Mgst3 (microsomal glutathione S-transferase 3) - Rat Genome Database

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Gene: Mgst3 (microsomal glutathione S-transferase 3) Rattus norvegicus
Analyze
Symbol: Mgst3
Name: microsomal glutathione S-transferase 3
RGD ID: 1306373
Description: Enables glutathione peroxidase activity. Involved in response to organonitrogen compound. Predicted to be located in mitochondrial outer membrane. Predicted to be active in endoplasmic reticulum and nuclear envelope. Orthologous to human MGST3 (microsomal glutathione S-transferase 3); PARTICIPATES IN glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: glutathione S-transferase 3, mitochondrial; LOC289197
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81382,059,480 - 82,080,418 (-)NCBIGRCr8
mRatBN7.21379,526,541 - 79,547,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,526,541 - 79,547,411 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,156,415 - 82,177,230 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,463,504 - 83,484,105 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,701,212 - 80,722,001 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,601,499 - 85,622,392 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,601,499 - 85,622,314 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01390,244,188 - 90,265,081 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41383,038,049 - 83,058,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11383,052,236 - 83,073,033 (-)NCBI
Celera1379,231,777 - 79,252,592 (-)NCBICelera
Cytogenetic Map13q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitrole  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (ISO)
artesunate  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
bifenthrin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
buta-1,3-diene  (ISO)
butylated hydroxyanisole  (ISO)
cadmium dichloride  (EXP)
calciol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
cholic acid  (ISO)
ciguatoxin CTX1B  (ISO)
clofibrate  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
coumarin  (EXP)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diazinon  (EXP)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP,ISO)
dinophysistoxin 1  (ISO)
diquat  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
ethoxyquin  (ISO)
fenofibrate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
genistein  (EXP,ISO)
glafenine  (EXP)
hydrogen peroxide  (ISO)
inulin  (ISO)
isoflavones  (ISO)
ivermectin  (ISO)
leflunomide  (EXP,ISO)
maneb  (ISO)
manganese(II) chloride  (EXP)
methapyrilene  (EXP)
methimazole  (EXP)
methylmercury chloride  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
nefazodone  (EXP)
nickel atom  (EXP)
nimesulide  (EXP)
nitrofen  (EXP)
nitrogen dioxide  (ISO)
okadaic acid  (ISO)
oltipraz  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
PhIP  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP,ISO)
propiconazole  (EXP)
pyrazinecarboxamide  (EXP)
Rebamipide  (EXP)
resveratrol  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
sulindac  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Molecular and catalytic properties of three rat leukotriene C(4) synthase homologs. Schroder O, etal., Biochem Biophys Res Commun. 2003 Dec 12;312(2):271-6.
7. The role of glutathione-S-transferase in anti-cancer drug resistance. Townsend DM and Tew KD, Oncogene 2003 Oct 20;22(47):7369-75.
8. Sodium nitroprusside regulates mRNA expressions of LTC4 synthesis enzymes in hepatic ischemia/reperfusion injury rats via NF-kappaB signaling pathway. Yang SL, etal., Pharmacology. 2007;80(1):11-20. Epub 2007 May 10.
Additional References at PubMed
PMID:9278457   PMID:19946888   PMID:21700703   PMID:23376485  


Genomics

Comparative Map Data
Mgst3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81382,059,480 - 82,080,418 (-)NCBIGRCr8
mRatBN7.21379,526,541 - 79,547,479 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1379,526,541 - 79,547,411 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1382,156,415 - 82,177,230 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01383,463,504 - 83,484,105 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01380,701,212 - 80,722,001 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01385,601,499 - 85,622,392 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1385,601,499 - 85,622,314 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01390,244,188 - 90,265,081 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41383,038,049 - 83,058,802 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11383,052,236 - 83,073,033 (-)NCBI
Celera1379,231,777 - 79,252,592 (-)NCBICelera
Cytogenetic Map13q24NCBI
MGST3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,631,234 - 165,656,136 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,631,213 - 165,661,796 (+)EnsemblGRCh38hg38GRCh38
GRCh371165,600,471 - 165,625,373 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,867,074 - 163,891,481 (+)NCBINCBI36Build 36hg18NCBI36
Build 341162,332,107 - 162,356,511NCBI
Celera1138,705,621 - 138,730,025 (+)NCBICelera
Cytogenetic Map1q24.1NCBI
HuRef1136,847,571 - 136,872,857 (+)NCBIHuRef
CHM1_11167,022,686 - 167,047,957 (+)NCBICHM1_1
T2T-CHM13v2.01164,977,647 - 165,002,573 (+)NCBIT2T-CHM13v2.0
Mgst3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391167,199,535 - 167,221,410 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1167,199,535 - 167,221,410 (-)EnsemblGRCm39 Ensembl
GRCm381167,371,966 - 167,393,841 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1167,371,966 - 167,393,841 (-)EnsemblGRCm38mm10GRCm38
MGSCv371169,302,515 - 169,323,928 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361169,209,059 - 169,230,472 (-)NCBIMGSCv36mm8
Celera1169,789,931 - 169,811,361 (-)NCBICelera
Cytogenetic Map1H2.3NCBI
cM Map174.76NCBI
Mgst3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546211,024,789 - 11,031,282 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546211,024,678 - 11,041,851 (-)NCBIChiLan1.0ChiLan1.0
MGST3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2184,110,120 - 84,137,066 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1183,778,739 - 83,805,682 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01141,063,051 - 141,087,563 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11144,852,428 - 144,876,800 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1144,868,059 - 144,876,684 (+)Ensemblpanpan1.1panPan2
MGST3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13817,670,329 - 17,691,822 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3817,668,752 - 17,718,704 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3817,726,881 - 17,748,346 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03817,724,958 - 17,751,927 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3817,724,911 - 17,778,579 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13817,723,864 - 17,745,307 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03818,075,030 - 18,096,456 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03818,369,309 - 18,390,981 (-)NCBIUU_Cfam_GSD_1.0
Mgst3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344101,807,586 - 101,819,050 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648119,654,441 - 19,659,291 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648119,654,335 - 19,665,994 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MGST3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl485,069,607 - 85,094,981 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1485,069,603 - 85,095,022 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2492,725,520 - 92,750,937 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MGST3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12563,227,351 - 63,252,547 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2563,224,338 - 63,252,340 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605564,986,997 - 65,012,877 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mgst3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248263,969,929 - 3,987,159 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248263,969,838 - 3,987,159 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mgst3
98 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:36
Interacting mature miRNAs:39
Transcripts:ENSRNOT00000005719
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133124133193395974Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133453521879535218Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133726209282262092Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133737450982374509Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133741558480753406Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133741558482415584Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)133843340883433408Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133975454484754544Rat
12879444Bp397Blood pressure QTL 397arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134504940490049404Rat
12879471Bp398Blood pressure QTL 398arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134551471990514719Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)134569998390699983Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134619797684753113Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)135987440885581182Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)136906051986800898Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)136906051986800898Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)136906051986800898Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)137402391880753406Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)137486211785581182Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 8 8 8
Medium 3 43 49 33 19 33 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000005719   ⟹   ENSRNOP00000005719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1379,526,541 - 79,547,411 (-)Ensembl
Rnor_6.0 Ensembl1385,601,499 - 85,622,314 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097875   ⟹   ENSRNOP00000089717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1379,526,541 - 79,532,869 (-)Ensembl
RefSeq Acc Id: NM_001191594   ⟹   NP_001178523
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81382,059,480 - 82,080,295 (-)NCBI
mRatBN7.21379,526,541 - 79,547,356 (-)NCBI
Rnor_6.01385,601,499 - 85,622,314 (-)NCBI
Rnor_5.01390,244,188 - 90,265,081 (-)NCBI
Celera1379,231,777 - 79,252,592 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250209   ⟹   XP_006250271
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81382,059,480 - 82,080,418 (-)NCBI
mRatBN7.21379,526,541 - 79,547,479 (-)NCBI
Rnor_6.01385,601,499 - 85,622,392 (-)NCBI
Rnor_5.01390,244,188 - 90,265,081 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090502   ⟹   XP_038946430
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81382,059,480 - 82,080,026 (-)NCBI
mRatBN7.21379,526,541 - 79,547,086 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001178523 (Get FASTA)   NCBI Sequence Viewer  
  XP_006250271 (Get FASTA)   NCBI Sequence Viewer  
  XP_038946430 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM09282 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000005719
  ENSRNOP00000005719.4
  ENSRNOP00000089717
  ENSRNOP00000089717.1
RefSeq Acc Id: NP_001178523   ⟸   NM_001191594
- UniProtKB: D4ADS4 (UniProtKB/TrEMBL),   A6IDL5 (UniProtKB/TrEMBL),   A0A8I6AAX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250271   ⟸   XM_006250209
- Peptide Label: isoform X1
- UniProtKB: D4ADS4 (UniProtKB/TrEMBL),   A6IDL5 (UniProtKB/TrEMBL),   A0A8I6AAX9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000005719   ⟸   ENSRNOT00000005719
RefSeq Acc Id: XP_038946430   ⟸   XM_039090502
- Peptide Label: isoform X1
- UniProtKB: D4ADS4 (UniProtKB/TrEMBL),   A6IDL5 (UniProtKB/TrEMBL),   A0A8I6AAX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000089717   ⟸   ENSRNOT00000097875

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4ADS4-F1-model_v2 AlphaFold D4ADS4 1-152 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698974
Promoter ID:EPDNEW_R9499
Type:multiple initiation site
Name:Mgst3_1
Description:microsomal glutathione S-transferase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01385,622,352 - 85,622,412EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306373 AgrOrtholog
BioCyc Gene G2FUF-17520 BioCyc
BioCyc Pathway PWY-4061 [glutathione-mediated detoxification I] BioCyc
  PWY-7112 [4-hydroxy-2-nonenal detoxification] BioCyc
BioCyc Pathway Image PWY-4061 BioCyc
  PWY-7112 BioCyc
Ensembl Genes ENSRNOG00000004245 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000005719 ENTREZGENE
  ENSRNOT00000005719.8 UniProtKB/TrEMBL
  ENSRNOT00000097875 ENTREZGENE
  ENSRNOT00000097875.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.550 UniProtKB/TrEMBL
InterPro MAPEG-like_dom UniProtKB/TrEMBL
  Membr-assoc_MAPEG UniProtKB/TrEMBL
KEGG Report rno:289197 UniProtKB/TrEMBL
NCBI Gene 289197 ENTREZGENE
PANTHER MICROSOMAL GLUTATHIONE S-TRANSFERASE UniProtKB/TrEMBL
  MICROSOMAL GLUTATHIONE S-TRANSFERASE 3 UniProtKB/TrEMBL
Pfam MAPEG UniProtKB/TrEMBL
PhenoGen Mgst3 PhenoGen
RatGTEx ENSRNOG00000004245 RatGTEx
Superfamily-SCOP SSF161084 UniProtKB/TrEMBL
UniProt A0A8I6AAX9 ENTREZGENE, UniProtKB/TrEMBL
  A6IDL5 ENTREZGENE, UniProtKB/TrEMBL
  D4ADS4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Mgst3  microsomal glutathione S-transferase 3   Mgst3_predicted  microsomal glutathione S-transferase 3 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Mgst3_predicted  microsomal glutathione S-transferase 3 (predicted)      Symbol and Name status set to approved 70820 APPROVED