Akr1b10 (aldo-keto reductase family 1 member B10) - Rat Genome Database

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Gene: Akr1b10 (aldo-keto reductase family 1 member B10) Rattus norvegicus
Analyze
Symbol: Akr1b10 (Ensembl: Akr1b8)
Name: aldo-keto reductase family 1 member B10 (Ensembl:aldo-keto reductase family 1, member B8)
RGD ID: 1308277
Description: Enables NADP binding activity; alcohol dehydrogenase (NADP+) activity; and retinal binding activity. Involved in polyol metabolic process; retinal metabolic process; and retinol metabolic process. Predicted to be located in extracellular region and lysosome. Predicted to be active in cytosol and mitochondrion. Orthologous to several human genes including AKR1B10 (aldo-keto reductase family 1 member B10); PARTICIPATES IN retinol metabolic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: aldo-keto reductase family 1, member B10 (aldose reductase); aldose reductase-related protein 1-like; LOC100910708; LOC296972
RGD Orthologs
Human
Mouse
Bonobo
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8464,005,632 - 64,027,860 (+)NCBIGRCr8
mRatBN7.2463,038,459 - 63,060,336 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl463,040,169 - 63,053,852 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx467,989,273 - 68,004,664 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0463,904,967 - 63,920,356 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0462,307,393 - 62,322,778 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0461,813,265 - 61,830,371 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl461,771,970 - 61,828,657 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0461,550,785 - 61,568,072 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4461,755,871 - 61,771,264 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1462,032,000 - 62,047,393 (+)NCBI
Celera458,091,866 - 58,107,253 (+)NCBICelera
Cytogenetic Map4q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Akr1b10Ratpleomorphic xanthoastrocytoma  ISOAKR1B10 (Homo sapiens)8554872ClinVar Annotator: match by term: Pleomorphic xanthoastrocytomaClinVarPMID:28299358
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Akr1b10Ratautism spectrum disorder  ISOAKR1B10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:35663546
Akr1b10RatColorectal Neoplasms  ISOAKR1B10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:17597105
Akr1b10Ratcontact dermatitis  ISOAKR1B10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25724174
Akr1b10Ratdisease of cellular proliferation  ISOAKR1B10 (Homo sapiens)11554173CTD Direct Evidence: therapeuticCTDPMID:17329238
Akr1b10RatEndometrial Neoplasms  ISOAKR1B10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:23146748
Akr1b10Rathepatocellular carcinoma  ISOAKR1B10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21472284
Akr1b10Ratmelanoma  ISOAKR1B10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21499247
Akr1b10RatNeoplasm Invasiveness  ISOAKR1B10 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25686905

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Akr1b10Rat(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid multiple interactionsISOAKR1B10 (Homo sapiens)6480464zopolrestat inhibits the reaction [AKR1B10 protein results in increased reduction of Daunorubicin] and zopolrestat inhibits the reaction [AKR1B10 protein results in increased reduction of Glyceraldehyde]CTDPMID:19028477
Akr1b10Rat(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid decreases activityISOAKR1B10 (Homo sapiens)6480464zopolrestat results in decreased activity of AKR1B10 protein and zopolrestat results in decreased activity of AKR1B10 protein mutant formCTDPMID:18325492
Akr1b10Rat(E)-cinnamyl alcohol increases expressionISOAKR1B10 (Homo sapiens)6480464cinnamyl alcohol results in increased expression of AKR1B10 mRNACTDPMID:20566472
Akr1b10Rat(E,E)-2,4-hexadienal increases reductionISOAKR1B10 (Homo sapiens)6480464AKR1B10 protein results in increased reduction of 2 more ...CTDPMID:21329684
Akr1b10Rat(R)-acetoin increases reductionISOAKR1B10 (Homo sapiens)6480464AKR1B10 protein results in increased reduction of AcetoinCTDPMID:23295224
Akr1b10Rat(R)-acetoin multiple interactionsISOAKR1B10 (Homo sapiens)6480464[AKR1B10 protein results in increased reduction of Acetoin] which results in increased chemical synthesis of 2 more ...CTDPMID:23295224
Akr1b10Rat1,2-dimethylhydrazine increases expressionISOAkr1b10 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of AKR1B10 mRNACTDPMID:22206623
Akr1b10Rat1-chloro-2,4-dinitrobenzene increases expressionISOAKR1B10 (Homo sapiens)6480464Dinitrochlorobenzene results in increased expression of AKR1B10 mRNACTDPMID:20566472
Akr1b10Rat13-dihydrodaunorubicin multiple interactionsISOAKR1B10 (Homo sapiens)6480464[AKR1B10 protein results in increased reduction of Daunorubicin] which results in increased chemical synthesis of daunorubicinolCTDPMID:19028477
Akr1b10Rat17beta-estradiol decreases expressionISOAKR1B10 (Homo sapiens)6480464Estradiol results in decreased expression of AKR1B10 mRNACTDPMID:25321415
Akr1b10Rat17beta-estradiol multiple interactionsEXP 6480464[bisphenol A co-treated with Estradiol] results in increased expression of AKR1B10 mRNACTDPMID:26496021
Akr1b10Rat17beta-estradiol multiple interactionsISOAKR1B10 (Homo sapiens)6480464[Estradiol co-treated with TGFB1 protein] results in decreased expression of AKR1B10 mRNA and [Progesterone co-treated with Estradiol] results in decreased expression of AKR1B10 mRNACTDPMID:17404688 and PMID:30165855
Akr1b10Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOAKR1B10 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of AKR1B10 mRNACTDPMID:20106945 more ...
Akr1b10Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of AKR1B10 mRNACTDPMID:33387578
Akr1b10Rat2-(chloromethyl)pyridine increases expressionISOAKR1B10 (Homo sapiens)64804642-chloromethylpyridine results in increased expression of AKR1B10 mRNACTDPMID:26198647
Akr1b10Rat2-acetamidofluorene multiple interactionsEXP 6480464[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased expression of AKR1B10 mRNACTDPMID:14656948
Akr1b10Rat2-acetamidofluorene increases expressionISOAKR1B10 (Homo sapiens)64804642-Acetylaminofluorene results in increased expression of AKR1B10 mRNACTDPMID:26198647
Akr1b10Rat2-hexenal increases reductionISOAKR1B10 (Homo sapiens)6480464AKR1B10 protein results in increased reduction of 2-hexenal and AKR1B10 protein results in increased reduction of 2-hexenal metaboliteCTDPMID:21329684
Akr1b10Rat2-hydroxypropanoic acid increases expressionISOAKR1B10 (Homo sapiens)6480464Lactic Acid results in increased expression of AKR1B10 mRNACTDPMID:20566472
Akr1b10Rat2-hydroxypropanoic acid decreases expressionISOAKR1B10 (Homo sapiens)6480464Lactic Acid results in decreased expression of AKR1B10 mRNACTDPMID:30851411

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Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Akr1b10Ratcytosol is_active_inIBAMGI:1353494 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Akr1b10Ratextracellular region located_inISOAKR1B10 (Homo sapiens)1624291 PMID:21585341RGDPMID:21585341
Akr1b10Ratlysosome located_inISOAKR1B10 (Homo sapiens)1624291 PMID:21585341RGDPMID:21585341
Akr1b10Ratmitochondrion is_active_inIBAPANTHER:PTN000199166 and UniProtKB:C9JRZ81600115GO_REF:0000033GO_CentralGO_REF:0000033

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Akr1b10Ratretinol metabolic pathway   ISOAKR1B10 (Homo sapiens)6903957 RGD 
Akr1b10Ratretinol metabolic pathway   IDA 6903952 RGD 

1 to 11 of 11 rows
#
Reference Title
Reference Citation
1. Properties and tissue distribution of a novel aldo-keto reductase encoding in a rat gene (Akr1b10). Endo S, etal., Arch Biochem Biophys. 2010 Nov 15;503(2):230-7. Epub 2010 Aug 13.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Aldo-keto reductases and bioactivation/detoxication. Jin Y and Penning TM, Annu Rev Pharmacol Toxicol. 2007;47:263-92.
5. Meta-analysis of three diabetes population studies: association of inactive ALDH2 genotype with maternal inheritance of diabetes. Murata C, etal., Diabetes Res Clin Pract. 2004 Dec;66 Suppl 1:S145-7.
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. ALDH2/ADH2 polymorphism associated with vasculopathy and neuropathy in type 2 diabetes. Suzuki Y, etal., Alcohol Clin Exp Res. 2004 Aug;28(8 Suppl Proceedings):111S-116S.
11. Aldehyde dehydrogenase 2 genotype in type 1 diabetes mellitus. Suzuki Y, etal., Diabetes Res Clin Pract. 2003 May;60(2):139-41.
1 to 11 of 11 rows
PMID:12732097   PMID:18614015   PMID:19013440   PMID:19563777   PMID:20837989   PMID:21187079   PMID:21851338   PMID:23376485   PMID:29383608  



Akr1b10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8464,005,632 - 64,027,860 (+)NCBIGRCr8
mRatBN7.2463,038,459 - 63,060,336 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl463,040,169 - 63,053,852 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx467,989,273 - 68,004,664 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0463,904,967 - 63,920,356 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0462,307,393 - 62,322,778 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0461,813,265 - 61,830,371 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl461,771,970 - 61,828,657 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0461,550,785 - 61,568,072 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4461,755,871 - 61,771,264 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1462,032,000 - 62,047,393 (+)NCBI
Celera458,091,866 - 58,107,253 (+)NCBICelera
Cytogenetic Map4q22NCBI
AKR1B10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387134,527,567 - 134,541,412 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7134,527,567 - 134,541,412 (+)EnsemblGRCh38hg38GRCh38
GRCh377134,212,319 - 134,226,164 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367133,862,939 - 133,876,700 (+)NCBINCBI36Build 36hg18NCBI36
Build 347133,669,653 - 133,683,413NCBI
Celera7128,949,765 - 128,963,585 (+)NCBICelera
Cytogenetic Map7q33NCBI
HuRef7128,514,188 - 128,528,007 (+)NCBIHuRef
CHM1_17134,146,625 - 134,160,442 (+)NCBICHM1_1
T2T-CHM13v2.07135,835,650 - 135,849,492 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27133,556,663 - 133,570,483 (+)NCBI
Akr1b10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39634,361,182 - 34,373,884 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl634,361,153 - 34,373,885 (+)EnsemblGRCm39 Ensembl
GRCm38634,384,247 - 34,396,949 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl634,384,218 - 34,396,950 (+)EnsemblGRCm38mm10GRCm38
MGSCv37634,334,247 - 34,346,949 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36634,314,405 - 34,327,107 (+)NCBIMGSCv36mm8
Celera634,380,662 - 34,393,359 (+)NCBICelera
Cytogenetic Map6B1NCBI
cM Map614.93NCBI
AKR1B10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26171,343,443 - 171,357,364 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1723,353,774 - 23,367,619 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07126,486,012 - 126,499,852 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17138,992,802 - 139,006,042 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7138,992,835 - 139,006,003 (+)Ensemblpanpan1.1panPan2

.

.
Variants in Akr1b10
178 total Variants

Predicted Target Of
Summary Value
Count of predictions:143
Count of miRNA genes:116
Interacting mature miRNAs:121
Transcripts:ENSRNOT00000013133
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 54 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711470578881294Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
61475Aia2Adjuvant induced arthritis QTL 25.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)43950527573892441Rat

1 to 10 of 54 rows



alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
3 11 43 82 57 60 41 19 41 160 73 74 35 41 19



Ensembl Acc Id: ENSRNOT00000013073   ⟹   ENSRNOP00000013073
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl462,997,161 - 63,008,866 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000013133   ⟹   ENSRNOP00000013133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl462,019,970 - 62,030,874 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000078996   ⟹   ENSRNOP00000068585
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl462,997,161 - 63,010,097 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098758   ⟹   ENSRNOP00000082845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl462,997,249 - 63,010,096 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116609   ⟹   ENSRNOP00000090343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl462,997,245 - 63,010,087 (+)Ensembl
RefSeq Acc Id: NM_001013084   ⟹   NP_001013102
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,005,632 - 64,021,025 (+)NCBI
mRatBN7.2463,038,459 - 63,053,855 (+)NCBI
Rnor_6.0461,813,265 - 61,828,658 (+)NCBI
Rnor_5.0461,550,785 - 61,568,072 (+)NCBI
RGSC_v3.4461,755,871 - 61,771,264 (+)RGD
Celera458,091,866 - 58,107,253 (+)RGD
Sequence:
RefSeq Acc Id: XM_039107291   ⟹   XP_038963219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,007,221 - 64,027,860 (+)NCBI
mRatBN7.2463,040,064 - 63,054,471 (+)NCBI
RefSeq Acc Id: XM_039107292   ⟹   XP_038963220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,011,356 - 64,027,860 (+)NCBI
mRatBN7.2463,044,186 - 63,054,471 (+)NCBI
RefSeq Acc Id: XR_001837481
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8464,007,232 - 64,027,860 (+)NCBI
mRatBN7.2463,040,064 - 63,060,336 (+)NCBI
Rnor_6.0461,814,735 - 61,830,371 (+)NCBI
Sequence:
1 to 12 of 12 rows
Protein RefSeqs NP_001013102 (Get FASTA)   NCBI Sequence Viewer  
  XP_038963219 (Get FASTA)   NCBI Sequence Viewer  
  XP_038963220 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79133 (Get FASTA)   NCBI Sequence Viewer  
  EDM15306 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000013073.3
  ENSRNOP00000065713
  ENSRNOP00000065713.1
  ENSRNOP00000068585.2
  ENSRNOP00000079554.1
  ENSRNOP00000082845.1
  ENSRNOP00000090343.1
1 to 12 of 12 rows
RefSeq Acc Id: NP_001013102   ⟸   NM_001013084
- UniProtKB: Q6AY99 (UniProtKB/TrEMBL),   M0R8B8 (UniProtKB/TrEMBL),   A0A8I5ZN93 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038963219   ⟸   XM_039107291
- Peptide Label: isoform X1
- UniProtKB: Q6AY99 (UniProtKB/TrEMBL),   M0R8B8 (UniProtKB/TrEMBL),   A0A8I5ZN93 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963220   ⟸   XM_039107292
- Peptide Label: isoform X2
- UniProtKB: A6IEM0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000013133   ⟸   ENSRNOT00000013133
Ensembl Acc Id: ENSRNOP00000068585   ⟸   ENSRNOT00000078996
NADP-dependent oxidoreductase

