Rras2 (RAS related 2) - Rat Genome Database

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Gene: Rras2 (RAS related 2) Rattus norvegicus
Analyze
Symbol: Rras2
Name: RAS related 2
RGD ID: 1310793
Description: Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to act upstream of or within Ras protein signal transduction and positive regulation of Schwann cell migration. Predicted to be located in endomembrane system. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 12. Orthologous to human RRAS2 (RAS related 2); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC365355; MGC109327; ras-related protein R-Ras2; related RAS viral (r-ras) oncogene homolog 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81177,668,143 - 177,737,551 (-)NCBIGRCr8
mRatBN7.21168,233,693 - 168,303,111 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1168,233,693 - 168,303,111 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1176,562,741 - 176,632,090 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,748,814 - 183,818,172 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01176,462,863 - 176,532,658 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01178,940,515 - 179,010,257 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1178,940,516 - 179,010,257 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01185,908,263 - 185,978,450 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41172,026,262 - 172,097,710 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11172,162,371 - 172,233,819 (-)NCBI
Celera1166,086,473 - 166,155,650 (-)NCBICelera
Cytogenetic Map1q33NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rras2Ratgenetic disease  ISORRAS2 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:25741868 more ...
Rras2Ratintellectual disability  ISORRAS2 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
Rras2RatNoonan syndrome  ISORRAS2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Rras2RatNoonan syndrome 12  ISORRAS2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Rras2RatOvarian Neoplasms  ISORRAS2 (Homo sapiens)8554872ClinVar Annotator: match by term: Ovarian neoplasmClinVarPMID:25741868 more ...
Rras2RatRASopathy  ISORRAS2 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:25741868 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rras2RatExperimental Liver Neoplasms  ISORRAS2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21147764
Rras2Ratjuvenile myelomonocytic leukemia  ISORRAS2 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:26457647
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rras2RatNoonan syndrome 12  ISORRAS2 (Homo sapiens)7240710 OMIM 

1 to 20 of 147 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rras2Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RRAS2 mRNA]CTDPMID:31150632
Rras2Rat1,1-dichloroethene increases expressionISORras2 (Mus musculus)6480464vinylidene chloride results in increased expression of RRAS2 mRNACTDPMID:26682919
Rras2Rat1,2-dimethylhydrazine affects expressionISORras2 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of RRAS2 mRNACTDPMID:22206623
Rras2Rat1,2-dimethylhydrazine multiple interactionsISORras2 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RRAS2 mRNACTDPMID:22206623
Rras2Rat1,3-dinitrobenzene increases expressionEXP 64804643-dinitrobenzene results in increased expression of RRAS2 mRNACTDPMID:22841810
Rras2Rat1-naphthyl isothiocyanate multiple interactionsISORRAS2 (Homo sapiens)6480464[1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of RRAS2 mRNACTDPMID:27344345
Rras2Rat17alpha-ethynylestradiol multiple interactionsISORras2 (Mus musculus)6480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RRAS2 mRNACTDPMID:17942748
Rras2Rat17alpha-ethynylestradiol increases expressionISORras2 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of RRAS2 mRNACTDPMID:17942748
Rras2Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISORras2 (Mus musculus)64804642 more ...CTDPMID:31388691
Rras2Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORras2 (Mus musculus)6480464[Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of RRAS2 mRNA and [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RRAS2 mRNACTDPMID:16214954 and PMID:17942748
Rras2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of RRAS2 mRNACTDPMID:34747641
Rras2Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORras2 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of RRAS2 mRNACTDPMID:21570461
Rras2Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionISORras2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in decreased expression of RRAS2 mRNACTDPMID:19770486
Rras2Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORras2 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of RRAS2 mRNACTDPMID:15328365 and PMID:18796159
Rras2Rat2-(chloromethyl)pyridine increases expressionISORRAS2 (Homo sapiens)64804642-chloromethylpyridine results in increased expression of RRAS2 mRNACTDPMID:26198647
Rras2Rat2-butoxyethanol decreases expressionISORras2 (Mus musculus)6480464n-butoxyethanol results in decreased expression of RRAS2 mRNACTDPMID:19812364
Rras2Rat3,4-methylenedioxymethamphetamine increases expressionISORras2 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of RRAS2 mRNACTDPMID:19285098
Rras2Rat4,4'-sulfonyldiphenol increases expressionISORras2 (Mus musculus)6480464bisphenol S results in increased expression of RRAS2 mRNACTDPMID:39298647
Rras2Rat5-aza-2'-deoxycytidine affects expressionISORRAS2 (Homo sapiens)6480464Decitabine affects the expression of RRAS2 mRNACTDPMID:23300844
Rras2Rat5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expressionEXP 6480464Omeprazole affects the expression of RRAS2 mRNACTDPMID:19483382

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Biological Process
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rras2Ratbiological_process  ND 159840702/07: no relevant rat dataRGD 
Rras2Ratcell migration acts_upstream_ofISORras2 (Mus musculus)1624291MGI:97306 PMID:14724565RGDPMID:14724565
Rras2Ratcell migration acts_upstream_ofIEAUniProtKB:P62071 and ensembl:ENSMUSP000000697521600115GO_REF:0000107EnsemblGO_REF:0000107
Rras2Ratpositive regulation of Schwann cell migration acts_upstream_of_or_withinIEAUniProtKB:P62071 and ensembl:ENSMUSP000000697521600115GO_REF:0000107EnsemblGO_REF:0000107
Rras2Ratpositive regulation of Schwann cell migration acts_upstream_of_or_withinISORras2 (Mus musculus)1624291MGI:97306 PMID:14724565RGDPMID:14724565
Rras2RatRas protein signal transduction involved_inISORRAS2 (Homo sapiens)1624291 PMID:31130282RGDPMID:31130282
Rras2RatRas protein signal transduction acts_upstream_of_or_withinIEAUniProtKB:P62071 and ensembl:ENSMUSP000000697521600115GO_REF:0000107EnsemblGO_REF:0000107
Rras2RatRas protein signal transduction acts_upstream_of_or_withinISORras2 (Mus musculus)1624291 PMID:11788587RGDPMID:11788587
Rras2RatRas protein signal transduction involved_inIEAUniProtKB:P62070 and ensembl:ENSP000002561961600115GO_REF:0000107EnsemblGO_REF:0000107
Rras2RatSchwann cell migration acts_upstream_ofIEAUniProtKB:P62071 and ensembl:ENSMUSP000000697521600115GO_REF:0000107EnsemblGO_REF:0000107
Rras2RatSchwann cell migration acts_upstream_ofISORras2 (Mus musculus)1624291MGI:97306 PMID:14724565RGDPMID:14724565
Rras2Ratsignal transduction involved_inIEAInterPro:IPR0208491600115GO_REF:0000002InterProGO_REF:0000002
1 to 12 of 12 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rras2Ratendomembrane system located_inIEAUniProtKB-SubCell:SL-01471600115GO_REF:0000044UniProtGO_REF:0000044
Rras2Ratmembrane located_inIEAInterPro:IPR0208491600115GO_REF:0000002InterProGO_REF:0000002
Rras2Ratplasma membrane is_active_inISORRAS2 (Homo sapiens)1624291 PMID:28406396RGDPMID:28406396
Rras2Ratplasma membrane is_active_inIEAUniProtKB:P62070 and ensembl:ENSP000002561961600115GO_REF:0000107EnsemblGO_REF:0000107
Rras2Ratplasma membrane is_active_inIBACGD:CAL0000184093 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rras2RatGDP binding enablesIBAPANTHER:PTN000631348 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rras2RatGTP binding enablesIEAInterPro:IPR001806 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Rras2RatGTP binding enablesIEAUniProtKB-KW:KW-03421600115GO_REF:0000043UniProtGO_REF:0000043
Rras2RatGTP binding enablesIBAMGI:108053 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rras2RatGTPase activity enablesISORRAS2 (Homo sapiens)1624291 PMID:31130282RGDPMID:31130282
Rras2RatGTPase activity enablesIEAUniProtKB:P62070 and ensembl:ENSP000002561961600115GO_REF:0000107EnsemblGO_REF:0000107
Rras2RatGTPase activity enablesIEAInterPro:IPR0018061600115GO_REF:0000002InterProGO_REF:0000002
Rras2RatGTPase activity enablesIBACGD:CAL0000181665 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Rras2Ratprotein binding enablesISORRAS2 (Homo sapiens)1624291UniProtKB:P10398 more ...RGDPMID:12620389 more ...
Rras2Ratprotein binding enablesISORras2 (Mus musculus)1624291PR:Q03385 PMID:11788587RGDPMID:11788587
1 to 10 of 10 rows

Imported Annotations - KEGG (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Rras2Ratmitogen activated protein kinase signaling pathway   IEA 6907045 KEGGrno:04010

#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:11788587   PMID:14724565   PMID:16210410   PMID:19056867   PMID:21085126   PMID:21423176   PMID:35352799  



