Dpep2 (dipeptidase 2) - Rat Genome Database

Name: Dpep2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Dpep2 (dipeptidase 2) Rattus norvegicus

Analyze

Symbol:

Dpep2

Name:

dipeptidase 2

RGD ID:

1305746

Description:

Predicted to enable dipeptidase activity. Predicted to be involved in leukotriene D4 catabolic process. Predicted to be located in membrane. Orthologous to human DPEP2 (dipeptidase 2); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 3,3',4,4',5-pentachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC291984

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DPEP2 (dipeptidase 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Dpep2 (dipeptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DPEP2 (dipeptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LOC489748 (dipeptidase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DPEP2 (dipeptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DPEP2 (dipeptidase 2)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	DPEP3 (dipeptidase 3)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	DPEP2 (dipeptidase 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Mus musculus (house mouse):	Dpep2 (dipeptidase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dpep2 (dipeptidase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG6154	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG42750	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG44837	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	CG5282	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	dpep2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	50,795,322 - 50,806,320 (-)	NCBI		GRCr8
mRatBN7.2	19	33,883,557 - 33,896,487 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	33,885,478 - 33,891,954 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	40,701,008 - 40,707,443 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	41,354,322 - 41,360,757 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	43,653,038 - 43,659,469 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	37,964,098 - 37,975,154 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	37,964,105 - 37,970,537 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	48,831,084 - 48,851,920 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	35,832,224 - 35,838,659 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	35,837,105 - 35,843,540 (-)	NCBI
Celera	19	33,313,021 - 33,319,456 (-)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal dominant dyskeratosis congenita 6 (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (EXP)

acrylamide (EXP)

aldehydo-D-glucose (ISO)

amphetamine (EXP)

benzo[a]pyrene (EXP,ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

D-glucose (ISO)

dextran sulfate (ISO)

diuron (ISO)

fulvestrant (ISO)

gentamycin (EXP)

glucose (ISO)

lidocaine (EXP)

manganese(II) chloride (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (EXP)

nickel atom (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP)

sodium arsenite (ISO)

testosterone (EXP)

titanium dioxide (ISO)

topotecan (EXP)

tributylstannane (EXP)

triptonide (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

leukotriene D4 catabolic process (IEA,ISO,ISS)

leukotriene metabolic process (ISO,ISS)

proteolysis (IEA)

Cellular Component

membrane (ISO,ISS)

side of membrane (IEA)

Molecular Function

dipeptidase activity (ISO,ISS)

exopeptidase activity (ISO)

metal ion binding (IEA)

metallodipeptidase activity (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:12738806	PMID:15489334

Genomics

Comparative Map Data

Dpep2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	19	50,795,322 - 50,806,320 (-)	NCBI		GRCr8
mRatBN7.2	19	33,883,557 - 33,896,487 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	33,885,478 - 33,891,954 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	40,701,008 - 40,707,443 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	19	41,354,322 - 41,360,757 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	19	43,653,038 - 43,659,469 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	19	37,964,098 - 37,975,154 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	37,964,105 - 37,970,537 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	48,831,084 - 48,851,920 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	35,832,224 - 35,838,659 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	19	35,837,105 - 35,843,540 (-)	NCBI
Celera	19	33,313,021 - 33,319,456 (-)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

DPEP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	67,987,390 - 68,000,619 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	16	67,987,394 - 68,000,586 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	68,021,293 - 68,034,522 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	66,578,798 - 66,590,857 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	16	66,578,800 - 66,590,857	NCBI
Celera	16	52,529,750 - 52,541,821 (-)	NCBI		Celera
Cytogenetic Map	16	q22.1	NCBI
HuRef	16	53,894,885 - 53,907,048 (-)	NCBI		HuRef
CHM1_1	16	69,429,363 - 69,441,488 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	16	73,783,178 - 73,796,408 (-)	NCBI		T2T-CHM13v2.0

Dpep2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	106,711,577 - 106,732,658 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	106,711,577 - 106,723,055 (-)	Ensembl		GRCm39 Ensembl
GRCm39 Ensembl	8	106,711,576 - 106,718,391 (-)	Ensembl		GRCm39 Ensembl
GRCm38	8	105,984,945 - 106,006,026 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	105,984,944 - 105,991,759 (-)	Ensembl	GRCm38		mm10	GRCm38
GRCm38.p6 Ensembl	8	105,984,945 - 105,996,423 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	108,508,957 - 108,520,323 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	108,874,186 - 108,885,552 (-)	NCBI		MGSCv36	mm8
Celera	8	110,213,109 - 110,224,474 (-)	NCBI		Celera
Cytogenetic Map	8	D3	NCBI
cM Map	8	53.07	NCBI

DPEP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	18	77,510,359 - 77,526,862 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	16	83,421,784 - 83,438,196 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	48,328,281 - 48,341,510 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	67,715,805 - 67,729,164 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	67,715,805 - 67,729,164 (-)	Ensembl	panpan1.1		panPan2

LOC489748
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	81,517,919 - 81,522,098 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	81,518,072 - 81,522,075 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	81,508,182 - 81,512,060 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	81,953,364 - 81,957,393 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	81,953,204 - 81,957,389 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	81,779,586 - 81,783,615 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	81,461,884 - 81,465,762 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	82,104,060 - 82,107,938 (+)	NCBI		UU_Cfam_GSD_1.0

DPEP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	28,593,546 - 28,599,051 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	28,593,542 - 28,599,076 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	26,020,128 - 26,025,817 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DPEP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	59,439,237 - 59,447,400 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	59,440,951 - 59,447,698 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	22,172,991 - 22,187,738 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Dpep2
68 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	37
Count of miRNA genes:	35
Interacting mature miRNAs:	36
Transcripts:	ENSRNOT00000034722
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590298	Uminl5	Urine mineral level QTL 5	3.59	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	19	1	36824771	Rat
8552935	Pigfal10	Plasma insulin-like growth factor 1 level QTL 10	5.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	19	1	36824771	Rat
9590250	Scort11	Serum corticosterone level QTL 11	23.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	19	1	36824771	Rat
9590090	Insglur8	Insulin/glucose ratio QTL 8	10.81	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	19	1	36824771	Rat
9589102	Slep13	Serum leptin concentration QTL 13	4.63	0.001	blood leptin amount (VT:0005667)	plasma leptin level (CMO:0000781)	19	569374	45569374	Rat
8694186	Bw152	Body weight QTL 152	3.34	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	569374	45569374	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2187927	46708701	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2187927	56457239	Rat
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	2316121	47316121	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	3204777	48204777	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	4096155	55283277	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	7457249	42983518	Rat
724565	Tcas5	Tongue tumor susceptibility QTL 5	10.04		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	19	9977753	39654489	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10827970	43544039	Rat
1558656	Prcs1	Prostate cancer susceptibility QTL 1	5		prostate integrity trait (VT:0010571)	percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)	19	15114598	34521833	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	15455860	57337602	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	15605023	46559041	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	15630201	57337602	Rat
2298478	Eau8	Experimental allergic uveoretinitis QTL 8		0.0163	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	19	17154433	57337602	Rat
61350	Bp32	Blood pressure QTL 32		0.012	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	19	20483575	57337602	Rat
1549835	Tcas7	Tongue tumor susceptibility QTL 7		0.001	tongue integrity trait (VT:0010553)	squamous cell carcinoma of the head and neck tumor number (CMO:0001876)	19	24817978	39654489	Rat
1354600	Salc2	Saline consumption QTL 2	9.91	0.001	drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	19	27530207	37947399	Rat
1354607	Gmadr1	Adrenal mass QTL 1	5.83		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	19	27530207	37947399	Rat
1354633	Bw28	Body weight QTL 28	6.04		body mass (VT:0001259)	body weight (CMO:0000012)	19	27530207	37947399	Rat
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	29322490	57337602	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum insulin level (CMO:0000358)	19	33838214	55283146	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	19	33838214	55283146	Rat