Name Modeler Protein Id AA Range Protein Structure
AF-F7EMK8-F1-model_v2 AlphaFold F7EMK8 1-295 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 38 of 38 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-45277 BioCyc
Ensembl Genes ENSRNOG00000009734 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000027433 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000013073.5 UniProtKB/TrEMBL
  ENSRNOT00000074951 ENTREZGENE
  ENSRNOT00000074951.3 UniProtKB/TrEMBL
  ENSRNOT00000078996.2 UniProtKB/TrEMBL
  ENSRNOT00000098758.1 UniProtKB/TrEMBL
  ENSRNOT00000114062.1 UniProtKB/TrEMBL
  ENSRNOT00000116609.1 UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.100 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7127413 IMAGE-MGC_LOAD
InterPro Aldo/ket_reductase_CS UniProtKB/TrEMBL
  Aldo/keto_reductase_sg UniProtKB/TrEMBL
  NADP_OxRdtase_dom UniProtKB/TrEMBL
  NADP_OxRdtase_dom_sf UniProtKB/TrEMBL
KEGG Report rno:296972 UniProtKB/TrEMBL
MGC_CLONE MGC:94143 IMAGE-MGC_LOAD
NCBI Gene 296972 ENTREZGENE
PANTHER ALDO/KETO REDUCTASE UniProtKB/TrEMBL
Pfam Aldo_ket_red UniProtKB/TrEMBL
PhenoGen Akr1b10 PhenoGen
PIRSF AKR UniProtKB/TrEMBL
PRINTS ALDKETRDTASE UniProtKB/TrEMBL
PROSITE ALDOKETO_REDUCTASE_1 UniProtKB/TrEMBL
  ALDOKETO_REDUCTASE_2 UniProtKB/TrEMBL
  ALDOKETO_REDUCTASE_3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009734 RatGTEx
  ENSRNOG00000027433 RatGTEx
Superfamily-SCOP Aldo/ket_red UniProtKB/TrEMBL
UniProt A0A0G2JT64_RAT UniProtKB/TrEMBL
  A0A8I5ZN93 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZY17_RAT UniProtKB/TrEMBL
  A0A8I6ADG6_RAT UniProtKB/TrEMBL
  A6IEM0 ENTREZGENE, UniProtKB/TrEMBL
  G3V786_RAT UniProtKB/TrEMBL
  M0R8B8 ENTREZGENE, UniProtKB/TrEMBL
  Q6AY99 ENTREZGENE, UniProtKB/TrEMBL
1 to 38 of 38 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Akr1b10  aldo-keto reductase family 1 member B10  LOC100910708  aldose reductase-related protein 1-like  Data merged from RGD:6496873 737654 PROVISIONAL
2016-06-08 Akr1b10  aldo-keto reductase family 1 member B10  Akr1b10  aldo-keto reductase family 1, member B10 (aldose reductase)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100910708  aldose reductase-related protein 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Akr1b10  aldo-keto reductase family 1, member B10 (aldose reductase)  Akr1b10_predicted  aldo-keto reductase family 1, member B10 (aldose reductase) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Akr1b10_predicted  aldo-keto reductase family 1, member B10 (aldose reductase) (predicted)      Symbol and Name status set to approved 70820 APPROVED