Prkd3 (protein kinase D3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Prkd3 (protein kinase D3) Rattus norvegicus
Analyze
Symbol: Prkd3
Name: protein kinase D3
RGD ID: 1310236
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be active in cytosol. Orthologous to human PRKD3 (protein kinase D3); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313834; Prkcn; protein kinase C, nu; serine/threonine-protein kinase D3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8621,784,665 - 21,860,600 (+)NCBIGRCr8
mRatBN7.2616,032,507 - 16,108,444 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,032,585 - 16,108,443 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx616,355,379 - 16,423,921 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0616,677,588 - 16,746,130 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,157,980 - 16,226,554 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.061,546,018 - 1,622,232 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl61,548,415 - 1,622,196 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.061,536,128 - 1,611,876 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.461,727,315 - 1,796,290 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.161,751,738 - 1,764,473 (-)NCBI
Celera615,704,621 - 15,773,170 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
all-trans-retinoic acid  (ISO)
amphetamine  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chenodeoxycholic acid  (ISO)
chlorpyrifos  (EXP)
ciguatoxin CTX1B  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
decabromodiphenyl ether  (EXP)
deoxycholic acid  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
diclofenac  (ISO)
dicrotophos  (ISO)
diquat  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (EXP,ISO)
fipronil  (EXP)
flutamide  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hexadecanoic acid  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
microcystin-LR  (ISO)
N-nitrosodiethylamine  (EXP)
oxaliplatin  (EXP)
ozone  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP,ISO)
phlorizin  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
rimonabant  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP)
sunitinib  (ISO)
Sunset Yellow FCF  (ISO)
tamoxifen  (ISO)
tartrazine  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thimerosal  (ISO)
topotecan  (EXP)
tributylstannane  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,ISO)
membrane  (IEA)
nucleoplasm  (IEA,ISO)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Protein kinase D 3 is localized in vesicular structures and interacts with vesicle-associated membrane protein 2. Lu G, etal., Cell Signal. 2007 Apr;19(4):867-79. Epub 2006 Nov 16.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:21971046   PMID:22228765   PMID:27369082  


Genomics

Comparative Map Data
Prkd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8621,784,665 - 21,860,600 (+)NCBIGRCr8
mRatBN7.2616,032,507 - 16,108,444 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,032,585 - 16,108,443 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx616,355,379 - 16,423,921 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0616,677,588 - 16,746,130 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,157,980 - 16,226,554 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.061,546,018 - 1,622,232 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl61,548,415 - 1,622,196 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.061,536,128 - 1,611,876 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.461,727,315 - 1,796,290 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.161,751,738 - 1,764,473 (-)NCBI
Celera615,704,621 - 15,773,170 (+)NCBICelera
Cytogenetic Map6q12NCBI
PRKD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38237,250,502 - 37,324,833 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl237,250,502 - 37,324,833 (-)EnsemblGRCh38hg38GRCh38
GRCh37237,477,645 - 37,551,976 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36237,331,149 - 37,397,726 (-)NCBINCBI36Build 36hg18NCBI36
Build 34237,389,298 - 37,455,873NCBI
Celera237,318,598 - 37,385,166 (-)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef237,217,514 - 37,283,993 (-)NCBIHuRef
CHM1_1237,407,074 - 37,473,671 (-)NCBICHM1_1
T2T-CHM13v2.0237,257,518 - 37,331,821 (-)NCBIT2T-CHM13v2.0
Prkd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391779,256,834 - 79,328,245 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1779,256,834 - 79,328,245 (-)EnsemblGRCm39 Ensembl
GRCm381778,949,405 - 79,020,816 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,949,405 - 79,020,816 (-)EnsemblGRCm38mm10GRCm38
MGSCv371779,348,745 - 79,420,156 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361778,855,607 - 78,918,364 (-)NCBIMGSCv36mm8
Celera1783,270,085 - 83,333,948 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1749.69NCBI
Prkd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554415,051,079 - 5,112,799 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554415,051,079 - 5,112,791 (-)NCBIChiLan1.0ChiLan1.0
PRKD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21289,154,788 - 89,229,111 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A89,158,772 - 89,233,086 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A37,278,043 - 37,352,364 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A38,042,771 - 38,116,394 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A38,042,771 - 38,116,394 (-)Ensemblpanpan1.1panPan2
PRKD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11729,607,484 - 29,696,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1729,610,159 - 29,687,550 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1729,421,475 - 29,510,291 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01730,257,459 - 30,346,099 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1730,258,830 - 30,346,080 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11729,484,730 - 29,573,085 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01729,548,330 - 29,639,287 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01729,766,130 - 29,854,593 (-)NCBIUU_Cfam_GSD_1.0
Prkd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629242,313,646 - 42,382,136 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936663979,130 - 1,049,427 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936663979,136 - 1,047,633 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3102,842,229 - 102,941,329 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13102,840,666 - 102,949,128 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23109,438,196 - 109,546,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRKD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11470,064,678 - 70,142,790 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1470,072,330 - 70,140,176 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604541,805,140 - 41,881,579 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prkd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473818,853,963 - 18,927,122 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473818,851,165 - 18,927,177 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Prkd3
364 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:393
Count of miRNA genes:227
Interacting mature miRNAs:271
Transcripts:ENSRNOT00000007492
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6127574569Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6127574569Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6127574569Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6127574569Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6507449719988050Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6984331220338915Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6984331220338915Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat

Markers in Region
RH129843  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,108,080 - 16,108,260 (-)MAPPERmRatBN7.2
Rnor_6.061,546,202 - 1,546,381NCBIRnor6.0
Rnor_5.061,536,311 - 1,536,490UniSTSRnor5.0
RGSC_v3.461,727,498 - 1,727,677UniSTSRGSC3.4
Celera615,772,808 - 15,772,987UniSTS
Cytogenetic Map6q11UniSTS
RH131273  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,108,645 - 16,108,825 (-)MAPPERmRatBN7.2
Rnor_6.061,545,637 - 1,545,816NCBIRnor6.0
Rnor_5.061,535,746 - 1,535,925UniSTSRnor5.0
RGSC_v3.461,726,933 - 1,727,112UniSTSRGSC3.4
Celera615,773,373 - 15,773,552UniSTS
RH 3.4 Map632.8UniSTS
Cytogenetic Map6q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 36 57 41 19 41 8 8 57 30 35 11 8
Low 1 7 3 17 5 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007492   ⟹   ENSRNOP00000007491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,039,896 - 16,108,443 (+)Ensembl
Rnor_6.0 Ensembl61,548,415 - 1,622,196 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084528   ⟹   ENSRNOP00000069846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,071,139 - 16,083,871 (+)Ensembl
Rnor_6.0 Ensembl61,570,683 - 1,583,417 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095865   ⟹   ENSRNOP00000079860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,044,022 - 16,108,443 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101507   ⟹   ENSRNOP00000077406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,032,585 - 16,041,481 (+)Ensembl
RefSeq Acc Id: NM_001024263   ⟹   NP_001019434
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,792,052 - 21,860,600 (+)NCBI
mRatBN7.2616,039,896 - 16,108,443 (+)NCBI
Rnor_6.061,546,019 - 1,614,851 (-)NCBI
Rnor_5.061,536,128 - 1,611,876 (-)NCBI
RGSC_v3.461,727,315 - 1,796,290 (-)RGD
Celera615,704,621 - 15,773,170 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239629   ⟹   XP_006239691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,981 - 21,860,596 (+)NCBI
mRatBN7.2616,032,819 - 16,108,436 (+)NCBI
Rnor_6.061,547,742 - 1,621,961 (-)NCBI
Rnor_5.061,536,128 - 1,611,876 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239631   ⟹   XP_006239693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,806,802 - 21,860,596 (+)NCBI
mRatBN7.2616,063,839 - 16,108,444 (+)NCBI
Rnor_6.061,547,742 - 1,591,441 (-)NCBI
Rnor_5.061,536,128 - 1,611,876 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112128   ⟹   XP_038968056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,696 - 21,860,596 (+)NCBI
mRatBN7.2616,032,552 - 16,108,444 (+)NCBI
RefSeq Acc Id: XM_039112129   ⟹   XP_038968057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,665 - 21,860,596 (+)NCBI
mRatBN7.2616,032,507 - 16,108,444 (+)NCBI
RefSeq Acc Id: XM_063261804   ⟹   XP_063117874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,988 - 21,860,596 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001019434   ⟸   NM_001024263
- UniProtKB: D4A229 (UniProtKB/TrEMBL),   A0A8I6G5U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239691   ⟸   XM_006239629
- Peptide Label: isoform X1
- UniProtKB: D4A229 (UniProtKB/TrEMBL),   A0A8I6G5U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239693   ⟸   XM_006239631
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G5U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069846   ⟸   ENSRNOT00000084528
RefSeq Acc Id: ENSRNOP00000007491   ⟸   ENSRNOT00000007492
RefSeq Acc Id: XP_038968057   ⟸   XM_039112129
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G5U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968056   ⟸   XM_039112128
- Peptide Label: isoform X1
- UniProtKB: D4A229 (UniProtKB/TrEMBL),   A0A8I6G5U2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000077406   ⟸   ENSRNOT00000101507
RefSeq Acc Id: ENSRNOP00000079860   ⟸   ENSRNOT00000095865
RefSeq Acc Id: XP_063117874   ⟸   XM_063261804
- Peptide Label: isoform X1
- UniProtKB: D4A229 (UniProtKB/TrEMBL)
Protein Domains
PH   Phorbol-ester/DAG-type   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A229-F1-model_v2 AlphaFold D4A229 1-890 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694361
Promoter ID:EPDNEW_R4882
Type:initiation region
Name:Prkd3_2
Description:protein kinase D3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4883  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.061,583,411 - 1,583,471EPDNEW
RGD ID:13694358
Promoter ID:EPDNEW_R4883
Type:initiation region
Name:Prkd3_1
Description:protein kinase D3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4882  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.061,622,252 - 1,622,312EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310236 AgrOrtholog
BioCyc Gene G2FUF-38496 BioCyc
Ensembl Genes ENSRNOG00000005289 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007492 ENTREZGENE
  ENSRNOT00000007492.8 UniProtKB/TrEMBL
  ENSRNOT00000084528.2 UniProtKB/TrEMBL
  ENSRNOT00000095865.1 UniProtKB/TrEMBL
  ENSRNOT00000101507.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  DAG/PE_bd UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Prot_Kinase_C-like_PE/DAG_bd UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Protein_Kinase_C_mu-related UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:313834 UniProtKB/TrEMBL
NCBI Gene 313834 ENTREZGENE
PANTHER PKC_mu_like UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE D3 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PhenoGen Prkd3 PhenoGen
PIRSF PKC_mu_nu_D2 UniProtKB/TrEMBL
PRINTS DAGPEDOMAIN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005289 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
  SM00109 UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
  SSF57889 UniProtKB/TrEMBL
UniProt A0A8I5ZKA6_RAT UniProtKB/TrEMBL
  A0A8I6G5U2 ENTREZGENE, UniProtKB/TrEMBL
  D4A229 ENTREZGENE, UniProtKB/TrEMBL
  Q568X9_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-17 Prkd3  protein kinase D3  Prkcn  protein kinase C, nu  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Prkcn  protein kinase C, nu  Prkcn_predicted  protein kinase C, nu (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Prkcn_predicted  protein kinase C, nu (predicted)      Symbol and Name status set to approved 70820 APPROVED