Prkd3 (protein kinase D3) - Rat Genome Database

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Gene: Prkd3 (protein kinase D3) Rattus norvegicus
Analyze
Symbol: Prkd3
Name: protein kinase D3
RGD ID: 1310236
Description: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction and phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in ciliary basal body; nucleoplasm; and plasma membrane. Predicted to be active in cytosol. Orthologous to human PRKD3 (protein kinase D3); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC313834; Prkcn; protein kinase C, nu; serine/threonine-protein kinase D3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8621,784,665 - 21,860,600 (+)NCBIGRCr8
mRatBN7.2616,032,507 - 16,108,444 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,032,585 - 16,108,443 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx616,355,379 - 16,423,921 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0616,677,588 - 16,746,130 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,157,980 - 16,226,554 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.061,546,018 - 1,622,232 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl61,548,415 - 1,622,196 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.061,536,128 - 1,611,876 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.461,727,315 - 1,796,290 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.161,751,738 - 1,764,473 (-)NCBI
Celera615,704,621 - 15,773,170 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prkd3RatRASopathy  ISOPRKD3 (Homo sapiens)8554872ClinVar Annotator: match by term: RASopathyClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prkd3RatWeight Gain  ISOPRKD3 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:19030233

1 to 20 of 119 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prkd3Rat(+)-catechin multiple interactionsISOPRKD3 (Homo sapiens)6480464[Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of PRKD3 mRNACTDPMID:24763279
Prkd3Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRKD3 mRNA]CTDPMID:31150632
Prkd3Rat(1->4)-beta-D-glucan multiple interactionsISOPrkd3 (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of PRKD3 mRNACTDPMID:36331819
Prkd3Rat1,2-dimethylhydrazine multiple interactionsISOPrkd3 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of PRKD3 mRNACTDPMID:22206623
Prkd3Rat1,2-dimethylhydrazine affects expressionISOPrkd3 (Mus musculus)64804641 and 2-Dimethylhydrazine affects the expression of PRKD3 mRNACTDPMID:22206623
Prkd3Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of PRKD3 mRNACTDPMID:32145629
Prkd3Rat17beta-estradiol increases expressionISOPrkd3 (Mus musculus)6480464Estradiol results in increased expression of PRKD3 mRNACTDPMID:39298647
Prkd3Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of PRKD3 mRNACTDPMID:18796159 more ...
Prkd3Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOPrkd3 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of PRKD3 mRNACTDPMID:21570461
Prkd3Rat3-methylcholanthrene decreases expressionISOPrkd3 (Mus musculus)6480464Methylcholanthrene results in decreased expression of PRKD3 mRNACTDPMID:20713471
Prkd3Rat4,4'-diaminodiphenylmethane increases expressionISOPrkd3 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of PRKD3 mRNACTDPMID:18648102
Prkd3Rat4,4'-sulfonyldiphenol affects expressionISOPrkd3 (Mus musculus)6480464bisphenol S affects the expression of PRKD3 mRNACTDPMID:39298647
Prkd3Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of PRKD3 mRNACTDPMID:24780913
Prkd3Ratacrylamide decreases expressionEXP 6480464Acrylamide results in decreased expression of PRKD3 mRNACTDPMID:28959563
Prkd3Ratall-trans-retinoic acid decreases expressionISOPRKD3 (Homo sapiens)6480464Tretinoin results in decreased expression of PRKD3 mRNACTDPMID:33167477
Prkd3Ratamphetamine decreases expressionEXP 6480464Amphetamine results in decreased expression of PRKD3 mRNACTDPMID:30779732
Prkd3Rataristolochic acid A decreases expressionISOPRKD3 (Homo sapiens)6480464aristolochic acid I results in decreased expression of PRKD3 mRNACTDPMID:33212167
Prkd3RatAroclor 1254 decreases expressionISOPrkd3 (Mus musculus)6480464Chlorodiphenyl (54% Chlorine) results in decreased expression of PRKD3 mRNACTDPMID:23650126
Prkd3Ratarsane increases response to substanceISOPRKD3 (Homo sapiens)6480464PRKD3 mRNA results in increased susceptibility to ArsenicCTDPMID:17976673
Prkd3Ratarsane multiple interactionsISOPRKD3 (Homo sapiens)6480464[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of PRKD3 mRNACTDPMID:39836092

1 to 20 of 119 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prkd3Ratintracellular signal transduction involved_inIBAPANTHER:PTN001645384 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Prkd3Ratphospholipase C-activating G protein-coupled receptor signaling pathway involved_inIBAPANTHER:PTN001645384 and WB:WBGene000120191600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prkd3Ratciliary basal body located_inIEAUniProtKB:O94806 and ensembl:ENSP000002341791600115GO_REF:0000107EnsemblGO_REF:0000107
Prkd3Ratciliary basal body located_inISOPRKD3 (Homo sapiens) and UniProtKB:O94806-11624291 RGDGO_REF:0000052
Prkd3Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Prkd3Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Prkd3Ratcytosol located_inISOPRKD3 (Homo sapiens) and UniProtKB:O94806-11624291 RGDGO_REF:0000052
Prkd3Ratcytosol located_inIEAUniProtKB:O94806 and ensembl:ENSP000002341791600115GO_REF:0000107EnsemblGO_REF:0000107
Prkd3Ratcytosol is_active_inIBAMGI:99879 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Prkd3Ratmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043
Prkd3Ratmembrane located_inIEAUniProtKB-SubCell:SL-01621600115GO_REF:0000044UniProtGO_REF:0000044
Prkd3Ratnucleoplasm located_inIEAUniProtKB:O94806 and ensembl:ENSP000002341791600115GO_REF:0000107EnsemblGO_REF:0000107
Prkd3Ratnucleoplasm located_inISOPRKD3 (Homo sapiens) and UniProtKB:O94806-11624291 RGDGO_REF:0000052
Prkd3Ratplasma membrane located_inISOPRKD3 (Homo sapiens) and UniProtKB:O94806-11624291 RGDGO_REF:0000052
Prkd3Ratplasma membrane located_inIEAUniProtKB:O94806 and ensembl:ENSP000002341791600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 13 of 13 rows

Molecular Function
1 to 18 of 18 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Prkd3RatATP binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
Prkd3RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Prkd3RatATP binding enablesIEAInterPro:IPR000719 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Prkd3Ratdiacylglycerol-dependent serine/threonine kinase activity enablesIEAEC:2.7.11.131600115GO_REF:0000003UniProtGO_REF:0000003
Prkd3Ratkinase activity enablesISOPRKD3 (Homo sapiens)1624291 PMID:22228765RGDPMID:22228765
Prkd3Ratkinase activity enablesIEAUniProtKB:O94806 and ensembl:ENSP000002341791600115GO_REF:0000107EnsemblGO_REF:0000107
Prkd3Ratkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
Prkd3Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Prkd3Ratnucleotide binding enablesIEAUniRule:UR0015033411600115GO_REF:0000104UniProtGO_REF:0000104
Prkd3Ratnucleotide binding enablesIEAUniProtKB-KW:KW-05471600115GO_REF:0000043UniProtGO_REF:0000043
Prkd3Ratprotein binding enablesIPIUniProtKB:P630458554790PMID:17196367IntAct 
Prkd3Ratprotein binding enablesISOPRKD3 (Homo sapiens) and UniProtKB:O94806-21624291UniProtKB:Q9UGP5-2 and PMID:32296183RGDPMID:32296183
Prkd3Ratprotein binding enablesISOPRKD3 (Homo sapiens)1624291UniProtKB:P63027 and PMID:17196367RGDPMID:17196367
Prkd3Ratprotein kinase activity enablesIEAInterPro:IPR000719 and InterPro:IPR0082711600115GO_REF:0000002InterProGO_REF:0000002
Prkd3Ratprotein serine/threonine kinase activity enablesIEAInterPro:IPR0157271600115GO_REF:0000002InterProGO_REF:0000002
Prkd3Ratprotein serine/threonine kinase activity enablesIBAMGI:99879 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Prkd3Ratprotein serine/threonine kinase activity enablesIEAUniProtKB-KW:KW-07231600115GO_REF:0000043UniProtGO_REF:0000043
Prkd3Rattransferase activity enablesIEAUniProtKB-KW:KW-08081600115GO_REF:0000043UniProtGO_REF:0000043
1 to 18 of 18 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Protein kinase D 3 is localized in vesicular structures and interacts with vesicle-associated membrane protein 2. Lu G, etal., Cell Signal. 2007 Apr;19(4):867-79. Epub 2006 Nov 16.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:21971046   PMID:22228765   PMID:27369082  



Prkd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8621,784,665 - 21,860,600 (+)NCBIGRCr8
mRatBN7.2616,032,507 - 16,108,444 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,032,585 - 16,108,443 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx616,355,379 - 16,423,921 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0616,677,588 - 16,746,130 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,157,980 - 16,226,554 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.061,546,018 - 1,622,232 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl61,548,415 - 1,622,196 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.061,536,128 - 1,611,876 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.461,727,315 - 1,796,290 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.161,751,738 - 1,764,473 (-)NCBI
Celera615,704,621 - 15,773,170 (+)NCBICelera
Cytogenetic Map6q12NCBI
PRKD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38237,250,502 - 37,324,833 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl237,250,502 - 37,324,833 (-)EnsemblGRCh38hg38GRCh38
GRCh37237,477,645 - 37,551,976 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36237,331,149 - 37,397,726 (-)NCBINCBI36Build 36hg18NCBI36
Build 34237,389,298 - 37,455,873NCBI
Celera237,318,598 - 37,385,166 (-)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef237,217,514 - 37,283,993 (-)NCBIHuRef
CHM1_1237,407,074 - 37,473,671 (-)NCBICHM1_1
T2T-CHM13v2.0237,257,518 - 37,331,821 (-)NCBIT2T-CHM13v2.0
Prkd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391779,256,834 - 79,328,245 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1779,256,834 - 79,328,245 (-)EnsemblGRCm39 Ensembl
GRCm381778,949,405 - 79,020,816 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,949,405 - 79,020,816 (-)EnsemblGRCm38mm10GRCm38
MGSCv371779,348,745 - 79,420,156 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361778,855,607 - 78,918,364 (-)NCBIMGSCv36mm8
Celera1783,270,085 - 83,333,948 (-)NCBICelera
Cytogenetic Map17E3NCBI
cM Map1749.69NCBI
Prkd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554415,051,079 - 5,112,799 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554415,051,079 - 5,112,791 (-)NCBIChiLan1.0ChiLan1.0
PRKD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21289,154,788 - 89,229,111 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A89,158,772 - 89,233,086 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A37,278,043 - 37,352,364 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A38,042,771 - 38,116,394 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A38,042,771 - 38,116,394 (-)Ensemblpanpan1.1panPan2
PRKD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11729,607,484 - 29,696,304 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1729,610,159 - 29,687,550 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1729,421,475 - 29,510,291 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01730,257,459 - 30,346,099 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1730,258,830 - 30,346,080 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11729,484,730 - 29,573,085 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01729,548,330 - 29,639,287 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01729,766,130 - 29,854,593 (-)NCBIUU_Cfam_GSD_1.0
Prkd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629242,313,646 - 42,382,136 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936663979,130 - 1,049,427 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936663979,136 - 1,047,633 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3102,842,229 - 102,941,329 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13102,840,666 - 102,949,128 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23109,438,196 - 109,546,779 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRKD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11470,064,678 - 70,142,790 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1470,072,330 - 70,140,176 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604541,805,140 - 41,881,579 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Prkd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473818,853,963 - 18,927,122 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473818,851,165 - 18,927,177 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Prkd3
366 total Variants

Predicted Target Of
Summary Value
Count of predictions:393
Count of miRNA genes:227
Interacting mature miRNAs:271
Transcripts:ENSRNOT00000007492
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 32 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
8693699Alc37Alcohol consumption QTL 372.60.224drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)6796416721301982Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat

1 to 10 of 32 rows
RH129843  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,108,080 - 16,108,260 (-)MAPPERmRatBN7.2
Rnor_6.061,546,202 - 1,546,381NCBIRnor6.0
Rnor_5.061,536,311 - 1,536,490UniSTSRnor5.0
RGSC_v3.461,727,498 - 1,727,677UniSTSRGSC3.4
Celera615,772,808 - 15,772,987UniSTS
Cytogenetic Map6q11UniSTS
RH131273  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,108,645 - 16,108,825 (-)MAPPERmRatBN7.2
Rnor_6.061,545,637 - 1,545,816NCBIRnor6.0
Rnor_5.061,535,746 - 1,535,925UniSTSRnor5.0
RGSC_v3.461,726,933 - 1,727,112UniSTSRGSC3.4
Celera615,773,373 - 15,773,552UniSTS
RH 3.4 Map632.8UniSTS
Cytogenetic Map6q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000007492   ⟹   ENSRNOP00000007491
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,039,896 - 16,108,443 (+)Ensembl
Rnor_6.0 Ensembl61,548,415 - 1,622,196 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000084528   ⟹   ENSRNOP00000069846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,071,139 - 16,083,871 (+)Ensembl
Rnor_6.0 Ensembl61,570,683 - 1,583,417 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095865   ⟹   ENSRNOP00000079860
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,044,022 - 16,108,443 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000101507   ⟹   ENSRNOP00000077406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,032,585 - 16,041,481 (+)Ensembl
RefSeq Acc Id: NM_001024263   ⟹   NP_001019434
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,792,052 - 21,860,600 (+)NCBI
mRatBN7.2616,039,896 - 16,108,443 (+)NCBI
Rnor_6.061,546,019 - 1,614,851 (-)NCBI
Rnor_5.061,536,128 - 1,611,876 (-)NCBI
RGSC_v3.461,727,315 - 1,796,290 (-)RGD
Celera615,704,621 - 15,773,170 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239629   ⟹   XP_006239691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,981 - 21,860,596 (+)NCBI
mRatBN7.2616,032,819 - 16,108,436 (+)NCBI
Rnor_6.061,547,742 - 1,621,961 (-)NCBI
Rnor_5.061,536,128 - 1,611,876 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006239631   ⟹   XP_006239693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,806,802 - 21,860,596 (+)NCBI
mRatBN7.2616,063,839 - 16,108,444 (+)NCBI
Rnor_6.061,547,742 - 1,591,441 (-)NCBI
Rnor_5.061,536,128 - 1,611,876 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112128   ⟹   XP_038968056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,696 - 21,860,596 (+)NCBI
mRatBN7.2616,032,552 - 16,108,444 (+)NCBI
RefSeq Acc Id: XM_039112129   ⟹   XP_038968057
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,665 - 21,860,596 (+)NCBI
mRatBN7.2616,032,507 - 16,108,444 (+)NCBI
RefSeq Acc Id: XM_063261804   ⟹   XP_063117874
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8621,784,988 - 21,860,596 (+)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: NP_001019434   ⟸   NM_001024263
- UniProtKB: D4A229 (UniProtKB/TrEMBL),   A0A8I6G5U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239691   ⟸   XM_006239629
- Peptide Label: isoform X1
- UniProtKB: D4A229 (UniProtKB/TrEMBL),   A0A8I6G5U2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239693   ⟸   XM_006239631
- Peptide Label: isoform X2
- UniProtKB: A0A8I6G5U2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069846   ⟸   ENSRNOT00000084528
Ensembl Acc Id: ENSRNOP00000007491   ⟸   ENSRNOT00000007492
PH   Phorbol-ester/DAG-type   Protein kinase

Name Modeler Protein Id AA Range Protein Structure
AF-D4A229-F1-model_v2 AlphaFold D4A229 1-890 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13694361
Promoter ID:EPDNEW_R4882
Type:initiation region
Name:Prkd3_2
Description:protein kinase D3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4883  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.061,583,411 - 1,583,471EPDNEW
RGD ID:13694358
Promoter ID:EPDNEW_R4883
Type:initiation region
Name:Prkd3_1
Description:protein kinase D3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R4882  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.061,622,252 - 1,622,312EPDNEW


1 to 40 of 49 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-38496 BioCyc
Ensembl Genes ENSRNOG00000005289 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007492 ENTREZGENE
  ENSRNOT00000007492.8 UniProtKB/TrEMBL
  ENSRNOT00000084528.2 UniProtKB/TrEMBL
  ENSRNOT00000095865 ENTREZGENE
  ENSRNOT00000095865.1 UniProtKB/TrEMBL
  ENSRNOT00000101507.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
  3.30.60.20 UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro C1-like_sf UniProtKB/TrEMBL
  DAG/PE_bd UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  PH_like_dom UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Prot_Kinase_C-like_PE/DAG_bd UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Protein_Kinase_C_mu-related UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:313834 UniProtKB/TrEMBL
NCBI Gene 313834 ENTREZGENE
PANTHER PKC_mu_like UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE D3 UniProtKB/TrEMBL
Pfam C1_1 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PhenoGen Prkd3 PhenoGen
PIRSF PKC_mu_nu_D2 UniProtKB/TrEMBL
PRINTS DAGPEDOMAIN UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
  ZF_DAG_PE_1 UniProtKB/TrEMBL
  ZF_DAG_PE_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005289 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
1 to 40 of 49 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-17 Prkd3  protein kinase D3  Prkcn  protein kinase C, nu  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Prkcn  protein kinase C, nu  Prkcn_predicted  protein kinase C, nu (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Prkcn_predicted  protein kinase C, nu (predicted)      Symbol and Name status set to approved 70820 APPROVED