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Gene: Usp30 (ubiquitin specific peptidase 30) Rattus norvegicus

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Symbol:

Usp30

Name:

ubiquitin specific peptidase 30

RGD ID:

1307949

Description:

Predicted to enable cysteine-type deubiquitinase activity and cysteine-type endopeptidase activity. Involved in negative regulation of mitophagy. Predicted to be located in mitochondrial outer membrane. Predicted to be active in cytosol and nucleus. Orthologous to human USP30 (ubiquitin specific peptidase 30); PARTICIPATES IN mitochondrial autophagy pathway; INTERACTS WITH bisphenol A; decabromodiphenyl ether; glyphosate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

deubiquitinating enzyme 30; LOC304579; ub-specific protease 30; ubiquitin carboxyl-terminal hydrolase 30; ubiquitin specific protease 30; ubiquitin thioesterase 30; ubiquitin-specific-processing protease 30

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	USP30 (ubiquitin specific peptidase 30)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Mus musculus (house mouse):	Usp30 (ubiquitin specific peptidase 30)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Usp30 (ubiquitin specific peptidase 30)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	USP30 (ubiquitin specific peptidase 30)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	USP30 (ubiquitin specific peptidase 30)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Usp30 (ubiquitin specific peptidase 30)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	USP30 (ubiquitin specific peptidase 30)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	USP30 (ubiquitin specific peptidase 30)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Usp30 (ubiquitin specific peptidase 30)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	USP30 (ubiquitin specific peptidase 30)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Usp30 (ubiquitin specific peptidase 30)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	usp30 (ubiquitin specific peptidase 30)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y67D2.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Usp30	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	UBP1	Alliance	DIOPT (Hieranoid\|OrthoFinder\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	usp30	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	48,161,905 - 48,215,878 (-)	NCBI		GRCr8
mRatBN7.2	12	42,501,345 - 42,555,311 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	42,501,348 - 42,555,616 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	43,668,550 - 43,692,334 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	44,282,141 - 44,305,925 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	43,342,658 - 43,366,442 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	48,262,663 - 48,316,580 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	48,262,658 - 48,316,722 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	50,044,991 - 50,068,680 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	43,536,736 - 43,560,425 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	43,400,118 - 43,423,920 (-)	NCBI
Celera	12	44,105,878 - 44,129,550 (-)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp30	Rat	(-)-anisomycin	increases expression	ISO	USP30 (Homo sapiens)	6480464	Anisomycin results in increased expression of USP30 mRNA	CTD	PMID:24247028
Usp30	Rat	2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	ISO	Usp30 (Mus musculus)	6480464	Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to USP30 promoter]	CTD	PMID:19654925
Usp30	Rat	2,3,7,8-tetrachlorodibenzodioxine	affects expression	ISO	Usp30 (Mus musculus)	6480464	Tetrachlorodibenzodioxin affects the expression of USP30 mRNA	CTD	PMID:21570461
Usp30	Rat	4,4'-sulfonyldiphenol	decreases expression	ISO	Usp30 (Mus musculus)	6480464	bisphenol S results in decreased expression of USP30 mRNA	CTD	PMID:39298647
Usp30	Rat	acrylamide	increases expression	ISO	USP30 (Homo sapiens)	6480464	Acrylamide results in increased expression of USP30 mRNA	CTD	PMID:32763439
Usp30	Rat	aflatoxin B1	affects expression	ISO	USP30 (Homo sapiens)	6480464	Aflatoxin B1 affects the expression of USP30 protein	CTD	PMID:20106945
Usp30	Rat	aflatoxin B1	decreases expression	ISO	USP30 (Homo sapiens)	6480464	Aflatoxin B1 results in decreased expression of USP30 mRNA	CTD	PMID:22100608
Usp30	Rat	aflatoxin B1	increases expression	ISO	Usp30 (Mus musculus)	6480464	Aflatoxin B1 results in increased expression of USP30 mRNA	CTD	PMID:19770486
Usp30	Rat	antirheumatic drug	increases expression	ISO	USP30 (Homo sapiens)	6480464	Antirheumatic Agents results in increased expression of USP30 mRNA	CTD	PMID:24449571
Usp30	Rat	benzo[a]pyrene	decreases expression	ISO	USP30 (Homo sapiens)	6480464	Benzo(a)pyrene results in decreased expression of USP30 mRNA	CTD	PMID:26238291 and PMID:32234424
Usp30	Rat	benzo[a]pyrene	increases methylation	ISO	USP30 (Homo sapiens)	6480464	Benzo(a)pyrene results in increased methylation of USP30 promoter	CTD	PMID:27901495
Usp30	Rat	bis(2-ethylhexyl) phthalate	decreases expression	ISO	Usp30 (Mus musculus)	6480464	Diethylhexyl Phthalate results in decreased expression of USP30 mRNA	CTD	PMID:35550907
Usp30	Rat	bisphenol A	increases expression	EXP		6480464	bisphenol A results in increased expression of USP30 mRNA	CTD	PMID:25181051 more ...
Usp30	Rat	cadmium atom	multiple interactions	ISO	USP30 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of USP30 mRNA	CTD	PMID:35301059
Usp30	Rat	cadmium dichloride	multiple interactions	ISO	USP30 (Homo sapiens)	6480464	[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of USP30 mRNA	CTD	PMID:35301059
Usp30	Rat	carbamazepine	affects expression	ISO	USP30 (Homo sapiens)	6480464	Carbamazepine affects the expression of USP30 mRNA	CTD	PMID:25979313
Usp30	Rat	chlorpyrifos	increases expression	ISO	Usp30 (Mus musculus)	6480464	Chlorpyrifos results in increased expression of USP30 mRNA	CTD	PMID:37019170
Usp30	Rat	copper(II) sulfate	increases expression	ISO	USP30 (Homo sapiens)	6480464	Copper Sulfate results in increased expression of USP30 mRNA	CTD	PMID:19549813
Usp30	Rat	cyclosporin A	decreases expression	ISO	USP30 (Homo sapiens)	6480464	Cyclosporine results in decreased expression of USP30 mRNA	CTD	PMID:20106945 and PMID:25562108
Usp30	Rat	decabromodiphenyl ether	increases expression	EXP		6480464	decabromobiphenyl ether results in increased expression of USP30 mRNA	CTD	PMID:23914054
Usp30	Rat	deoxynivalenol	increases expression	ISO	USP30 (Homo sapiens)	6480464	deoxynivalenol results in increased expression of USP30 mRNA	CTD	PMID:24247028
Usp30	Rat	doxorubicin	decreases expression	ISO	USP30 (Homo sapiens)	6480464	Doxorubicin results in decreased expression of USP30 mRNA	CTD	PMID:29803840
Usp30	Rat	ethyl methanesulfonate	increases expression	ISO	USP30 (Homo sapiens)	6480464	Ethyl Methanesulfonate results in increased expression of USP30 mRNA	CTD	PMID:23649840
Usp30	Rat	glyphosate	increases methylation	EXP		6480464	Glyphosate results in increased methylation of USP30 gene	CTD	PMID:31011160
Usp30	Rat	manganese atom	multiple interactions	ISO	USP30 (Homo sapiens)	6480464	[manganese chloride results in increased abundance of Manganese] which results in decreased expression of USP30 mRNA	CTD	PMID:39836092
Usp30	Rat	manganese(0)	multiple interactions	ISO	USP30 (Homo sapiens)	6480464	[manganese chloride results in increased abundance of Manganese] which results in decreased expression of USP30 mRNA	CTD	PMID:39836092
Usp30	Rat	manganese(II) chloride	multiple interactions	ISO	USP30 (Homo sapiens)	6480464	[manganese chloride results in increased abundance of Manganese] which results in decreased expression of USP30 mRNA	CTD	PMID:39836092
Usp30	Rat	methyl methanesulfonate	increases expression	ISO	USP30 (Homo sapiens)	6480464	Methyl Methanesulfonate results in increased expression of USP30 mRNA	CTD	PMID:23649840
Usp30	Rat	nickel atom	decreases expression	ISO	USP30 (Homo sapiens)	6480464	Nickel results in decreased expression of USP30 mRNA	CTD	PMID:25583101
Usp30	Rat	oxaliplatin	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of USP30 mRNA	CTD	PMID:25729387
Usp30	Rat	oxaliplatin	decreases expression	EXP		6480464	oxaliplatin results in decreased expression of USP30 mRNA	CTD	PMID:25729387
Usp30	Rat	paracetamol	decreases expression	ISO	USP30 (Homo sapiens)	6480464	Acetaminophen results in decreased expression of USP30 mRNA	CTD	PMID:25704631 and PMID:29067470
Usp30	Rat	perfluorohexanesulfonic acid	decreases expression	ISO	Usp30 (Mus musculus)	6480464	perfluorohexanesulfonic acid results in decreased expression of USP30 mRNA	CTD	PMID:37995155
Usp30	Rat	sodium arsenite	increases expression	ISO	USP30 (Homo sapiens)	6480464	sodium arsenite results in increased expression of USP30 mRNA	CTD	PMID:38568856
Usp30	Rat	thioacetamide	decreases expression	EXP		6480464	Thioacetamide results in decreased expression of USP30 mRNA	CTD	PMID:34492290
Usp30	Rat	topotecan	decreases expression	EXP		6480464	Topotecan results in decreased expression of USP30 mRNA	CTD	PMID:25729387
Usp30	Rat	topotecan	multiple interactions	EXP		6480464	[oxaliplatin co-treated with Topotecan] results in decreased expression of USP30 mRNA	CTD	PMID:25729387
Usp30	Rat	trichostatin A	increases expression	ISO	USP30 (Homo sapiens)	6480464	trichostatin A results in increased expression of USP30 mRNA	CTD	PMID:24935251
Usp30	Rat	triptonide	decreases expression	ISO	Usp30 (Mus musculus)	6480464	triptonide results in decreased expression of USP30 mRNA	CTD	PMID:33045310
Usp30	Rat	urethane	decreases expression	ISO	USP30 (Homo sapiens)	6480464	Urethane results in decreased expression of USP30 mRNA	CTD	PMID:28818685
Usp30	Rat	valproic acid	increases expression	ISO	USP30 (Homo sapiens)	6480464	Valproic Acid results in increased expression of USP30 mRNA	CTD	PMID:23179753 more ...
Usp30	Rat	valproic acid	decreases expression	ISO	USP30 (Homo sapiens)	6480464	Valproic Acid results in decreased expression of USP30 mRNA	CTD	PMID:28001369
Usp30	Rat	vinclozolin	decreases expression	EXP		6480464	vinclozolin results in decreased expression of USP30 mRNA	CTD	PMID:23034163

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp30	Rat	autophagy of mitochondrion	involved_in	ISO	USP30 (Homo sapiens)	1624291	PMID:24896179 and PMID:25621951	RGD	PMID:24896179 and PMID:25621951
Usp30	Rat	autophagy of mitochondrion	involved_in	IEA	UniProtKB:Q70CQ3 and ensembl:ENSP00000257548	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	mitochondrial fusion	involved_in	ISO	Usp30 (Mus musculus)	1624291	PMID:24513856	RGD	PMID:24513856
Usp30	Rat	mitochondrial fusion	involved_in	IEA	UniProtKB:Q3UN04 and ensembl:ENSMUSP00000031588	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	negative regulation of mitophagy		IMP		13208875		RGD
Usp30	Rat	protein deubiquitination	involved_in	ISO	USP30 (Homo sapiens)	1624291	PMID:24896179	RGD	PMID:24896179
Usp30	Rat	protein deubiquitination	involved_in	IEA	UniProtKB:Q3UN04 and ensembl:ENSMUSP00000031588	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	protein deubiquitination	involved_in	IEA	UniProtKB:Q70CQ3 and ensembl:ENSP00000257548	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	protein deubiquitination	involved_in	ISO	Usp30 (Mus musculus)	1624291	PMID:24513856	RGD	PMID:24513856
Usp30	Rat	protein deubiquitination	involved_in	IEA	InterPro:IPR001394	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Usp30	Rat	protein K11-linked deubiquitination	involved_in	ISS	UniProtKB:Q70CQ3	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Usp30	Rat	protein K11-linked deubiquitination	involved_in	IEA	UniProtKB:Q70CQ3 and ensembl:ENSP00000257548	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	protein K11-linked deubiquitination	involved_in	ISO	USP30 (Homo sapiens)	1624291	PMID:25621951	RGD	PMID:25621951
Usp30	Rat	protein K6-linked deubiquitination	involved_in	ISS	UniProtKB:Q70CQ3	1600115	GO_REF:0000024	UniProt	GO_REF:0000024
Usp30	Rat	protein K6-linked deubiquitination	involved_in	IEA	UniProtKB:Q70CQ3 and ensembl:ENSP00000257548	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	protein K6-linked deubiquitination	involved_in	ISO	USP30 (Homo sapiens)	1624291	PMID:25621951	RGD	PMID:25621951
Usp30	Rat	proteolysis	involved_in	IEA	UniProtKB-KW:KW-0645	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp30	Rat	regulation of protein stability	involved_in	IBA	FB:FBgn0016756 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp30	Rat	cytosol	is_active_in	IBA	FB:FBgn0016756 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp30	Rat	membrane	located_in	IEA	UniProtKB-KW:KW-0472	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp30	Rat	mitochondrial outer membrane	located_in	ISO	USP30 (Homo sapiens)	1624291	PMID:24896179	RGD	PMID:24896179
Usp30	Rat	mitochondrial outer membrane	located_in	IEA	UniProtKB-KW:KW-1000	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp30	Rat	mitochondrial outer membrane	located_in	IEA	UniProtKB-SubCell:SL-0172	1600115	GO_REF:0000044	UniProt	GO_REF:0000044
Usp30	Rat	mitochondrial outer membrane	located_in	IEA	UniProtKB:Q70CQ3 and ensembl:ENSP00000257548	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	mitochondrion	located_in	ISO	Usp30 (Mus musculus)	1624291	PMID:24513856	RGD	PMID:24513856
Usp30	Rat	mitochondrion	located_in	IEA	UniProtKB:Q3UN04 and ensembl:ENSMUSP00000031588	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	mitochondrion	located_in	IEA	UniProtKB-KW:KW-0496	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp30	Rat	nucleus	is_active_in	IBA	FB:FBgn0016756 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp30	Rat	cysteine-type deubiquitinase activity	enables	IEA	EC:3.4.19.12	1600115	GO_REF:0000003	UniProt	GO_REF:0000003
Usp30	Rat	cysteine-type deubiquitinase activity	enables	IEA	InterPro:IPR001394 and InterPro:IPR018200	1600115	GO_REF:0000002	InterPro	GO_REF:0000002
Usp30	Rat	cysteine-type deubiquitinase activity	enables	IEA	UniProtKB:Q70CQ3 and ensembl:ENSP00000257548	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	cysteine-type deubiquitinase activity	enables	IBA	FB:FBgn0005632 more ...	1600115	GO_REF:0000033	GO_Central	GO_REF:0000033
Usp30	Rat	cysteine-type deubiquitinase activity	enables	ISO	Usp30 (Mus musculus)	1624291	PMID:24513856	RGD	PMID:24513856
Usp30	Rat	cysteine-type deubiquitinase activity	enables	IEA	UniRule:UR000880756	1600115	GO_REF:0000104	UniProt	GO_REF:0000104
Usp30	Rat	cysteine-type deubiquitinase activity	enables	IEA	UniProtKB:Q3UN04 and ensembl:ENSMUSP00000031588	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	cysteine-type deubiquitinase activity	enables	ISO	USP30 (Homo sapiens)	1624291	PMID:14715245 more ...	RGD	PMID:14715245 more ...
Usp30	Rat	cysteine-type endopeptidase activity	enables	ISO	USP30 (Homo sapiens)	1624291	PMID:24896179	RGD	PMID:24896179
Usp30	Rat	cysteine-type endopeptidase activity	enables	IEA	UniProtKB:Q70CQ3 and ensembl:ENSP00000257548	1600115	GO_REF:0000107	Ensembl	GO_REF:0000107
Usp30	Rat	cysteine-type peptidase activity	enables	IEA	UniProtKB-KW:KW-0788	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp30	Rat	hydrolase activity	enables	IEA	UniProtKB-KW:KW-0378	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp30	Rat	peptidase activity	enables	IEA	UniProtKB-KW:KW-0645	1600115	GO_REF:0000043	UniProt	GO_REF:0000043
Usp30	Rat	protein binding	enables	ISO	USP30 (Homo sapiens)	1624291	UniProtKB:P54253 more ...	RGD	PMID:32296183 and PMID:32814053
Usp30	Rat	protein binding	enables	ISO	Usp30 (Mus musculus)	1624291	UniProtKB:Q80U63 more ...	RGD	PMID:24513856

RGD Manual Annotations

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
Usp30	Rat	mitochondrial autophagy pathway		ISO	USP30 (Homo sapiens)	10401790		RGD

#	Reference Title	Reference Citation
1.	The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy.	Bingol B, etal., Nature. 2014 Jun 19;510(7505):370-5. doi: 10.1038/nature13418. Epub 2014 Jun 4.
2.	The three 'P's of mitophagy: PARKIN, PINK1, and post-translational modifications.	Durcan TM and Fon EA, Genes Dev. 2015 May 15;29(10):989-99. doi: 10.1101/gad.262758.115.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Comprehensive gene review and curation	RGD comprehensive gene curation

PMID:14715245	PMID:24513856	PMID:25621951

Usp30
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	48,161,905 - 48,215,878 (-)	NCBI		GRCr8
mRatBN7.2	12	42,501,345 - 42,555,311 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	42,501,348 - 42,555,616 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	43,668,550 - 43,692,334 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	44,282,141 - 44,305,925 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	43,342,658 - 43,366,442 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	48,262,663 - 48,316,580 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	48,262,658 - 48,316,722 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	50,044,991 - 50,068,680 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	43,536,736 - 43,560,425 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	12	43,400,118 - 43,423,920 (-)	NCBI
Celera	12	44,105,878 - 44,129,550 (-)	NCBI		Celera
Cytogenetic Map	12	q16	NCBI

USP30
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	12	109,023,089 - 109,088,023 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	12	109,023,089 - 109,088,023 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	12	109,460,894 - 109,525,828 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	12	107,974,774 - 108,008,570 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	12	107,953,110 - 107,986,902	NCBI
Celera	12	109,114,313 - 109,149,755 (+)	NCBI		Celera
Cytogenetic Map	12	q24.11	NCBI
HuRef	12	106,508,557 - 106,544,000 (+)	NCBI		HuRef
CHM1_1	12	109,458,035 - 109,493,484 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	12	108,997,903 - 109,062,835 (+)	NCBI		T2T-CHM13v2.0

Usp30
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	114,238,395 - 114,261,571 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	114,203,522 - 114,262,781 (+)	Ensembl		GRCm39 Ensembl
GRCm38	5	114,100,299 - 114,123,510 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	114,065,461 - 114,124,720 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	114,550,342 - 114,572,933 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	114,361,332 - 114,383,923 (+)	NCBI		MGSCv36	mm8
Celera	5	111,202,052 - 111,224,786 (+)	NCBI		Celera
Cytogenetic Map	5	F	NCBI
cM Map	5	55.96	NCBI

Usp30
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955455	10,192,426 - 10,257,951 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955455	10,234,779 - 10,257,959 (+)	NCBI	ChiLan1.0	ChiLan1.0

USP30
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	10	117,118,330 - 117,153,807 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	12	117,114,728 - 117,150,205 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	12	106,629,106 - 106,664,512 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	12	110,022,959 - 110,058,341 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	12	110,022,959 - 110,058,335 (+)	Ensembl	panpan1.1		panPan2

USP30
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	17,918,852 - 17,981,947 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	17,919,512 - 17,981,846 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	17,819,516 - 17,882,690 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	18,263,125 - 18,326,383 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	18,263,186 - 18,325,934 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	18,028,784 - 18,091,985 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	18,253,735 - 18,317,019 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	18,272,123 - 18,335,625 (-)	NCBI		UU_Cfam_GSD_1.0

Usp30
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	144,573,496 - 144,649,361 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936769	826,615 - 904,034 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936769	874,188 - 902,690 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

USP30
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	41,766,254 - 41,818,918 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	41,765,220 - 41,818,937 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	44,332,394 - 44,391,610 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

USP30
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	11	104,254,923 - 104,292,373 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	11	104,255,012 - 104,290,273 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666037	140,811,135 - 140,845,734 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Usp30
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	12,184,297 - 12,250,687 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	12,219,139 - 12,248,614 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants in Usp30
410 total Variants

Predicted Target Of

	Summary Value
Count of predictions:	834
Count of miRNA genes:	292
Interacting mature miRNAs:	387
Transcripts:	ENSRNOT00000030891
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631560	Apr1	Acute phase response QTL 1	6.1		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	19144362	46669029	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
8693635	Alc28	Alcohol consumption QTL 28	2.7	0.439	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	23081340	44726024	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411643	Foco20	Food consumption QTL 20		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	20328819	46669029	Rat
61324	Eae5	Experimental allergic encephalomyelitis QTL 5	14		nervous system integrity trait (VT:0010566)	percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)	12	19610870	46669029	Rat
5684888	Pia42	Pristane induced arthritis QTL 42			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	19610870	42828880	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	13182736	46669029	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	13198157	46669029	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	12812385	46669029	Rat
1300162	Bp188	Blood pressure QTL 188	3.19		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	32103174	45899022	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	13182736	46669029	Rat
1600386	Calcic2	Intracellular calcium level QTL 2		0.001	platelet physiology trait (VT:0005464)	platelet intracellular calcium level (CMO:0000922)	12	28064433	46669029	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	12351619	46669029	Rat
1300175	Cm5	Cardiac mass QTL 5	3.78		heart mass (VT:0007028)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	28064433	45899022	Rat
8693658	Alc33	Alcohol consumption QTL 33	2.1	0.68	drinking behavior trait (VT:0001422)	calculated ethanol drink intake rate (CMO:0001615)	12	23081340	43551788	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	45055165	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	12812385	46669029	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat

RH134542

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	12	42,501,659 - 42,501,839 (+)	MAPPER	mRatBN7.2
Rnor_6.0	12	48,262,975 - 48,263,154	NCBI	Rnor6.0
Rnor_5.0	12	50,045,303 - 50,045,482	UniSTS	Rnor5.0
RGSC_v3.4	12	43,537,048 - 43,537,227	UniSTS	RGSC3.4
Celera	12	44,106,190 - 44,106,369	UniSTS
Cytogenetic Map	12	q16	UniSTS

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31


RefSeq Transcripts	NM_001107153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769337	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039089523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271397	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271398	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063271401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC131519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC134141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473973	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000030891 ⟹ ENSRNOP00000034698

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	42,501,348 - 42,525,037 (-)	Ensembl
Rnor_6.0 Ensembl	12	48,262,663 - 48,286,352 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000086231 ⟹ ENSRNOP00000072669

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	42,501,348 - 42,555,616 (-)	Ensembl
Rnor_6.0 Ensembl	12	48,262,658 - 48,316,722 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000109684 ⟹ ENSRNOP00000077164

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	42,502,519 - 42,525,037 (-)	Ensembl

RefSeq Acc Id:

NM_001107153 ⟹ NP_001100623

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,161,908 - 48,185,597 (-)	NCBI
mRatBN7.2	12	42,501,348 - 42,525,037 (-)	NCBI
Rnor_6.0	12	48,262,663 - 48,286,352 (-)	NCBI
Rnor_5.0	12	50,044,991 - 50,068,680 (-)	NCBI
RGSC_v3.4	12	43,536,736 - 43,560,425 (-)	RGD
Celera	12	44,105,878 - 44,129,550 (-)	RGD

Sequence:

show sequence

CCGCCGAAGCGGGGTCGCCACCGCGGGTTCCTCCACTTTGGGAACCTCGCACACTGGGCTCCTCATTACATTACGCTGCAGCGGGCGTGGGGGGCGGCGGCTGGCGGCGGCGGCAGTGGCCGGGATGC
TGAGTTCCCGGGCGCAGGCGGCGAGGACAGCGGCCGACAAGGCCCTCCAGCGCTTCCTGCGCACCGGGGCGGCTGTCAGATACAAAGTCATGAAGAACTGGGGAGTGATCGGTGGAATTGCTGCTGCT
CTTGCAGCAGGAATATATGTTATCTGGGGTCCCATTACAGAGAGGAAGAAGCGGAGAAAAGGGCTTGTGCCTGGCCTTGTCAACTTGGGGAACACCTGCTTCATGAACTCCCTGCTGCAGGGTTTGTC
TGCCTGCCCCGCGTTTGTCAAGTGGCTGGAGGAGTTTACCACCCAGTACTCCAGGGACCAGCAGGGGCCGCACACACACCAGTGCCTGTCCTTGACACTGCTGAGCCTCCTGAAAGCTCTGTCCTGCC
AAGAAGTCACTGAGGAAGAGGTCTTGGACGCCAGCTGCCTGCTGGACGTCCTGAGAATGTACCGGTGGCAGATCTCGTCCTTTGAGGAGCAGGATGCTCACGAACTGTTCCATGTCATCACCTCATCC
CTGGAGGACGAGCGGGACCGCCAGCCTCGGGTCACCCACTTGTTTGATGTGCACTCCCTGGAGCAGCAGTCAGAAATGGCTCCCAGACAAGTCACCTGCCACACGAGAGGGTCCCCTCACCCCACGAC
CAATCCCTGGAAGTCTCAGCACCCCTTCCATGGGAGGCTCAGCAGTAACATGGTGTGCAAGCACTGTGAGCACCAGAGCCCTGTTCGGTTTGACACCTTTGATAGCCTTTCCCTCAGTATTCCAGCTG
CTACTTGGGGGCACCCACTGACACTGGACCACTGCCTTCACCACTTCATCTCATCCGAGTCGGTGCGAGACGTTGTGTGTGACAACTGTACAAAGATTGAAGCAAAAGGGACCCAGAACGGGGAAAAG
GTGGAGCACCAGAGGACCACTTTCGTTAAACAGTTAAAGCTAGGAAAGCTGCCACAGTGCCTCTGCATCCACCTGCAGCGGCTCAGCTGGTCCAGCCAAGGCACGCCCTTGAAGCGGCATGAGCACGT
GCAATTTAACGAGTTCCTGATGATGGACTTCTACAAGTACCGCCTCCTGGGACATAAACCCAGCCAGCATGGCCCCAAAGCCACTGAGAGCCCAGGGTCTGCCCTGGGAGTACAGGACACACAGGCGG
CCCCGAAGCCAGGTCTGAGTCAGCCAGCGGCCCCCAAGACACAGTTTTTTATGAATGGCGCCTGCTCCCCGTCTTTGTTGCCAGCCCTGCCTTCTCCGATGGCTTTCCCTCTACCAGTGGCTCCTGAC
TACAGCTCCTCCATGTACCTCTTCCGCTTGATGGCAGTTGTCGTCCACCATGGAGACATGCACTCTGGACACTTTGTCACCTACAGACGGTCACCACCTTCTGCCAAGAACCCTCTCTCAACCAGCAA
CCAGTGGCTGTGGATTTCCGATGACACTGTCCGAAAGGCCAGCCTGCAGGAGGTCCTGTCCTCTAGTGCCTACCTGCTGTTCTATGAGCGAGTTCTGTCCAGGGTGCAGCAGCAGGGGCGAGAGTACA
GGTCAGAGGAGTGACAGGCCAGCCCAGAGCCAGGGCCCTCGGCGAGGTCCACACGTCCAGGATAAAAGCAAAGGCATGCCACGTGTACACGTGCAAGCCAGCCCTCCAGAGCCCTCAGCCTCTGTATT
CTGAGAGCAGGCTCCACTGGGAGCCAGTCCCACAGCGCTGCCAGGGTGACCTGGAAGATGTCCTTTTGTGTCTGTGGAGCCTCTTCCTTGACACAGGCAATTAAAACCGCCAGATCCCAGAAGCCCCC
TTTTCTGTGCTGTCATTGCTAGGTGTTCTCGGACGGCCGCCTTTGGCTGACTCCCTGACATTTCACCATAGATCTTTATTTTTAATAAGGAGGCCCATAAATATTATTGACAAGAATTAGTGAATTAT
TAAAGGCAACAATTGAGAAGAAAAAGTGCCTTTGTTTCCAGTTGTTCTGAGACCAAGCATGACCTAAGAGTCACAGGCGAGAGGCTGAGAAAGCCCTGTCCTTCCAGGCTCCTCAGAGGCCAGAACAG
TTCAAGGATGCCTGAGACAGCGCCAGCTCGCTCACACCGGAACCCCAGCATGTAGAGAGACTGAGGCAGGAGGATCACTGCAACTTCCAGGCCAGCCAGGGCTCCTTAATTAAAACCTTGTCTCCTCC
CCTAAGCCTCGAGAACACCTACCTACCTTTGGGTGTGCCTTTTGTGATCTTCAGTTCTGTGTTATCAAGGTCATTTGCCAAGCTCACACTGGATGAGGGGAAAGCCTCTTCCTGAGCCTGTCACCTGC
ACTGCTGGTGGCTACACAAGGTTGCTCTCTTCATGTTATTGCCCACAACAGGATTTGCAGAGCTTGGGCAGGGCCACCTGAAAGCTGGCACTAACCCAGGGCCGCGGTCTCTCTGGACCTTGCTTTCT
CAGCCCACAGTGCGGAAGAAAGCAGTGTGATGTTTGGACAGAAGTGTAGCAGGTGCGTCCTTCAGGCGTCAGGGCCGCACTCTGTCTCTTTCTCTCGTGACCTCTCGGTAAGCAGAAGGTACACTGGG
CCTCTTCCCTTTCCAGACAAGCCTCATGAACAGCCAGGCACAGAGGAATCCGTGTTAGCTAAGTGTGTAATTTAGAAAAAATGATACCAAACTCAAACTGACTCTTCTGGTCTAAGATTGGGAACCAG
ACCTATCCAAAGGTCACTGAGGTAAGACTAGACCGTGTTTTCTTCGCTGGGGTGAGCTGGCAGAGATTCCAGATGTGCCTCCGTCAGCTATGAGATCAGGTCTCACTGTGCATCCTGAGGACTCGAGA
CTATGCAGTGCTGGACCGCCACACCACAGCAGCCCCACACAGCAGACCTGGCTTTCGAGCTGAGATGAACACAAAAGAGGTCAGTGGCTGTAACCCTAGAGCACTGTGCAGGGCTGTGGGCCCCAGCG
AGAAGAGAGGTGGCCAAGAGGAAAGTGTGCAAGGCTGCTCAGTCGCCGCTGTGAGCCCAGGCTGTAGATGTGTCAGCCTGCGCGAGCGCTAATGTCCTTCCTCATGTTGTAAATTATTACAGTAGATA
GTGACCAATGATGGTTCCTAGTTTTAAGTTATTCACAGTAGGTATCTTCTTCCTGGAGAAACTTAAGTTAAGCTAGTATTTACGCTGTAGGCTGCTGAGTGTGGATTTGCTAAAGCATTTGTATCTGC
TGTGTACTATTGCAATAAAGATGGTTTTGTTAGG

hide sequence

RefSeq Acc Id:

XM_017598353 ⟹ XP_017453842

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,161,905 - 48,215,874 (-)	NCBI
mRatBN7.2	12	42,501,345 - 42,555,311 (-)	NCBI
Rnor_6.0	12	48,264,111 - 48,316,580 (-)	NCBI

Sequence:

show sequence

TTCACCACCCTGGAGACAGAAGTAGATGTGACCGGGATGGCCAGGGTGACCTCCCGATGGCCTT
GCTGCAGGACTTTCCCACCCGAGGCAGATACAAAGTCATGAAGAACTGGGGAGTGATCGGTGGAATTGCTGCTGCTCTTGCAGCAGGAATATATGTTATCTGGGGTCCCATTACAGAGAGGAAGAAGC
GGAGAAAAGGGCTTGTGCCTGGCCTTGTCAACTTGGGGAACACCTGCTTCATGAACTCCCTGCTGCAGGGTTTGTCTGCCTGCCCCGCGTTTGTCAAGTGGCTGGAGGAGTTTACCACCCAGTACTCC
AGGGACCAGCAGGGGCCGCACACACACCAGTGCCTGTCCTTGACACTGCTGAGCCTCCTGAAAGCTCTGTCCTGCCAAGAAGTCACTGAGGAAGAGGTCTTGGACGCCAGCTGCCTGCTGGACGTCCT
GAGAATGTACCGGTGGCAGATCTCGTCCTTTGAGGAGCAGGATGCTCACGAACTGTTCCATGTCATCACCTCATCCCTGGAGGACGAGCGGGACCGCCAGCCTCGGGTCACCCACTTGTTTGATGTGC
ACTCCCTGGAGCAGCAGTCAGAAATGGCTCCCAGACAAGTCACCTGCCACACGAGAGGGTCCCCTCACCCCACGACCAATCCCTGGAAGTCTCAGCACCCCTTCCATGGGAGGCTCAGCAGTAACATG
GTGTGCAAGCACTGTGAGCACCAGAGCCCTGTTCGGTTTGACACCTTTGATAGCCTTTCCCTCAGTATTCCAGCTGCTACTTGGGGGCACCCACTGACACTGGACCACTGCCTTCACCACTTCATCTC
ATCCGAGTCGGTGCGAGACGTTGTGTGTGACAACTGTACAAAGATTGAAGCAAAAGGGACCCAGAACGGGGAAAAGGTGGAGCACCAGAGGACCACTTTCGTTAAACAGTTAAAGCTAGGAAAGCTGC
CACAGTGCCTCTGCATCCACCTGCAGCGGCTCAGCTGGTCCAGCCAAGGCACGCCCTTGAAGCGGCATGAGCACGTGCAATTTAACGAGTTCCTGATGATGGACTTCTACAAGTACCGCCTCCTGGGA
CATAAACCCAGCCAGCATGGCCCCAAAGCCACTGAGAGCCCAGGGTCTGCCCTGGGAGTACAGGACACACAGGCGGCCCCGAAGCCAGGTCTGAGTCAGCCAGCGGCCCCCAAGACACAGTTTTTTAT
GAATGGCGCCTGCTCCCCGTCTTTGTTGCCAGCCCTGCCTTCTCCGATGGCTTTCCCTCTACCAGTGGCTCCTGACTACAGCTCCTCCATGTACCTCTTCCGCTTGATGGCAGTTGTCGTCCACCATG
GAGACATGCACTCTGGACACTTTGTCACCTACAGACGGTCACCACCTTCTGCCAAGAACCCTCTCTCAACCAGCAACCAGTGGCTGTGGATTTCCGATGACACTGTCCGAAAGGCCAGCCTGCAGGAG
GTCCTGTCCTCTAGTGCCTACCTGCTGTTCTATGAGCGAGTTCTGTCCAGGGTGCAGCAGCAGGGGCGAGAGTACAGGTCAGAGGAGTGACAGGCCAGCCCAGAGCCAGGGCCCTCGGCGAGGTCCAC
ACGTCCAGGATAAAAGCAAAGGCATGCCACGTGTACACGTGCAAGCCAGCCCTCCAGAGCCCTCAGCCTCTGTATTCTGAGAGCAGGCTCCACTGGGAGCCAGTCCCACAGCGCTGCCAGGGTGACCT
GGAAGATGTCCTTTTGTGTCTGTGGAGCCTCTTCCTTGACACAGGCAATTAAAACCGCCAGATCCCAGAA

hide sequence

RefSeq Acc Id:

XM_039089523 ⟹ XP_038945451

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,161,905 - 48,215,878 (-)	NCBI
mRatBN7.2	12	42,501,345 - 42,555,303 (-)	NCBI

RefSeq Acc Id:

XM_063271397 ⟹ XP_063127467

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,161,905 - 48,185,595 (-)	NCBI

RefSeq Acc Id:

XM_063271398 ⟹ XP_063127468

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,161,905 - 48,215,874 (-)	NCBI

RefSeq Acc Id:

XM_063271399 ⟹ XP_063127469

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,161,905 - 48,185,595 (-)	NCBI

RefSeq Acc Id:

XM_063271400 ⟹ XP_063127470

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,161,905 - 48,215,874 (-)	NCBI

RefSeq Acc Id:

XM_063271401 ⟹ XP_063127471

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	48,161,905 - 48,215,874 (-)	NCBI


Protein RefSeqs	NP_001100623	(Get FASTA)	NCBI Sequence Viewer
	XP_017453842	(Get FASTA)	NCBI Sequence Viewer
	XP_038945451	(Get FASTA)	NCBI Sequence Viewer
	XP_063127467	(Get FASTA)	NCBI Sequence Viewer
	XP_063127468	(Get FASTA)	NCBI Sequence Viewer
	XP_063127469	(Get FASTA)	NCBI Sequence Viewer
	XP_063127470	(Get FASTA)	NCBI Sequence Viewer
	XP_063127471	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	D3ZPG5	(Get FASTA)	NCBI Sequence Viewer
	EDM13952	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000034698
	ENSRNOP00000034698.4
	ENSRNOP00000072669
	ENSRNOP00000077164

RefSeq Acc Id:

NP_001100623 ⟸ NM_001107153

- UniProtKB:

D3ZPG5 (UniProtKB/Swiss-Prot), A0A8I5Y9C9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSSRAQAARTAADKALQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLSLLKALS
CQEVTEEEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEMAPRQVTCHTRGSPHPTTNPWKSQHPFHGRLSSNMVCKHCEHQSPVRFDTFDSLSLSIP
AATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTQNGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSQGTPLKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKATESPGSALGVQDTQ
AAPKPGLSQPAAPKTQFFMNGACSPSLLPALPSPMAFPLPVAPDYSSSMYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAKNPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGRE
YRSEE

hide sequence

RefSeq Acc Id:	XP_017453842 ⟸ XM_017598353
- Peptide Label:	isoform X2
- UniProtKB:	A0A0G2K3K1 (UniProtKB/TrEMBL), A0A8I5Y9C9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALLQDFPTRGRYKVMKNWGVIGGIAAALAAGIYVIWGPITERKKRRKGLVPGLVNLGNTCFMN SLLQGLSACPAFVKWLEEFTTQYSRDQQGPHTHQCLSLTLLSLLKALSCQEVTEEEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQPRVTHLFDVHSLEQQSEMAPRQVTCHTR GSPHPTTNPWKSQHPFHGRLSSNMVCKHCEHQSPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTQNGEKVEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSQGTP LKRHEHVQFNEFLMMDFYKYRLLGHKPSQHGPKATESPGSALGVQDTQAAPKPGLSQPAAPKTQFFMNGACSPSLLPALPSPMAFPLPVAPDYSSSMYLFRLMAVVVHHGDMHSGHFVTYRRSPPSAK NPLSTSNQWLWISDDTVRKASLQEVLSSSAYLLFYERVLSRVQQQGREYRSEE hide sequence

Ensembl Acc Id:

ENSRNOP00000072669 ⟸ ENSRNOT00000086231

Ensembl Acc Id:

ENSRNOP00000034698 ⟸ ENSRNOT00000030891

RefSeq Acc Id:	XP_038945451 ⟸ XM_039089523
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I5Y9C9 (UniProtKB/TrEMBL)

Protein Domains

USP

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZPG5-F1-model_v2	AlphaFold	D3ZPG5	1-517	view protein structure

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

RGD ID:

13698716

Promoter ID:

EPDNEW_R9240

Type:

initiation region

Name:

Usp30_1

Description:

ubiquitin specific peptidase 30

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	12	48,286,318 - 48,286,378	EPDNEW

Database	Acc Id	Source(s)
BioCyc Gene	G2FUF-18938	BioCyc
Ensembl Genes	ENSRNOG00000028556	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000030891	ENTREZGENE
	ENSRNOT00000030891.5	UniProtKB/Swiss-Prot
	ENSRNOT00000086231	ENTREZGENE
	ENSRNOT00000109684	ENTREZGENE
Gene3D-CATH	Cysteine proteinases	UniProtKB/Swiss-Prot
InterPro	Papain-like_cys_pep_sf	UniProtKB/Swiss-Prot
	Peptidase_C19	UniProtKB/Swiss-Prot
	Peptidase_C19_UCH	UniProtKB/Swiss-Prot
	USP_CS	UniProtKB/Swiss-Prot
	USP_dom	UniProtKB/Swiss-Prot
KEGG Report	rno:304579	UniProtKB/Swiss-Prot
NCBI Gene	304579	ENTREZGENE
PANTHER	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE	UniProtKB/Swiss-Prot
	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 30	UniProtKB/Swiss-Prot
Pfam	UCH	UniProtKB/Swiss-Prot
PhenoGen	Usp30	PhenoGen
PROSITE	USP_1	UniProtKB/Swiss-Prot
	USP_2	UniProtKB/Swiss-Prot
	USP_3	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000028556	RatGTEx
Superfamily-SCOP	SSF54001	UniProtKB/Swiss-Prot
UniProt	A0A0G2K3K1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5Y9C9	ENTREZGENE, UniProtKB/TrEMBL
	D3ZPG5	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-04	Usp30	ubiquitin specific peptidase 30	Usp30_predicted	ubiquitin specific protease 30 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Usp30_predicted	ubiquitin specific protease 30 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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