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Gene: Ube2k (ubiquitin-conjugating enzyme E2K) Rattus norvegicus

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Symbol:

Ube2k

Name:

ubiquitin-conjugating enzyme E2K

RGD ID:

1311626

Description:

Predicted to enable ubiquitin conjugating enzyme activity; ubiquitin protein ligase binding activity; and ubiquitin-ubiquitin ligase activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Predicted to be located in cytoplasm and filopodium tip. Predicted to be active in nucleus. Orthologous to human UBE2K (ubiquitin conjugating enzyme E2 K); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

E2-25k; Hip2; huntingtin interacting protein 2; Hypg; Lig; LOC289623; ubiquitin-conjugating enzyme E2 K; ubiquitin-conjugating enzyme E2-25K; ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UBE2K (ubiquitin conjugating enzyme E2 K)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Ube2k (ubiquitin-conjugating enzyme E2K)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ube2k (ubiquitin conjugating enzyme E2 K)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	UBE2K (ubiquitin conjugating enzyme E2 K)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	UBE2K (ubiquitin conjugating enzyme E2 K)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ube2k (ubiquitin conjugating enzyme E2 K)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	UBE2K (ubiquitin conjugating enzyme E2 K)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	UBE2K (ubiquitin conjugating enzyme E2 K)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ube2k (ubiquitin conjugating enzyme E2 K)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	SLC30A1 (solute carrier family 30 member 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	UBE2K (ubiquitin conjugating enzyme E2 K)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ube2k (ubiquitin-conjugating enzyme E2K)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ube2ka (ubiquitin-conjugating enzyme E2Ka (UBC1 homolog, yeast))	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	ube2kb (ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ubc4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	UBC1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ubc-20	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ubc-21	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	ube2k	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	43,011,681 - 43,077,825 (-)	NCBI		GRCr8
mRatBN7.2	14	42,658,016 - 42,718,899 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	42,658,016 - 42,718,630 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	43,011,647 - 43,072,105 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	44,311,686 - 44,372,016 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	42,791,658 - 42,852,126 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	44,289,247 - 44,348,691 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	44,289,247 - 44,348,691 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	44,108,859 - 44,168,755 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	45,349,287 - 45,411,823 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	45,354,342 - 45,414,183 (-)	NCBI
Celera	14	41,809,022 - 41,869,333 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ube2k	Rat	Hyperglycinemia, Lactic Acidosis, and Seizures		ISO	UBE2K (Homo sapiens)	8554872	ClinVar Annotator: match by term: HYPERGLYCINEMIA more ...	ClinVar	PMID:28492532

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ube2k	Rat	(1->4)-beta-D-glucan	multiple interactions	ISO	Ube2k (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of UBE2K mRNA	CTD	PMID:36331819
Ube2k	Rat	1,2-dichloroethane	increases expression	ISO	Ube2k (Mus musculus)	6480464	ethylene dichloride results in increased expression of UBE2K mRNA	CTD	PMID:28960355
Ube2k	Rat	1,2-dimethylhydrazine	multiple interactions	ISO	Ube2k (Mus musculus)	6480464	[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of UBE2K mRNA	CTD	PMID:22206623
Ube2k	Rat	1,2-dimethylhydrazine	decreases expression	ISO	Ube2k (Mus musculus)	6480464	1 and 2-Dimethylhydrazine results in decreased expression of UBE2K mRNA	CTD	PMID:22206623
Ube2k	Rat	17alpha-ethynylestradiol	multiple interactions	ISO	Ube2k (Mus musculus)	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE2K mRNA	CTD	PMID:17942748
Ube2k	Rat	17alpha-ethynylestradiol	increases expression	ISO	Ube2k (Mus musculus)	6480464	Ethinyl Estradiol results in increased expression of UBE2K mRNA	CTD	PMID:17555576 and PMID:17942748
Ube2k	Rat	17beta-estradiol	increases expression	ISO	Ube2k (Mus musculus)	6480464	Estradiol results in increased expression of UBE2K mRNA	CTD	PMID:39298647
Ube2k	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	Ube2k (Mus musculus)	6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBE2K mRNA	CTD	PMID:17942748
Ube2k	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Ube2k (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of UBE2K mRNA	CTD	PMID:21570461
Ube2k	Rat	2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	Ube2k (Mus musculus)	6480464	Tetrachlorodibenzodioxin results in increased expression of UBE2K mRNA	CTD	PMID:19465110
Ube2k	Rat	2,4-dinitrotoluene	affects expression	EXP		6480464	2 and 4-dinitrotoluene affects the expression of UBE2K mRNA	CTD	PMID:21346803
Ube2k	Rat	2,6-dimethoxyphenol	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in decreased expression of UBE2K protein	CTD	PMID:38598786
Ube2k	Rat	2,6-dinitrotoluene	affects expression	EXP		6480464	2 and 6-dinitrotoluene affects the expression of UBE2K mRNA	CTD	PMID:21346803
Ube2k	Rat	2-methylcholine	affects expression	ISO	UBE2K (Homo sapiens)	6480464	beta-methylcholine affects the expression of UBE2K mRNA	CTD	PMID:21179406
Ube2k	Rat	3H-1,2-dithiole-3-thione	increases expression	ISO	Ube2k (Mus musculus)	6480464	1 and 2-dithiol-3-thione results in increased expression of UBE2K mRNA	CTD	PMID:15375163
Ube2k	Rat	4,4'-sulfonyldiphenol	increases expression	ISO	Ube2k (Mus musculus)	6480464	bisphenol S results in increased expression of UBE2K mRNA	CTD	PMID:39298647
Ube2k	Rat	acetylsalicylic acid	increases expression	ISO	UBE2K (Homo sapiens)	6480464	Aspirin results in increased expression of UBE2K mRNA	CTD	PMID:11906190
Ube2k	Rat	aflatoxin B1	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Aflatoxin B1 results in decreased expression of UBE2K mRNA	CTD	PMID:21641981
Ube2k	Rat	all-trans-retinoic acid	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Tretinoin results in decreased expression of UBE2K mRNA	CTD	PMID:33167477
Ube2k	Rat	aminoglutethimide	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Aminoglutethimide results in decreased expression of UBE2K protein	CTD	PMID:26102013
Ube2k	Rat	aristolochic acid A	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	aristolochic acid I results in decreased expression of UBE2K mRNA	CTD	PMID:33212167
Ube2k	Rat	aristolochic acid A	increases expression	ISO	UBE2K (Homo sapiens)	6480464	aristolochic acid I results in increased expression of UBE2K protein	CTD	PMID:33212167
Ube2k	Rat	Aroclor 1254	decreases expression	ISO	Ube2k (Mus musculus)	6480464	Chlorodiphenyl (54% Chlorine) results in decreased expression of UBE2K mRNA	CTD	PMID:23650126
Ube2k	Rat	arsane	affects methylation	ISO	UBE2K (Homo sapiens)	6480464	Arsenic affects the methylation of UBE2K gene	CTD	PMID:25304211
Ube2k	Rat	arsenic atom	affects methylation	ISO	UBE2K (Homo sapiens)	6480464	Arsenic affects the methylation of UBE2K gene	CTD	PMID:25304211
Ube2k	Rat	atrazine	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Atrazine results in decreased expression of UBE2K mRNA	CTD	PMID:22378314
Ube2k	Rat	benzo[a]pyrene	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased expression of UBE2K mRNA	CTD	PMID:20064835
Ube2k	Rat	benzo[a]pyrene	increases expression	ISO	Ube2k (Mus musculus)	6480464	Benzo(a)pyrene results in increased expression of UBE2K mRNA	CTD	PMID:22228805 and PMID:27195522
Ube2k	Rat	benzo[a]pyrene diol epoxide I	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	7 more ...	CTD	PMID:19150397 and PMID:26238291
Ube2k	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of UBE2K mRNA	CTD	PMID:25181051
Ube2k	Rat	bisphenol A	decreases expression	ISO	Ube2k (Mus musculus)	6480464	bisphenol A results in decreased expression of UBE2K protein	CTD	PMID:35999755
Ube2k	Rat	bisphenol A	increases methylation	ISO	UBE2K (Homo sapiens)	6480464	bisphenol A results in increased methylation of UBE2K gene	CTD	PMID:31601247
Ube2k	Rat	bisphenol A	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	bisphenol A results in decreased expression of UBE2K mRNA and bisphenol A results in decreased expression of UBE2K protein	CTD	PMID:29275510 and PMID:37567409
Ube2k	Rat	bisphenol AF	increases expression	ISO	UBE2K (Homo sapiens)	6480464	bisphenol AF results in increased expression of UBE2K protein	CTD	PMID:34186270
Ube2k	Rat	Brodifacoum	increases expression	EXP		6480464	bromfenacoum results in increased expression of UBE2K protein	CTD	PMID:28903499
Ube2k	Rat	cadmium dichloride	increases expression	ISO	Ube2k (Mus musculus)	6480464	Cadmium Chloride results in increased expression of UBE2K mRNA	CTD	PMID:20061341
Ube2k	Rat	cannabidiol	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Cuprizone co-treated with Cannabidiol] results in decreased expression of UBE2K protein	CTD	PMID:34122009
Ube2k	Rat	chenodeoxycholic acid	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of UBE2K mRNA	CTD	PMID:32152650
Ube2k	Rat	chlorpyrifos	increases expression	ISO	Ube2k (Mus musculus)	6480464	Chlorpyrifos results in increased expression of UBE2K mRNA	CTD	PMID:29156651
Ube2k	Rat	cisplatin	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Cisplatin results in decreased expression of UBE2K mRNA	CTD	PMID:27594783
Ube2k	Rat	clofibrate	increases expression	ISO	Ube2k (Mus musculus)	6480464	Clofibrate results in increased expression of UBE2K mRNA	CTD	PMID:23811191
Ube2k	Rat	cobalt dichloride	increases expression	ISO	UBE2K (Homo sapiens)	6480464	cobaltous chloride results in increased expression of UBE2K mRNA	CTD	PMID:19320972
Ube2k	Rat	copper(II) sulfate	increases expression	ISO	UBE2K (Homo sapiens)	6480464	Copper Sulfate results in increased expression of UBE2K mRNA	CTD	PMID:19549813
Ube2k	Rat	Cuprizon	decreases expression	EXP		6480464	Cuprizone results in decreased expression of UBE2K mRNA	CTD	PMID:26577399
Ube2k	Rat	Cuprizon	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Cuprizone co-treated with Cannabidiol] results in decreased expression of UBE2K protein	CTD	PMID:34122009
