Gsto2 (glutathione S-transferase omega 2) - Rat Genome Database

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Gene: Gsto2 (glutathione S-transferase omega 2) Rattus norvegicus
Analyze
Symbol: Gsto2
Name: glutathione S-transferase omega 2
RGD ID: 1310764
Description: Predicted to enable glutathione dehydrogenase (ascorbate) activity; glutathione transferase activity; and identical protein binding activity. Predicted to be involved in several processes, including L-ascorbic acid metabolic process; cellular response to arsenic-containing substance; and glutathione metabolic process. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; and asthma. Orthologous to human GSTO2 (glutathione S-transferase omega 2); PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; glutathione synthase deficiency pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; all-trans-retinoic acid; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glutathione S-transferase omega 2-2; glutathione S-transferase omega-2; glutathione-dependent dehydroascorbate reductase; GSTO 2-2; GSTO-2; LOC103690044; LOC309465; MMA(V) reductase; monomethylarsonic acid reductase
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81256,673,376 - 256,695,154 (+)NCBIGRCr8
mRatBN7.21246,731,314 - 246,757,592 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1246,732,089 - 246,753,866 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1254,859,384 - 254,881,207 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01261,552,355 - 261,574,175 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01254,202,420 - 254,224,048 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01267,617,517 - 267,640,455 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1267,607,416 - 267,640,455 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1271,229,036 - 271,243,517 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01275,050,163 - 275,072,303 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01278,656,945 - 278,671,426 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41253,239,392 - 253,275,110 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11253,504,135 - 253,539,851 (+)NCBI
Celera1242,496,974 - 242,517,641 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease. Li YJ, etal., Hum Mol Genet 2003 Dec 15;12(24):3259-67. Epub 2003 Oct 21.
3. Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer's disease. Ozturk A, etal., Neurobiol Aging. 2005 Aug-Sep;26(8):1161-5. Epub 2004 Dec 18.
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GSTA1, GSTO1 and GSTO2 gene polymorphisms in Italian asthma patients. Polimanti R, etal., Clin Exp Pharmacol Physiol. 2010 Aug;37(8):870-2. Epub 2010 Mar 30.
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Glutathione S-transferase: genetics and role in toxicology. Strange RC, etal., Toxicol Lett 2000 Mar 15;112-113:357-63.
10. Glutathione S-transferase mu, omega, pi, and theta class variants and smoking in Parkinson's disease. Wahner AD, etal., Neurosci Lett. 2007 Feb 21;413(3):274-8. Epub 2006 Dec 27.
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:15970797   PMID:19056867   PMID:25416956  


Genomics

Comparative Map Data
Gsto2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81256,673,376 - 256,695,154 (+)NCBIGRCr8
mRatBN7.21246,731,314 - 246,757,592 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1246,732,089 - 246,753,866 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1254,859,384 - 254,881,207 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01261,552,355 - 261,574,175 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01254,202,420 - 254,224,048 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01267,617,517 - 267,640,455 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1267,607,416 - 267,640,455 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1271,229,036 - 271,243,517 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01275,050,163 - 275,072,303 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01278,656,945 - 278,671,426 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41253,239,392 - 253,275,110 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11253,504,135 - 253,539,851 (+)NCBI
Celera1242,496,974 - 242,517,641 (+)NCBICelera
Cytogenetic Map1q54NCBI
GSTO2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810104,269,184 - 104,304,950 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10104,268,873 - 104,304,950 (+)EnsemblGRCh38hg38GRCh38
