Usp30 (ubiquitin specific peptidase 30) - Rat Genome Database

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Pathways
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Gene: Usp30 (ubiquitin specific peptidase 30) Rattus norvegicus
Analyze
Symbol: Usp30
Name: ubiquitin specific peptidase 30
RGD ID: 1307949
Description: Predicted to enable cysteine-type deubiquitinase activity and cysteine-type endopeptidase activity. Involved in negative regulation of mitophagy. Predicted to be located in mitochondrial outer membrane. Predicted to be active in cytosol and nucleus. Orthologous to human USP30 (ubiquitin specific peptidase 30); PARTICIPATES IN mitochondrial autophagy pathway; INTERACTS WITH bisphenol A; decabromodiphenyl ether; glyphosate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: deubiquitinating enzyme 30; LOC304579; ub-specific protease 30; ubiquitin carboxyl-terminal hydrolase 30; ubiquitin specific protease 30; ubiquitin thioesterase 30; ubiquitin-specific-processing protease 30
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,161,905 - 48,215,878 (-)NCBIGRCr8
mRatBN7.21242,501,345 - 42,555,311 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,501,348 - 42,555,616 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1243,668,550 - 43,692,334 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,282,141 - 44,305,925 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,342,658 - 43,366,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,262,663 - 48,316,580 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,262,658 - 48,316,722 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,044,991 - 50,068,680 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,536,736 - 43,560,425 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11243,400,118 - 43,423,920 (-)NCBI
Celera1244,105,878 - 44,129,550 (-)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (IBA,IEA)
mitochondrial outer membrane  (IEA,ISO)
mitochondrion  (ISO)
nucleus  (IBA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy. Bingol B, etal., Nature. 2014 Jun 19;510(7505):370-5. doi: 10.1038/nature13418. Epub 2014 Jun 4.
2. The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications. Durcan TM and Fon EA, Genes Dev. 2015 May 15;29(10):989-99. doi: 10.1101/gad.262758.115.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:14715245   PMID:24513856   PMID:25621951  


Genomics

Comparative Map Data
Usp30
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81248,161,905 - 48,215,878 (-)NCBIGRCr8
mRatBN7.21242,501,345 - 42,555,311 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1242,501,348 - 42,555,616 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1243,668,550 - 43,692,334 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01244,282,141 - 44,305,925 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01243,342,658 - 43,366,442 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01248,262,663 - 48,316,580 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,262,658 - 48,316,722 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01250,044,991 - 50,068,680 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41243,536,736 - 43,560,425 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11243,400,118 - 43,423,920 (-)NCBI
Celera1244,105,878 - 44,129,550 (-)NCBICelera
Cytogenetic Map12q16NCBI
USP30
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812109,023,089 - 109,088,023 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12109,023,089 - 109,088,023 (+)EnsemblGRCh38hg38GRCh38
GRCh3712109,460,894 - 109,525,828 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612107,974,774 - 108,008,570 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412107,953,110 - 107,986,902NCBI
Celera12109,114,313 - 109,149,755 (+)NCBICelera
Cytogenetic Map12q24.11NCBI
HuRef12106,508,557 - 106,544,000 (+)NCBIHuRef
CHM1_112109,458,035 - 109,493,484 (+)NCBICHM1_1
T2T-CHM13v2.012108,997,903 - 109,062,835 (+)NCBIT2T-CHM13v2.0
Usp30
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395114,238,395 - 114,261,571 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5114,203,522 - 114,262,781 (+)EnsemblGRCm39 Ensembl
GRCm385114,100,299 - 114,123,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5114,065,461 - 114,124,720 (+)EnsemblGRCm38mm10GRCm38
MGSCv375114,550,342 - 114,572,933 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365114,361,332 - 114,383,923 (+)NCBIMGSCv36mm8
Celera5111,202,052 - 111,224,786 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map555.96NCBI
Usp30
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545510,192,426 - 10,257,951 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545510,234,779 - 10,257,959 (+)NCBIChiLan1.0ChiLan1.0
USP30
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210117,118,330 - 117,153,807 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112117,114,728 - 117,150,205 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012106,629,106 - 106,664,512 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112110,022,959 - 110,058,341 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12110,022,959 - 110,058,335 (+)Ensemblpanpan1.1panPan2
USP30
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12617,918,852 - 17,981,947 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2617,919,512 - 17,981,846 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2617,819,516 - 17,882,690 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02618,263,125 - 18,326,383 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2618,263,186 - 18,325,934 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12618,028,784 - 18,091,985 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02618,253,735 - 18,317,019 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02618,272,123 - 18,335,625 (-)NCBIUU_Cfam_GSD_1.0
Usp30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118144,573,496 - 144,649,361 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936769826,615 - 904,034 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936769874,188 - 902,690 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP30
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1441,766,254 - 41,818,918 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11441,765,220 - 41,818,937 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21444,332,394 - 44,391,610 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP30
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111104,254,923 - 104,292,373 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11104,255,012 - 104,290,273 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037140,811,135 - 140,845,734 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp30
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474712,184,297 - 12,250,687 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474712,219,139 - 12,248,614 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Usp30
410 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:834
Count of miRNA genes:292
Interacting mature miRNAs:387
Transcripts:ENSRNOT00000030891
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

Markers in Region
RH134542  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21242,501,659 - 42,501,839 (+)MAPPERmRatBN7.2
Rnor_6.01248,262,975 - 48,263,154NCBIRnor6.0
Rnor_5.01250,045,303 - 50,045,482UniSTSRnor5.0
RGSC_v3.41243,537,048 - 43,537,227UniSTSRGSC3.4
Celera1244,106,190 - 44,106,369UniSTS
Cytogenetic Map12q16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 20 20 20 4 20 74 20 37 6
Low 2 23 37 21 15 21 8 11 15 4 5 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000030891   ⟹   ENSRNOP00000034698
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1242,501,348 - 42,525,037 (-)Ensembl
Rnor_6.0 Ensembl1248,262,663 - 48,286,352 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000086231   ⟹   ENSRNOP00000072669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1242,501,348 - 42,555,616 (-)Ensembl
Rnor_6.0 Ensembl1248,262,658 - 48,316,722 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109684   ⟹   ENSRNOP00000077164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1242,502,519 - 42,525,037 (-)Ensembl
RefSeq Acc Id: NM_001107153   ⟹   NP_001100623
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,161,908 - 48,185,597 (-)NCBI
mRatBN7.21242,501,348 - 42,525,037 (-)NCBI
Rnor_6.01248,262,663 - 48,286,352 (-)NCBI
Rnor_5.01250,044,991 - 50,068,680 (-)NCBI
RGSC_v3.41243,536,736 - 43,560,425 (-)RGD
Celera1244,105,878 - 44,129,550 (-)RGD
Sequence:
RefSeq Acc Id: XM_017598353   ⟹   XP_017453842
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,161,905 - 48,215,874 (-)NCBI
mRatBN7.21242,501,345 - 42,555,311 (-)NCBI
Rnor_6.01248,264,111 - 48,316,580 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039089523   ⟹   XP_038945451
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,161,905 - 48,215,878 (-)NCBI
mRatBN7.21242,501,345 - 42,555,303 (-)NCBI
RefSeq Acc Id: XM_063271397   ⟹   XP_063127467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,161,905 - 48,185,595 (-)NCBI
RefSeq Acc Id: XM_063271398   ⟹   XP_063127468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,161,905 - 48,215,874 (-)NCBI
RefSeq Acc Id: XM_063271399   ⟹   XP_063127469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,161,905 - 48,185,595 (-)NCBI
RefSeq Acc Id: XM_063271400   ⟹   XP_063127470
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,161,905 - 48,215,874 (-)NCBI
RefSeq Acc Id: XM_063271401   ⟹   XP_063127471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81248,161,905 - 48,215,874 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001100623   ⟸   NM_001107153
- UniProtKB: D3ZPG5 (UniProtKB/Swiss-Prot),   A0A8I5Y9C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453842   ⟸   XM_017598353
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K3K1 (UniProtKB/TrEMBL),   A0A8I5Y9C9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072669   ⟸   ENSRNOT00000086231
RefSeq Acc Id: ENSRNOP00000034698   ⟸   ENSRNOT00000030891
RefSeq Acc Id: XP_038945451   ⟸   XM_039089523
- Peptide Label: isoform X5
- UniProtKB: A0A8I5Y9C9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000077164   ⟸   ENSRNOT00000109684
RefSeq Acc Id: XP_063127471   ⟸   XM_063271401
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063127468   ⟸   XM_063271398
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063127470   ⟸   XM_063271400
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063127467   ⟸   XM_063271397
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063127469   ⟸   XM_063271399
- Peptide Label: isoform X4
Protein Domains
USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZPG5-F1-model_v2 AlphaFold D3ZPG5 1-517 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698716
Promoter ID:EPDNEW_R9240
Type:initiation region
Name:Usp30_1
Description:ubiquitin specific peptidase 30
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01248,286,318 - 48,286,378EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307949 AgrOrtholog
BioCyc Gene G2FUF-18938 BioCyc
Ensembl Genes ENSRNOG00000028556 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055002674 UniProtKB/Swiss-Prot
  ENSRNOG00060006083 UniProtKB/Swiss-Prot
  ENSRNOG00065006479 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000030891 ENTREZGENE
  ENSRNOT00000030891.5 UniProtKB/Swiss-Prot
  ENSRNOT00000086231.2 UniProtKB/TrEMBL
  ENSRNOT00000109684.1 UniProtKB/TrEMBL
  ENSRNOT00055004217 UniProtKB/Swiss-Prot
  ENSRNOT00060010066 UniProtKB/Swiss-Prot
  ENSRNOT00065010009 UniProtKB/Swiss-Prot
Gene3D-CATH Cysteine proteinases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_C19_UCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:304579 UniProtKB/Swiss-Prot
NCBI Gene 304579 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam UCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Usp30 PhenoGen
PROSITE USP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000028556 RatGTEx
  ENSRNOG00055002674 RatGTEx
  ENSRNOG00060006083 RatGTEx
  ENSRNOG00065006479 RatGTEx
Superfamily-SCOP SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K3K1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5Y9C9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZPG5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-04 Usp30  ubiquitin specific peptidase 30  Usp30_predicted  ubiquitin specific protease 30 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Usp30_predicted  ubiquitin specific protease 30 (predicted)      Symbol and Name status set to approved 70820 APPROVED