Rras2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81177,668,143 - 177,737,551 (-)NCBIGRCr8
mRatBN7.21168,233,693 - 168,303,111 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1168,233,693 - 168,303,111 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1176,562,741 - 176,632,090 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01183,748,814 - 183,818,172 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01176,462,863 - 176,532,658 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01178,940,515 - 179,010,257 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1178,940,516 - 179,010,257 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01185,908,263 - 185,978,450 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41172,026,262 - 172,097,710 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11172,162,371 - 172,233,819 (-)NCBI
Celera1166,086,473 - 166,155,650 (-)NCBICelera
Cytogenetic Map1q33NCBI
RRAS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381114,277,920 - 14,364,506 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1114,277,922 - 14,364,506 (-)EnsemblGRCh38hg38GRCh38
GRCh371114,299,466 - 14,386,052 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361114,256,042 - 14,337,305 (-)NCBINCBI36Build 36hg18NCBI36
Build 341114,256,871 - 14,337,289NCBI
Celera1114,424,875 - 14,511,140 (-)NCBICelera
Cytogenetic Map11p15.2NCBI
HuRef1113,981,134 - 14,067,065 (-)NCBIHuRef
CHM1_11114,298,377 - 14,384,667 (-)NCBICHM1_1
T2T-CHM13v2.01114,373,520 - 14,459,786 (-)NCBIT2T-CHM13v2.0
Rras2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397113,646,017 - 113,717,016 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7113,646,017 - 113,717,016 (-)EnsemblGRCm39 Ensembl
GRCm387114,046,782 - 114,117,781 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7114,046,782 - 114,117,781 (-)EnsemblGRCm38mm10GRCm38
MGSCv377121,190,296 - 121,261,295 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367113,837,969 - 113,908,962 (-)NCBIMGSCv36mm8
Celera7114,009,446 - 114,081,527 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map759.29NCBI
Rras2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541429,481,343 - 29,493,070 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541429,482,502 - 29,546,102 (-)NCBIChiLan1.0ChiLan1.0
RRAS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2916,659,725 - 16,740,763 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11116,622,081 - 16,703,102 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01114,381,173 - 14,462,192 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11114,073,679 - 14,154,027 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1114,073,679 - 14,159,611 (-)Ensemblpanpan1.1panPan2
RRAS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12137,037,576 - 37,119,733 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2137,038,334 - 37,112,662 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2136,540,855 - 36,621,893 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02137,927,178 - 38,008,648 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2137,928,606 - 38,008,632 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12137,178,474 - 37,259,232 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02137,363,683 - 37,444,503 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02137,644,316 - 37,725,950 (-)NCBIUU_Cfam_GSD_1.0
Rras2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494748,379,460 - 48,395,186 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365284,413,436 - 4,427,741 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365284,413,436 - 4,429,166 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RRAS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1244,890,129 - 44,961,003 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RRAS2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1150,527,669 - 50,607,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl150,527,699 - 50,607,871 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666038148,071,811 - 148,151,429 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rras2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247666,180,822 - 6,244,692 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247666,179,507 - 6,244,722 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Rras2
458 total Variants

Predicted Target Of
Summary Value
Count of predictions:677
Count of miRNA genes:294
Interacting mature miRNAs:361
Transcripts:ENSRNOT00000017199
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 74 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat

1 to 10 of 74 rows
D1Rat243  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81177,712,466 - 177,712,705 (+)Marker Load Pipeline
mRatBN7.21168,278,025 - 168,278,264 (+)MAPPERmRatBN7.2
Rnor_6.01178,985,175 - 178,985,413NCBIRnor6.0
Rnor_5.01185,953,368 - 185,953,606UniSTSRnor5.0
RGSC_v3.41172,072,625 - 172,072,864RGDRGSC3.4
RGSC_v3.41172,072,626 - 172,072,864UniSTSRGSC3.4
RGSC_v3.11172,208,735 - 172,208,973RGD
Celera1166,130,565 - 166,130,803UniSTS
RH 3.4 Map11316.29RGD
RH 3.4 Map11316.29UniSTS
RH 2.0 Map1868.3RGD
SHRSP x BN Map184.65RGD
FHH x ACI Map181.06RGD
Cytogenetic Map1q34UniSTS
C86394  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21168,233,945 - 168,234,027 (+)MAPPERmRatBN7.2
Rnor_6.01178,940,768 - 178,940,849NCBIRnor6.0
Rnor_5.01185,908,516 - 185,908,597UniSTSRnor5.0
RGSC_v3.41172,026,515 - 172,026,596UniSTSRGSC3.4
Celera1166,086,726 - 166,086,807UniSTS
Cytogenetic Map1q34UniSTS
PMC140962P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21045,916,922 - 45,917,137 (+)MAPPERmRatBN7.2
mRatBN7.21168,234,719 - 168,234,933 (+)MAPPERmRatBN7.2
Rnor_6.01178,941,542 - 178,941,755NCBIRnor6.0
Rnor_6.01047,514,096 - 47,514,310NCBIRnor6.0
Rnor_5.01047,288,934 - 47,289,148UniSTSRnor5.0
Rnor_5.01185,909,290 - 185,909,503UniSTSRnor5.0
RGSC_v3.41172,027,289 - 172,027,502UniSTSRGSC3.4
RGSC_v3.41047,389,121 - 47,389,335UniSTSRGSC3.4
Celera1045,170,319 - 45,170,533UniSTS
Celera1166,087,500 - 166,087,713UniSTS
Cytogenetic Map1q34UniSTS
Cytogenetic Map10q22UniSTS
RH134521  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21168,234,569 - 168,234,749 (+)MAPPERmRatBN7.2
Rnor_6.01178,941,392 - 178,941,571NCBIRnor6.0
Rnor_5.01185,909,140 - 185,909,319UniSTSRnor5.0
RGSC_v3.41172,027,139 - 172,027,318UniSTSRGSC3.4
Celera1166,087,350 - 166,087,529UniSTS
RH 3.4 Map11317.9UniSTS
Cytogenetic Map1q34UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000017199   ⟹   ENSRNOP00000017199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1168,233,694 - 168,303,111 (-)Ensembl
Rnor_6.0 Ensembl1178,940,516 - 179,010,257 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087771   ⟹   ENSRNOP00000073247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1178,941,894 - 178,955,352 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096467   ⟹   ENSRNOP00000081051
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1168,233,693 - 168,251,234 (-)Ensembl
RefSeq Acc Id: NM_001013434   ⟹   NP_001013452
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81177,668,143 - 177,737,551 (-)NCBI
mRatBN7.21168,233,693 - 168,303,111 (-)NCBI
Rnor_6.01178,940,515 - 179,010,257 (-)NCBI
Rnor_5.01185,908,263 - 185,978,450 (-)NCBI
RGSC_v3.41172,026,262 - 172,097,710 (-)RGD
Celera1166,086,473 - 166,155,650 (-)RGD
Sequence:
Protein RefSeqs NP_001013452 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91333 (Get FASTA)   NCBI Sequence Viewer  
  EDM17786 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000017199
  ENSRNOP00000017199.3
  ENSRNOP00000081051.1
RefSeq Acc Id: NP_001013452   ⟸   NM_001013434
- UniProtKB: Q5BJU0 (UniProtKB/TrEMBL),   F7ESH4 (UniProtKB/TrEMBL),   A0A8I6G5F9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073247   ⟸   ENSRNOT00000087771
Ensembl Acc Id: ENSRNOP00000017199   ⟸   ENSRNOT00000017199
Ensembl Acc Id: ENSRNOP00000081051   ⟸   ENSRNOT00000096467

Name Modeler Protein Id AA Range Protein Structure
AF-Q5BJU0-F1-model_v2 AlphaFold Q5BJU0 1-204 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13690327
Promoter ID:EPDNEW_R852
Type:multiple initiation site
Name:Rras2_1
Description:RAS related 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01179,010,272 - 179,010,332EPDNEW


1 to 30 of 30 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-57744 BioCyc
Ensembl Genes ENSRNOG00000012258 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017199 ENTREZGENE
  ENSRNOT00000017199.6 UniProtKB/TrEMBL
  ENSRNOT00000096467.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7314509 IMAGE-MGC_LOAD
InterPro P-loop_NTPase UniProtKB/TrEMBL
  Ras_GTPase UniProtKB/TrEMBL
  Ras_small_GTPase UniProtKB/TrEMBL
  Small_GTP-bd_dom UniProtKB/TrEMBL
KEGG Report rno:365355 UniProtKB/TrEMBL
MGC_CLONE MGC:109327 IMAGE-MGC_LOAD
NCBI Gene 365355 ENTREZGENE
PANTHER PTHR24070 UniProtKB/TrEMBL
Pfam Ras UniProtKB/TrEMBL
PhenoGen Rras2 PhenoGen
PRINTS RASTRNSFRMNG UniProtKB/TrEMBL
PROSITE RAB UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012258 RatGTEx
SMART RAB UniProtKB/TrEMBL
  RAN UniProtKB/TrEMBL
  RAS UniProtKB/TrEMBL
  RHO UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I6G5F9 ENTREZGENE, UniProtKB/TrEMBL
  F7ESH4 ENTREZGENE, UniProtKB/TrEMBL
  Q5BJU0 ENTREZGENE, UniProtKB/TrEMBL
1 to 30 of 30 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-16 Rras2  RAS related 2  Rras2  related RAS viral (r-ras) oncogene homolog 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Rras2  related RAS viral (r-ras) oncogene homolog 2  Rras2_predicted  related RAS viral (r-ras) oncogene homolog 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Rras2_predicted  related RAS viral (r-ras) oncogene homolog 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED