Usp5 (ubiquitin specific peptidase 5) - Rat Genome Database

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Gene: Usp5 (ubiquitin specific peptidase 5) Rattus norvegicus
Analyze
Symbol: Usp5
Name: ubiquitin specific peptidase 5
RGD ID: 1308438
Description: Predicted to enable cysteine-type deubiquitinase activity and ubiquitin binding activity. Predicted to be involved in several processes, including protein K48-linked deubiquitination; regulation of ubiquitin-dependent protein catabolic process; and regulation protein catabolic process at presynapse. Predicted to be located in presynapse. Predicted to be active in cytosol and nucleus. Orthologous to human USP5 (ubiquitin specific peptidase 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100911959; LOC297593; ubiquitin carboxyl-terminal hydrolase 5; ubiquitin carboxyl-terminal hydrolase 5-like; ubiquitin specific peptidase 5 (isopeptidase T); ubiquitin specific protease 5 (isopeptidase T)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,305,927 - 159,321,345 (-)NCBIGRCr8
mRatBN7.24157,619,663 - 157,634,681 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,847,808 - 163,862,942 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,630,718 - 159,645,852 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,266,340 - 158,281,358 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,332,735 - 157,347,803 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,350,331 - 224,365,479 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,937,706 - 160,952,769 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4146,357,626 - 146,372,628 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp5Ratdevelopmental and epileptic encephalopathy 21  ISOUSP5 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 21ClinVarPMID:28492532
Usp5RatHyperphosphatemic Familial Tumoral Calcinosis 1  ISOUSP5 (Homo sapiens)8554872ClinVar Annotator: match by term: Tumoral calcinosis more ...ClinVarPMID:25378588 and PMID:29389098
Usp5RatKlippel-Feil syndrome 3  ISOUSP5 (Homo sapiens)8554872ClinVar Annotator: match by term: Klippel-Feil syndrome 3 and autosomal dominantClinVarPMID:28492532
Usp5Ratlymphoproliferative syndrome 2  ISOUSP5 (Homo sapiens)8554872ClinVar Annotator: match by term: Lymphoproliferative syndrome 2ClinVarPMID:28492532
Usp5Ratperoxisome biogenesis disorder 2B  ISOUSP5 (Homo sapiens)8554872ClinVar Annotator: match by term: Peroxisome biogenesis disorder 2BClinVarPMID:28492532
Usp5RatTemtamy syndrome  ISOUSP5 (Homo sapiens)8554872ClinVar Annotator: match by term: Temtamy syndromeClinVarPMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp5RatChemical and Drug Induced Liver Injury  ISOUSP5 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25231249

1 to 20 of 102 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp5Rat(-)-epigallocatechin 3-gallate decreases expressionISOUSP5 (Homo sapiens)6480464epigallocatechin gallate results in decreased expression of USP5 mRNACTDPMID:18851785
Usp5Rat1,2-dimethylhydrazine multiple interactionsISOUsp5 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of USP5 mRNACTDPMID:22206623
Usp5Rat1,2-dimethylhydrazine increases expressionISOUsp5 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of USP5 mRNACTDPMID:22206623
Usp5Rat17beta-estradiol increases expressionISOUsp5 (Mus musculus)6480464Estradiol results in increased expression of USP5 mRNACTDPMID:39298647
Usp5Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one affects localizationISOUSP5 (Homo sapiens)6480464Metribolone affects the localization of USP5 proteinCTDPMID:17440980
Usp5Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOUSP5 (Homo sapiens)64804642 more ...CTDPMID:31675489
Usp5Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of USP5 mRNACTDPMID:33387578
Usp5Rat2,3,7,8-Tetrachlorodibenzofuran decreases expressionEXP 64804642 more ...CTDPMID:32109520
Usp5Rat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of USP5 mRNACTDPMID:21346803
Usp5Rat2,6-dimethoxyphenol multiple interactionsISOUSP5 (Homo sapiens)6480464[pyrogallol 1 more ...CTDPMID:38598786
Usp5Rat2-bromohexadecanoic acid multiple interactionsISOUSP5 (Homo sapiens)64804642-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of USP5 protein]CTDPMID:38195004
Usp5Rat2-hydroxypropanoic acid decreases expressionISOUSP5 (Homo sapiens)6480464Lactic Acid results in decreased expression of USP5 mRNACTDPMID:30851411
Usp5Rat3,4-methylenedioxymethamphetamine increases expressionISOUsp5 (Mus musculus)6480464N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of USP5 mRNACTDPMID:20188158
Usp5Rat3-cyanoalanine multiple interactionsISOUsp5 (Mus musculus)64804643-cyanoalanine inhibits the reaction [[N more ...CTDPMID:29129814
Usp5Rat4,4'-sulfonyldiphenol increases expressionISOUsp5 (Mus musculus)6480464bisphenol S results in increased expression of USP5 mRNACTDPMID:39298647
Usp5Rat4,4'-sulfonyldiphenol multiple interactionsEXP 6480464[bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of USP5 mRNACTDPMID:36041667
Usp5Rat4,4'-sulfonyldiphenol decreases methylationISOUsp5 (Mus musculus)6480464bisphenol S results in decreased methylation of USP5 promoterCTDPMID:33297965
Usp5Ratacetamide decreases expressionEXP 6480464acetamide results in decreased expression of USP5 mRNACTDPMID:31881176
Usp5Ratacrylamide increases expressionEXP 6480464Acrylamide results in increased expression of USP5 mRNACTDPMID:28959563
Usp5Ratactinomycin D multiple interactionsISOUSP5 (Homo sapiens)6480464[Dactinomycin co-treated with nutlin 3] results in increased secretion of USP5 proteinCTDPMID:38460933

1 to 20 of 102 rows

Biological Process
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp5Ratnegative regulation of proteasomal ubiquitin-dependent protein catabolic process involved_inISOUSP5 (Homo sapiens)1624291 PMID:37534934RGDPMID:37534934
Usp5Ratnegative regulation of T cell mediated immune response to tumor cell involved_inISOUSP5 (Homo sapiens)1624291 PMID:37208329RGDPMID:37208329
Usp5Ratnegative regulation of ubiquitin-dependent protein catabolic process involved_inISOUSP5 (Homo sapiens)1624291 PMID:24424410RGDPMID:24424410
Usp5Ratnegative regulation of ubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:P45974 and ensembl:ENSP000002292681600115GO_REF:0000107EnsemblGO_REF:0000107
Usp5Ratpositive regulation of proteasomal ubiquitin-dependent protein catabolic process involved_inISOUSP5 (Homo sapiens)1624291 PMID:19098288RGDPMID:19098288
Usp5Ratpositive regulation of proteasomal ubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:P45974 and ensembl:ENSP000002292681600115GO_REF:0000107EnsemblGO_REF:0000107
Usp5Ratprotein deubiquitination involved_inIEAInterPro:IPR001394 and InterPro:IPR0166521600115GO_REF:0000002InterProGO_REF:0000002
Usp5Ratprotein K48-linked deubiquitination involved_inISOUSP5 (Homo sapiens)1624291 PMID:19098288RGDPMID:19098288
Usp5Ratprotein K48-linked deubiquitination involved_inIEAUniProtKB:P45974 and ensembl:ENSP000002292681600115GO_REF:0000107EnsemblGO_REF:0000107
Usp5Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Usp5Ratregulation of protein stability involved_inIBAFB:FBgn0016756 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp5Ratregulation protein catabolic process at presynapse involved_inIEAUniProtKB:P56399 and ensembl:ENSMUSP000000412991600115GO_REF:0000107EnsemblGO_REF:0000107
Usp5Ratregulation protein catabolic process at presynapse involved_inISOUsp5 (Mus musculus)1624291 PMID:25189210RGDPMID:25189210
1 to 13 of 13 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp5Ratcytoplasm is_active_inISOUSP5 (Homo sapiens)1624291 PMID:37208329RGDPMID:37208329
Usp5Ratcytosol is_active_inIBAFB:FBgn0016756 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp5Ratnucleus is_active_inIBAFB:FBgn0016756 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp5Ratpresynapse located_inIEAGO:01402511600115GO_REF:0000108GOCGO_REF:0000108

