Usp16 (ubiquitin specific peptidase 16) - Rat Genome Database

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Gene: Usp16 (ubiquitin specific peptidase 16) Rattus norvegicus
Analyze
Symbol: Usp16
Name: ubiquitin specific peptidase 16
RGD ID: 1307192
Description: Predicted to enable several functions, including peptidase activity; ribosomal small subunit binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including monoubiquitinated protein deubiquitination; positive regulation of macromolecule biosynthetic process; and positive regulation of ribosome biogenesis. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Orthologous to human USP16 (ubiquitin specific peptidase 16); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; histone modification pathway; INTERACTS WITH (+)-schisandrin B; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: deubiquitinating enzyme 16; LOC288306; ubiquitin carboxyl-terminal hydrolase 16; ubiquitin specific protease 16; ubiquitin thioesterase 16; ubiquitin thiolesterase 16; ubiquitin-specific-processing protease 16
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81140,166,651 - 40,196,792 (+)NCBIGRCr8
mRatBN7.21126,681,359 - 26,711,313 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1126,681,414 - 26,710,539 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1135,379,429 - 35,408,496 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01128,079,674 - 28,108,749 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01127,268,609 - 27,297,684 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,101,213 - 27,130,345 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,101,227 - 27,130,341 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01130,726,656 - 30,755,793 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41127,204,766 - 27,233,883 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11127,204,765 - 27,233,883 (+)NCBI
Celera1126,433,856 - 26,462,887 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 57 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp16Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of USP16 mRNA]CTDPMID:31150632
Usp16Rat1,2-dimethylhydrazine decreases expressionISOUsp16 (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of USP16 mRNACTDPMID:22206623
Usp16Rat17alpha-ethynylestradiol affects expressionISOUsp16 (Mus musculus)6480464Ethinyl Estradiol affects the expression of USP16 mRNACTDPMID:17555576
Usp16Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionISOUsp16 (Mus musculus)6480464Tetrachlorodibenzodioxin affects the expression of USP16 mRNACTDPMID:21570461
Usp16Rat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of USP16 mRNACTDPMID:21346803
Usp16Rat2-hydroxypropanoic acid decreases expressionISOUSP16 (Homo sapiens)6480464Lactic Acid results in decreased expression of USP16 mRNACTDPMID:30851411
Usp16Rat3-chloropropane-1,2-diol increases expressionEXP 6480464alpha-Chlorohydrin results in increased expression of USP16 proteinCTDPMID:34915118
Usp16Rat3-hydroxyisovaleric acid increases expressionEXP 6480464beta-hydroxyisovaleric acid results in increased expression of USP16 mRNACTDPMID:24124592
Usp16Rat4,4'-sulfonyldiphenol increases expressionISOUsp16 (Mus musculus)6480464bisphenol S results in increased expression of USP16 mRNACTDPMID:39298647
Usp16Rataristolochic acid A decreases expressionISOUSP16 (Homo sapiens)6480464aristolochic acid I results in decreased expression of USP16 mRNACTDPMID:33212167
Usp16Ratbenzene decreases expressionISOUSP16 (Homo sapiens)6480464Benzene results in decreased expression of USP16 mRNACTDPMID:15929907
Usp16Ratbenzo[a]pyrene decreases expressionISOUsp16 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of USP16 mRNACTDPMID:22641617
Usp16Ratbeta-lapachone decreases expressionISOUSP16 (Homo sapiens)6480464beta-lapachone results in decreased expression of USP16 mRNACTDPMID:38218311
Usp16Ratbis(2-ethylhexyl) phthalate decreases expressionISOUsp16 (Mus musculus)6480464Diethylhexyl Phthalate results in decreased expression of USP16 mRNACTDPMID:33754040
Usp16Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of USP16 mRNACTDPMID:25181051
Usp16Ratbisphenol A decreases expressionISOUSP16 (Homo sapiens)6480464bisphenol A results in decreased expression of USP16 mRNACTDPMID:29275510
Usp16Ratcadmium dichloride increases expressionISOUSP16 (Homo sapiens)6480464Cadmium Chloride results in increased expression of USP16 mRNACTDPMID:26472689
Usp16RatCGP 52608 multiple interactionsISOUSP16 (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to USP16 gene]CTDPMID:28238834
Usp16Ratchlordecone decreases expressionISOUsp16 (Mus musculus)6480464Chlordecone results in decreased expression of USP16 mRNACTDPMID:33711761
Usp16Ratchlorpyrifos decreases expressionISOUsp16 (Mus musculus)6480464Chlorpyrifos results in decreased expression of USP16 mRNACTDPMID:37019170

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Biological Process
1 to 20 of 37 rows

  
Object Symbol
Species
Term
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Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp16Ratbiological_process  ND 159840710/2014: no relevant rat dataRGD 
Usp16Ratcell division involved_inIEAUniProtKB-KW:KW-01321600115GO_REF:0000043UniProtGO_REF:0000043
Usp16Ratchromatin organization involved_inIEAUniProtKB-KW:KW-01561600115GO_REF:0000043UniProtGO_REF:0000043
Usp16Ratchromatin remodeling involved_inIEAGO:01409501600115GO_REF:0000108GOCGO_REF:0000108
Usp16RatDNA damage response involved_inISOUSP16 (Homo sapiens)1624291 PMID:20550933RGDPMID:20550933
Usp16RatDNA damage response involved_inIEAUniProtKB:Q9Y5T5 and ensembl:ENSP000003828581600115GO_REF:0000107EnsemblGO_REF:0000107
Usp16RatDNA damage response involved_inISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Ratmitotic cell cycle involved_inIEAUniRule:UR0001608941600115GO_REF:0000104UniProtGO_REF:0000104
Usp16Ratmitotic nuclear division involved_inIEAUniRule:UR0001608941600115GO_REF:0000104UniProtGO_REF:0000104
Usp16Ratmonoubiquitinated protein deubiquitination involved_inISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Ratmonoubiquitinated protein deubiquitination involved_inIEAUniProtKB:Q9Y5T5 and ensembl:ENSP000003828581600115GO_REF:0000107EnsemblGO_REF:0000107
Usp16Ratmonoubiquitinated protein deubiquitination involved_inISOUSP16 (Homo sapiens)1624291 PMID:32129764RGDPMID:32129764
Usp16Ratpositive regulation of DNA-templated transcription involved_inISOUSP16 (Homo sapiens)1624291 PMID:17914355RGDPMID:17914355
Usp16Ratpositive regulation of DNA-templated transcription involved_inIEAUniRule:UR0001608941600115GO_REF:0000104UniProtGO_REF:0000104
Usp16Ratpositive regulation of DNA-templated transcription involved_inIEAUniProtKB:Q9Y5T5 and ensembl:ENSP000003828581600115GO_REF:0000107EnsemblGO_REF:0000107
Usp16Ratpositive regulation of DNA-templated transcription involved_inIBAMGI:1921362 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Usp16Ratpositive regulation of DNA-templated transcription involved_inISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Ratpositive regulation of ribosome biogenesis involved_inISOUSP16 (Homo sapiens)1624291 PMID:32129764RGDPMID:32129764
Usp16Ratpositive regulation of ribosome biogenesis involved_inISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Ratpositive regulation of ribosome biogenesis involved_inIEAUniProtKB:Q9Y5T5 and ensembl:ENSP000003828581600115GO_REF:0000107EnsemblGO_REF:0000107
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Cellular Component
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Object Symbol
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Reference
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Source
Original Reference(s)
Usp16Ratcytoplasm is_active_inISOUSP16 (Homo sapiens)1624291 PMID:32129764RGDPMID:32129764
Usp16Ratcytoplasm is_active_inISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Ratcytoplasm is_active_inIEAUniProtKB:Q9Y5T5 and ensembl:ENSP000003828581600115GO_REF:0000107EnsemblGO_REF:0000107
Usp16Ratnucleus located_inISOUSP16 (Homo sapiens)1624291 PMID:17914355RGDPMID:17914355
Usp16Ratnucleus located_inIEAUniProtKB-SubCell:SL-01911600115GO_REF:0000044UniProtGO_REF:0000044
Usp16Ratnucleus located_inIEAUniProtKB:Q9Y5T5 and ensembl:ENSP000003828581600115GO_REF:0000107EnsemblGO_REF:0000107
Usp16Ratnucleus located_inISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Ratnucleus located_inIEAUniProtKB-KW:KW-05391600115GO_REF:0000043UniProtGO_REF:0000043
Usp16Ratnucleus located_inIEAUniRule:UR0001608941600115GO_REF:0000104UniProtGO_REF:0000104
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Molecular Function
1 to 20 of 43 rows

  
Object Symbol
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Reference
Notes
Source
Original Reference(s)
Usp16Ratcysteine-type deubiquitinase activity enablesISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Ratcysteine-type deubiquitinase activity enablesIEAUniRule:UR0001608941600115GO_REF:0000104UniProtGO_REF:0000104
Usp16Ratcysteine-type deubiquitinase activity enablesIEAInterPro:IPR001394 more ...1600115GO_REF:0000002InterProGO_REF:0000002
Usp16Ratcysteine-type deubiquitinase activity enablesIEAUniProtKB:Q9Y5T5 and ensembl:ENSP000003828581600115GO_REF:0000107EnsemblGO_REF:0000107
Usp16Ratcysteine-type deubiquitinase activity enablesIEAEC:3.4.19.121600115GO_REF:0000003UniProtGO_REF:0000003
Usp16Ratcysteine-type deubiquitinase activity enablesISOUSP16 (Homo sapiens)1624291 PMID:17914355 and PMID:32129764RGDPMID:17914355 and PMID:32129764
Usp16Ratcysteine-type endopeptidase activity enablesISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Ratcysteine-type endopeptidase activity enablesIEAUniProtKB:Q9Y5T5 and ensembl:ENSP000003828581600115GO_REF:0000107EnsemblGO_REF:0000107
Usp16Ratcysteine-type endopeptidase activity enablesIEAUniRule:UR0001608941600115GO_REF:0000104UniProtGO_REF:0000104
Usp16Ratcysteine-type endopeptidase activity enablesISOUSP16 (Homo sapiens)1624291 PMID:17914355RGDPMID:17914355
Usp16Ratcysteine-type peptidase activity enablesIEAUniProtKB-KW:KW-07881600115GO_REF:0000043UniProtGO_REF:0000043
Usp16Rathistone binding enablesISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Rathistone binding enablesIEAUniRule:UR0001608941600115GO_REF:0000104UniProtGO_REF:0000104
Usp16Rathistone binding enablesIEAUniProtKB:Q9Y5T5 and ensembl:ENSP000003828581600115GO_REF:0000107EnsemblGO_REF:0000107
Usp16Rathistone binding enablesISOUSP16 (Homo sapiens)1624291 PMID:17914355RGDPMID:17914355
Usp16Rathistone H2A deubiquitinase activity enablesISOUSP16 (Homo sapiens)1624291 PMID:20550933RGDPMID:20550933
Usp16Rathistone H2A deubiquitinase activity enablesIEAUniProtKB:Q99LG0 and ensembl:ENSMUSP000000267101600115GO_REF:0000107EnsemblGO_REF:0000107
Usp16Rathistone H2A deubiquitinase activity enablesISOUsp16 (Mus musculus)1624291 PMID:24034696RGDPMID:24034696
Usp16Rathistone H2A deubiquitinase activity enablesISSUniProtKB:Q99LG01600115GO_REF:0000024UniProtGO_REF:0000024
Usp16Rathistone H2A deubiquitinase activity enablesISSUniProtKB:Q9Y5T51600115GO_REF:0000024UniProtGO_REF:0000024
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RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Usp16Ratataxia telangiectasia-mutated (ATM) signaling pathway   ISOUSP16 (Homo sapiens)8661242 RGD 
Usp16Rathistone modification pathway   ISOUSP16 (Homo sapiens)9479061 RGD 

#
Reference Title
Reference Citation
1. H2A-DUBbing the mammalian epigenome: expanding frontiers for histone H2A deubiquitinating enzymes in cell biology and physiology. Belle JI and Nijnik A, Int J Biochem Cell Biol. 2014 May;50:161-74. doi: 10.1016/j.biocel.2014.03.004. Epub 2014 Mar 16.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Push back to respond better: regulatory inhibition of the DNA double-strand break response. Panier S and Durocher D, Nat Rev Mol Cell Biol. 2013 Oct;14(10):661-72. doi: 10.1038/nrm3659. Epub 2013 Sep 4.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
PMID:8889548   PMID:12477932   PMID:17512543   PMID:17914355   PMID:20550933   PMID:24034696  



Usp16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81140,166,651 - 40,196,792 (+)NCBIGRCr8
mRatBN7.21126,681,359 - 26,711,313 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1126,681,414 - 26,710,539 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1135,379,429 - 35,408,496 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01128,079,674 - 28,108,749 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01127,268,609 - 27,297,684 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01127,101,213 - 27,130,345 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1127,101,227 - 27,130,341 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01130,726,656 - 30,755,793 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41127,204,766 - 27,233,883 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11127,204,765 - 27,233,883 (+)NCBI
Celera1126,433,856 - 26,462,887 (+)NCBICelera
Cytogenetic Map11q11NCBI
USP16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382129,024,668 - 29,054,488 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2129,024,629 - 29,054,488 (+)EnsemblGRCh38hg38GRCh38
GRCh372130,396,989 - 30,426,809 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362129,318,809 - 29,348,680 (+)NCBINCBI36Build 36hg18NCBI36
Build 342129,318,808 - 29,348,676NCBI
Celera2115,580,416 - 15,610,282 (+)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2115,803,158 - 15,833,022 (+)NCBIHuRef
CHM1_12129,959,294 - 29,989,158 (+)NCBICHM1_1
T2T-CHM13v2.02127,388,120 - 27,417,933 (+)NCBIT2T-CHM13v2.0
Usp16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391687,251,833 - 87,280,403 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1687,251,591 - 87,280,405 (+)EnsemblGRCm39 Ensembl
GRCm381687,454,985 - 87,483,515 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1687,454,703 - 87,483,517 (+)EnsemblGRCm38mm10GRCm38
MGSCv371687,455,230 - 87,483,760 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361687,344,252 - 87,372,711 (+)NCBIMGSCv36mm8
Celera1687,647,825 - 87,678,084 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1649.54NCBI
Usp16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540728,375,246 - 28,413,279 (+)NCBIChiLan1.0ChiLan1.0
USP16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22225,205,924 - 25,238,276 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12120,065,075 - 20,096,751 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02115,455,805 - 15,487,853 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12128,843,680 - 28,876,267 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2128,843,749 - 28,876,267 (+)Ensemblpanpan1.1panPan2
USP16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13124,034,399 - 24,060,268 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3124,034,448 - 24,059,874 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3124,027,524 - 24,053,526 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03124,148,182 - 24,173,976 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3124,148,255 - 24,173,879 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13124,098,633 - 24,124,438 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03124,100,335 - 24,126,234 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03124,571,759 - 24,597,559 (+)NCBIUU_Cfam_GSD_1.0
Usp16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497124,478,812 - 24,504,012 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650012,964,122 - 12,989,152 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650012,963,811 - 12,989,024 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13192,376,881 - 192,406,468 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113192,376,850 - 192,406,474 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213202,679,050 - 202,708,992 (+)NCBISscrofa10.2Sscrofa10.2susScr3
USP16
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1263,170,677 - 63,201,257 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl263,170,979 - 63,201,445 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660715,755,732 - 5,786,317 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp16
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474517,006,175 - 17,028,952 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474517,005,020 - 17,029,220 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Usp16
157 total Variants

Predicted Target Of
Summary Value
Count of predictions:20
Count of miRNA genes:15
Interacting mature miRNAs:18
Transcripts:ENSRNOT00000002173
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 12 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat

1 to 10 of 12 rows
RH130565  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21126,710,291 - 26,710,506 (+)MAPPERmRatBN7.2
Rnor_6.01127,130,094 - 27,130,308NCBIRnor6.0
Rnor_5.01130,755,542 - 30,755,756UniSTSRnor5.0
RGSC_v3.41127,233,632 - 27,233,846UniSTSRGSC3.4
Celera1126,462,636 - 26,462,850UniSTS
RH 3.4 Map11134.9UniSTS
Cytogenetic Map11q11UniSTS
RH133685  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21126,710,581 - 26,710,761 (+)MAPPERmRatBN7.2
Rnor_6.01127,130,384 - 27,130,563NCBIRnor6.0
Rnor_5.01130,755,832 - 30,756,011UniSTSRnor5.0
RGSC_v3.41127,233,922 - 27,234,101UniSTSRGSC3.4
Celera1126,462,926 - 26,463,105UniSTS
RH 3.4 Map11123.8UniSTS
Cytogenetic Map11q11UniSTS
AI072090  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81140,196,270 - 40,196,563 (+)Marker Load Pipeline
mRatBN7.21126,710,021 - 26,710,314 (+)MAPPERmRatBN7.2
Rnor_6.01127,129,824 - 27,130,116NCBIRnor6.0
Rnor_5.01130,755,272 - 30,755,564UniSTSRnor5.0
RGSC_v3.41127,233,362 - 27,233,654UniSTSRGSC3.4
Celera1126,462,366 - 26,462,658UniSTS
RH 3.4 Map11140.4UniSTS
Cytogenetic Map11q11UniSTS
RH137401  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21126,705,609 - 26,705,814 (+)MAPPERmRatBN7.2
Rnor_6.01127,125,412 - 27,125,616NCBIRnor6.0
Rnor_5.01130,750,860 - 30,751,064UniSTSRnor5.0
RGSC_v3.41127,228,950 - 27,229,154UniSTSRGSC3.4
Celera1126,457,953 - 26,458,157UniSTS
RH 3.4 Map11136.7UniSTS
Cytogenetic Map11q11UniSTS
Usp16  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21126,704,647 - 26,704,899 (+)MAPPERmRatBN7.2
Rnor_6.01127,124,450 - 27,124,701NCBIRnor6.0
Rnor_5.01130,749,898 - 30,750,149UniSTSRnor5.0
RGSC_v3.41127,227,988 - 27,228,239UniSTSRGSC3.4
Celera1126,456,991 - 26,457,242UniSTS
Cytogenetic Map11q11UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000002173   ⟹   ENSRNOP00000002173
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1126,681,414 - 26,710,539 (+)Ensembl
Rnor_6.0 Ensembl1127,101,227 - 27,130,341 (+)Ensembl
RefSeq Acc Id: NM_001100501   ⟹   NP_001093971
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81140,167,666 - 40,196,792 (+)NCBI
mRatBN7.21126,681,414 - 26,710,543 (+)NCBI
Rnor_6.01127,101,227 - 27,130,345 (+)NCBI
Rnor_5.01130,726,656 - 30,755,793 (+)NCBI
RGSC_v3.41127,204,766 - 27,233,883 (+)RGD
Celera1126,433,856 - 26,462,887 (+)RGD
Sequence:
RefSeq Acc Id: XM_006248015   ⟹   XP_006248077
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81140,167,630 - 40,196,603 (+)NCBI
mRatBN7.21126,681,359 - 26,711,313 (+)NCBI
Rnor_6.01127,101,214 - 27,130,345 (+)NCBI
Rnor_5.01130,726,656 - 30,755,793 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063270433   ⟹   XP_063126503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81140,166,651 - 40,196,603 (+)NCBI
RefSeq Acc Id: XM_063270434   ⟹   XP_063126504
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81140,166,651 - 40,196,603 (+)NCBI
RefSeq Acc Id: XM_063270435   ⟹   XP_063126505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81140,183,306 - 40,196,603 (+)NCBI
RefSeq Acc Id: XR_010055944
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81140,167,627 - 40,196,203 (+)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_001093971 (Get FASTA)   NCBI Sequence Viewer  
  XP_006248077 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126503 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126504 (Get FASTA)   NCBI Sequence Viewer  
  XP_063126505 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI12387 (Get FASTA)   NCBI Sequence Viewer  
  EDM10641 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000002173
  ENSRNOP00000002173.5
GenBank Protein Q2KJ09 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_001093971   ⟸   NM_001100501
- UniProtKB: Q2KJ09 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006248077   ⟸   XM_006248015
- Peptide Label: isoform X3
- UniProtKB: Q2KJ09 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002173   ⟸   ENSRNOT00000002173
RefSeq Acc Id: XP_063126503   ⟸   XM_063270433
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063126504   ⟸   XM_063270434
- Peptide Label: isoform X2
USP

Name Modeler Protein Id AA Range Protein Structure
AF-Q2KJ09-F1-model_v2 AlphaFold Q2KJ09 1-826 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13698023
Promoter ID:EPDNEW_R8547
Type:initiation region
Name:Usp16_1
Description:ubiquitin specific peptidase 16
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01127,101,253 - 27,101,313EPDNEW


1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-22052 BioCyc
Ensembl Genes ENSRNOG00000001598 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002173 ENTREZGENE
  ENSRNOT00000002173.7 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.40.10 UniProtKB/Swiss-Prot
  Cysteine proteinases UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7315796 IMAGE-MGC_LOAD
  IMAGE:7934674 IMAGE-MGC_LOAD
InterPro Papain-like_cys_pep_sf UniProtKB/Swiss-Prot
  Peptidase_C19 UniProtKB/Swiss-Prot
  Peptidase_C19_UCH UniProtKB/Swiss-Prot
  UBP16 UniProtKB/Swiss-Prot
  USP_CS UniProtKB/Swiss-Prot
  USP_dom UniProtKB/Swiss-Prot
  Znf_RING/FYVE/PHD UniProtKB/Swiss-Prot
  Znf_UBP UniProtKB/Swiss-Prot
KEGG Report rno:288306 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105608 IMAGE-MGC_LOAD
  MGC:124708 IMAGE-MGC_LOAD
NCBI Gene 288306 ENTREZGENE
PANTHER UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot
  UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UniProtKB/Swiss-Prot
Pfam UCH UniProtKB/Swiss-Prot
  zf-UBP UniProtKB/Swiss-Prot
PhenoGen Usp16 PhenoGen
PROSITE USP_1 UniProtKB/Swiss-Prot
  USP_2 UniProtKB/Swiss-Prot
  USP_3 UniProtKB/Swiss-Prot
  ZF_UBP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001598 RatGTEx
SMART ZnF_UBP UniProtKB/Swiss-Prot
Superfamily-SCOP RING/U-box UniProtKB/Swiss-Prot
  SSF54001 UniProtKB/Swiss-Prot
UniProt Q2KJ09 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Usp16  ubiquitin specific peptidase 16    ubiquitin specific protease 16  Name updated 1299863 APPROVED
2005-12-06 Usp16  ubiquitin specific protease 16  Usp16_predicted  ubiquitin specific protease 16 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Usp16_predicted  ubiquitin specific protease 16 (predicted)      Symbol and Name status set to approved 70820 APPROVED