GRCh3710106,028,942 - 106,064,708 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3610106,018,621 - 106,049,166 (+)NCBINCBI36Build 36hg18NCBI36
Celera1099,769,465 - 99,799,992 (+)NCBICelera
Cytogenetic Map10q25.1NCBI
HuRef1099,660,411 - 99,690,935 (+)NCBIHuRef
CHM1_110106,312,517 - 106,343,025 (+)NCBICHM1_1
T2T-CHM13v2.010105,157,320 - 105,193,113 (+)NCBIT2T-CHM13v2.0
Gsto2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391947,853,879 - 47,874,747 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1947,853,973 - 47,874,763 (+)EnsemblGRCm39 Ensembl
GRCm381947,865,438 - 47,886,308 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1947,865,534 - 47,886,324 (+)EnsemblGRCm38mm10GRCm38
MGSCv371947,940,284 - 47,960,795 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361947,919,114 - 47,939,616 (+)NCBIMGSCv36mm8
Celera1948,626,289 - 48,646,818 (+)NCBICelera
Cytogenetic Map19D1NCBI
cM Map1940.41NCBI
GSTO2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28116,153,709 - 116,185,499 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110116,159,053 - 116,190,832 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v010100,868,109 - 100,901,013 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110104,326,174 - 104,357,604 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10104,326,175 - 104,357,604 (+)Ensemblpanpan1.1panPan2
GSTO2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12816,580,250 - 16,604,977 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2816,586,777 - 16,604,976 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2816,752,960 - 16,777,367 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02817,058,781 - 17,083,140 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2817,064,468 - 17,083,139 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12816,606,330 - 16,630,694 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02816,635,026 - 16,659,336 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02816,773,733 - 16,798,027 (+)NCBIUU_Cfam_GSD_1.0
Gsto2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721330,304,171 - 30,322,114 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366001,907,517 - 1,925,235 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366001,907,396 - 1,925,256 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSTO2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14115,217,879 - 115,251,435 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114115,218,179 - 115,242,377 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214125,187,089 - 125,209,743 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GSTO2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1997,319,695 - 97,348,406 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl997,325,215 - 97,349,422 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604858,438,455 - 58,468,894 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Gsto2
202 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:181
Count of miRNA genes:110
Interacting mature miRNAs:113
Transcripts:ENSRNOT00000017186
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631669Iddm9Insulin dependent diabetes mellitus QTL 92.80.039blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1233190394258625266Rat
631690Scl5Serum cholesterol level QTL 52.1blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1236125214260522016Rat
731175Uae20Urinary albumin excretion QTL 203.50.0018urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1221264111259647894Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
631836Stl31Serum triglyceride level QTL 314.640.00000487blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1237147813260522016Rat
631837Niddm35Non-insulin dependent diabetes mellitus QTL 350.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1238699859259647894Rat
631843Bw116Body weight QTL 1164.10.016abdominal adipose amount (VT:1000220)abdominal fat pad weight (CMO:0000088)1224054293260122809Rat
1300108Rf8Renal function QTL 83.75renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)1228581588259647894Rat
10053715Scort24Serum corticosterone level QTL 242.130.0088blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1221414816260522016Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
1357399Bw45Body weight QTL 453.05body mass (VT:0001259)body mass index (BMI) (CMO:0000105)1206329708251329708Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
1358890Bp259Blood pressure QTL 2593.06arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1210702053260522016Rat
1581544Rf52Renal function QTL 520.05urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)1232156370259647894Rat
1598821Rf55Renal function QTL 556.3renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1218748008257976495Rat
1598839Rf56Renal function QTL 56renal blood flow trait (VT:2000006)ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239)1245907761257976495Rat
1600392Bw123Body weight QTL 1230.001body mass (VT:0001259)body weight (CMO:0000012)1223201027260522016Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
61327Eae7Experimental allergic encephalomyelitis QTL 75.6body mass (VT:0001259)change in body weight (CMO:0002045)1216255568260522016Rat
70211Niddm24Non-insulin dependent diabetes mellitus QTL 243.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1214647894259647894Rat
631215Stl8Serum triglyceride level QTL 89.270.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1225126575260522016Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
724533Rf51Renal function QTL 515.30.0002kidney plasma flow trait (VT:0005524)renal plasma flow (CMO:0001914)1218753816256448513Rat
724552Glom2Glomerulus QTL 23.30.0001kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)1222363780260522016Rat
2302040Pia35Pristane induced arthritis QTL 353.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1216255568260522016Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
631536Lnnr2Liver neoplastic nodule remodeling QTL 22.90.0005liver integrity trait (VT:0010547)liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705)1233948574260522016Rat
734769Niddm58Non-insulin dependent diabetes mellitus QTL 58body mass (VT:0001259)body weight (CMO:0000012)1224569538260122809Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
734768Niddm59Non-insulin dependent diabetes mellitus QTL 59body mass (VT:0001259)body weight (CMO:0000012)1213843987258843987Rat
1357404Bw42Body weight QTL 424.490.0001body mass (VT:0001259)body weight (CMO:0000012)1206329708251329708Rat
1549910Bw54Body weight QTL 540.05body mass (VT:0001259)body weight (CMO:0000012)1214647894259647894Rat
1600397Edcs4Endometrial carcinoma susceptibility QTL 42.2uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)1206081677251081677Rat
734767Niddm57Non-insulin dependent diabetes mellitus QTL 57body mass (VT:0001259)body weight (CMO:0000012)1224054293260122809Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
724538Kidm1Kidney mass QTL 13.2kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1213707201252085212Rat

Markers in Region
BF387299  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21246,753,680 - 246,753,860 (+)MAPPERmRatBN7.2
Rnor_6.01271,243,329 - 271,243,508NCBIRnor6.0
Rnor_6.01267,640,267 - 267,640,446NCBIRnor6.0
Rnor_5.01278,671,238 - 278,671,417UniSTSRnor5.0
Rnor_5.01275,072,115 - 275,072,294UniSTSRnor5.0
RGSC_v3.41253,274,922 - 253,275,101UniSTSRGSC3.4
Celera1242,517,453 - 242,517,632UniSTS
RH 3.4 Map11623.8UniSTS
Cytogenetic Map1q54UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7
Low 2 19 18 6 8 6 72 30 32 11
Below cutoff 1 24 39 35 11 35 8 11 2 5 2 8

Sequence


RefSeq Acc Id: ENSRNOT00000017186   ⟹   ENSRNOP00000017186
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1246,732,089 - 246,753,866 (+)Ensembl
Rnor_6.0 Ensembl1267,618,248 - 267,640,455 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000064023   ⟹   ENSRNOP00000060669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1246,732,089 - 246,753,866 (+)Ensembl
Rnor_6.0 Ensembl1271,229,036 - 271,243,517 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076251   ⟹   ENSRNOP00000068075
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1267,618,565 - 267,627,827 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000076751
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1267,618,581 - 267,638,938 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087894   ⟹   ENSRNOP00000068891
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1267,607,416 - 267,640,402 (+)Ensembl
RefSeq Acc Id: NM_001012071   ⟹   NP_001012071
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81256,673,376 - 256,695,154 (+)NCBI
mRatBN7.21246,732,089 - 246,753,869 (+)NCBI
Rnor_6.01267,618,248 - 267,640,455 (+)NCBI
Rnor_5.01278,656,945 - 278,671,426 (+)NCBI
RGSC_v3.41253,239,392 - 253,275,110 (+)RGD
Celera1242,496,974 - 242,517,641 (+)RGD
Sequence:
RefSeq Acc Id: NM_001419742   ⟹   NP_001406671
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81256,673,648 - 256,695,154 (+)NCBI
mRatBN7.21246,732,361 - 246,753,869 (+)NCBI
RefSeq Acc Id: XM_006231590   ⟹   XP_006231652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81256,673,613 - 256,695,154 (+)NCBI
mRatBN7.21246,732,325 - 246,757,592 (+)NCBI
Rnor_6.01267,618,484 - 267,640,455 (+)NCBI
Rnor_5.01275,050,163 - 275,072,303 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231592   ⟹   XP_006231654
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81256,673,427 - 256,695,154 (+)NCBI
mRatBN7.21246,731,314 - 246,757,592 (+)NCBI
Rnor_6.01267,617,517 - 267,640,455 (+)NCBI
Rnor_5.01275,050,163 - 275,072,303 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001012071   ⟸   NM_001012071
- UniProtKB: Q6AXV9 (UniProtKB/Swiss-Prot),   B6DYQ6 (UniProtKB/TrEMBL),   A0A8L2Q9F9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231654   ⟸   XM_006231592
- Peptide Label: isoform X1
- UniProtKB: Q6AXV9 (UniProtKB/Swiss-Prot),   B6DYQ6 (UniProtKB/TrEMBL),   A0A8L2Q9F9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006231652   ⟸   XM_006231590
- Peptide Label: isoform X1
- UniProtKB: Q6AXV9 (UniProtKB/Swiss-Prot),   B6DYQ6 (UniProtKB/TrEMBL),   A0A8L2Q9F9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068891   ⟸   ENSRNOT00000087894
RefSeq Acc Id: ENSRNOP00000017186   ⟸   ENSRNOT00000017186
RefSeq Acc Id: ENSRNOP00000068075   ⟸   ENSRNOT00000076251
RefSeq Acc Id: ENSRNOP00000060669   ⟸   ENSRNOT00000064023
RefSeq Acc Id: NP_001406671   ⟸   NM_001419742
- UniProtKB: Q6AXV9 (UniProtKB/Swiss-Prot),   B6DYQ6 (UniProtKB/TrEMBL),   A0A8L2Q9F9 (UniProtKB/TrEMBL)
Protein Domains
GST C-terminal   GST N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AXV9-F1-model_v2 AlphaFold Q6AXV9 1-248 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690983
Promoter ID:EPDNEW_R1507
Type:initiation region
Name:Gsto2_1
Description:glutathione S-transferase omega 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01267,618,506 - 267,618,566EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310764 AgrOrtholog
BioCyc Gene G2FUF-55462 BioCyc
Ensembl Genes ENSRNOG00000012801 Ensembl
  ENSRNOG00000049964 Ensembl
  ENSRNOG00000069697 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00060019077 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017186 ENTREZGENE
  ENSRNOT00000017186.7 UniProtKB/TrEMBL
  ENSRNOT00000064023.4 UniProtKB/TrEMBL
  ENSRNOT00060033012 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.1050.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutaredoxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7134485 IMAGE-MGC_LOAD
InterPro Glutathione-S-Trfase_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glutathione_S-Trfase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_C UniProtKB/TrEMBL
  GST_omega UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:309465 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:94431 IMAGE-MGC_LOAD
NCBI Gene 309465 ENTREZGENE
PANTHER GLUTATHIONE S-TRANSFERASE OMEGA-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR43968 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam GST_C_3 UniProtKB/TrEMBL
  GST_N_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gsto2 PhenoGen
PRINTS GSTRNSFRASEO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GST_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GST_NTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012801 RatGTEx
  ENSRNOG00000049964 RatGTEx
  ENSRNOG00000069697 RatGTEx
  ENSRNOG00060019077 RatGTEx
Superfamily-SCOP SSF47616 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2Q9F9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QUB5_RAT UniProtKB/TrEMBL
  B6DYQ6 ENTREZGENE, UniProtKB/TrEMBL
  GSTO2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Gsto2  glutathione S-transferase omega 2  LOC103690044  glutathione S-transferase omega-2  Data merged from RGD:9449876 737654 PROVISIONAL
2014-08-25 LOC103690044  glutathione S-transferase omega-2      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Gsto2  glutathione S-transferase omega 2  Gsto2_predicted  glutathione S-transferase omega 2 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Gsto2_predicted  glutathione S-transferase omega 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED