Predicted to enable co-receptor binding activity and transferrin receptor activity. Involved in acute-phase response. Predicted to be located in cytoplasmic vesicle and plasma membrane. Predicted to be part of HFE-transferrin receptor complex. Predicted to be active in external side of plasma membrane and postsynapse. Used to study hemochromatosis type 3. Human ortholog(s) of this gene implicated in hemochromatosis and hemochromatosis type 3. Orthologous to human TFR2 (transferrin receptor 2); INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
[Clofibrate co-treated with Acetaminophen] affects the expression of TFR2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TFR2 mRNA]
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFR2 mRNA
[Clofibrate co-treated with Acetaminophen] affects the expression of TFR2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TFR2 mRNA]
[perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of TFR2 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of TFR2 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFR2 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TFR2 mRNA
Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response.