Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of USP40 mRNA] | CTD | PMID:31150632 | 1,3-dinitrobenzene | increases expression | EXP | | 6480464 | 3-dinitrobenzene results in increased expression of USP40 mRNA | CTD | PMID:24140754 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of USP40 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of USP40 mRNA | CTD | PMID:33387578 | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of USP40 protein | CTD | PMID:34915118 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | USP40 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of USP40 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | increases expression | ISO | Usp40 (Mus musculus) | 6480464 | Fenretinide results in increased expression of USP40 mRNA | CTD | PMID:28973697 | acrolein | multiple interactions | ISO | USP40 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of USP40 mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | aflatoxin B1 | increases expression | ISO | Usp40 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of USP40 mRNA | CTD | PMID:19770486 | alpha-pinene | multiple interactions | ISO | USP40 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of USP40 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of USP40 mRNA | CTD | PMID:32699268 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of USP40 mRNA | CTD | PMID:30779732 | antirheumatic drug | increases expression | ISO | USP40 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of USP40 mRNA | CTD | PMID:24449571 | aristolochic acid A | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of USP40 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | USP40 (Homo sapiens) | 6480464 | Arsenic affects the methylation of USP40 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | USP40 (Homo sapiens) | 6480464 | Arsenic affects the methylation of USP40 gene | CTD | PMID:25304211 | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of USP40 mRNA | CTD | PMID:33854195 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of USP40 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Usp40 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of USP40 mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of USP40 mRNA | CTD | PMID:30816183 more ... | bisphenol A | increases expression | ISO | USP40 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of USP40 mRNA | CTD | PMID:29275510 | bisphenol F | multiple interactions | ISO | USP40 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of USP40 mRNA | CTD | PMID:28628672 | butanal | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of USP40 mRNA | CTD | PMID:26079696 | caffeine | decreases phosphorylation | ISO | USP40 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of USP40 protein | CTD | PMID:35688186 | calcitriol | increases expression | ISO | USP40 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of USP40 mRNA | CTD | PMID:16002434 | carbamazepine | affects expression | ISO | USP40 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of USP40 mRNA | CTD | PMID:25979313 | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of USP40 mRNA | CTD | PMID:33854195 | chromium(6+) | affects expression | ISO | Usp40 (Mus musculus) | 6480464 | chromium hexavalent ion affects the expression of USP40 mRNA | CTD | PMID:28472532 | coumestrol | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of USP40 mRNA | CTD | PMID:19167446 | cyclosporin A | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of USP40 mRNA | CTD | PMID:25562108 | dexamethasone | multiple interactions | ISO | USP40 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of USP40 mRNA | CTD | PMID:28628672 | dibutyl phthalate | decreases expression | ISO | Usp40 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of USP40 mRNA | CTD | PMID:21266533 | dioxygen | multiple interactions | ISO | Usp40 (Mus musculus) | 6480464 | Oxygen inhibits the reaction [Oxygen deficiency results in increased expression of USP40 mRNA] | CTD | PMID:22629407 | dioxygen | increases expression | ISO | Usp40 (Mus musculus) | 6480464 | Oxygen deficiency results in increased expression of USP40 mRNA | CTD | PMID:22629407 | ethanol | affects expression | ISO | Usp40 (Mus musculus) | 6480464 | Ethanol affects the expression of USP40 mRNA | CTD | PMID:30319688 | FR900359 | decreases phosphorylation | ISO | USP40 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of USP40 protein | CTD | PMID:37730182 | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of USP40 mRNA | CTD | PMID:33854195 | hydralazine | multiple interactions | ISO | USP40 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of USP40 mRNA | CTD | PMID:17183730 | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of USP40 mRNA | CTD | PMID:33854195 | indometacin | multiple interactions | ISO | USP40 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of USP40 mRNA | CTD | PMID:28628672 | iron dichloride | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of USP40 mRNA | CTD | PMID:35984750 | ketoconazole | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | Ketoconazole results in decreased expression of USP40 mRNA | CTD | PMID:36621641 | lead diacetate | increases expression | ISO | Usp40 (Mus musculus) | 6480464 | lead acetate results in increased expression of USP40 mRNA | CTD | PMID:20542052 | lead(0) | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | Lead results in decreased expression of USP40 mRNA | CTD | PMID:19921347 | leflunomide | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of USP40 mRNA | CTD | PMID:28988120 | ozone | multiple interactions | ISO | USP40 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of USP40 mRNA more ... | CTD | PMID:32699268 and PMID:32845096 | paracetamol | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of USP40 mRNA | CTD | PMID:21420995 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of USP40 mRNA | CTD | PMID:33387578 | pirinixic acid | increases expression | ISO | Usp40 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of USP40 mRNA | CTD | PMID:18301758 and PMID:21318169 | pirinixic acid | multiple interactions | ISO | Usp40 (Mus musculus) | 6480464 | PPARA protein affects the reaction [pirinixic acid results in increased expression of USP40 mRNA] | CTD | PMID:21318169 | sunitinib | increases expression | ISO | USP40 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of USP40 mRNA | CTD | PMID:31533062 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of USP40 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of USP40 mRNA | CTD | PMID:31150632 | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of USP40 mRNA | CTD | PMID:33854195 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of USP40 mRNA | CTD | PMID:34492290 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of USP40 mRNA | CTD | PMID:33387578 | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of USP40 protein | CTD | PMID:32519852 | urethane | decreases expression | ISO | USP40 (Homo sapiens) | 6480464 | Urethane results in decreased expression of USP40 mRNA | CTD | PMID:28818685 | valproic acid | multiple interactions | ISO | USP40 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of USP40 mRNA | CTD | PMID:17183730 | valproic acid | affects expression | ISO | USP40 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of USP40 mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of USP40 mRNA | CTD | PMID:23034163 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
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