Rras (RAS related) - Rat Genome Database

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Gene: Rras (RAS related) Rattus norvegicus
Analyze
Symbol: Rras
Name: RAS related
RGD ID: 1311443
Description: Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in several processes, including face morphogenesis; positive regulation of endothelial cell-matrix adhesion via fibronectin; and regulation of intracellular signal transduction. Predicted to act upstream of or within negative regulation of Schwann cell migration. Predicted to be active in plasma membrane. Orthologous to human RRAS (RAS related); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Harvey rat sarcoma oncogene, subgroup R; Harvey rat sarcoma virus oncogene, subgroup R; LOC361568; p23; ras-related protein R-Ras; Ras-related protein R-RAS (P23); RAS-related viral oncoprotein; related RAS viral (r-ras) oncogene homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,637,061 - 104,640,841 (+)NCBIGRCr8
mRatBN7.2195,500,582 - 95,504,362 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,500,566 - 95,504,357 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,885,980 - 100,889,760 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,358,646 - 109,362,426 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,649,041 - 102,652,821 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,012,822 - 101,016,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,012,822 - 101,016,720 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,077,775 - 102,081,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,490,730 - 95,495,462 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,568,807 - 95,573,563 (+)NCBI
Celera189,761,925 - 89,765,705 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



  
Object Symbol
Species
Term
Qualifier
Evidence
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Reference
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Original Reference(s)
RrasRatCOVID-19  ISORRAS (Homo sapiens)9068941mRNA:increased expression:peripheral blood mononuclear cell (human)RGDPMID:32228226 and REF_RGD_ID:28912744
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Original Reference(s)
RrasRatdevelopmental and epileptic encephalopathy 12  ISORRAS (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 12ClinVarPMID:28492532
RrasRatNoonan syndrome  ISORRAS (Homo sapiens)8554872ClinVar more ...ClinVarPMID:17576681 more ...
RrasRatNoonan syndrome  ISORRAS (Homo sapiens)8554872ClinVar more ...ClinVarPMID:17576681 more ...
Object Symbol
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Evidence
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Original Reference(s)
RrasRatjuvenile myelomonocytic leukemia  ISORRAS (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26457647
RrasRatProstatic Neoplasms  ISORRAS (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17013881

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Original Reference(s)
RrasRat(-)-alpha-phellandrene increases expressionISORRAS (Homo sapiens)6480464alpha phellandrene results in increased expression of RRAS mRNACTDPMID:25075043
RrasRat(1->4)-beta-D-glucan multiple interactionsISORras (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RRAS mRNACTDPMID:36331819
RrasRat1,1-dichloroethene increases expressionISORras (Mus musculus)6480464vinylidene chloride results in increased expression of RRAS mRNACTDPMID:26682919
RrasRat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of RRAS mRNACTDPMID:30723492
RrasRat17beta-estradiol decreases expressionISORRAS (Homo sapiens)6480464Estradiol results in decreased expression of RRAS mRNACTDPMID:16029874
RrasRat17beta-estradiol multiple interactionsISORRAS (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in increased expression of RRAS mRNACTDPMID:30165855
RrasRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORras (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RRAS mRNACTDPMID:21570461
RrasRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of RRAS mRNACTDPMID:33387578 and PMID:34747641
RrasRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORRAS (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of RRAS mRNACTDPMID:20106945 and PMID:21632981
RrasRat2,6-dimethoxyphenol multiple interactionsISORRAS (Homo sapiens)6480464[Sodium Chloride co-treated with pyrogallol 1 and 3-dimethyl ether] results in increased expression of and affects the localization of RRAS proteinCTDPMID:38598786
RrasRat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of RRAS proteinCTDPMID:34915118
RrasRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISORras (Mus musculus)6480464[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in decreased expression of RRAS mRNACTDPMID:16054899
RrasRat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISORRAS (Homo sapiens)6480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of RRAS mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of RRAS mRNACTDPMID:28628672
RrasRat4-hydroxyphenyl retinamide decreases expressionISORras (Mus musculus)6480464Fenretinide results in decreased expression of RRAS mRNACTDPMID:16467112 and PMID:28973697
RrasRat5-aza-2'-deoxycytidine affects expressionISORRAS (Homo sapiens)6480464Decitabine affects the expression of RRAS mRNACTDPMID:23300844
RrasRat5-fluorouracil affects response to substanceISORRAS (Homo sapiens)6480464RRAS protein affects the susceptibility to FluorouracilCTDPMID:16217747
RrasRataconitine increases expressionEXP 6480464Aconitine results in increased expression of RRAS proteinCTDPMID:33236894
RrasRatactinomycin D increases expressionISORRAS (Homo sapiens)6480464Dactinomycin results in increased expression of RRAS mRNACTDPMID:21527772
RrasRataflatoxin B1 increases expressionISORRAS (Homo sapiens)6480464Aflatoxin B1 results in increased expression of RRAS mRNACTDPMID:21527772 and PMID:27153756
RrasRatall-trans-retinoic acid decreases expressionEXP 6480464Tretinoin results in decreased expression of RRAS mRNACTDPMID:20488242

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Biological Process
1 to 20 of 24 rows

  
Object Symbol
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Original Reference(s)
RrasRatcell migration acts_upstream_ofISORras (Mus musculus)1624291MGI:97306 PMID:14724565RGDPMID:14724565
RrasRatcell migration acts_upstream_ofIEAUniProtKB:P10833 and ensembl:ENSMUSP000000421501600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatface morphogenesis involved_inISORRAS (Homo sapiens)1624291 PMID:24705357RGDPMID:24705357
RrasRatface morphogenesis involved_inIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatleukocyte differentiation involved_inISORRAS (Homo sapiens)1624291 PMID:24705357RGDPMID:24705357
RrasRatleukocyte differentiation involved_inIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatnegative regulation of Schwann cell migration acts_upstream_of_or_withinISORras (Mus musculus)1624291MGI:97306 PMID:14724565RGDPMID:14724565
RrasRatnegative regulation of Schwann cell migration acts_upstream_of_or_withinIEAUniProtKB:P10833 and ensembl:ENSMUSP000000421501600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatpositive regulation of angiogenesis involved_inISSUniProtKB:P103011600115GO_REF:0000024UniProtGO_REF:0000024
RrasRatpositive regulation of angiogenesis involved_inIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatpositive regulation of angiogenesis involved_inISORRAS (Homo sapiens)1624291 PMID:21393242RGDPMID:21393242
RrasRatpositive regulation of endothelial cell migration involved_inISORRAS (Homo sapiens)1624291 PMID:22825554RGDPMID:22825554
RrasRatpositive regulation of endothelial cell migration involved_inIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatpositive regulation of endothelial cell-matrix adhesion via fibronectin involved_inISORRAS (Homo sapiens)1624291 PMID:22825554RGDPMID:22825554
RrasRatpositive regulation of endothelial cell-matrix adhesion via fibronectin involved_inIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatpositive regulation of vasculogenesis involved_inISORRAS (Homo sapiens)1624291 PMID:22825554RGDPMID:22825554
RrasRatpositive regulation of vasculogenesis involved_inIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatregulation of ERK1 and ERK2 cascade involved_inISORRAS (Homo sapiens)1624291 PMID:24705357RGDPMID:24705357
RrasRatregulation of ERK1 and ERK2 cascade involved_inIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatregulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_inISORRAS (Homo sapiens)1624291 PMID:24705357RGDPMID:24705357
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Cellular Component

  
Object Symbol
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Original Reference(s)
RrasRatmembrane located_inIEAInterPro:IPR0208491600115GO_REF:0000002InterProGO_REF:0000002
RrasRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
RrasRatplasma membrane is_active_inIBACGD:CAL0000184093 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
RrasRatplasma membrane located_inIEAUniProtKB-KW:KW-10031600115GO_REF:0000043UniProtGO_REF:0000043
RrasRatplasma membrane located_inIEAUniProtKB-SubCell:SL-00391600115GO_REF:0000044UniProtGO_REF:0000044

Molecular Function
1 to 16 of 16 rows

  
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Original Reference(s)
RrasRatGDP binding enablesISORRAS (Homo sapiens)1624291 PMID:16773572 and PMID:24705357RGDPMID:16773572 and PMID:24705357
RrasRatGDP binding enablesIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatGDP binding enablesIBAPANTHER:PTN000631348 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
RrasRatGTP binding enablesIEAInterPro:IPR001806 more ...1600115GO_REF:0000002InterProGO_REF:0000002
RrasRatGTP binding enablesIBAMGI:108053 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
RrasRatGTP binding enablesIEAUniProtKB-KW:KW-03421600115GO_REF:0000043UniProtGO_REF:0000043
RrasRatGTPase activity enablesISORRAS (Homo sapiens)1624291 PMID:16773572 and PMID:24705357RGDPMID:16773572 and PMID:24705357
RrasRatGTPase activity enablesIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
RrasRatGTPase activity enablesIEAInterPro:IPR0018061600115GO_REF:0000002InterProGO_REF:0000002
RrasRatGTPase activity enablesIBACGD:CAL0000181665 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
RrasRathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
RrasRatnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
RrasRatprotein binding enablesIPIUniProtKB:O087738554645PMID:19319189UniProt 
RrasRatprotein binding enablesISORRAS (Homo sapiens)1624291UniProtKB:O43157 more ...RGDPMID:17474147 more ...
RrasRatprotein-containing complex binding enablesISORRAS (Homo sapiens)1624291 PMID:23209302RGDPMID:23209302
RrasRatprotein-containing complex binding enablesIEAUniProtKB:P10301 and ensembl:ENSP000002467921600115GO_REF:0000107EnsemblGO_REF:0000107
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Imported Annotations - KEGG (archival)

Object Symbol
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Reference
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Source
Original Reference(s)
RrasRatmitogen activated protein kinase signaling pathway   IEA 6907045 KEGGrno:04010

Imported Annotations - PID (archival)

Object Symbol
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Evidence
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Reference
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Source
Original Reference(s)
RrasRatephrin - ephrin receptor bidirectional signaling axis  ISORRAS (Homo sapiens)6484113 PIDPID:200052

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector. Willard FS, etal., PLoS One. 2009;4(3):e4884. doi: 10.1371/journal.pone.0004884. Epub 2009 Mar 25.
PMID:14724565   PMID:15297673   PMID:16773572   PMID:19056867   PMID:21393242   PMID:21423176   PMID:22825554   PMID:23209302   PMID:23376485   PMID:24705357  



Rras
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,637,061 - 104,640,841 (+)NCBIGRCr8
mRatBN7.2195,500,582 - 95,504,362 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,500,566 - 95,504,357 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1100,885,980 - 100,889,760 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,358,646 - 109,362,426 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,649,041 - 102,652,821 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,012,822 - 101,016,720 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,012,822 - 101,016,720 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,077,775 - 102,081,673 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,490,730 - 95,495,462 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1195,568,807 - 95,573,563 (+)NCBI
Celera189,761,925 - 89,765,705 (+)NCBICelera
Cytogenetic Map1q22NCBI
RRAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,635,292 - 49,640,143 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,635,292 - 49,640,143 (-)EnsemblGRCh38hg38GRCh38
GRCh371950,138,549 - 50,143,400 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,830,364 - 54,835,212 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,830,363 - 54,835,212NCBI
Celera1947,007,883 - 47,012,731 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,515,612 - 46,520,460 (-)NCBIHuRef
CHM1_11950,140,333 - 50,145,181 (-)NCBICHM1_1
T2T-CHM13v2.01952,635,325 - 52,640,178 (-)NCBIT2T-CHM13v2.0
Rras
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,665,686 - 44,671,070 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,667,385 - 44,671,071 (+)EnsemblGRCm39 Ensembl
GRCm38745,017,942 - 45,021,646 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,017,961 - 45,021,647 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,273,377 - 52,277,014 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,886,049 - 44,889,686 (+)NCBIMGSCv36mm8
Celera740,469,567 - 40,473,202 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.08NCBI
Rras
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,244,658 - 1,248,774 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,244,658 - 1,248,774 (+)NCBIChiLan1.0ChiLan1.0
RRAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,752,559 - 55,757,421 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,673,302 - 57,678,161 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,649,892 - 46,654,754 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,569,465 - 55,571,444 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,569,749 - 55,573,721 (-)Ensemblpanpan1.1panPan2
RRAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11106,895,413 - 106,899,265 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1106,895,408 - 106,899,222 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,479,192 - 106,483,049 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,416,876 - 107,420,728 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,416,878 - 107,420,685 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,089,085 - 107,092,934 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,731,174 - 106,735,018 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,572,304 - 107,576,157 (+)NCBIUU_Cfam_GSD_1.0
Rras
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,838,491 - 21,842,354 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,456,290 - 3,460,788 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,456,681 - 3,460,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RRAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,680,600 - 54,684,719 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,680,596 - 54,684,714 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2650,409,620 - 50,413,729 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RRAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,810,411 - 42,815,504 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,810,339 - 42,815,479 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,754,154 - 22,759,266 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rras
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248324,633,326 - 4,637,938 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248324,632,812 - 4,637,938 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rras
24 total Variants

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:55
Interacting mature miRNAs:59
Transcripts:ENSRNOT00000027809
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 45 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat

1 to 10 of 45 rows
Rras  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81104,640,630 - 104,640,761 (+)Marker Load Pipeline
mRatBN7.2195,504,151 - 95,504,283 (+)MAPPERmRatBN7.2
Rnor_6.01101,016,510 - 101,016,641NCBIRnor6.0
Rnor_5.01102,081,463 - 102,081,594UniSTSRnor5.0
RGSC_v3.4195,495,252 - 95,495,383UniSTSRGSC3.4
Celera189,765,495 - 89,765,626UniSTS
Cytogenetic Map1q22UniSTS
AI573426  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,504,077 - 95,504,195 (+)MAPPERmRatBN7.2
Rnor_6.01101,016,436 - 101,016,553NCBIRnor6.0
Rnor_5.01102,081,389 - 102,081,506UniSTSRnor5.0
RGSC_v3.4195,495,178 - 95,495,295UniSTSRGSC3.4
Celera189,765,421 - 89,765,538UniSTS
Cytogenetic Map1q22UniSTS
BF403987  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,501,045 - 95,501,188 (+)MAPPERmRatBN7.2
Rnor_6.01101,013,286 - 101,013,428NCBIRnor6.0
Rnor_5.01102,078,239 - 102,078,381UniSTSRnor5.0
RGSC_v3.4195,491,194 - 95,491,335UniSTSRGSC3.4
Celera189,762,389 - 89,762,531UniSTS
Cytogenetic Map1q22UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000027809   ⟹   ENSRNOP00000027809
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,500,566 - 95,504,357 (+)Ensembl
Rnor_6.0 Ensembl1101,012,822 - 101,016,720 (+)Ensembl
RefSeq Acc Id: NM_001108481   ⟹   NP_001101951
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,637,061 - 104,640,841 (+)NCBI
mRatBN7.2195,500,582 - 95,504,362 (+)NCBI
Rnor_6.01101,012,822 - 101,016,720 (+)NCBI
Rnor_5.01102,077,775 - 102,081,673 (+)NCBI
RGSC_v3.4195,490,730 - 95,495,462 (+)RGD
Celera189,761,925 - 89,765,705 (+)RGD
Sequence:
RefSeq Acc Id: XM_039082165   ⟹   XP_038938093
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,637,313 - 104,640,838 (+)NCBI
mRatBN7.2195,500,835 - 95,504,359 (+)NCBI
Protein RefSeqs NP_001101951 (Get FASTA)   NCBI Sequence Viewer  
  XP_038938093 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D3Z8L7 (Get FASTA)   NCBI Sequence Viewer  
  EDM07427 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027809
  ENSRNOP00000027809.4
GenBank Protein QST76895 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001101951   ⟸   NM_001108481
- UniProtKB: D3Z8L7 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027809   ⟸   ENSRNOT00000027809
RefSeq Acc Id: XP_038938093   ⟸   XM_039082165
- Peptide Label: isoform X1

Name Modeler Protein Id AA Range Protein Structure
AF-D3Z8L7-F1-model_v2 AlphaFold D3Z8L7 1-218 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690018
Promoter ID:EPDNEW_R543
Type:initiation region
Name:Rras_1
Description:RAS related
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01101,012,803 - 101,012,863EPDNEW


1 to 28 of 28 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-59733 BioCyc
Ensembl Genes ENSRNOG00000037247 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027809 ENTREZGENE
  ENSRNOT00000027809.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
InterPro P-loop_NTPase UniProtKB/Swiss-Prot
  Small_GTP-bd_dom UniProtKB/Swiss-Prot
  Small_GTPase UniProtKB/Swiss-Prot
  Small_GTPase_Ras-type UniProtKB/Swiss-Prot
KEGG Report rno:361568 UniProtKB/Swiss-Prot
NCBI Gene 361568 ENTREZGENE
PANTHER PTHR24070 UniProtKB/Swiss-Prot
Pfam Ras UniProtKB/Swiss-Prot
PhenoGen Rras PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/Swiss-Prot
PROSITE RAS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000037247 RatGTEx
SMART RAB UniProtKB/Swiss-Prot
  RAN UniProtKB/Swiss-Prot
  RAS UniProtKB/Swiss-Prot
  RHO UniProtKB/Swiss-Prot
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
UniProt A0A8A1U964_RAT UniProtKB/TrEMBL
  A0A8A1UA40_RAT UniProtKB/TrEMBL
  A0A8A1UAN5_RAT UniProtKB/TrEMBL
  A0A8A1UBD2_RAT UniProtKB/TrEMBL
  A0A8A1UBN5_RAT UniProtKB/TrEMBL
  D3Z8L7 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 28 of 28 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-16 Rras  RAS related  Rras  related RAS viral (r-ras) oncogene homolog  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-09-29 Rras  related RAS viral (r-ras) oncogene homolog  Rras  Harvey rat sarcoma virus oncogene, subgroup R  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-20 Rras  Harvey rat sarcoma virus oncogene, subgroup R  Rras  Harvey rat sarcoma oncogene, subgroup R   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Rras  Harvey rat sarcoma oncogene, subgroup R   Rras_predicted  Harvey rat sarcoma oncogene, subgroup R (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rras_predicted  Harvey rat sarcoma oncogene, subgroup R (predicted)      Symbol and Name status set to approved 70820 APPROVED