Usp28 (ubiquitin specific peptidase 28) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Usp28 (ubiquitin specific peptidase 28) Rattus norvegicus
Analyze
Symbol: Usp28
Name: ubiquitin specific peptidase 28
RGD ID: 1311555
Description: Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including intracellular signal transduction; protein deubiquitination involved in ubiquitin-dependent protein catabolic process; and response to ionizing radiation. Predicted to be located in nuclear body. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Orthologous to human USP28 (ubiquitin specific peptidase 28); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3-hydroxyisovaleric acid.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: deubiquitinating enzyme; deubiquitinating enzyme 28; LOC315639; ubiquitin carboxyl-terminal hydrolase 28; ubiquitin specific protease 28; ubiquitin thioesterase 28; ubiquitin thiolesterase 28; ubiquitin-specific-processing protease 28
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8858,222,258 - 58,282,711 (+)NCBIGRCr8
mRatBN7.2849,325,766 - 49,386,229 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl849,325,867 - 49,386,229 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx854,831,791 - 54,892,095 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0853,110,659 - 53,170,968 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0850,974,908 - 51,035,219 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0853,295,188 - 53,355,572 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl853,295,222 - 53,355,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0851,909,256 - 51,969,623 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4852,245,642 - 52,305,922 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1852,280,014 - 52,324,051 (+)NCBI
Celera848,883,162 - 48,943,411 (+)NCBICelera
Cytogenetic Map8q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp28Ratchromosome 11 partial duplication syndrome  ISOUSP28 (Homo sapiens)8554872ClinVar Annotator: match by term: Distal trisomy 11qClinVarPMID:25741868
Usp28Ratintellectual disability  ISOUSP28 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Usp28Ratprostate cancer  ISOUSP28 (Homo sapiens)8554872ClinVar Annotator: match by term: Malignant tumor of prostateClinVar 
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp28RatProstatic Neoplasms  ISOUSP28 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:29610475 and PMID:29662167

1 to 20 of 80 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp28Rat1,2-dimethylhydrazine decreases expressionISOUsp28 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of USP28 mRNACTDPMID:22206623
Usp28Rat1,3-dinitrobenzene increases expressionEXP 64804643-dinitrobenzene results in increased expression of USP28 mRNACTDPMID:24140754
Usp28Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOUsp28 (Mus musculus)64804642 more ...CTDPMID:31388691
Usp28Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOUsp28 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of USP28 mRNACTDPMID:19465110
Usp28Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of USP28 mRNACTDPMID:33387578
Usp28Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUsp28 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of USP28 mRNACTDPMID:21570461
Usp28Rat2-hydroxypropanoic acid decreases expressionISOUSP28 (Homo sapiens)6480464Lactic Acid results in decreased expression of USP28 mRNACTDPMID:30851411
Usp28Rat3-hydroxyisovaleric acid increases expressionEXP 6480464beta-hydroxyisovaleric acid results in increased expression of USP28 mRNACTDPMID:24124592
Usp28Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of USP28 mRNACTDPMID:24780913 and PMID:30047161
Usp28Ratamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of USP28 mRNACTDPMID:30047161
Usp28Rataristolochic acid A decreases expressionISOUSP28 (Homo sapiens)6480464aristolochic acid I results in decreased expression of USP28 mRNACTDPMID:33212167
Usp28Ratarsenous acid increases expressionISOUsp28 (Mus musculus)6480464Arsenic Trioxide results in increased expression of USP28 mRNACTDPMID:35676786
Usp28Ratbelinostat increases expressionISOUSP28 (Homo sapiens)6480464belinostat results in increased expression of USP28 mRNACTDPMID:26272509
Usp28Ratbelinostat multiple interactionsISOUSP28 (Homo sapiens)6480464[NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of USP28 mRNACTDPMID:27188386
Usp28Ratbenzo[a]pyrene increases mutagenesisISOUSP28 (Homo sapiens)6480464Benzo(a)pyrene results in increased mutagenesis of USP28 geneCTDPMID:25435355
Usp28Ratbenzo[a]pyrene decreases methylationISOUSP28 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of USP28 promoterCTDPMID:27901495
Usp28Ratbenzo[a]pyrene affects methylationISOUSP28 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of USP28 intronCTDPMID:30157460
Usp28Ratbenzo[a]pyrene decreases expressionISOUsp28 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of USP28 mRNACTDPMID:22228805
Usp28Ratbeta-lapachone increases expressionISOUSP28 (Homo sapiens)6480464beta-lapachone results in increased expression of USP28 mRNACTDPMID:38218311
Usp28Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of USP28 mRNACTDPMID:25181051

1 to 20 of 80 rows

Biological Process
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp28Ratcell population proliferation involved_inISOUSP28 (Homo sapiens)1624291 PMID:17558397RGDPMID:17558397
Usp28Ratcell population proliferation involved_inISSUniProtKB:Q96RU21600115GO_REF:0000024UniProtGO_REF:0000024
Usp28Ratcellular response to UV involved_inISOUSP28 (Homo sapiens)1624291 PMID:17873522RGDPMID:17873522
Usp28RatDNA damage checkpoint signaling involved_inISOUSP28 (Homo sapiens)1624291 PMID:18662541RGDPMID:18662541
Usp28RatDNA damage checkpoint signaling involved_inIBAPANTHER:PTN002768249 and UniProtKB:Q96RU21600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp28RatDNA damage checkpoint signaling involved_inISSUniProtKB:Q96RU21600115GO_REF:0000024UniProtGO_REF:0000024
Usp28RatDNA damage response involved_inISOUSP28 (Homo sapiens)1624291 PMID:17873522RGDPMID:17873522
Usp28RatDNA damage response involved_inIEAUniProtKB-KW:KW-02271600115GO_REF:0000043UniProtGO_REF:0000043
Usp28RatDNA repair involved_inIEAUniProtKB-KW:KW-02341600115GO_REF:0000043UniProtGO_REF:0000043
Usp28Ratintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator involved_inISSUniProtKB:Q96RU21600115GO_REF:0000024UniProtGO_REF:0000024
Usp28Ratintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator involved_inISOUSP28 (Homo sapiens)1624291 PMID:16901786RGDPMID:16901786
Usp28Ratprotein deubiquitination involved_inISSUniProtKB:Q96RU21600115GO_REF:0000024UniProtGO_REF:0000024
Usp28Ratprotein deubiquitination involved_inIEAInterPro:IPR0013941600115GO_REF:0000002InterProGO_REF:0000002
Usp28Ratprotein deubiquitination involved_inISOUSP28 (Homo sapiens)1624291 PMID:16901786 more ...RGDPMID:16901786 more ...
Usp28Ratprotein deubiquitination involved in ubiquitin-dependent protein catabolic process involved_inISOUSP28 (Homo sapiens)1624291 PMID:24623306RGDPMID:24623306
Usp28Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Usp28Ratregulation of protein stability involved_inISSUniProtKB:Q96RU21600115GO_REF:0000024UniProtGO_REF:0000024
Usp28Ratregulation of protein stability involved_inIBAFB:FBgn0016756 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp28Ratregulation of protein stability involved_inISOUSP28 (Homo sapiens)1624291 PMID:24623306RGDPMID:24623306
Usp28Ratresponse to ionizing radiation involved_inISSUniProtKB:Q96RU21600115GO_REF:0000024UniProtGO_REF:0000024
1 to 20 of 21 rows

Cellular Component
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp28Ratcytosol is_active_inIBAFB:FBgn0016756 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp28Ratnuclear body located_inISOUSP28 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Usp28Ratnucleoplasm located_inISSUniProtKB:Q96RU21600115GO_REF:0000024UniProtGO_REF:0000024
Usp28Ratnucleoplasm located_inIEAUniProtKB-SubCell:SL-01901600115GO_REF:0000044UniProtGO_REF:0000044
Usp28Ratnucleoplasm located_inISOUSP28 (Homo sapiens) more ...1624291 RGDGO_REF:0000052
Usp28Ratnucleoplasm located_inISOUSP28 (Homo sapiens)1624291 PMID:17558397RGDPMID:17558397
Usp28Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Usp28Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Usp28Ratnucleus is_active_inIBAFB:FBgn0016756 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp28Ratprotein-containing complex part_ofISOUSP28 (Homo sapiens)1624291 PMID:17873522RGDPMID:17873522
1 to 10 of 10 rows

Molecular Function
1 to 11 of 11 rows

  
1 to 11 of 11 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:16901786   PMID:17558397   PMID:17873522   PMID:18662541   PMID:24623306   PMID:30149918  



Usp28
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8858,222,258 - 58,282,711 (+)NCBIGRCr8
mRatBN7.2849,325,766 - 49,386,229 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl849,325,867 - 49,386,229 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx854,831,791 - 54,892,095 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0853,110,659 - 53,170,968 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0850,974,908 - 51,035,219 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0853,295,188 - 53,355,572 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl853,295,222 - 53,355,572 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0851,909,256 - 51,969,623 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4852,245,642 - 52,305,922 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1852,280,014 - 52,324,051 (+)NCBI
Celera848,883,162 - 48,943,411 (+)NCBICelera
Cytogenetic Map8q23NCBI
USP28
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811113,797,875 - 113,875,572 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11113,797,874 - 113,875,572 (-)EnsemblGRCh38hg38GRCh38
GRCh3711113,668,597 - 113,746,294 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611113,173,807 - 113,251,466 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411113,173,807 - 113,251,466NCBI
Celera11110,821,475 - 110,899,132 (-)NCBICelera
Cytogenetic Map11q23.2NCBI
HuRef11109,597,124 - 109,674,696 (-)NCBIHuRef
CHM1_111113,551,888 - 113,629,830 (-)NCBICHM1_1
T2T-CHM13v2.011113,808,211 - 113,885,899 (-)NCBIT2T-CHM13v2.0
Usp28
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39948,896,577 - 48,953,817 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl948,896,675 - 48,953,817 (+)EnsemblGRCm39 Ensembl
GRCm38948,985,319 - 49,042,517 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl948,985,375 - 49,042,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv37948,793,490 - 48,850,622 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36948,737,317 - 48,794,449 (+)NCBIMGSCv36mm8
Celera946,282,655 - 46,339,797 (+)NCBICelera
Cytogenetic Map9A5.3NCBI
cM Map926.56NCBI
Usp28
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541215,426,159 - 15,443,023 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541215,425,136 - 15,469,819 (-)NCBIChiLan1.0ChiLan1.0
USP28
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29114,541,035 - 114,618,841 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111115,635,396 - 115,713,169 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011108,676,566 - 108,754,372 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111112,519,147 - 112,595,076 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11112,517,693 - 112,595,585 (-)Ensemblpanpan1.1panPan2
USP28
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1519,431,313 - 19,480,709 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl519,435,451 - 19,479,640 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha519,338,576 - 19,404,153 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0519,435,675 - 19,501,359 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl519,437,389 - 19,501,355 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1519,499,600 - 19,565,243 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0519,400,925 - 19,465,977 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0519,448,052 - 19,514,120 (+)NCBIUU_Cfam_GSD_1.0
Usp28
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494795,900,690 - 95,962,848 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936612742,725 - 804,921 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936612742,777 - 804,919 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP28
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl941,417,564 - 41,480,994 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1941,417,560 - 41,481,044 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2946,178,504 - 46,217,852 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP28
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11105,175,116 - 105,257,163 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1105,175,067 - 105,257,102 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604320,764,288 - 20,844,351 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp28
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247849,303,745 - 9,378,105 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247849,302,741 - 9,352,127 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Usp28
129 total Variants

Predicted Target Of
Summary Value
Count of predictions:244
Count of miRNA genes:90
Interacting mature miRNAs:110
Transcripts:ENSRNOT00000009724, ENSRNOT00000067420
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 61 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83085640475856404Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)830848154101699754Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)84186687686866876Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83084815461290444Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84269268490165460Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)830848154101699754Rat
1582222Epfw2Epididymal fat weight QTL 23.20.0005epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)83173772976737729Rat
1354627Despr14Despair related QTL 140.0056locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)8768895552688955Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)83558203280582032Rat

1 to 10 of 61 rows
BF413316  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2849,381,722 - 49,381,816 (+)MAPPERmRatBN7.2
Rnor_6.0853,351,067 - 53,351,160NCBIRnor6.0
Rnor_5.0851,965,118 - 51,965,211UniSTSRnor5.0
RGSC_v3.4852,301,417 - 52,301,510UniSTSRGSC3.4
Celera848,938,906 - 48,938,999UniSTS
RH 3.4 Map8524.0UniSTS
Cytogenetic Map8q23UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 23 of 23 rows
RefSeq Transcripts NM_001108144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436507 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039081445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB240643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC097700 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 23 of 23 rows

Ensembl Acc Id: ENSRNOT00000009724   ⟹   ENSRNOP00000009724
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl849,340,687 - 49,386,229 (+)Ensembl
Rnor_6.0 Ensembl853,295,222 - 53,355,323 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000067420   ⟹   ENSRNOP00000060005
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl849,325,937 - 49,386,229 (+)Ensembl
Rnor_6.0 Ensembl853,295,292 - 53,355,572 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099397   ⟹   ENSRNOP00000090131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl849,325,937 - 49,386,229 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102592   ⟹   ENSRNOP00000091262
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl849,325,867 - 49,386,229 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119039   ⟹   ENSRNOP00000083392
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl849,325,937 - 49,386,229 (+)Ensembl
RefSeq Acc Id: NM_001108144   ⟹   NP_001101614
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,429 - 58,282,711 (+)NCBI
mRatBN7.2849,325,937 - 49,386,229 (+)NCBI
Rnor_6.0853,295,292 - 53,355,572 (+)NCBI
Rnor_5.0851,909,256 - 51,969,623 (+)NCBI
RGSC_v3.4852,245,642 - 52,305,922 (+)RGD
Celera848,883,162 - 48,943,411 (+)RGD
Sequence:
RefSeq Acc Id: XM_006243006   ⟹   XP_006243068
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,289 - 58,282,700 (+)NCBI
mRatBN7.2849,325,766 - 49,386,223 (+)NCBI
Rnor_6.0853,295,188 - 53,355,563 (+)NCBI
Rnor_5.0851,909,256 - 51,969,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243007   ⟹   XP_006243069
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,289 - 58,282,700 (+)NCBI
mRatBN7.2849,325,828 - 49,386,223 (+)NCBI
Rnor_6.0853,295,188 - 53,355,563 (+)NCBI
Rnor_5.0851,909,256 - 51,969,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243008   ⟹   XP_006243070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,289 - 58,282,700 (+)NCBI
mRatBN7.2849,325,766 - 49,386,223 (+)NCBI
Rnor_6.0853,295,188 - 53,355,563 (+)NCBI
Rnor_5.0851,909,256 - 51,969,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243009   ⟹   XP_006243071
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,289 - 58,282,700 (+)NCBI
mRatBN7.2849,325,766 - 49,386,223 (+)NCBI
Rnor_6.0853,295,188 - 53,355,563 (+)NCBI
Rnor_5.0851,909,256 - 51,969,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243010   ⟹   XP_006243072
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,289 - 58,282,700 (+)NCBI
mRatBN7.2849,325,828 - 49,386,223 (+)NCBI
Rnor_6.0853,295,188 - 53,355,563 (+)NCBI
Rnor_5.0851,909,256 - 51,969,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243011   ⟹   XP_006243073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,258 - 58,282,700 (+)NCBI
mRatBN7.2849,325,766 - 49,386,223 (+)NCBI
Rnor_6.0853,295,188 - 53,355,563 (+)NCBI
Rnor_5.0851,909,256 - 51,969,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006243012   ⟹   XP_006243074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,289 - 58,282,700 (+)NCBI
mRatBN7.2849,325,829 - 49,386,223 (+)NCBI
Rnor_6.0853,295,188 - 53,355,563 (+)NCBI
Rnor_5.0851,909,256 - 51,969,623 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039081444   ⟹   XP_038937372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,289 - 58,274,578 (+)NCBI
mRatBN7.2849,325,766 - 49,378,148 (+)NCBI
RefSeq Acc Id: XM_039081445   ⟹   XP_038937373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,254,864 - 58,282,700 (+)NCBI
mRatBN7.2849,358,382 - 49,386,223 (+)NCBI
RefSeq Acc Id: XM_063265441   ⟹   XP_063121511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,289 - 58,282,700 (+)NCBI
RefSeq Acc Id: XM_063265442   ⟹   XP_063121512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,222,289 - 58,282,700 (+)NCBI
RefSeq Acc Id: XM_063265443   ⟹   XP_063121513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8858,254,867 - 58,282,700 (+)NCBI
1 to 5 of 18 rows
1 to 5 of 18 rows
RefSeq Acc Id: NP_001101614   ⟸   NM_001108144
- UniProtKB: A0A0H2UI12 (UniProtKB/TrEMBL),   A0A8I6AFT3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243071   ⟸   XM_006243009
- Peptide Label: isoform X4
- UniProtKB: A0A140TAA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243068   ⟸   XM_006243006
- Peptide Label: isoform X1
- UniProtKB: A0A140TAA0 (UniProtKB/TrEMBL),   A0A8I5ZWX4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243069   ⟸   XM_006243007
- Peptide Label: isoform X2
- UniProtKB: A0A140TAA0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006243070   ⟸   XM_006243008
- Peptide Label: isoform X3
- UniProtKB: D2Y8W6 (UniProtKB/Swiss-Prot),   D3ZJ96 (UniProtKB/Swiss-Prot),   A0A8I6AFT3 (UniProtKB/TrEMBL)
- Sequence:
UIM   USP

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZJ96-F1-model_v2 AlphaFold D3ZJ96 1-1083 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13695958
Promoter ID:EPDNEW_R6464
Type:initiation region
Name:Usp28_1
Description:ubiquitin specific peptidase 28
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0853,295,191 - 53,295,251EPDNEW


1 to 40 of 40 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-30590 BioCyc
Ensembl Genes ENSRNOG00000007325 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000067420 ENTREZGENE
  ENSRNOT00000067420.5 UniProtKB/Swiss-Prot
  ENSRNOT00000099397 ENTREZGENE
  ENSRNOT00000102592 ENTREZGENE
  ENSRNOT00000119039 ENTREZGENE
Gene3D-CATH 6.10.250.1720 UniProtKB/Swiss-Prot
  Cysteine proteinases UniProtKB/Swiss-Prot
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot
InterPro Papain-like_cys_pep_sf UniProtKB/Swiss-Prot
  Peptidase_C19 UniProtKB/Swiss-Prot
  Peptidase_C19_UCH UniProtKB/Swiss-Prot
  UBA-like_sf UniProtKB/Swiss-Prot
  UBA_8 UniProtKB/Swiss-Prot
  USP25/28_UIM UniProtKB/Swiss-Prot
  USP_CS UniProtKB/Swiss-Prot
  USP_dom UniProtKB/Swiss-Prot
KEGG Report rno:315639 UniProtKB/Swiss-Prot
NCBI Gene 315639 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 28 UniProtKB/Swiss-Prot
Pfam UBA_8 UniProtKB/Swiss-Prot
  UCH UniProtKB/Swiss-Prot
  USP_UIM_N UniProtKB/Swiss-Prot
PhenoGen Usp28 PhenoGen
PROSITE USP_1 UniProtKB/Swiss-Prot
  USP_2 UniProtKB/Swiss-Prot
  USP_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007325 RatGTEx
Superfamily-SCOP SSF46934 UniProtKB/Swiss-Prot
  SSF54001 UniProtKB/Swiss-Prot
UniProt A0A0H2UI12 ENTREZGENE, UniProtKB/TrEMBL
  A0A140TAA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZWX4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8Q3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AFT3 ENTREZGENE, UniProtKB/TrEMBL
  D2Y8W6 ENTREZGENE
  D3ZJ96 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary D2Y8W6 UniProtKB/Swiss-Prot
1 to 40 of 40 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Usp28  ubiquitin specific peptidase 28  Usp28_predicted  ubiquitin specific protease 28 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Usp28_predicted  ubiquitin specific protease 28 (predicted)      Symbol and Name status set to approved 70820 APPROVED