Usp49 (ubiquitin specific peptidase 49) - Rat Genome Database

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Gene: Usp49 (ubiquitin specific peptidase 49) Rattus norvegicus
Analyze
Symbol: Usp49
Name: ubiquitin specific peptidase 49
RGD ID: 1310513
Description: Predicted to enable histone binding activity and peptidase activity. Predicted to be involved in mRNA splicing, via spliceosome; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and protein deubiquitination. Predicted to be active in cytoplasm. Orthologous to human USP49 (ubiquitin specific peptidase 49); INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC316211; RGD1310513; similar to hypothetical protein MGC20741; ubiquitin carboxyl-terminal hydrolase 49; ubiquitin thioesterase 49
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8920,803,177 - 20,867,681 (-)NCBIGRCr8
mRatBN7.2913,305,640 - 13,366,132 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl913,308,178 - 13,366,132 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx921,888,201 - 21,945,900 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0926,952,281 - 27,010,031 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0925,251,607 - 25,309,304 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0915,314,875 - 15,375,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl915,317,413 - 15,375,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0914,239,085 - 14,299,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.498,774,333 - 8,832,285 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.198,778,351 - 8,786,793 (-)NCBI
Celera911,060,638 - 11,117,551 (-)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp49Ratinfantile Refsum disease  ISOUSP49 (Homo sapiens)8554872ClinVar Annotator: match by term: ADRENOLEUKODYSTROPHY and AUTOSOMAL NEONATALClinVarPMID:19877282 more ...
Usp49RatZellweger syndrome  ISOUSP49 (Homo sapiens)8554872ClinVar Annotator: match by term: Peroxisome biogenesis disorders and Zellweger syndrome spectrumClinVarPMID:19877282 more ...

1 to 20 of 66 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp49Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of USP49 mRNA]CTDPMID:31150632
Usp49Rat1,2-dimethylhydrazine decreases expressionISOUsp49 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of USP49 mRNACTDPMID:22206623
Usp49Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOUsp49 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Usp49Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOUsp49 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Usp49Rat2-hydroxypropanoic acid increases expressionISOUSP49 (Homo sapiens)6480464Lactic Acid results in increased expression of USP49 mRNACTDPMID:30851411
Usp49Rat4,4'-sulfonyldiphenol decreases expressionISOUsp49 (Mus musculus)6480464bisphenol S results in decreased expression of USP49 mRNACTDPMID:39298647
Usp49Rat4,4'-sulfonyldiphenol affects methylationISOUsp49 (Mus musculus)6480464bisphenol S affects the methylation of USP49 geneCTDPMID:31683443
Usp49Rat4,4'-sulfonyldiphenol decreases methylationISOUsp49 (Mus musculus)6480464bisphenol S results in decreased methylation of USP49 exonCTDPMID:33297965
Usp49Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of USP49 mRNACTDPMID:24780913 and PMID:25825206
Usp49Ratall-trans-retinoic acid decreases expressionISOUSP49 (Homo sapiens)6480464Tretinoin results in decreased expression of USP49 mRNACTDPMID:21934132
Usp49Rataristolochic acid A increases expressionISOUSP49 (Homo sapiens)6480464aristolochic acid I results in increased expression of USP49 mRNACTDPMID:33212167
Usp49Ratbeta-lapachone decreases expressionISOUSP49 (Homo sapiens)6480464beta-lapachone results in decreased expression of USP49 mRNACTDPMID:38218311
Usp49Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of USP49 mRNACTDPMID:25181051
Usp49Ratbisphenol A decreases expressionISOUsp49 (Mus musculus)6480464bisphenol A results in decreased expression of USP49 mRNACTDPMID:33221593
Usp49Ratbromobenzene increases expressionEXP 6480464bromobenzene results in increased expression of USP49 mRNACTDPMID:32479839
Usp49Ratcadmium atom multiple interactionsISOUSP49 (Homo sapiens)6480464[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of USP49 mRNACTDPMID:35301059
Usp49Ratcadmium dichloride increases expressionISOUSP49 (Homo sapiens)6480464Cadmium Chloride results in increased expression of USP49 mRNACTDPMID:38568856
Usp49Ratcadmium dichloride multiple interactionsISOUSP49 (Homo sapiens)6480464[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of USP49 mRNACTDPMID:35301059
Usp49Ratchlorpyrifos decreases expressionISOUsp49 (Mus musculus)6480464Chlorpyrifos results in decreased expression of USP49 mRNACTDPMID:37019170
Usp49Ratcopper atom multiple interactionsISOUSP49 (Homo sapiens)6480464[NSC 689534 binds to Copper] which results in increased expression of USP49 mRNACTDPMID:20971185

1 to 20 of 66 rows

Biological Process
1 to 9 of 9 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp49Ratchromatin remodeling involved_inIEAGO:01409361600115GO_REF:0000108GOCGO_REF:0000108
Usp49RatmRNA splicing, via spliceosome involved_inISOUSP49 (Homo sapiens)1624291 PMID:23824326RGDPMID:23824326
Usp49RatmRNA splicing, via spliceosome involved_inIEAUniProtKB:Q70CQ1 and ensembl:ENSP000005072391600115GO_REF:0000107EnsemblGO_REF:0000107
Usp49Ratnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_inISOUSP49 (Homo sapiens)1624291 PMID:28363942RGDPMID:28363942
Usp49Ratnegative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_inIEAUniProtKB:Q70CQ1 and ensembl:ENSP000005072391600115GO_REF:0000107EnsemblGO_REF:0000107
Usp49Ratprotein deubiquitination involved_inISOUSP49 (Homo sapiens)1624291 PMID:28363942RGDPMID:28363942
Usp49Ratprotein deubiquitination involved_inIEAUniProtKB:Q70CQ1 and ensembl:ENSP000005072391600115GO_REF:0000107EnsemblGO_REF:0000107
Usp49Ratprotein deubiquitination involved_inIEAInterPro:IPR0013941600115GO_REF:0000002InterProGO_REF:0000002
Usp49Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
1 to 9 of 9 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp49Ratcytoplasm is_active_inIBAPANTHER:PTN002363655 and UniProtKB:Q9Y6I41600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function
1 to 19 of 19 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp49Ratcysteine-type deubiquitinase activity enablesIEAUniRule:UR0008807561600115GO_REF:0000104UniProtGO_REF:0000104
Usp49Ratcysteine-type deubiquitinase activity enablesIEAInterPro:IPR001394 and InterPro:IPR0182001600115GO_REF:0000002InterProGO_REF:0000002
Usp49Ratcysteine-type deubiquitinase activity enablesIEAUniProtKB:Q70CQ1 and ensembl:ENSP000005072391600115GO_REF:0000107EnsemblGO_REF:0000107
Usp49Ratcysteine-type deubiquitinase activity enablesISOUSP49 (Homo sapiens)1624291 PMID:14715245 more ...RGDPMID:14715245 more ...
Usp49Ratcysteine-type deubiquitinase activity enablesIEAEC:3.4.19.121600115GO_REF:0000003UniProtGO_REF:0000003
Usp49Ratcysteine-type endopeptidase activity enablesISOUSP49 (Homo sapiens)1624291 PMID:23824326RGDPMID:23824326
Usp49Ratcysteine-type endopeptidase activity enablesIEAUniProtKB:Q70CQ1 and ensembl:ENSP000005072391600115GO_REF:0000107EnsemblGO_REF:0000107
Usp49Ratcysteine-type peptidase activity enablesIEAUniProtKB-KW:KW-07881600115GO_REF:0000043UniProtGO_REF:0000043
Usp49Rathistone binding enablesISOUSP49 (Homo sapiens)1624291 PMID:23824326RGDPMID:23824326
Usp49Rathistone binding enablesIEAUniProtKB:Q70CQ1 and ensembl:ENSP000005072391600115GO_REF:0000107EnsemblGO_REF:0000107
Usp49Rathistone H2B deubiquitinase activity enablesIEAUniProtKB:Q70CQ1 and ensembl:ENSP000005072391600115GO_REF:0000107EnsemblGO_REF:0000107
Usp49Rathistone H2B deubiquitinase activity enablesISOUSP49 (Homo sapiens)1624291 PMID:23824326RGDPMID:23824326
Usp49Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Usp49Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Usp49Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Usp49Ratprotein binding enablesISOUSP49 (Homo sapiens)1624291UniProtKB:P62195 more ...RGDPMID:19615732 more ...
Usp49Ratprotein binding enablesISOUSP49 (Homo sapiens) and UniProtKB:Q70CQ1-21624291UniProtKB:P43490 more ...RGDPMID:32296183
Usp49Ratzinc ion binding enablesIEAInterPro:IPR0016071600115GO_REF:0000002InterProGO_REF:0000002
Usp49Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
1 to 19 of 19 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:14715245   PMID:15632090   PMID:23824326  



Usp49
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8920,803,177 - 20,867,681 (-)NCBIGRCr8
mRatBN7.2913,305,640 - 13,366,132 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl913,308,178 - 13,366,132 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx921,888,201 - 21,945,900 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0926,952,281 - 27,010,031 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0925,251,607 - 25,309,304 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0915,314,875 - 15,375,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl915,317,413 - 15,375,365 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0914,239,085 - 14,299,667 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.498,774,333 - 8,832,285 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.198,778,351 - 8,786,793 (-)NCBI
Celera911,060,638 - 11,117,551 (-)NCBICelera
Cytogenetic Map9q12NCBI
USP49
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38641,789,896 - 41,895,375 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl641,789,896 - 41,895,375 (-)EnsemblGRCh38hg38GRCh38
GRCh37641,757,634 - 41,863,113 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36641,873,361 - 41,971,077 (-)NCBINCBI36Build 36hg18NCBI36
Celera643,318,714 - 43,416,439 (-)NCBICelera
Cytogenetic Map6p21.1NCBI
HuRef641,484,106 - 41,581,878 (-)NCBIHuRef
CHM1_1641,768,743 - 41,866,405 (-)NCBICHM1_1
T2T-CHM13v2.0641,618,461 - 41,723,935 (-)NCBIT2T-CHM13v2.0
Usp49
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391747,941,615 - 47,997,664 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1747,941,615 - 47,997,663 (+)EnsemblGRCm39 Ensembl
GRCm381747,630,690 - 47,686,739 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1747,630,690 - 47,686,738 (+)EnsemblGRCm38mm10GRCm38
MGSCv371747,767,639 - 47,821,016 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361747,093,881 - 47,147,258 (+)NCBIMGSCv36mm8
Celera1751,067,647 - 51,120,972 (+)NCBICelera
Cytogenetic Map17CNCBI
cM Map1723.72NCBI
Usp49
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554378,191,236 - 8,198,809 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554378,187,118 - 8,237,910 (-)NCBIChiLan1.0ChiLan1.0
USP49
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2556,282,907 - 56,389,693 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1652,152,885 - 52,256,921 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0641,375,083 - 41,479,143 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1642,678,680 - 42,781,748 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl642,683,149 - 42,695,707 (-)Ensemblpanpan1.1panPan2
USP49
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11210,474,873 - 10,556,900 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1210,479,733 - 10,577,918 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1210,504,358 - 10,589,769 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01210,955,129 - 11,041,174 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1210,955,164 - 11,051,627 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11210,485,701 - 10,567,699 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01210,569,381 - 10,654,952 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01210,663,097 - 10,748,867 (-)NCBIUU_Cfam_GSD_1.0
Usp49
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494645,957,669 - 46,049,495 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647617,991,688 - 18,000,794 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647617,946,875 - 18,002,081 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP49
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl736,981,383 - 37,052,568 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1736,978,291 - 37,054,027 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2742,393,547 - 42,458,617 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP49
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11730,265,322 - 30,373,547 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1730,356,698 - 30,366,940 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604441,783,918 - 41,895,090 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp49
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475417,266,561 - 17,274,926 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475417,226,723 - 17,281,206 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Usp49
298 total Variants

Predicted Target Of
Summary Value
Count of predictions:656
Count of miRNA genes:293
Interacting mature miRNAs:357
Transcripts:ENSRNOT00000018550
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 19 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
10054141Gmadr4Adrenal mass QTL 42.450.0074adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)9114209783Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
1578675Bss17Bone structure and strength QTL 173.8femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)9336865213533896Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat

1 to 10 of 19 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000018550   ⟹   ENSRNOP00000018550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl913,308,178 - 13,366,132 (-)Ensembl
Rnor_6.0 Ensembl915,317,413 - 15,375,365 (-)Ensembl
RefSeq Acc Id: NM_001136470   ⟹   NP_001129942
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,805,715 - 20,863,667 (-)NCBI
mRatBN7.2913,308,178 - 13,366,132 (-)NCBI
Rnor_6.0915,317,413 - 15,375,365 (-)NCBI
Rnor_5.0914,239,085 - 14,299,667 (-)NCBI
RGSC_v3.498,774,333 - 8,832,285 (-)RGD
Celera911,060,638 - 11,117,551 (-)RGD
Sequence:
RefSeq Acc Id: XM_006244435   ⟹   XP_006244497
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,803,177 - 20,826,448 (-)NCBI
mRatBN7.2913,305,640 - 13,323,918 (-)NCBI
Rnor_6.0915,314,875 - 15,333,131 (-)NCBI
Rnor_5.0914,239,085 - 14,299,667 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596410   ⟹   XP_017451899
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,803,177 - 20,863,303 (-)NCBI
mRatBN7.2913,305,640 - 13,365,484 (-)NCBI
Rnor_6.0915,314,875 - 15,374,664 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596411   ⟹   XP_017451900
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,803,177 - 20,862,630 (-)NCBI
mRatBN7.2913,305,640 - 13,365,041 (-)NCBI
Rnor_6.0915,314,875 - 15,374,185 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083485   ⟹   XP_038939413
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,803,177 - 20,862,751 (-)NCBI
mRatBN7.2913,305,640 - 13,365,194 (-)NCBI
RefSeq Acc Id: XM_063267083   ⟹   XP_063123153
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8920,803,177 - 20,867,681 (-)NCBI
1 to 9 of 9 rows
Protein RefSeqs NP_001129942 (Get FASTA)   NCBI Sequence Viewer  
  XP_006244497 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451899 (Get FASTA)   NCBI Sequence Viewer  
  XP_017451900 (Get FASTA)   NCBI Sequence Viewer  
  XP_038939413 (Get FASTA)   NCBI Sequence Viewer  
  XP_063123153 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM18893 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018550
  ENSRNOP00000018550.5
1 to 9 of 9 rows
RefSeq Acc Id: NP_001129942   ⟸   NM_001136470
- UniProtKB: D3ZJ49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006244497   ⟸   XM_006244435
- Peptide Label: isoform X1
- UniProtKB: D3ZJ49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451899   ⟸   XM_017596410
- Peptide Label: isoform X1
- UniProtKB: D3ZJ49 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451900   ⟸   XM_017596411
- Peptide Label: isoform X1
- UniProtKB: D3ZJ49 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018550   ⟸   ENSRNOT00000018550
UBP-type   USP

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZJ49-F1-model_v2 AlphaFold D3ZJ49 1-685 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-28276 BioCyc
Ensembl Genes ENSRNOG00000013866 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000018550 ENTREZGENE
  ENSRNOT00000018550.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain_like_cys_pep_sf UniProtKB/TrEMBL
  Pept_C19ubi-hydrolase_C_CS UniProtKB/TrEMBL
  Peptidase_C19 UniProtKB/TrEMBL
  Ub_carboxyl-term_hydrolase UniProtKB/TrEMBL
  UCH/PAN2 UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
KEGG Report rno:316211 UniProtKB/TrEMBL
NCBI Gene 316211 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 49 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
PhenoGen Usp49 PhenoGen
PROSITE UCH_2_1 UniProtKB/TrEMBL
  UCH_2_2 UniProtKB/TrEMBL
  UCH_2_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000013866 RatGTEx
SMART ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt D3ZJ49 ENTREZGENE, UniProtKB/TrEMBL
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Usp49  ubiquitin specific peptidase 49   Usp49_predicted  ubiquitin specific peptidase 49 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Usp49_predicted  ubiquitin specific peptidase 49 (predicted)  RGD1310513_predicted  similar to hypothetical protein MGC20741 (predicted)  Symbol and Name updated 1299863 APPROVED
2005-01-20 RGD1310513_predicted  similar to hypothetical protein MGC20741 (predicted)  LOC316211_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC316211_predicted  similar to hypothetical protein MGC20741 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL