblGRCm39 Ensembl
GRCm3814101,653,892 - 101,696,125 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14101,653,967 - 101,696,125 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714102,053,184 - 102,095,342 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3614100,540,246 - 100,582,053 (+)NCBIMGSCv36mm8
Celera14100,293,249 - 100,335,409 (+)NCBICelera
Cytogenetic Map14E2.3NCBI
cM Map1450.9NCBI
Uchl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540431,414,208 - 31,464,968 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540431,414,076 - 31,465,205 (-)NCBIChiLan1.0ChiLan1.0
UCHL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21477,127,881 - 77,183,967 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11375,725,673 - 75,781,714 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01356,776,436 - 56,832,539 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11375,549,305 - 75,878,805 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1375,549,647 - 75,878,673 (+)Ensemblpanpan1.1panPan2
UCHL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12229,348,962 - 29,397,944 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2229,348,706 - 29,407,965 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2229,151,524 - 29,258,782 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02229,625,506 - 29,732,716 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2229,684,385 - 29,736,169 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12229,276,538 - 29,383,650 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02229,320,217 - 29,427,245 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02229,388,463 - 29,495,905 (+)NCBIUU_Cfam_GSD_1.0
Uchl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945130,107,193 - 130,163,980 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365115,522,965 - 5,581,334 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365115,524,425 - 5,581,156 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UCHL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1147,828,421 - 47,887,629 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11147,829,037 - 47,885,800 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21152,436,220 - 52,477,054 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UCHL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl354,647,590 - 54,706,497 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604610,791,194 - 10,849,805 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uchl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475124,882,705 - 24,940,105 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475124,882,580 - 24,940,301 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Uchl3
125 total Variants

Predicted Target Of
Summary Value
Count of predictions:8
Count of miRNA genes:8
Interacting mature miRNAs:8
Transcripts:ENSRNOT00000028960
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1549844Bss7Bone structure and strength QTL 76.4femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1575788062101769107Rat
2300326Plaw1Placental weight QTL 1150.005placenta mass (VT:0004257)placenta wet weight (CMO:0002088)1568327165100062518Rat
70155Gcs1Gastric cancer susceptibility QTL13.8stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)1576306099101769107Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
631516Gluco31Glucose level QTL 317blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)155559608995018120Rat
1331724Bp223Blood pressure QTL 2233.53715arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)157369051895018228Rat
2317055Aia10Adjuvant induced arthritis QTL 103.41joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1575788062101769107Rat

1 to 10 of 25 rows
Uchl4  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.43163,941,308 - 163,942,074UniSTSRGSC3.4
Celera3161,050,303 - 161,051,069UniSTS
Cytogenetic Map3q42UniSTS
Cytogenetic Map15q21UniSTS
BM390056  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21578,494,992 - 78,495,193 (-)MAPPERmRatBN7.2
mRatBN7.21578,494,992 - 78,495,193 (+)MAPPERmRatBN7.2
Rnor_6.01586,163,284 - 86,163,484NCBIRnor6.0
Rnor_6.03171,124,878 - 171,125,078NCBIRnor6.0
Rnor_5.03177,191,047 - 177,191,247UniSTSRnor5.0
Rnor_5.01589,929,384 - 89,929,584UniSTSRnor5.0
RGSC_v3.41585,638,146 - 85,638,346UniSTSRGSC3.4
Celera1577,686,426 - 77,686,626UniSTS
RH 3.4 Map15503.1UniSTS
Cytogenetic Map15q21UniSTS
Cytogenetic Map3q42UniSTS
PMC85452P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.43163,941,362 - 163,942,072UniSTSRGSC3.4
Celera3161,050,357 - 161,051,067UniSTS
Cytogenetic Map3q42UniSTS
Cytogenetic Map15q21UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
18 15 64 198 141 139 84 46 84 12 330 149 164 69 110 55


1 to 23 of 23 rows
RefSeq Transcripts NM_001110165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063274583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB043959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 23 of 23 rows

Ensembl Acc Id: ENSRNOT00000012842   ⟹   ENSRNOP00000012842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1578,485,315 - 78,527,349 (+)Ensembl
Rnor_6.0 Ensembl1586,153,628 - 86,198,127 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000028960   ⟹   ENSRNOP00000029819
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1578,496,608 - 78,527,355 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000104271   ⟹   ENSRNOP00000091247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1578,485,336 - 78,527,355 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000112431   ⟹   ENSRNOP00000092785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1578,485,336 - 78,527,355 (+)Ensembl
RefSeq Acc Id: NM_001110165   ⟹   NP_001103635
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,078 - 84,942,095 (+)NCBI
mRatBN7.21578,485,336 - 78,527,355 (+)NCBI
Rnor_6.01586,153,628 - 86,198,127 (+)NCBI
Rnor_5.01589,919,728 - 89,964,227 (+)NCBI
RGSC_v3.41585,628,490 - 85,670,420 (+)RGD
Celera1577,676,770 - 77,718,591 (+)RGD
Sequence:
RefSeq Acc Id: XM_039093599   ⟹   XP_038949527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,899,862 - 84,942,093 (+)NCBI
mRatBN7.21578,485,304 - 78,527,353 (+)NCBI
RefSeq Acc Id: XM_063274569   ⟹   XP_063130639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,899,862 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274570   ⟹   XP_063130640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274571   ⟹   XP_063130641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,098 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274572   ⟹   XP_063130642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274573   ⟹   XP_063130643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,888,847 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274574   ⟹   XP_063130644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274575   ⟹   XP_063130645
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,102 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274576   ⟹   XP_063130646
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,060 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274577   ⟹   XP_063130647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,045 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274578   ⟹   XP_063130648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,899,862 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274579   ⟹   XP_063130649
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,045 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274580   ⟹   XP_063130650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,059 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274581   ⟹   XP_063130651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274582   ⟹   XP_063130652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,051 - 84,942,093 (+)NCBI
RefSeq Acc Id: XM_063274583   ⟹   XP_063130653
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81584,900,063 - 84,942,093 (+)NCBI
1 to 30 of 30 rows
Protein RefSeqs NP_001103635 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415874 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415875 (Get FASTA)   NCBI Sequence Viewer  
  NP_001415876 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949527 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130639 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130640 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130641 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130642 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130643 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130644 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130645 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130646 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130647 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130648 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130649 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130650 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130651 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130652 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130653 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB47136 (Get FASTA)   NCBI Sequence Viewer  
  EDM02439 (Get FASTA)   NCBI Sequence Viewer  
  EDM02440 (Get FASTA)   NCBI Sequence Viewer  
  EDM02441 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012842
  ENSRNOP00000091247
  ENSRNOP00000092785
  ENSRNOP00000105849
  ENSRNOP00000112540
GenBank Protein Q91Y78 (Get FASTA)   NCBI Sequence Viewer  
1 to 30 of 30 rows
1 to 5 of 21 rows
1 to 5 of 21 rows
RefSeq Acc Id: NP_001103635   ⟸   NM_001110165
- UniProtKB: Q91Y78 (UniProtKB/Swiss-Prot),   A0A8J8Y1V7 (UniProtKB/TrEMBL),   A6KKZ2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012842   ⟸   ENSRNOT00000012842
RefSeq Acc Id: XP_038949527   ⟸   XM_039093599
- Peptide Label: isoform X15
- UniProtKB: A0A8I6AE48 (UniProtKB/TrEMBL),   A0A8J8Y1V7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000092785   ⟸   ENSRNOT00000112431
Ensembl Acc Id: ENSRNOP00000029819   ⟸   ENSRNOT00000028960
Name Modeler Protein Id AA Range Protein Structure
AF-Q91Y78-F1-model_v2 AlphaFold Q91Y78 1-230 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699863
Promoter ID:EPDNEW_R10386
Type:initiation region
Name:Uchl3_1
Description:ubiquitin C-terminal hydrolase L3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01586,153,626 - 86,153,686EPDNEW


1 to 31 of 31 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-12748 BioCyc
Ensembl Genes ENSRNOG00000009530 Ensembl, ENTREZGENE
  ENSRNOG00000065893 Ensembl
Ensembl Transcript ENSRNOT00000012842 ENTREZGENE
  ENSRNOT00000104271 ENTREZGENE
  ENSRNOT00000112431 ENTREZGENE
  ENSRNOT00000143305 ENTREZGENE
  ENSRNOT00000161380 ENTREZGENE
Gene3D-CATH 3.40.532.10 UniProtKB/Swiss-Prot
InterPro Papain-like_cys_pep_sf UniProtKB/Swiss-Prot
  Peptidase_C12_UCH UniProtKB/Swiss-Prot
  Peptidase_C12_UCH_sf UniProtKB/Swiss-Prot
KEGG Report rno:498560 UniProtKB/Swiss-Prot
NCBI Gene 498560 ENTREZGENE
PANTHER PTHR10589 UniProtKB/Swiss-Prot
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L3 UniProtKB/Swiss-Prot
Pfam Peptidase_C12 UniProtKB/Swiss-Prot
PhenoGen Uchl3 PhenoGen
PRINTS UBCTHYDRLASE UniProtKB/Swiss-Prot
PROSITE UCH_1 UniProtKB/Swiss-Prot
  UCH_DOMAIN UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000009530 RatGTEx
  ENSRNOG00000065893 RatGTEx
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot
UniProt A0A8I6AE48 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GJY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8Y1V7 ENTREZGENE, UniProtKB/TrEMBL
  A6HU77 ENTREZGENE, UniProtKB/TrEMBL
  A6KKZ2 ENTREZGENE, UniProtKB/TrEMBL
  D4ABI6_RAT UniProtKB/TrEMBL
  Q91Y78 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 31 of 31 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Uchl3  ubiquitin C-terminal hydrolase L3  Uchl3  ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-02 Uchl3  ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)  RGD1561196  similar to ubiqutin carboxyl-terminal hydrolase l3   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561196  similar to ubiqutin carboxyl-terminal hydrolase l3   RGD1561196_predicted  similar to ubiqutin carboxyl-terminal hydrolase l3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561196_predicted  similar to ubiqutin carboxyl-terminal hydrolase l3 (predicted)  LOC498560  similar to ubiqutin carboxyl-terminal hydrolase l3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498560  similar to ubiqutin carboxyl-terminal hydrolase l3      Symbol and Name status set to provisional 70820 PROVISIONAL