Usp44 (ubiquitin specific peptidase 44) - Rat Genome Database

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Gene: Usp44 (ubiquitin specific peptidase 44) Rattus norvegicus
Analyze
Symbol: Usp44
Name: ubiquitin specific peptidase 44
RGD ID: 1308216
Description: Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in several processes, including antiviral innate immune response; negative regulation of ubiquitin protein ligase activity; and regulation of mitotic metaphase/anaphase transition. Predicted to be active in cytoplasm and nucleus. Orthologous to human USP44 (ubiquitin specific peptidase 44); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC314746; ubiquitin carboxyl-terminal hydrolase 44; ubiquitin specific protease 44; ubiquitin thiolesterase 44
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8730,251,142 - 30,301,185 (+)NCBIGRCr8
mRatBN7.2728,364,169 - 28,412,039 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl728,364,033 - 28,410,053 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx730,354,579 - 30,400,607 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0732,516,806 - 32,562,843 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0732,294,256 - 32,340,284 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0734,714,293 - 34,759,352 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl734,744,483 - 34,759,206 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0734,773,627 - 34,818,325 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4730,898,472 - 30,971,342 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1730,965,952 - 30,991,469 (+)NCBI
Celera725,461,222 - 25,507,052 (+)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 44 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp44Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISOUsp44 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Usp44Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISOUsp44 (Mus musculus)6480464[2 more ...CTDPMID:25510870
Usp44Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOUSP44 (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of USP44 mRNACTDPMID:21632981
Usp44Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of USP44 mRNACTDPMID:33387578
Usp44Ratall-trans-retinoic acid decreases expressionISOUSP44 (Homo sapiens)6480464Tretinoin results in decreased expression of USP44 mRNACTDPMID:21934132
Usp44Ratalpha-Zearalanol increases expressionEXP 6480464Zeranol results in increased expression of USP44 mRNACTDPMID:35163327
Usp44Ratamphetamine decreases expressionEXP 6480464Amphetamine results in decreased expression of USP44 mRNACTDPMID:30779732
Usp44Ratarsane increases methylationISOUSP44 (Homo sapiens)6480464Arsenic results in increased methylation of USP44 promoterCTDPMID:21291286
Usp44Ratarsenic atom increases methylationISOUSP44 (Homo sapiens)6480464Arsenic results in increased methylation of USP44 promoterCTDPMID:21291286
Usp44Ratbenzo[a]pyrene increases methylationISOUSP44 (Homo sapiens)6480464Benzo(a)pyrene results in increased methylation of USP44 5' UTRCTDPMID:27901495
Usp44Ratbenzo[a]pyrene affects methylationISOUSP44 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of USP44 promoterCTDPMID:27901495
Usp44Ratbenzo[a]pyrene diol epoxide I affects expressionISOUSP44 (Homo sapiens)64804647 more ...CTDPMID:20382639
Usp44Ratbis(2-ethylhexyl) phthalate decreases expressionISOUSP44 (Homo sapiens)6480464Diethylhexyl Phthalate results in decreased expression of USP44 mRNACTDPMID:31163220
Usp44Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of USP44 mRNACTDPMID:25181051
Usp44Ratbisphenol A decreases methylationISOUSP44 (Homo sapiens)6480464bisphenol A results in decreased methylation of USP44 geneCTDPMID:31601247
Usp44Ratbisphenol A increases expressionISOUSP44 (Homo sapiens)6480464bisphenol A results in increased expression of USP44 mRNACTDPMID:29275510
Usp44Ratbisphenol F decreases expressionISOUsp44 (Mus musculus)6480464bisphenol F results in decreased expression of USP44 mRNACTDPMID:38685157
Usp44Ratcarbamazepine affects expressionISOUSP44 (Homo sapiens)6480464Carbamazepine affects the expression of USP44 mRNACTDPMID:25979313
Usp44RatCGP 52608 multiple interactionsISOUSP44 (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to USP44 gene]CTDPMID:28238834
Usp44Ratcisplatin increases expressionISOUSP44 (Homo sapiens)6480464Cisplatin results in increased expression of USP44 mRNACTDPMID:27594783

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Biological Process
1 to 20 of 20 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp44Ratantiviral innate immune response involved_inISOUSP44 (Homo sapiens)1624291 PMID:31968013RGDPMID:31968013
Usp44Ratantiviral innate immune response involved_inIEAUniProtKB:Q9H0E7 and ensembl:ENSP000002584991600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratbiological_process  ND 159840710/2014: no relevant rat dataRGD 
Usp44Ratcell division involved_inIEAUniProtKB-KW:KW-01321600115GO_REF:0000043UniProtGO_REF:0000043
Usp44Ratchromosome segregation involved_inISOUsp44 (Mus musculus)1624291 PMID:23187126RGDPMID:23187126
Usp44Ratchromosome segregation involved_inIEAUniProtKB:Q8C2S0 and ensembl:ENSMUSP000001490201600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratnegative regulation of mitotic metaphase/anaphase transition involved_inISOUSP44 (Homo sapiens)1624291 PMID:17443180RGDPMID:17443180
Usp44Ratnegative regulation of mitotic metaphase/anaphase transition involved_inIEAUniProtKB:Q9H0E7 and ensembl:ENSP000002584991600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratnegative regulation of ubiquitin protein ligase activity involved_inISOUSP44 (Homo sapiens)1624291 PMID:17443180RGDPMID:17443180
Usp44Ratproteasome-mediated ubiquitin-dependent protein catabolic process involved_inISOUsp44 (Mus musculus)1624291 PMID:21853124RGDPMID:21853124
Usp44Ratproteasome-mediated ubiquitin-dependent protein catabolic process involved_inIEAUniProtKB:Q8C2S0 and ensembl:ENSMUSP000001490201600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratprotein deubiquitination involved_inISOUSP44 (Homo sapiens)1624291 PMID:17443180 and PMID:20402667RGDPMID:17443180 and PMID:20402667
Usp44Ratprotein deubiquitination involved_inIEAInterPro:IPR0013941600115GO_REF:0000002InterProGO_REF:0000002
Usp44Ratprotein deubiquitination involved_inIEAUniProtKB:Q9H0E7 and ensembl:ENSP000002584991600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratproteolysis involved_inIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Usp44Ratregulation of cell cycle process involved_inIBAMGI:3045318 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp44Ratregulation of mitotic cell cycle spindle assembly checkpoint involved_inISOUsp44 (Mus musculus)1624291 PMID:21853124RGDPMID:21853124
Usp44Ratregulation of mitotic cell cycle spindle assembly checkpoint involved_inIEAUniProtKB:Q8C2S0 and ensembl:ENSMUSP000001490201600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratregulatory T cell differentiation involved_inISOUSP44 (Homo sapiens)1624291 PMID:32644293RGDPMID:32644293
Usp44Ratregulatory T cell differentiation involved_inIEAUniProtKB:Q9H0E7 and ensembl:ENSP000002584991600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp44Ratcytoplasm is_active_inIBAPANTHER:PTN002363655 and UniProtKB:Q9Y6I41600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp44Ratnucleus is_active_inISOUSP44 (Homo sapiens)1624291 PMID:32644293RGDPMID:32644293
Usp44Ratnucleus located_inIEAUniProtKB:Q8C2S0 and ensembl:ENSMUSP000001490201600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratnucleus located_inIEAUniProtKB:Q9H0E7 and ensembl:ENSP000002584991600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratnucleus located_inISOUsp44 (Mus musculus)1624291 PMID:21853124RGDPMID:21853124
Usp44Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Usp44Ratnucleus located_inISOUSP44 (Homo sapiens)1624291 PMID:20402667RGDGO_REF:0000054 and PMID:20402667

Molecular Function
1 to 15 of 15 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp44Ratcysteine-type deubiquitinase activity enablesISOUSP44 (Homo sapiens)1624291 PMID:14715245 more ...RGDPMID:14715245 more ...
Usp44Ratcysteine-type deubiquitinase activity enablesIEAEC:3.4.19.121600115GO_REF:0000003UniProtGO_REF:0000003
Usp44Ratcysteine-type deubiquitinase activity enablesIEAUniProtKB:Q9H0E7 and ensembl:ENSP000002584991600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratcysteine-type deubiquitinase activity enablesIEAInterPro:IPR001394 and InterPro:IPR0182001600115GO_REF:0000002InterProGO_REF:0000002
Usp44Ratcysteine-type deubiquitinase activity enablesIEAUniRule:UR0008807561600115GO_REF:0000104UniProtGO_REF:0000104
Usp44Ratcysteine-type peptidase activity enablesIEAUniProtKB-KW:KW-07881600115GO_REF:0000043UniProtGO_REF:0000043
Usp44Ratdeubiquitinase activity enablesIEAUniProtKB:Q9H0E7 and ensembl:ENSP000002584991600115GO_REF:0000107EnsemblGO_REF:0000107
Usp44Ratdeubiquitinase activity enablesISOUSP44 (Homo sapiens)1624291 PMID:17443180 more ...RGDPMID:17443180 more ...
Usp44Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
Usp44Ratmetal ion binding enablesIEAUniProtKB-KW:KW-04791600115GO_REF:0000043UniProtGO_REF:0000043
Usp44Ratpeptidase activity enablesIEAUniProtKB-KW:KW-06451600115GO_REF:0000043UniProtGO_REF:0000043
Usp44Ratprotein binding enablesISOUSP44 (Homo sapiens)1624291UniProtKB:P41208 more ...RGDPMID:17443180 more ...
Usp44Ratprotein binding enablesISOUsp44 (Mus musculus)1624291UniProtKB:Q99JB6 and PMID:32644293RGDPMID:32644293
Usp44Ratzinc ion binding enablesIEAInterPro:IPR0016071600115GO_REF:0000002InterProGO_REF:0000002
Usp44Ratzinc ion binding enablesIEAUniProtKB-KW:KW-08631600115GO_REF:0000043UniProtGO_REF:0000043
1 to 15 of 15 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp44Ratataxia telangiectasia-mutated (ATM) signaling pathway   ISOUSP44 (Homo sapiens)8661242 RGD 
Usp44Rathistone modification pathway   ISOUSP44 (Homo sapiens)9479061 RGD 

#
Reference Title
Reference Citation
1. H2A-DUBbing the mammalian epigenome: expanding frontiers for histone H2A deubiquitinating enzymes in cell biology and physiology. Belle JI and Nijnik A, Int J Biochem Cell Biol. 2014 May;50:161-74. doi: 10.1016/j.biocel.2014.03.004. Epub 2014 Mar 16.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Push back to respond better: regulatory inhibition of the DNA double-strand break response. Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:14715245   PMID:17443180   PMID:20402667   PMID:21853124   PMID:23187126  



Usp44
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8730,251,142 - 30,301,185 (+)NCBIGRCr8
mRatBN7.2728,364,169 - 28,412,039 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl728,364,033 - 28,410,053 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx730,354,579 - 30,400,607 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0732,516,806 - 32,562,843 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0732,294,256 - 32,340,284 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0734,714,293 - 34,759,352 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl734,744,483 - 34,759,206 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0734,773,627 - 34,818,325 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4730,898,472 - 30,971,342 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1730,965,952 - 30,991,469 (+)NCBI
Celera725,461,222 - 25,507,052 (+)NCBICelera
Cytogenetic Map7q13NCBI
USP44
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381295,516,560 - 95,551,681 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1295,516,560 - 95,551,476 (-)EnsemblGRCh38hg38GRCh38
GRCh371295,910,336 - 95,945,252 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361294,435,010 - 94,469,394 (-)NCBINCBI36Build 36hg18NCBI36
Build 341294,414,016 - 94,447,695NCBI
Celera1295,582,001 - 95,617,069 (-)NCBICelera
Cytogenetic Map12q22NCBI
HuRef1292,978,712 - 93,013,655 (-)NCBIHuRef
CHM1_11295,875,781 - 95,910,674 (-)NCBICHM1_1
T2T-CHM13v2.01295,497,607 - 95,532,730 (-)NCBIT2T-CHM13v2.0
Usp44
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391093,655,831 - 93,696,792 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1093,667,417 - 93,693,950 (+)EnsemblGRCm39 Ensembl
GRCm381093,819,969 - 93,859,425 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1093,831,555 - 93,858,088 (+)EnsemblGRCm38mm10GRCm38
MGSCv371093,294,300 - 93,311,283 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361093,261,354 - 93,278,337 (+)NCBIMGSCv36mm8
Celera1095,801,275 - 95,819,046 (+)NCBICelera
Cytogenetic Map10C2NCBI
cM Map1048.67NCBI
Usp44
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540531,977,602 - 32,006,810 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540531,977,045 - 32,006,733 (-)NCBIChiLan1.0ChiLan1.0
USP44
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210103,592,727 - 103,628,336 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112103,589,117 - 103,624,726 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01293,111,293 - 93,146,889 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11296,503,794 - 96,539,321 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1296,503,794 - 96,536,094 (-)Ensemblpanpan1.1panPan2
USP44
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11535,401,486 - 35,454,351 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1535,402,207 - 35,414,261 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1535,788,165 - 35,841,019 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01536,066,187 - 36,119,066 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1536,066,193 - 36,093,614 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11535,339,057 - 35,391,905 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01535,433,598 - 35,486,456 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01535,696,753 - 35,749,591 (-)NCBIUU_Cfam_GSD_1.0
Usp44
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494524,527,677 - 24,572,367 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650711,660,129 - 11,681,366 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650711,663,069 - 11,692,174 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP44
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl587,875,851 - 87,889,680 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1587,864,410 - 87,890,913 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2592,044,399 - 92,091,188 (+)NCBISscrofa10.2Sscrofa10.2susScr3
USP44
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11190,915,107 - 90,950,142 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1190,916,677 - 90,947,456 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037154,220,917 - 154,254,742 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp44
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475011,710,218 - 11,724,529 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475011,697,919 - 11,725,421 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Usp44
260 total Variants

Predicted Target Of
Summary Value
Count of predictions:566
Count of miRNA genes:246
Interacting mature miRNAs:294
Transcripts:ENSRNOT00000007465
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 30 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
1641885Alcrsp9Alcohol response QTL 9alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)72409960669099606Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1549840Bss5Bone structure and strength QTL 59.8femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)72475184169751841Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat

1 to 10 of 30 rows
RH139951  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2728,363,620 - 28,363,815 (+)MAPPERmRatBN7.2
Rnor_6.0734,713,719 - 34,713,913NCBIRnor6.0
Rnor_5.0734,773,053 - 34,773,247UniSTSRnor5.0
RGSC_v3.4730,897,898 - 30,898,092UniSTSRGSC3.4
Celera725,460,648 - 25,460,842UniSTS
RH 3.4 Map7193.2UniSTS
Cytogenetic Map7q13UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 9 36 91 63 62 31 25 31 6 163 83 71 34 60 31



Ensembl Acc Id: ENSRNOT00000007465   ⟹   ENSRNOP00000007465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl728,364,033 - 28,410,053 (+)Ensembl
Rnor_6.0 Ensembl734,744,483 - 34,759,206 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105243   ⟹   ENSRNOP00000089591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl728,364,033 - 28,410,053 (+)Ensembl
RefSeq Acc Id: NM_001394071   ⟹   NP_001381000
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,205 - 30,297,235 (+)NCBI
mRatBN7.2728,364,196 - 28,410,231 (+)NCBI
RefSeq Acc Id: NR_172074
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,205 - 30,297,235 (+)NCBI
mRatBN7.2728,364,196 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079054   ⟹   XP_038934982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,142 - 30,296,963 (+)NCBI
mRatBN7.2728,364,184 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079055   ⟹   XP_038934983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,171 - 30,296,963 (+)NCBI
mRatBN7.2728,364,169 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079060   ⟹   XP_038934988
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,271,336 - 30,296,963 (+)NCBI
mRatBN7.2728,384,364 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079061   ⟹   XP_038934989
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,156 - 30,296,963 (+)NCBI
mRatBN7.2728,364,200 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079063   ⟹   XP_038934991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,171 - 30,296,963 (+)NCBI
mRatBN7.2728,364,169 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_039079068   ⟹   XP_038934996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,271,379 - 30,296,963 (+)NCBI
mRatBN7.2728,384,369 - 28,410,231 (+)NCBI
RefSeq Acc Id: XM_063263444   ⟹   XP_063119514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,170 - 30,301,185 (+)NCBI
RefSeq Acc Id: XM_063263445   ⟹   XP_063119515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8730,251,168 - 30,295,729 (+)NCBI
1 to 5 of 11 rows
1 to 5 of 11 rows
Ensembl Acc Id: ENSRNOP00000007465   ⟸   ENSRNOT00000007465
RefSeq Acc Id: XP_038934991   ⟸   XM_039079063
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A942 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934983   ⟸   XM_039079055
- Peptide Label: isoform X1
- UniProtKB: D4A251 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934982   ⟸   XM_039079054
- Peptide Label: isoform X1
- UniProtKB: D4A251 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934989   ⟸   XM_039079061
- Peptide Label: isoform X1
- UniProtKB: D4A251 (UniProtKB/TrEMBL)
UBP-type   USP

Name Modeler Protein Id AA Range Protein Structure
AF-D4A251-F1-model_v2 AlphaFold D4A251 1-714 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 33 of 33 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-34382 BioCyc
Ensembl Genes ENSRNOG00000005637 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000007465 ENTREZGENE
  ENSRNOT00000007465.6 UniProtKB/TrEMBL
  ENSRNOT00000105243 ENTREZGENE
  ENSRNOT00000105243.1 UniProtKB/TrEMBL
  ENSRNOT00000124420 ENTREZGENE
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/TrEMBL
  Ub_carboxyl-term_hydrolase UniProtKB/TrEMBL
  USP_CS UniProtKB/TrEMBL
  USP_dom UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
NCBI Gene 314746 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 44 UniProtKB/TrEMBL
Pfam UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
PhenoGen Usp44 PhenoGen
PROSITE USP_1 UniProtKB/TrEMBL
  USP_2 UniProtKB/TrEMBL
  USP_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005637 RatGTEx
SMART ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
  SSF54001 UniProtKB/TrEMBL
UniProt A0A8I6A942 ENTREZGENE, UniProtKB/TrEMBL
  A6IFZ4 ENTREZGENE, UniProtKB/TrEMBL
  D4A251 ENTREZGENE, UniProtKB/TrEMBL
1 to 33 of 33 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-07 Usp44  ubiquitin specific peptidase 44  Usp44  ubiquitin specific protease 44  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Usp44  ubiquitin specific protease 44   Usp44_predicted  ubiquitin specific protease 44 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Usp44_predicted  ubiquitin specific protease 44 (predicted)      Symbol and Name status set to approved 70820 APPROVED