Molecular Function
1 to 20 of 21 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp5Ratcysteine-type deubiquitinase activity enablesISOUSP5 (Homo sapiens)1624291 PMID:24424410 and PMID:26235645RGDPMID:24424410 and PMID:26235645
Usp5Ratcysteine-type deubiquitinase activity enablesIEAUniRule:UR000859761 and UniRule:UR0008807561600115GO_REF:0000104UniProtGO_REF:0000104
Usp5Ratcysteine-type deubiquitinase activity enablesIEAUniProtKB:P45974 and ensembl:ENSP000002292681600115GO_REF:0000107EnsemblGO_REF:0000107
Usp5Ratcysteine-type deubiquitinase activity enablesIEAInterPro:IPR001394 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Usp5Ratcysteine-type deubiquitinase activity enablesIBAFB:FBgn0005632 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp5Ratcysteine-type deubiquitinase activity enablesIEAEC:3.4.19.121600115GO_REF:0000003UniProtGO_REF:0000003
Usp5Ratcysteine-type deubiquitinase activity enablesIEAUniRule:UR0008597611600115GO_REF:0000104UniProtGO_REF:0000104
Usp5Ratcysteine-type peptidase activity enablesIEAUniProtKB-KW:KW-07881600115GO_REF:0000043UniProtGO_REF:0000043
Usp5Ratdeubiquitinase activity enablesIEAUniProtKB:P45974 and ensembl:ENSP000002292681600115GO_REF:0000107EnsemblGO_REF:0000107
Usp5Ratdeubiquitinase activity enablesISOUSP5 (Homo sapiens)1624291 PMID:26917723 and PMID:37534934RGDPMID:26917723 and PMID:37534934
Usp5Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Usp5Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Usp5Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Usp5Ratprotein binding enablesISOUsp5 (Mus musculus)1624291PR:E9Q9D5 more ...RGDPMID:19156909 and PMID:23055941
Usp5Ratprotein binding enablesISOUSP5 (Homo sapiens) and UniProtKB:P45974-21624291UniProtKB:O14773 more ...RGDPMID:32296183 and PMID:32814053
Usp5Ratprotein binding enablesISOUSP5 (Homo sapiens)1624291UniProtKB:O75528 more ...RGDPMID:16189514 more ...
Usp5Ratubiquitin binding enablesISOUSP5 (Homo sapiens)1624291 PMID:24424410RGDPMID:24424410
Usp5Ratubiquitin binding enablesIEAUniProtKB:P45974 and ensembl:ENSP000002292681600115GO_REF:0000107EnsemblGO_REF:0000107
Usp5Ratzinc ion binding enablesIEAUniRule:UR0008597611600115GO_REF:0000104UniProtGO_REF:0000104
Usp5Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:19098288   PMID:19182904   PMID:22871113   PMID:23375434   PMID:24424410  



Usp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84159,305,927 - 159,321,345 (-)NCBIGRCr8
mRatBN7.24157,619,663 - 157,634,681 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,847,808 - 163,862,942 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04159,630,718 - 159,645,852 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04158,266,340 - 158,281,358 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04157,332,735 - 157,347,803 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,350,331 - 224,365,479 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,937,706 - 160,952,769 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4146,357,626 - 146,372,628 (-)NCBICelera
Cytogenetic Map4q42NCBI
USP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,852,150 - 6,866,632 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,852,148 - 6,866,632 (+)EnsemblGRCh38hg38GRCh38
GRCh37126,961,314 - 6,975,796 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,831,546 - 6,846,057 (+)NCBINCBI36Build 36hg18NCBI36
Build 34126,831,583 - 6,846,054NCBI
Celera128,578,571 - 8,593,082 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,815,013 - 6,829,524 (+)NCBIHuRef
CHM1_1126,960,283 - 6,974,794 (+)NCBICHM1_1
T2T-CHM13v2.0126,861,449 - 6,875,929 (+)NCBIT2T-CHM13v2.0
Usp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,791,982 - 124,806,404 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,791,982 - 124,806,447 (-)EnsemblGRCm39 Ensembl
GRCm386124,815,019 - 124,829,484 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,815,019 - 124,829,484 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,765,037 - 124,779,465 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,780,638 - 124,795,066 (-)NCBIMGSCv36mm8
Celera6126,491,148 - 126,505,576 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
Usp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,451,622 - 4,466,832 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,451,530 - 4,466,832 (+)NCBIChiLan1.0ChiLan1.0
USP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21012,414,488 - 12,429,794 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11212,411,246 - 12,426,552 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0126,983,941 - 6,998,469 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,895,416 - 6,909,936 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,895,416 - 6,909,936 (+)Ensemblpanpan1.1panPan2
USP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,158,850 - 38,172,689 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,158,834 - 38,172,071 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,444,116 - 8,457,897 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,511,741 - 38,525,542 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,511,746 - 38,524,959 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,385,805 - 38,399,013 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,426,829 - 38,440,619 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,922,848 - 7,936,630 (+)NCBIUU_Cfam_GSD_1.0
Usp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,284,676 - 102,298,641 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709952,182 - 966,498 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936709952,225 - 966,429 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,843,745 - 63,858,716 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,843,742 - 63,858,835 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,279,250 - 66,294,259 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,885,401 - 6,899,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,885,311 - 6,898,442 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,323,576 - 1,338,147 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,519,113 - 3,532,687 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,519,106 - 3,532,690 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Usp5
50 total Variants

Predicted Target Of
Summary Value
Count of predictions:272
Count of miRNA genes:167
Interacting mature miRNAs:186
Transcripts:ENSRNOT00000020785
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 36 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat

1 to 10 of 36 rows
AI411387  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,619,843 - 157,620,056 (-)MAPPERmRatBN7.2
mRatBN7.24157,619,843 - 157,620,056 (+)MAPPERmRatBN7.2
Rnor_6.04157,332,936 - 157,333,148NCBIRnor6.0
Rnor_6.0920,212,509 - 20,212,721NCBIRnor6.0
Rnor_5.04224,350,532 - 224,350,744UniSTSRnor5.0
Rnor_5.0919,088,485 - 19,088,697UniSTSRnor5.0
RGSC_v3.44160,937,902 - 160,938,114UniSTSRGSC3.4
Celera4146,357,822 - 146,358,034UniSTS
RH 3.4 Map41005.8UniSTS
Cytogenetic Map4q42UniSTS
MARC_7181-7182:996687603:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,622,121 - 157,622,508 (-)MAPPERmRatBN7.2
mRatBN7.24157,622,121 - 157,622,508 (+)MAPPERmRatBN7.2
Rnor_6.0920,210,057 - 20,210,443NCBIRnor6.0
Rnor_6.04157,335,214 - 157,335,600NCBIRnor6.0
Rnor_5.0919,086,033 - 19,086,419UniSTSRnor5.0
Rnor_5.04224,352,810 - 224,353,196UniSTSRnor5.0
RGSC_v3.44160,940,180 - 160,940,566UniSTSRGSC3.4
Celera4146,360,100 - 146,360,486UniSTS
Cytogenetic Map4q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000020785   ⟹   ENSRNOP00000020785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,619,648 - 157,634,711 (-)Ensembl
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109840   ⟹   ENSRNOP00000078694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)Ensembl
RefSeq Acc Id: NM_001106619   ⟹   NP_001100089
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,305,938 - 159,320,956 (-)NCBI
mRatBN7.24157,619,663 - 157,634,681 (-)NCBI
Rnor_6.04157,332,740 - 157,347,803 (-)NCBI
Rnor_5.04224,350,331 - 224,365,479 (-)NCBI
RGSC_v3.44160,937,706 - 160,952,769 (-)RGD
Celera4146,357,626 - 146,372,628 (-)RGD
Sequence:
RefSeq Acc Id: NM_001394369   ⟹   NP_001381298
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,305,938 - 159,320,956 (-)NCBI
mRatBN7.24157,619,663 - 157,634,681 (-)NCBI
RefSeq Acc Id: XM_063285907   ⟹   XP_063141977
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84159,305,927 - 159,321,345 (-)NCBI
Protein RefSeqs NP_001100089 (Get FASTA)   NCBI Sequence Viewer  
  NP_001381298 (Get FASTA)   NCBI Sequence Viewer  
  XP_063141977 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM01922 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020785
  ENSRNOP00000020785.4
  ENSRNOP00000078694.1
RefSeq Acc Id: NP_001100089   ⟸   NM_001106619
- Peptide Label: isoform 1
- UniProtKB: D3ZVQ0 (UniProtKB/TrEMBL),   A6ILL7 (UniProtKB/TrEMBL),   A0A8I5ZLA4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020785   ⟸   ENSRNOT00000020785
Ensembl Acc Id: ENSRNOP00000078694   ⟸   ENSRNOT00000109840
RefSeq Acc Id: NP_001381298   ⟸   NM_001394369
- Peptide Label: isoform 2
- UniProtKB: A0A8I5ZLA4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063141977   ⟸   XM_063285907
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZLA4 (UniProtKB/TrEMBL)
UBA   UBP-type   USP

Name Modeler Protein Id AA Range Protein Structure
AF-D3ZVQ0-F1-model_v2 AlphaFold D3ZVQ0 1-858 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13693391
Promoter ID:EPDNEW_R3916
Type:initiation region
Name:Usp5_1
Description:ubiquitin specific peptidase 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04157,347,773 - 157,347,833EPDNEW


1 to 40 of 44 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-43065 BioCyc
Ensembl Genes ENSRNOG00000015409 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020785 ENTREZGENE
  ENSRNOT00000020785.6 UniProtKB/TrEMBL
  ENSRNOT00000109840.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
InterPro Papain_like_cys_pep_sf UniProtKB/TrEMBL
  Pept_C19ubi-hydrolase_C_CS UniProtKB/TrEMBL
  Peptidase_C19 UniProtKB/TrEMBL
  Ub_carboxyl-term_hydrolase UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
  UBA/transl_elong_EF1B_N_euk UniProtKB/TrEMBL
  Ubiquitinyl_hydrolase UniProtKB/TrEMBL
  UBP13_Znf-UBP_var UniProtKB/TrEMBL
  UBP5_UBA1 UniProtKB/TrEMBL
  UCH/PAN2 UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
KEGG Report rno:297593 UniProtKB/TrEMBL
NCBI Gene 297593 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
Pfam UBA_7 UniProtKB/TrEMBL
  UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
  zf-UBP_var UniProtKB/TrEMBL
PhenoGen Usp5 PhenoGen
PIRSF UBP UniProtKB/TrEMBL
PROSITE UBA UniProtKB/TrEMBL
  UCH_2_1 UniProtKB/TrEMBL
  UCH_2_2 UniProtKB/TrEMBL
  UCH_2_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015409 RatGTEx
SMART UBA UniProtKB/TrEMBL
  ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
1 to 40 of 44 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Usp5  ubiquitin specific peptidase 5  LOC100911959  ubiquitin carboxyl-terminal hydrolase 5-like  Data merged from RGD:6489834 737654 PROVISIONAL
2016-04-13 Usp5  ubiquitin specific peptidase 5  Usp5  ubiquitin specific peptidase 5 (isopeptidase T)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911959  ubiquitin carboxyl-terminal hydrolase 5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-04 Usp5  ubiquitin specific peptidase 5 (isopeptidase T)  Usp5_predicted  ubiquitin specific protease 5 (isopeptidase T) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Usp5_predicted  ubiquitin specific protease 5 (isopeptidase T) (predicted)      Symbol and Name status set to approved 70820 APPROVED