Ube2k	Rat	cyclosporin A	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Cyclosporine results in decreased expression of UBE2K mRNA	CTD	PMID:22147139
Ube2k	Rat	cyclosporin A	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of UBE2K mRNA	CTD	PMID:32152650
Ube2k	Rat	deoxycholic acid	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of UBE2K mRNA	CTD	PMID:32152650
Ube2k	Rat	dieldrin	increases response to substance	ISO	UBE2K (Homo sapiens)	6480464	UBE2K gene mutant form results in increased susceptibility to Dieldrin	CTD	PMID:32421776
Ube2k	Rat	doxorubicin	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Doxorubicin results in decreased expression of UBE2K mRNA	CTD	PMID:29803840
Ube2k	Rat	ethanol	affects splicing	ISO	Ube2k (Mus musculus)	6480464	Ethanol affects the splicing of UBE2K mRNA	CTD	PMID:30319688
Ube2k	Rat	ethyl methanesulfonate	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Ethyl Methanesulfonate results in decreased expression of UBE2K mRNA	CTD	PMID:23649840
Ube2k	Rat	flutamide	increases expression	EXP		6480464	Flutamide results in increased expression of UBE2K mRNA	CTD	PMID:24136188
Ube2k	Rat	folic acid	multiple interactions	ISO	Ube2k (Mus musculus)	6480464	[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of UBE2K mRNA	CTD	PMID:22206623
Ube2k	Rat	formaldehyde	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Formaldehyde results in decreased expression of UBE2K mRNA	CTD	PMID:23649840
Ube2k	Rat	furan	decreases expression	EXP		6480464	furan results in decreased expression of UBE2K mRNA	CTD	PMID:25539665
Ube2k	Rat	furfural	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of UBE2K protein and [Sodium Chloride co-treated with Furaldehyde] results in increased expression of UBE2K protein	CTD	PMID:38598786
Ube2k	Rat	glycochenodeoxycholic acid	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of UBE2K mRNA	CTD	PMID:32152650
Ube2k	Rat	glycocholic acid	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of UBE2K mRNA	CTD	PMID:32152650
Ube2k	Rat	glycodeoxycholic acid	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of UBE2K mRNA	CTD	PMID:32152650
Ube2k	Rat	isotretinoin	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Isotretinoin results in decreased expression of UBE2K mRNA	CTD	PMID:20436886
Ube2k	Rat	ivermectin	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Ivermectin results in decreased expression of UBE2K protein	CTD	PMID:32959892
Ube2k	Rat	lead diacetate	affects expression	EXP		6480464	lead acetate affects the expression of UBE2K protein	CTD	PMID:36539177
Ube2k	Rat	lead(0)	affects splicing	ISO	UBE2K (Homo sapiens)	6480464	Lead affects the splicing of UBE2K mRNA	CTD	PMID:28903495
Ube2k	Rat	mechlorethamine	increases expression	ISO	Ube2k (Mus musculus)	6480464	Mechlorethamine results in increased expression of UBE2K mRNA	CTD	PMID:17107856
Ube2k	Rat	methidathion	decreases expression	ISO	Ube2k (Mus musculus)	6480464	methidathion results in decreased expression of UBE2K mRNA	CTD	PMID:34813904
Ube2k	Rat	methyl methanesulfonate	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Methyl Methanesulfonate results in decreased expression of UBE2K mRNA	CTD	PMID:23649840
Ube2k	Rat	methylmercury chloride	increases expression	ISO	Ube2k (Mus musculus)	6480464	methylmercuric chloride results in increased expression of UBE2K mRNA	CTD	PMID:20061341
Ube2k	Rat	methylmercury chloride	increases expression	ISO	UBE2K (Homo sapiens)	6480464	methylmercuric chloride results in increased expression of UBE2K mRNA	CTD	PMID:28001369
Ube2k	Rat	methylparaben	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	methylparaben results in decreased expression of UBE2K mRNA	CTD	PMID:31745603
Ube2k	Rat	N-methyl-4-phenylpyridinium	decreases expression	ISO	Ube2k (Mus musculus)	6480464	1-Methyl-4-phenylpyridinium results in decreased expression of UBE2K protein	CTD	PMID:26558463
Ube2k	Rat	nefazodone	increases expression	EXP		6480464	nefazodone results in increased expression of UBE2K mRNA	CTD	PMID:24136188
Ube2k	Rat	nimesulide	increases expression	EXP		6480464	nimesulide results in increased expression of UBE2K mRNA	CTD	PMID:24136188
Ube2k	Rat	paracetamol	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Acetaminophen results in decreased expression of UBE2K mRNA	CTD	PMID:21420995
Ube2k	Rat	pentachlorophenol	increases expression	ISO	Ube2k (Mus musculus)	6480464	Pentachlorophenol results in increased expression of UBE2K mRNA	CTD	PMID:23892564
Ube2k	Rat	perfluorooctane-1-sulfonic acid	multiple interactions	ISO	Ube2k (Mus musculus)	6480464	[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of UBE2K mRNA	CTD	PMID:36331819
Ube2k	Rat	pirinixic acid	increases expression	ISO	Ube2k (Mus musculus)	6480464	pirinixic acid results in increased expression of UBE2K mRNA	CTD	PMID:15375163 and PMID:23811191
Ube2k	Rat	rotenone	increases expression	ISO	UBE2K (Homo sapiens)	6480464	Rotenone results in increased expression of UBE2K mRNA	CTD	PMID:33512557
Ube2k	Rat	SB 431542	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of UBE2K protein	CTD	PMID:37664457
Ube2k	Rat	sodium arsenate	increases expression	ISO	Ube2k (Mus musculus)	6480464	sodium arsenate results in increased expression of UBE2K mRNA	CTD	PMID:21795629
Ube2k	Rat	sodium arsenite	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	TP53 protein affects the reaction [sodium arsenite results in increased expression of UBE2K mRNA]	CTD	PMID:16966095
Ube2k	Rat	sodium arsenite	increases expression	ISO	UBE2K (Homo sapiens)	6480464	sodium arsenite results in increased expression of UBE2K mRNA	CTD	PMID:38568856
Ube2k	Rat	sodium chloride	multiple interactions	ISO	UBE2K (Homo sapiens)	6480464	[Sodium Chloride co-treated with Furaldehyde] results in increased expression of and affects the localization of UBE2K protein more ...	CTD	PMID:38598786
Ube2k	Rat	sodium dichromate	increases expression	ISO	Ube2k (Mus musculus)	6480464	sodium bichromate results in increased expression of UBE2K mRNA	CTD	PMID:22155349
Ube2k	Rat	sodium dichromate	increases expression	EXP		6480464	sodium bichromate results in increased expression of UBE2K mRNA	CTD	PMID:22561333
Ube2k	Rat	tamoxifen	affects expression	ISO	Ube2k (Mus musculus)	6480464	Tamoxifen affects the expression of UBE2K mRNA	CTD	PMID:17555576
Ube2k	Rat	tert-butyl hydroperoxide	increases expression	ISO	UBE2K (Homo sapiens)	6480464	tert-Butylhydroperoxide results in increased expression of UBE2K mRNA	CTD	PMID:15336504
Ube2k	Rat	titanium dioxide	decreases methylation	ISO	Ube2k (Mus musculus)	6480464	titanium dioxide results in decreased methylation of UBE2K gene	CTD	PMID:35295148
Ube2k	Rat	valproic acid	affects expression	ISO	UBE2K (Homo sapiens)	6480464	Valproic Acid affects the expression of UBE2K mRNA	CTD	PMID:25979313
Ube2k	Rat	valproic acid	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	Valproic Acid results in decreased expression of UBE2K mRNA	CTD	PMID:23179753 and PMID:27188386
Ube2k	Rat	vinclozolin	decreases methylation	EXP		6480464	vinclozolin results in decreased methylation of UBE2K gene	CTD	PMID:31682807
Ube2k	Rat	vorinostat	decreases expression	ISO	UBE2K (Homo sapiens)	6480464	vorinostat results in decreased expression of UBE2K mRNA	CTD	PMID:27188386

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ube2k	Rat	cellular response to interferon-beta	involved_in	ISO	UBE2K (Homo sapiens)	1624291	PMID:24882218	RGD	PMID:24882218
Ube2k	Rat	cellular response to interferon-beta	involved_in	IEA	UniProtKB:P61086 and ensembl:ENSP00000261427	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ube2k	Rat	free ubiquitin chain polymerization	involved_in	ISO	UBE2K (Homo sapiens)	1624291	PMID:24882218	RGD	PMID:24882218
Ube2k	Rat	free ubiquitin chain polymerization	involved_in	IEA	UniProtKB:P61086 and ensembl:ENSP00000261427	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ube2k	Rat	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	acts_upstream_of_or_within	IMP		8554156	PMID:18710920	MGI
Ube2k	Rat	positive regulation of peptidyl-threonine phosphorylation	involved_in	ISO	UBE2K (Homo sapiens)	1624291	PMID:24882218	RGD	PMID:24882218
Ube2k	Rat	positive regulation of tumor necrosis factor-mediated signaling pathway	involved_in	ISO	UBE2K (Homo sapiens)	1624291	PMID:26707646	RGD	PMID:26707646
Ube2k	Rat	positive regulation of tumor necrosis factor-mediated signaling pathway	involved_in	IEA	UniProtKB:P61086 and ensembl:ENSP00000261427	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ube2k	Rat	positive regulation of type I interferon-mediated signaling pathway	involved_in	ISO	UBE2K (Homo sapiens)	1624291	PMID:24882218	RGD	PMID:24882218
Ube2k	Rat	positive regulation of type I interferon-mediated signaling pathway	involved_in	IEA	UniProtKB:P61086 and ensembl:ENSP00000261427	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ube2k	Rat	protein K48-linked ubiquitination	involved_in	ISO	UBE2K (Homo sapiens)	1624291	PMID:20061386	RGD	PMID:20061386
Ube2k	Rat	protein K48-linked ubiquitination	involved_in	IEA	UniProtKB:P61086 and ensembl:ENSP00000261427	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ube2k	Rat	protein polyubiquitination	involved_in	IBA	FB:FBgn0000173 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ube2k	Rat	regulation of proteasomal ubiquitin-dependent protein catabolic process	acts_upstream_of_or_within	ISO	Ube2k (Mus musculus)	1624291	PMID:18710920	RGD	PMID:18710920

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ube2k	Rat	cytoplasm	located_in	ISO	Ube2k (Mus musculus)	1624291	PMID:18511602	RGD	PMID:18511602
Ube2k	Rat	filopodium tip	located_in	ISO	Ube2k (Mus musculus)	1624291	PMID:18511602	RGD	PMID:18511602
Ube2k	Rat	nucleus	is_active_in	IBA	FB:FBgn0000173 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ube2k	Rat	nucleus	located_in	ISO	Ube2k (Mus musculus)	1624291	PMID:18511602	RGD	PMID:18511602

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ube2k	Rat	ATP binding	enables	IEA	UniRule:UR000141827	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Ube2k	Rat	ATP binding	enables	IEA	UniProtKB-KW:KW-0067	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ube2k	Rat	nucleotide binding	enables	IEA	UniProtKB-KW:KW-0547	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ube2k	Rat	protein binding	enables	ISO	UBE2K (Homo sapiens)	1624291	UniProtKB:O00522 more ...	RGD	PMID:17500595 more ...
Ube2k	Rat	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Ube2k	Rat	ubiquitin conjugating enzyme activity	enables	IBA	FB:FBgn0000173 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Ube2k	Rat	ubiquitin conjugating enzyme activity	enables	IEA	EC:2.3.2.23	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Ube2k	Rat	ubiquitin protein ligase binding	enables	ISO	UBE2K (Homo sapiens)	1624291	UniProtKB:P38398 more ...	RGD	PMID:16714285 more ...
Ube2k	Rat	ubiquitin protein ligase binding	enables	IEA	UniProtKB:P61086 and ensembl:ENSP00000261427	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ube2k	Rat	ubiquitin-protein transferase activity	enables	ISO	UBE2K (Homo sapiens)	1624291	PMID:20061386	RGD	PMID:20061386
Ube2k	Rat	ubiquitin-protein transferase activity	enables	IEA	UniProtKB:P61086 and ensembl:ENSP00000261427	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Ube2k	Rat	ubiquitin-ubiquitin ligase activity	enables	ISO	UBE2K (Homo sapiens)	1624291	PMID:17873885	RGD	PMID:17873885
Ube2k	Rat	ubiquitin-ubiquitin ligase activity	enables	IEA	UniProtKB:P61086 and ensembl:ENSP00000261427	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107

Imported Annotations - KEGG (archival)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Ube2k	Rat	ubiquitin/proteasome degradation pathway		IEA		6907045		KEGG	rno:04120

BioCyc Pathways

protein ubiquitination

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	E2-25K/Hip-2 regulates caspase-12 in ER stress-mediated Abeta neurotoxicity.	Song S, etal., J Cell Biol. 2008 Aug 25;182(4):675-84. doi: 10.1083/jcb.200711066. Epub 2008 Aug 18.

PMID:14760703	PMID:16714285	PMID:17873885	PMID:18410486	PMID:18511602	PMID:18729231	PMID:20061386	PMID:23376485	PMID:24882218	PMID:26707646

Ube2k
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	43,011,681 - 43,077,825 (-)	NCBI		GRCr8
mRatBN7.2	14	42,658,016 - 42,718,899 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	42,658,016 - 42,718,630 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	43,011,647 - 43,072,105 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	44,311,686 - 44,372,016 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	42,791,658 - 42,852,126 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	44,289,247 - 44,348,691 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	44,289,247 - 44,348,691 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	44,108,859 - 44,168,755 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	14	45,349,287 - 45,411,823 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	14	45,354,342 - 45,414,183 (-)	NCBI
Celera	14	41,809,022 - 41,869,333 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

UBE2K
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	39,698,136 - 39,782,792 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	39,698,109 - 39,782,792 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	4	39,699,756 - 39,784,412 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	39,376,266 - 39,457,977 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	4	39,522,436 - 39,604,148	NCBI
Celera	4	40,137,995 - 40,223,124 (+)	NCBI		Celera
Cytogenetic Map	4	p14	NCBI
HuRef	4	39,024,547 - 39,109,580 (+)	NCBI		HuRef
CHM1_1	4	39,699,339 - 39,784,070 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	39,667,902 - 39,752,430 (+)	NCBI		T2T-CHM13v2.0

Ube2k
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	65,694,588 - 65,756,332 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	65,694,576 - 65,756,331 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	65,537,245 - 65,598,989 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	65,537,233 - 65,598,988 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	65,928,500 - 65,990,228 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	65,816,406 - 65,878,063 (+)	NCBI		MGSCv36	mm8
Celera	5	62,815,933 - 62,878,205 (+)	NCBI		Celera
Cytogenetic Map	5	C3.1	NCBI
cM Map	5	33.72	NCBI

Ube2k
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955443	7,618,379 - 7,656,305 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955443	7,618,379 - 7,655,542 (-)	NCBI	ChiLan1.0	ChiLan1.0

UBE2K
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	39,886,781 - 39,972,600 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	40,079,239 - 40,164,593 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	34,026,942 - 34,111,923 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	39,877,966 - 39,960,402 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	39,877,966 - 39,960,397 (+)	Ensembl	panpan1.1		panPan2

UBE2K
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	72,713,035 - 72,780,199 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	72,717,236 - 72,780,210 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	75,259,911 - 75,327,198 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	73,485,595 - 73,553,473 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	73,485,593 - 73,553,418 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	72,752,394 - 72,820,149 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	72,898,341 - 72,966,163 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	73,284,799 - 73,352,656 (-)	NCBI		UU_Cfam_GSD_1.0

Ube2k
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	38,975,456 - 39,053,214 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936482	7,244,967 - 7,323,266 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936482	7,244,972 - 7,323,263 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

UBE2K
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	30,887,830 - 30,963,762 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	8	30,887,784 - 30,961,685 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	32,580,147 - 32,654,102 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

UBE2K
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	10,535,091 - 10,618,659 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	10,539,402 - 10,618,573 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	56,921,431 - 57,007,501 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ube2k
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624761	27,205,034 - 27,276,884 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624761	27,205,034 - 27,277,016 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Ube2k
181 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	1026
Count of miRNA genes:	346
Interacting mature miRNAs:	477
Transcripts:	ENSRNOT00000030485
Prediction methods:	Microtar, Miranda
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313089	Bss81	Bone structure and strength QTL 81	3.4	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	14	37669719	82669719	Rat
1581500	Renag1	Renal agenesis QTL 1			kidney development trait (VT:0000527)	percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)	14	8170668	68298175	Rat
10755459	Coatc15	Coat color QTL 15		0.01681	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	14	19836944	64836944	Rat
70214	Niddm28	Non-insulin dependent diabetes mellitus QTL 28	4.06		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	39998251	75582726	Rat
1300154	Bp189	Blood pressure QTL 189	3.04		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	14	30883777	68757901	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30320092	80829842	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	40793460	98037301	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8267090	53267090	Rat
2313100	Bss82	Bone structure and strength QTL 82	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	14	37669719	82669719	Rat
7387267	Uae42	Urinary albumin excretion QTL 42		0.61	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	14	22167967	67167967	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11030622	95876975	Rat
2313397	Coatc1	Coat color QTL1			coat/hair pigmentation trait (VT:0010463)	coat/hair color measurement (CMO:0001808)	14	18541332	63541332	Rat
2313048	Bss84	Bone structure and strength QTL 84	3.1	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	14	37669719	82669719	Rat
1300136	Rf22	Renal function QTL 22	3.9		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	14	42262529	95023211	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8267090	53267090	Rat
738037	Hcas6	Hepatocarcinoma susceptibility QTL 6	2.93		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	14	39057237	83368335	Rat
2313084	Bss83	Bone structure and strength QTL 83	2.9	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	14	37669719	82669719	Rat

RH130202

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	42,659,388 - 42,659,586 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	44,290,620 - 44,290,817	NCBI	Rnor6.0
Rnor_5.0	14	44,110,232 - 44,110,429	UniSTS	Rnor5.0
RGSC_v3.4	14	45,350,660 - 45,350,857	UniSTS	RGSC3.4
Celera	14	41,810,395 - 41,810,592	UniSTS
Cytogenetic Map	14	p11	UniSTS

RH141776

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	42,663,184 - 42,663,375 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	44,294,416 - 44,294,606	NCBI	Rnor6.0
Rnor_5.0	14	44,114,028 - 44,114,218	UniSTS	Rnor5.0
RGSC_v3.4	14	45,354,456 - 45,354,646	UniSTS	RGSC3.4
Celera	14	41,814,191 - 41,814,381	UniSTS
Cytogenetic Map	14	p11	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001106006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091716	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272925	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272927	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226880	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ233155	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000030485 ⟹ ENSRNOP00000032265

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	42,658,016 - 42,718,554 (-)	Ensembl
Rnor_6.0 Ensembl	14	44,289,247 - 44,348,691 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099891 ⟹ ENSRNOP00000085062

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	42,658,016 - 42,713,094 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103920 ⟹ ENSRNOP00000085882

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	42,661,971 - 42,718,630 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000105695 ⟹ ENSRNOP00000079243

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	42,658,016 - 42,718,342 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116564 ⟹ ENSRNOP00000096375

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	42,662,024 - 42,718,548 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118995 ⟹ ENSRNOP00000083068

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	42,662,172 - 42,718,554 (-)	Ensembl

RefSeq Acc Id:

NM_001106006 ⟹ NP_001099476

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	43,011,681 - 43,072,214 (-)	NCBI
mRatBN7.2	14	42,658,016 - 42,718,554 (-)	NCBI
Rnor_6.0	14	44,289,247 - 44,348,691 (-)	NCBI
Rnor_5.0	14	44,108,859 - 44,168,755 (-)	NCBI
RGSC_v3.4	14	45,349,287 - 45,411,823 (-)	RGD
Celera	14	41,809,022 - 41,869,333 (-)	RGD

Sequence:

show sequence

GCGCATGCGCGGACCCGGCGCCATTTTGGTGGCCGGGCGCGGAGGTGATTCTACACTGAGGGGGAACGCGACGGCAAGGGTGGCAGTGGCAGCGTTCGTGTGCTCGGGTCTGAATCACTGAGGGAGGA
GGCGGTGGAGGAAGAGGTGGCAGCGGTGGCGGTGGTCGTAGCGGTGGCGGAGGAGGCGGGTACGAATCAGCTGCGGGCAGAGACATGGCCAACATCGCGGTGCAGCGAATCAAGCGGGAGTTCAAGGA
GGTGCTGAAGAGCGAGGAGACGAGCAAAAATCAAATTAAAGTAGATCTTGTAGATGAGAATTTTACAGAATTAAGAGGAGAAATAGCAGGACCTCCAGACACACCGTATGAAGGTGGAAGATATCAAC
TAGAGATAAAAATACCAGAAACATATCCATTTAACCCCCCTAAGGTCCGGTTTATCACTAAAATATGGCACCCTAATATTAGTTCCGTCACAGGGGCTATTTGTTTGGATATCCTGAAAGATCAATGG
GCAGCAGCAATGACTCTGCGCACAGTATTATTGTCATTGCAAGCACTGCTGGCCGCTGCAGAACCAGATGACCCCCAAGATGCAGTAGTAGCAAATCAGTACAAACAAAATCCTGAAATGTTCAAGCA
GACAGCTCGACTTTGGGCACACGTGTATGCTGGAGCACCAGTGTCTAGTCCAGAATACACCAAAAAAATAGAAAACCTCTGTGCTATGGGTTTTGATAGGAACGCAGTAATAGTGGCCTTGTCTTCAA
AATCATGGGATGTAGAGACTGCAACAGAACTGCTTCTGAGTAACTGAGGCACAGGAGCTGCCAGCCACGCTCGCCCCTTCCTGAGGAGCGTCCACACCTGTCATTTTTAGGATTCTGCATAAATTTCT
TTTAAACTGGCATTCTTGCCTAATGATGTTACCTAGGCACCATTGGAGACTGCAAAAAAAAAAAAAAAAATTACCTGCTCTGTAAATAAAGCTAATTAAACGTCTGTGTAAATTTAAAAAGGGAAAAT
ACTTTAATTTTTTTCTTGGTAGTGTAAAAATCCTTTGAGCTAAGCTAAAACCATGGGAAAACATGCTACTTTAGTGTTTAGCAGTGTGACAGACTAGTGAGTTTGCTTCAGGGTTCTGTTGAGTAACT
AGGATAACACTCGAGTGTTGGCCCTACCTTGTGGAGTAGCATCACAGTCCCTCAAGCCTGAACATGGATCCTCTGTGCCTGTGACTTACTTGCATGCTTGACCTCTTAGAACGGGTAGCTGAAAGACC
ACCCTTTTAAGCGTTAGGACATTTTTGAATTATGAGATTTATCCTGATTTAAAGATGGTGACCTAATCAGAGCTTTTTCGTCCCTGTGGACTGGTGGGGACTGTCTTTTTTCCTTGTCACCATCCAGA
GTGGAGAGTCTCATGGTCAGTTTCTTTTGTGTTTGGTGGGAAACGTGCTGAGGAACAGTGTCCCGTGTTCCACTTTTAGCTCATAGGTTTGGAATGTTTTGTCCAAGCTCTTCACTTTGTAAGTAGGA
ATGTAACAAAGGAGCTGCCAATTTCATTTCTCTTATAAAAGGAGAAAATACTTGATGTTGCAGTATTTCCAGATTTAATAAAAGGACACTGCTTAGTTTTTCAGTGATTTTGACATTAAGTTTTAAAA
TGATAAAGTCTTTGGAAACTTGAAGGGTGCAGCACCTGTCCCCTCGTGCTCAGCCTGAGTTGGGCGTGACAGTTTTCTTTGTCAGACACTTGAGTTACTGCACTCCCCATGTTGACACACGAAAGCTG
TGGTGTCTCGCTGTACATACCAGATGCACATAGGAACAGGGGTGTGCTCTAAATCTAGCTTTTTATGATGTTTCTGATAATGTGAGAATTGAAACTTTACCTTTTCTTGTACATAGACTTCCTGTCCT
TAGTAACTGTCGTATCTCATTCTAAGTTCCAAAGCTTGAAAATTAATAGTTTTGCAAATTGGTTTTGCAAACTCAGATACTTAATTTAACCATCTTTATTAAGGTTCAAGTGAATTTATGTAGGCAGT
TGTTACATAGGAGATATAATTAAAGATTTTGAGAACCAATGCATAAATTACAGAAATGTAATGGAATCAGACTGAGTTAAAGTAAGGCTGTATGTATATTGAAAGTCATATTCTAAAAGGTTTGTTTC
TCGAAGAGTTGATTGATCTTATAGTCATGAAGTATTTCAAAAATACTTTCTGAACCTATTAACTCAGCATAACTTCATTTGACTTTTAATAATCTCGATACTACAAGCAATAAATGAGCCATCAATAC
ATTACATTACAGATGTGAAGGTTCTTCCAGCAGCTCATAAGGCTTTCCCAGTCAACAGTGACTTGGGCTCGCTGCCCTGCACTAAGCTCAGGCTGCTGCTCCCCATGTCTGTGATGCACACATTCCCG
CCCGCGGCAGCTACATCCTTATTGCTGTAGGTCATTTTATAAAGATGCCAAAGGAGACAAGGTTTTCTTTATTTTCAATAGCTGGGACTTTGTCTTTTTCTTTATCTTCTCAGATAAGCTGGAAATGT
CAGAAATTCTGGACCGTTGACCTCCGTTGTCAGTTAGGACTGTTTAATGGAGGGTGGTAACATTGATATTTAGGTATGGAAATGCATACATCTTCCTTGCATTCCTCTCTGCCTGCATTGTCAGGGCG
TAGTGTCTGGGTAGACGTCAAGCAGCACCACTTTGTCTTGGAGGCAGCTGTTTCTACTTATTGTCTTTTTTTTTTTTTTTTTTGGTTCTTTTTTTTCGGAGCTGGGGACTGAACCCAGGGCCTTGCGC
TTCCTAGGTAAGCGCTCTACCACTGAGCTAAATCCCCAGACCCTTTGTTTTTTATTTTATATTTTTTGCATATTGGTTTCAGACAGCTTCCATGTGTGCATATAACATGGTGTCATAGATTTTACATG
ATTATGCTATCATCTCTGTGACCCTAGAACTTGGGTGTGAGAACCATGAACTCAAGGCTGTCCAGGTTTCATACACCAGGCTGCTTGGGGGTTTTCTTCATTTAATATGATCATAGACCTTCTGTGGG
ACTTCCTCACTGTTCTCCTGGTGGTCTTTTTATTCTTTTATTTCCCATCTTGTAGGTTTAGTTCATCTTAAAGCAGAGGCTTAGGCTTCTATCCTGGTTTTACATACATTTAGGAAAACTACTCAAAA
TCTAGATCTAGTAAAACTTGCCCCGATGGAAATTATTTTTGTAAATTTCATTTGAGAGTTTATCATCTTAGTGAGTCCTGAAAAGGTTCTGTCTTGGTCTAGGCGTGGTGGCGCCTTTACTCCCATGC
TCTGGAAAGGGAAAGGCAGGCAGCTTCTGTGAGACACCTCGTGGGAGGTGTGTGTCCAGTCTTAACCCCTACTCCACAGTCTTAGTGAAATCCCAGTTAGGATTCCTTGGTACTCGCTGGTCCTCTGA
CATGCTTTTACATAATCCAGCCTTTTTTTCCTGAGCCTATGCCTGACTTTTAGTATAAAACTTTGAGCATGTTGGGAACTTTGAATTCAAAAAACATGTAAGTGTTTGGAATCAAATATTTTGCCTTT
GAGAAGTGTAACTTACCTATCAAATGAGATTAAAACATTTTTTGAAATTTTTTTATATTTCTGATTGTTGATGGCATTTAACACTATGCAAAAACTCAAGTATCTGCAGAAAACAGTTGACAGCGGGC
TTCGCTCCCACTGTAGAACACAGCGTGTTATATATCACTGGTGAGGCTGTTGACCAAGTTGACAAATGTGGAAGCCGGGTTGTGAGCGTAGGCCTCACACAGCTTTTAAAACTGCAGGAGAGTTACGG
TTTTGCAGTCTAGTGTAGCAGCACAGAAGTGAAGTTTCGGTAGGGTACGGGCTTAATGCGAATTTGGGAATCAGCAGTGGAGTCAGGTATACTGTACATAGATGGATTCCATGTGTAGATGGGAAAAG
GAAGGTATCTGTTCATACTGAGCTTTATTTCATGACTGATAAAACTGTTCTGTATTAATTACTTTTTCTAGTTCCAAGGAGTTGATCTTTCAAGTCACATTTTCATCTTTCAGAATCTGGTTTAAGTC
AGCGTGTGCCCATCAGCCTGTTGGTGTCACTGAGGAACAGCCTTTTCTCGAACAGTGTCTACGGTTCTGATGCACAGATACACTGTTTGCAGTGTTGCAATGCAGAGAACAAACTGCAGCTTACATTG
GTGCGGGTGAGGGTGGGGGTTGTTGGCGTTTCCCTTACCTATCTTGCTACTGCTTTCTCAGACTGCCAGAACCCCTGCCTGCAGGCGTCACTGGAAGGTGTCCCGATTGTGTTGTCTGTGGCATGGTT
ACTCCCACCACGCTGCTGTTTGTCCTCAGGTGTGGCACAGGTCTCTTTGGTTCTAGGCAAGTGGATCAAGTCACTGCACTGTGCTTTCACTGATCGTGTCTGCTTACCGTCACCTACTTATACAGGCA
TCATAAAAGCTAGACAATTTCTTTGGGGGAAAAGAGACTTATTTAATGTAATTTAAAGAGTTTTCCAATAAAAAATGGAATATTATTAAATATCTATTTTTAGCTTTCAGCCTTTGATGGTGCTTTGT
CGTGCTTTGCTGGAAGCTACTGACGTTATAGGGATTTCCATTAACCTCACTTTGGAAGAGCCTTGCTTGTTAGCTTCTTTAGGTCTCTGAACAGTTTGTTAGTGATGGTAAATTCTGTAGGAGGGTCT
ATTCTGAGCCATTAACTTCTTGTAAGGGGAAAACGGGCTGGTTACCAGAAACACTGCTGAAGCAGGGCGGCTGTGGGTGGAGGGTCGGGCGTCTGTCTTGAGAATTAAAAACTACGAAACACTTTTGT
ATACAAATTTTTAAAAAAAAATAAACACATTTTTAAAGATGTTGAACTTTCCCCCTTATTGGGAATTCTTAAAAATAAATGCATGCACATTCCCCCCCGCCCCCCGT

hide sequence

RefSeq Acc Id:

XM_039091716 ⟹ XP_038947644

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	43,015,636 - 43,077,825 (-)	NCBI
mRatBN7.2	14	42,659,353 - 42,718,899 (-)	NCBI

RefSeq Acc Id:

XM_039091717 ⟹ XP_038947645

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	43,015,636 - 43,072,270 (-)	NCBI
mRatBN7.2	14	42,659,353 - 42,718,548 (-)	NCBI

RefSeq Acc Id:

XM_063272925 ⟹ XP_063128995

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	43,015,636 - 43,072,152 (-)	NCBI

RefSeq Acc Id:

XM_063272926 ⟹ XP_063128996

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	43,015,636 - 43,071,961 (-)	NCBI

RefSeq Acc Id:

XM_063272927 ⟹ XP_063128997

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	43,015,636 - 43,039,156 (-)	NCBI


Protein RefSeqs	NP_001099476	(Get FASTA)	NCBI Sequence Viewer
	XP_038947644	(Get FASTA)	NCBI Sequence Viewer
	XP_038947645	(Get FASTA)	NCBI Sequence Viewer
	XP_063128995	(Get FASTA)	NCBI Sequence Viewer
	XP_063128996	(Get FASTA)	NCBI Sequence Viewer
	XP_063128997	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL90055	(Get FASTA)	NCBI Sequence Viewer
	EDL90056	(Get FASTA)	NCBI Sequence Viewer
	EDL90057	(Get FASTA)	NCBI Sequence Viewer
	EDL90058	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032265.5
	ENSRNOP00000079243
	ENSRNOP00000079243.1
	ENSRNOP00000083068.1
	ENSRNOP00000085062.1
	ENSRNOP00000085882.1
	ENSRNOP00000096375.1
	ENSRNOP00000104117

RefSeq Acc Id:

NP_001099476 ⟸ NM_001106006

- UniProtKB:

A6JDD4 (UniProtKB/TrEMBL), A0A8I6AV01 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MANIAVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAGPPDTPYEGGRYQLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDILKDQWAAAMTLRTVLLSLQALLAAAEPDDPQDA
VVANQYKQNPEMFKQTARLWAHVYAGAPVSSPEYTKKIENLCAMGFDRNAVIVALSSKSWDVETATELLLSN

hide sequence

Ensembl Acc Id:

ENSRNOP00000032265 ⟸ ENSRNOT00000030485

RefSeq Acc Id:	XP_038947644 ⟸ XM_039091716
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A2L8 (UniProtKB/TrEMBL), A0A8I6AV01 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038947645 ⟸ XM_039091717
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5ZMB3 (UniProtKB/TrEMBL), A6JDD3 (UniProtKB/TrEMBL), A0A8I6AV01 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000079243 ⟸ ENSRNOT00000105695

Protein Domains

UBA UBC core

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZXS8-F1-model_v2	AlphaFold	D3ZXS8	1-200	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13699311

Promoter ID:

EPDNEW_R9836

Type:

initiation region

Name:

Ube2k_1

Description:

ubiquitin-conjugating enzyme E2K

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	44,348,663 - 44,348,723	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-15749	BioCyc
BioCyc Pathway	PWY-7511 [protein ubiquitination]	BioCyc
BioCyc Pathway Image	PWY-7511	BioCyc
Ensembl Genes	ENSRNOG00000027088	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000030485.6	UniProtKB/TrEMBL
	ENSRNOT00000099891.1	UniProtKB/TrEMBL
	ENSRNOT00000103920.1	UniProtKB/TrEMBL
	ENSRNOT00000105695	ENTREZGENE
	ENSRNOT00000105695.1	UniProtKB/TrEMBL
	ENSRNOT00000116564.1	UniProtKB/TrEMBL
	ENSRNOT00000118995.1	UniProtKB/TrEMBL
	ENSRNOT00000170213	ENTREZGENE
Gene3D-CATH	3.10.110.10	UniProtKB/TrEMBL
	DNA helicase RuvA subunit, C-terminal domain	UniProtKB/TrEMBL
InterPro	Ub_conjugating_enzyme	UniProtKB/TrEMBL
	UBA-like	UniProtKB/TrEMBL
	UBA/transl_elong_EF1B_N_euk	UniProtKB/TrEMBL
	UBE2K_UBA	UniProtKB/TrEMBL
	UBQ-conjugat_E2	UniProtKB/TrEMBL
	UBQ-conjugating_AS	UniProtKB/TrEMBL
	UBQ-conjugating_enzyme/RWD	UniProtKB/TrEMBL
KEGG Report	rno:289623	UniProtKB/TrEMBL
NCBI Gene	289623	ENTREZGENE
PANTHER	UBIQUITIN-CONJUGATING ENZYME E2	UniProtKB/TrEMBL
	UBIQUITIN-CONJUGATING ENZYME E2	UniProtKB/TrEMBL
Pfam	UBA	UniProtKB/TrEMBL
	UQ_con	UniProtKB/TrEMBL
PhenoGen	Ube2k	PhenoGen
PROSITE	UBA	UniProtKB/TrEMBL
	UBIQUITIN_CONJUGAT_1	UniProtKB/TrEMBL
	UBIQUITIN_CONJUGAT_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000027088	RatGTEx
SMART	UBA	UniProtKB/TrEMBL
	UBCc	UniProtKB/TrEMBL
Superfamily-SCOP	UBA_like	UniProtKB/TrEMBL
	UBQ-conjugat/RWD-like	UniProtKB/TrEMBL
UniProt	A0A8I5ZMB3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZYF7_RAT	UniProtKB/TrEMBL
	A0A8I6A2L8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A356_RAT	UniProtKB/TrEMBL
	A0A8I6AV01	ENTREZGENE, UniProtKB/TrEMBL
	A6JDD3	ENTREZGENE, UniProtKB/TrEMBL
	A6JDD4	ENTREZGENE, UniProtKB/TrEMBL
	A6JDD5	ENTREZGENE, UniProtKB/TrEMBL
	D3ZXS8_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-08-01	Ube2k	ubiquitin-conjugating enzyme E2K	Ube2k	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-05-15	Ube2k	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	Hip2	huntingtin interacting protein 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Hip2	huntingtin interacting protein 2	Hip2_predicted	huntingtin interacting protein 2 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Hip2_predicted	huntingtin interacting protein 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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