Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of USP12 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of USP12 mRNA | CTD | PMID:22206623 | 17beta-estradiol | affects expression | ISO | USP12 (Homo sapiens) | 6480464 | Estradiol affects the expression of USP12 mRNA | CTD | PMID:22574217 | 17beta-estradiol | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | Estradiol results in increased expression of USP12 mRNA | CTD | PMID:31614463 | 17beta-estradiol | multiple interactions | ISO | USP12 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of USP12 mRNA | CTD | PMID:20823114 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | AHR protein promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of USP12 mRNA] | CTD | PMID:19759094 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of USP12 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Usp12 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of USP12 mRNA | CTD | PMID:19759094 | 2,3,7,8-Tetrachlorodibenzofuran | affects expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2-hydroxypropanoic acid | affects expression | ISO | USP12 (Homo sapiens) | 6480464 | Lactic Acid affects the expression of USP12 mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Usp12 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of USP12 mRNA | CTD | PMID:20188158 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Usp12 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of USP12 mRNA | CTD | PMID:18648102 | aflatoxin B1 | decreases methylation | ISO | USP12 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of USP12 gene | CTD | PMID:27153756 | aflatoxin M1 | decreases expression | ISO | USP12 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of USP12 mRNA | CTD | PMID:30928695 | all-trans-retinoic acid | decreases expression | ISO | USP12 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of USP12 mRNA | CTD | PMID:33167477 | aristolochic acid A | decreases expression | ISO | USP12 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of USP12 mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | USP12 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to USP12 mRNA] | CTD | PMID:32406909 | avobenzone | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | avobenzone results in increased expression of USP12 mRNA | CTD | PMID:31016361 | benzo[a]pyrene | increases methylation | ISO | Usp12 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of USP12 exon and Benzo(a)pyrene results in increased methylation of USP12 intron | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of USP12 mRNA | CTD | PMID:25181051 | bisphenol A | decreases methylation | ISO | USP12 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of USP12 gene | CTD | PMID:31601247 | bisphenol A | increases methylation | ISO | Usp12 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of USP12 promoter | CTD | PMID:27312807 | bucladesine | multiple interactions | ISO | USP12 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of USP12 mRNA | CTD | PMID:20823114 | cisplatin | multiple interactions | ISO | USP12 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of USP12 mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | USP12 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of USP12 mRNA | CTD | PMID:27392435 | clofibrate | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of USP12 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of USP12 mRNA] | CTD | PMID:17585979 | clofibrate | increases expression | ISO | Usp12 (Mus musculus) | 6480464 | Clofibrate results in increased expression of USP12 mRNA | CTD | PMID:17585979 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of USP12 mRNA | CTD | PMID:26577399 | dicrotophos | decreases expression | ISO | USP12 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of USP12 mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of USP12 mRNA | CTD | PMID:30529165 | doxorubicin | decreases expression | ISO | USP12 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of USP12 mRNA | CTD | PMID:29803840 | ethanol | affects splicing | ISO | Usp12 (Mus musculus) | 6480464 | Ethanol affects the splicing of USP12 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of USP12 mRNA | CTD | PMID:22206623 | formaldehyde | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of USP12 mRNA | CTD | PMID:23649840 | geldanamycin | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of USP12 mRNA | CTD | PMID:26705709 | hypochlorous acid | increases expression | ISO | Usp12 (Mus musculus) | 6480464 | Hypochlorous Acid results in increased expression of USP12 mRNA | CTD | PMID:19376150 | lead(0) | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | Lead results in increased expression of USP12 mRNA | CTD | PMID:19921347 | lead(0) | affects splicing | ISO | USP12 (Homo sapiens) | 6480464 | Lead affects the splicing of USP12 mRNA | CTD | PMID:28903495 | leflunomide | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | leflunomide results in increased expression of USP12 mRNA | CTD | PMID:28988120 | lipopolysaccharide | multiple interactions | ISO | USP12 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | lipopolysaccharide | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of USP12 mRNA | CTD | PMID:35811015 | medroxyprogesterone acetate | multiple interactions | ISO | USP12 (Homo sapiens) | 6480464 | [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of USP12 mRNA | CTD | PMID:20823114 | oxycodone | decreases expression | EXP | | 6480464 | Oxycodone results in decreased expression of USP12 mRNA | CTD | PMID:23439660 | paracetamol | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of USP12 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of USP12 mRNA] | CTD | PMID:17585979 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of USP12 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of USP12 mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | ISO | USP12 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of USP12 mRNA | CTD | PMID:19159669 | pirinixic acid | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | PPARA protein affects the reaction [pirinixic acid results in decreased expression of USP12 mRNA] | CTD | PMID:21318169 | pirinixic acid | decreases expression | ISO | Usp12 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of USP12 mRNA | CTD | PMID:17426115 and PMID:21318169 | potassium chromate | decreases expression | ISO | USP12 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of USP12 mRNA | CTD | PMID:22714537 | rac-lactic acid | affects expression | ISO | USP12 (Homo sapiens) | 6480464 | Lactic Acid affects the expression of USP12 mRNA | CTD | PMID:30851411 | rotenone | decreases expression | ISO | Usp12 (Mus musculus) | 6480464 | Rotenone results in decreased expression of USP12 mRNA | CTD | PMID:23186747 | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | USP12 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | silicon dioxide | decreases expression | ISO | Usp12 (Mus musculus) | 6480464 | Silicon Dioxide results in decreased expression of USP12 mRNA | CTD | PMID:19073995 | sodium arsenite | affects methylation | ISO | USP12 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of USP12 gene | CTD | PMID:28589171 | sulforaphane | multiple interactions | ISO | Usp12 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of USP12 mRNA | CTD | PMID:30529165 | sunitinib | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of USP12 mRNA | CTD | PMID:31533062 | testosterone | decreases expression | ISO | Usp12 (Mus musculus) | 6480464 | Testosterone results in decreased expression of USP12 mRNA | CTD | PMID:21669218 | titanium dioxide | increases expression | ISO | Usp12 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of USP12 mRNA | CTD | PMID:27760801 | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of USP12 mRNA | CTD | PMID:33387578 | urethane | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | Urethane results in increased expression of USP12 mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | ISO | USP12 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of USP12 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | USP12 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of USP12 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | USP12 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of USP12 mRNA | CTD | PMID:23179753 and PMID:24935251 | vincristine | increases expression | ISO | USP12 (Homo sapiens) | 6480464 | Vincristine results in increased expression of USP12 mRNA | CTD | PMID:23649840 | vorinostat | decreases expression | ISO | USP12 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of USP12 mRNA | CTD | PMID:27188386 | |