Markers in Region

RH141644

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	33,885,597 - 33,885,778 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	37,964,222 - 37,964,402	NCBI	Rnor6.0
Rnor_5.0	19	48,831,208 - 48,831,388	UniSTS	Rnor5.0
RGSC_v3.4	19	35,832,344 - 35,832,524	UniSTS	RGSC3.4
Celera	19	33,313,141 - 33,313,321	UniSTS
RH 3.4 Map	19	317.7	UniSTS
Cytogenetic Map	19	q12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium			2	2	11	2				4	8	11
Low	3	43	55	39	8	39	8	11	26	31	31		8
Below cutoff									47		2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001011928	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008772487	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005496638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005496639	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121465	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC088195	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000019	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000034722 ⟹ ENSRNOP00000031955

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	33,885,478 - 33,891,954 (-)	Ensembl
Rnor_6.0 Ensembl	19	37,964,105 - 37,970,537 (-)	Ensembl

RefSeq Acc Id:

NM_001011928 ⟹ NP_001011928

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,795,322 - 50,801,757 (-)	NCBI
mRatBN7.2	19	33,885,478 - 33,891,913 (-)	NCBI
Rnor_6.0	19	37,964,102 - 37,970,537 (-)	NCBI
Rnor_5.0	19	48,831,084 - 48,851,920 (-)	NCBI
RGSC_v3.4	19	35,832,224 - 35,838,659 (-)	RGD
Celera	19	33,313,021 - 33,319,456 (-)	RGD

Sequence:

show sequence

GTGCCTGGTCTGAGGAACTCATACATCTGACCCAGCTTCCACAGTAAGGTTTTCGCGACCCTCA
TCCGTGCCGGTTTGCTCTGCACTGAGCAAGATGTCACTCAAGGGCCTCGAGGGTCATTGGGTGC
TTAGCCAAGTGTTCCTGTTGGTGGTGGTGCTGCTGCTGTTAGGGCCCTCAGAACCTCTAATAAG
GGCCCAGACAAAACCAGGCATCGCTGATGCTTCCACTGCACCAAGCCCCCTCAGAACACTCACC
AAGCCTGCCATCTTCAGCATTCCAACCACTCCTGGCAACCCCAATTTCCCAGACCTGCGAGATC
GCACCAGAGCCCTGATGCAGGACTTCCCGCTTATAGATGGCCACAATGACCTGCCTCTTGTTCT
GAGGCAATTTTACCAGAATGGACTACAAGATACTAACCTGAGAAACTTCACCCATGGCCAGACC
AGCCTGAATAGGCTTAAAGATGGCTTTGTGGGAGCCCAGTTCTGGTCTGCTTACGTGCCGTGCC
AGACCCAGGACCGGGATGCCCTGCGTCTCACACTGGAGCAGATCGACCTCATTCGCCGTATGTG
TGCCTCTTATTCTGAGCTGGAACTTGTGACCTCAGTTCAAGCTCTGAACAGCACCCAGAAATTG
GCCTGCCTCATTGGTGTGGAGGGTGGCCATTCACTAGACAATAGCCTCGCTGTGCTTCGAAGTT
TCTACCTGCTGGGGGTGCGTTACCTGACACTCACACACACCTGCAACACACCCTGGGCAGAGAG
CTCATCTAAGGACGTCCACTCATTCTACAGCAGTGTCAAAGGACTGACCAGCTTTGGTGAGAAG
GTGGTGGCAGAAATGAATCGCTTAGGGATGATGATTGATTTGTCCCATGTCTCAGACGCTACAG
CCCGGCAGGCTTTGGAAGTATCACAAGCACCTGTGATCTTTTCCCACTCGGCTGCCAGAGCCGT
GTGCCCAAATGCTCGGAATCTCCCTGATGATATCCTGCAGCTCCTGAAGAAGAATGGTGGCATC
GTGATGGTGACCTTTGCTGTAGGAGTGTTACCCTGCAACCCATTAGCCAATGTATCCACTGTGG
CAGATCACTTTGATCACATCAGGACAGTCATTGGATCCGAGTTCATCGGAGTTGGTGGAGATTA
TGACGGTACCAAGCAGTTCCCTCAGGGGCTGGAGGATGTGTCTACATACCCAGTGCTCATAGAG
GAGTTGCTGAGACGAGGCTGGGGTGAACAAGAGCTTCAAGGTGTCCTTCGAGGGAACCTGCTTC
GGGTCTTCAGACAGGTGGAACAGGTACGAGAGAAAAACAAATGGCAGAGTCCCCTGGAAGACAT
GATTCCAGAGGAGCAGCTGGACAGTGCTTGTCACTCAGTCTTACCTCATCGGAGACAGTATCCA
GAAAAGGACCCACCAGAGACTCCAGACTCTCATACACACAAGTTATCACCCAAGATGCCGTACT
CAAAATCCTCTCCCCTCAGAGCCTCAAGCCTTACCATTATGGCCACCTTTTTAGGCCTTCTCAT
ATGACTTTTAGAGGACACCCAGTCCTCTCAGATATCATTCCGGCACCCCAAGAGCCCCTCCACT
TTATTTCCTGCAAGTAAATGCTTTGGGTGTAGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008772487 ⟹ XP_008770709

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,795,322 - 50,806,320 (-)	NCBI
mRatBN7.2	19	33,883,557 - 33,896,487 (-)	NCBI
Rnor_6.0	19	37,964,098 - 37,975,154 (-)	NCBI

Sequence:

show sequence

CGCCCGTGCCTCCCACAGCTCCTTCTTCCCCCGGATACTACCACGTCCTCTACAAAGGGCACGC
ACAAGCCCAGATGGCCTGGCATGGAGAGACATACTGTCTGATTGGAGGCTACCGTGTCTATGGG
GATGCACCGCTTCCCACACCTGTGAAGGTTGAGGAAGAGAAGCCAGCGCCCAGGAGGGCTCCCA
AGAGACAGCGAGTTCAGGAAGAGTCAGATCAAGATCTAGGGTGTCCCAGTGCAAAAATTCCTCG
TCTTAAACTGAAGCATGGTGGCAAAGGGTTTTCGCGACCCTCATCCGTGCCGGTTTGCTCTGCA
CTGAGCAAGATGTCACTCAAGGGCCTCGAGGGTCATTGGGTGCTTAGCCAAGTGTTCCTGTTGG
TGGTGGTGCTGCTGCTGTTAGGGCCCTCAGAACCTCTAATAAGGGCCCAGACAAAACCAGGCAT
CGCTGATGCTTCCACTGCACCAAGCCCCCTCAGAACACTCACCAAGCCTGCCATCTTCAGCATT
CCAACCACTCCTGGCAACCCCAATTTCCCAGACCTGCGAGATCGCACCAGAGCCCTGATGCAGG
ACTTCCCGCTTATAGATGGCCACAATGACCTGCCTCTTGTTCTGAGGCAATTTTACCAGAATGG
ACTACAAGATACTAACCTGAGAAACTTCACCCATGGCCAGACCAGCCTGAATAGGCTTAAAGAT
GGCTTTGTGGGAGCCCAGTTCTGGTCTGCTTACGTGCCGTGCCAGACCCAGGACCGGGATGCCC
TGCGTCTCACACTGGAGCAGATCGACCTCATTCGCCGTATGTGTGCCTCTTATTCTGAGCTGGA
ACTTGTGACCTCAGTTCAAGCTCTGAACAGCACCCAGAAATTGGCCTGCCTCATTGGTGTGGAG
GGTGGCCATTCACTAGACAATAGCCTCGCTGTGCTTCGAAGTTTCTACCTGCTGGGGGTGCGTT
ACCTGACACTCACACACACCTGCAACACACCCTGGGCAGAGAGCTCATCTAAGGACGTCCACTC
ATTCTACAGCAGTGTCAAAGGACTGACCAGCTTTGGTGAGAAGGTGGTGGCAGAAATGAATCGC
TTAGGGATGATGATTGATTTGTCCCATGTCTCAGACGCTACAGCCCGGCAGGCTTTGGAAGTAT
CACAAGCACCTGTGATCTTTTCCCACTCGGCTGCCAGAGCCGTGTGCCCAAATGCTCGGAATCT
CCCTGATGATATCCTGCAGCTCCTGAAGAAGAATGGTGGCATCGTGATGGTGACCTTTGCTGTA
GGAGTGTTACCCTGCAACCCATTAGCCAATGTATCCACTGTGGCAGATCACTTTGATCACATCA
GGACAGTCATTGGATCCGAGTTCATCGGAGTTGGTGGAGATTATGACGGTACCAAGCAGTTCCC
TCAGGGGCTGGAGGATGTGTCTACATACCCAGTGCTCATAGAGGAGTTGCTGAGACGAGGCTGG
GGTGAACAAGAGCTTCAAGGTGTCCTTCGAGGGAACCTGCTTCGGGTCTTCAGACAGGTGGAAC
AGGTACGAGAGAAAAACAAATGGCAGAGTCCCCTGGAAGACATGATTCCAGAGGAGCAGCTGGA
CAGTGCTTGTCACTCAGTCTTACCTCATCGGAGACAGTATCCAGAAAAGGACCCACCAGAGACT
CCAGACTCTCATACACACAAGTTATCACCCAAGATGCCGTACTCAAAATCCTCTCCCCTCAGAG
CCTCAAGCCTTACCATTATGGCCACCTTTTTAGGCCTTCTCATATGACTTTTAGAGGACACCCA
GTCCTCTCAGATATCATTCCGGCACCCCAAGAGCCCCTCCACTTTATTTCCTGCAAGTAAATGC
TTTGGGTGTAGAAACAGA

hide sequence

RefSeq Acc Id:

XM_039097628 ⟹ XP_038953556

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,795,322 - 50,801,853 (-)	NCBI
mRatBN7.2	19	33,885,474 - 33,892,008 (-)	NCBI

RefSeq Acc Id:

XR_005496638

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,795,514 - 50,801,868 (-)	NCBI
mRatBN7.2	19	33,885,482 - 33,892,021 (-)	NCBI

RefSeq Acc Id:

XR_005496639

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	19	50,796,606 - 50,801,868 (-)	NCBI
mRatBN7.2	19	33,886,757 - 33,892,021 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001011928	(Get FASTA)	NCBI Sequence Viewer
	XP_008770709	(Get FASTA)	NCBI Sequence Viewer
	XP_038953556	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88195	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000031955
	ENSRNOP00000031955.5
	ENSRNOP00055024840
	ENSRNOP00060016675
	ENSRNOP00065015526
GenBank Protein	Q5M872	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001011928 ⟸ NM_001011928
- Peptide Label:	precursor
- UniProtKB:	Q5M872 (UniProtKB/Swiss-Prot), A0A8L2QGJ8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSLKGLEGHWVLSQVFLLVVVLLLLGPSEPLIRAQTKPGIADASTAPSPLRTLTKPAIFSIPTT PGNPNFPDLRDRTRALMQDFPLIDGHNDLPLVLRQFYQNGLQDTNLRNFTHGQTSLNRLKDGFV GAQFWSAYVPCQTQDRDALRLTLEQIDLIRRMCASYSELELVTSVQALNSTQKLACLIGVEGGH SLDNSLAVLRSFYLLGVRYLTLTHTCNTPWAESSSKDVHSFYSSVKGLTSFGEKVVAEMNRLGM MIDLSHVSDATARQALEVSQAPVIFSHSAARAVCPNARNLPDDILQLLKKNGGIVMVTFAVGVL PCNPLANVSTVADHFDHIRTVIGSEFIGVGGDYDGTKQFPQGLEDVSTYPVLIEELLRRGWGEQ ELQGVLRGNLLRVFRQVEQVREKNKWQSPLEDMIPEEQLDSACHSVLPHRRQYPEKDPPETPDS HTHKLSPKMPYSKSSPLRASSLTIMATFLGLLI hide sequence

RefSeq Acc Id:	XP_008770709 ⟸ XM_008772487
- Peptide Label:	isoform X2
- UniProtKB:	A0A8L2QGJ8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAWHGETYCLIGGYRVYGDAPLPTPVKVEEEKPAPRRAPKRQRVQEESDQDLGCPSAKIPRLKL KHGGKGFSRPSSVPVCSALSKMSLKGLEGHWVLSQVFLLVVVLLLLGPSEPLIRAQTKPGIADA STAPSPLRTLTKPAIFSIPTTPGNPNFPDLRDRTRALMQDFPLIDGHNDLPLVLRQFYQNGLQD TNLRNFTHGQTSLNRLKDGFVGAQFWSAYVPCQTQDRDALRLTLEQIDLIRRMCASYSELELVT SVQALNSTQKLACLIGVEGGHSLDNSLAVLRSFYLLGVRYLTLTHTCNTPWAESSSKDVHSFYS SVKGLTSFGEKVVAEMNRLGMMIDLSHVSDATARQALEVSQAPVIFSHSAARAVCPNARNLPDD ILQLLKKNGGIVMVTFAVGVLPCNPLANVSTVADHFDHIRTVIGSEFIGVGGDYDGTKQFPQGL EDVSTYPVLIEELLRRGWGEQELQGVLRGNLLRVFRQVEQVREKNKWQSPLEDMIPEEQLDSAC HSVLPHRRQYPEKDPPETPDSHTHKLSPKMPYSKSSPLRASSLTIMATFLGLLI hide sequence

RefSeq Acc Id:

ENSRNOP00000031955 ⟸ ENSRNOT00000034722

RefSeq Acc Id:	XP_038953556 ⟸ XM_039097628
- Peptide Label:	isoform X1

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5M872-F1-model_v2	AlphaFold	Q5M872	1-481	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701098

Promoter ID:

EPDNEW_R11622

Type:

multiple initiation site

Name:

Dpep2_1

Description:

dipeptidase 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	37,970,567 - 37,970,627	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305746	AgrOrtholog
BioCyc Gene	G2FUF-5794	BioCyc
Ensembl Genes	ENSRNOG00000023303	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00055018202	UniProtKB/Swiss-Prot
	ENSRNOG00060012459	UniProtKB/Swiss-Prot
	ENSRNOG00065012422	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000034722	ENTREZGENE
	ENSRNOT00000034722.6	UniProtKB/TrEMBL
	ENSRNOT00055030852	UniProtKB/Swiss-Prot
	ENSRNOT00060021133	UniProtKB/Swiss-Prot
	ENSRNOT00065020225	UniProtKB/Swiss-Prot
Gene3D-CATH	Metal-dependent hydrolases	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7374282	IMAGE-MGC_LOAD
InterPro	Dipep_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Metal_Hydrolase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pept_M19	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:291984	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:108872	IMAGE-MGC_LOAD
NCBI Gene	291984	ENTREZGENE
PANTHER	DIPEPTIDASE 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10443	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Peptidase_M19	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Dpep2	PhenoGen
PROSITE	RENAL_DIPEPTIDASE_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RENAL_DIPEPTIDASE_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000023303	RatGTEx
	ENSRNOG00055018202	RatGTEx
	ENSRNOG00060012459	RatGTEx
	ENSRNOG00065012422	RatGTEx
Superfamily-SCOP	SSF51556	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8L2QGJ8	ENTREZGENE, UniProtKB/TrEMBL
	DPEP2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Dpep2	dipeptidase 2	Dpep2_predicted	dipeptidase 2 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Dpep2_predicted	dipeptidase 2 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar