Mdm2 | Rat | (+)-catechin | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Catechin results in decreased expression of MDM2 mRNA | CTD | PMID:23706674 |
Mdm2 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of MDM2 mRNA] | CTD | PMID:31150632 |
Mdm2 | Rat | (-)-demecolcine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of MDM2 mRNA | CTD | PMID:23649840 |
Mdm2 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9 more ... | CTD | PMID:23717041 |
Mdm2 | Rat | (S)-naringenin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [naringenin co-treated with bisphenol A] results in increased expression of MDM2 mRNA and [naringenin metabolite co-treated with bisphenol A] results in increased expression of MDM2 mRNA | CTD | PMID:36235125 |
Mdm2 | Rat | (S)-naringenin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | naringenin metabolite results in increased expression of MDM2 mRNA | CTD | PMID:36235125 |
Mdm2 | Rat | (S)-nicotine | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [[Nicotine results in decreased expression of RPS27A protein] which results in increased phosphorylation of MDM2 protein] which results in increased ubiquitination of TP53 protein and [Nicotine results in decreased expression of RPS27A protein] which results in increased phosphorylation of MDM2 protein | CTD | PMID:30272249 |
Mdm2 | Rat | 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | o and p'-DDT affects the expression of MDM2 mRNA | CTD | PMID:18925944 |
Mdm2 | Rat | 1,10-phenanthroline | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 1 and 10-phenanthroline results in increased expression of MDM2 mRNA | CTD | PMID:19502547 |
Mdm2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of MDM2 mRNA | CTD | PMID:22206623 |
Mdm2 | Rat | 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile | increases expression | EXP | | 6480464 | Citalopram results in increased expression of MDM2 mRNA | CTD | PMID:28467792 |
Mdm2 | Rat | 1-nitropyrene | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 1-nitropyrene results in increased expression of MDM2 mRNA more ... | CTD | PMID:10837373 and PMID:22044530 |
Mdm2 | Rat | 1-nitropyrene | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | nutlin 3 results in increased susceptibility to [1-nitropyrene results in increased expression of MDM2 protein modified form] more ... | CTD | PMID:10837373 and PMID:22044530 |
Mdm2 | Rat | 10-Hydroxycamptothecin | affects response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 protein affects the susceptibility to 10-hydroxycamptothecin | CTD | PMID:13130078 |
Mdm2 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Ethinyl Estradiol results in increased expression of MDM2 mRNA alternative form and Ethinyl Estradiol results in increased expression of MDM2 protein | CTD | PMID:12168835 |
Mdm2 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of MDM2 mRNA | CTD | PMID:17942748 |
Mdm2 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MDM2 mRNA | CTD | PMID:17942748 |
Mdm2 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of MDM2 mRNA | CTD | PMID:17555576 |
Mdm2 | Rat | 17beta-estradiol | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of MDM2 mRNA alternative form and Estradiol results in increased expression of MDM2 protein | CTD | PMID:12168835 |
Mdm2 | Rat | 17beta-estradiol | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Estradiol results in increased expression of MDM2 mRNA and Estradiol results in increased expression of MDM2 protein | CTD | PMID:23684557 |
Mdm2 | Rat | 17beta-estradiol | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Parathion] results in increased expression of MDM2 mRNA and [Estradiol co-treated with TGFB1 protein] results in decreased expression of MDM2 mRNA | CTD | PMID:17622325 and PMID:30165855 |
Mdm2 | Rat | 17beta-estradiol | decreases phosphorylation | ISO | Mdm2 (Mus musculus) | 6480464 | Estradiol results in decreased phosphorylation of MDM2 protein | CTD | PMID:22314386 |
Mdm2 | Rat | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 1H-(1 more ... | CTD | PMID:16288207 |
Mdm2 | Rat | 2,2',3,3',6,6'-hexachlorobiphenyl | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19751709 |
Mdm2 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:20840854 |
Mdm2 | Rat | 2,2',4,4',5,5'-hexachlorobiphenyl | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19751709 and PMID:20840854 |
Mdm2 | Rat | 2,2',4,4'-tetrachlorobiphenyl | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19751709 |
Mdm2 | Rat | 2,2',4,5-tetrachlorobiphenyl | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19751709 |
Mdm2 | Rat | 2,2',5,5'-tetrachlorobiphenyl | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19751709 |
Mdm2 | Rat | 2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:21647879 |
Mdm2 | Rat | 2,3,3',4,4',5,5'-Heptachlorobiphenyl | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19751709 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]] more ... | CTD | PMID:19578757 and PMID:22044530 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA | CTD | PMID:33387578 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA | CTD | PMID:12167310 more ... |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MDM2 mRNA | CTD | PMID:21570461 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases phosphorylation | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased phosphorylation of MDM2 protein | CTD | PMID:15459018 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein] and Tetrachlorodibenzodioxin results in increased expression of and results in increased phosphorylation of and results in increased activity of MDM2 protein | CTD | PMID:15459018 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases degradation | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased degradation of MDM2 protein | CTD | PMID:15459018 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MDM2 mRNA | CTD | PMID:17942748 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA | CTD | PMID:19578757 |
Mdm2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MDM2 mRNA | CTD | PMID:16039398 |
Mdm2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of MDM2 mRNA | CTD | PMID:21346803 |
Mdm2 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of MDM2 mRNA | CTD | PMID:21346803 |
Mdm2 | Rat | 2-acetamidofluorene | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 protein | CTD | PMID:11003613 |
Mdm2 | Rat | 2-acetamidofluorene | increases expression | EXP | | 6480464 | 2-Acetylaminofluorene results in increased expression of MDM2 mRNA and 2-Acetylaminofluorene results in increased expression of MDM2 protein | CTD | PMID:19167416 more ... |
Mdm2 | Rat | 2-acetamidofluorene | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | 2-Acetylaminofluorene results in increased expression of MDM2 mRNA | CTD | PMID:21607683 |
Mdm2 | Rat | 2-nitrofluorene | increases expression | EXP | | 6480464 | 2-nitrofluorene results in increased expression of MDM2 mRNA | CTD | PMID:14600272 more ... |
Mdm2 | Rat | 3,3',4,4',5-pentachlorobiphenyl | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | 3 more ... | CTD | PMID:19751709 and PMID:20840854 |
Mdm2 | Rat | 3,3',4,4',5-pentachlorobiphenyl | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | 3 more ... | CTD | PMID:20840854 |
Mdm2 | Rat | 3,3'-diindolylmethane | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | 3 and 3'-diindolylmethane analog results in decreased expression of MDM2 mRNA | CTD | PMID:26593444 |
Mdm2 | Rat | 3,4,8-Trimethyl-1H,2H,3H-imidazo[4,5-F]quinoxalin-2-imine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 3 more ... | CTD | PMID:23810796 |
Mdm2 | Rat | 3-phenylprop-2-enal | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | cinnamaldehyde results in increased expression of MDM2 mRNA | CTD | PMID:19000754 |
Mdm2 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of MDM2 mRNA | CTD | PMID:18648102 |
Mdm2 | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | Mdm2 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of MDM2 promoter | CTD | PMID:33297965 |
Mdm2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of MDM2 mRNA | CTD | PMID:39298647 |
Mdm2 | Rat | 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one | increases expression | EXP | | 6480464 | 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of MDM2 mRNA | CTD | PMID:14600272 more ... |
Mdm2 | Rat | 4-hydroperoxycyclophosphamide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | perfosfamide results in increased expression of MDM2 | CTD | PMID:18034189 |
Mdm2 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Fenretinide results in decreased expression of MDM2 mRNA | CTD | PMID:16570282 |
Mdm2 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of MDM2 mRNA | CTD | PMID:28973697 |
Mdm2 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Decitabine affects the expression of MDM2 mRNA | CTD | PMID:17145863 |
Mdm2 | Rat | 5-azacytidine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Azacitidine results in increased expression of MDM2 mRNA | CTD | PMID:20823114 |
Mdm2 | Rat | 5-fluorouracil | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Fluorouracil results in increased expression of MDM2 mRNA | CTD | PMID:16949053 |
Mdm2 | Rat | 5-fluorouracil | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Fluorouracil results in increased phosphorylation of MDM2 protein | CTD | PMID:25744307 |
Mdm2 | Rat | 5-fluorouracil | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Fluorouracil results in increased expression of MDM2 mRNA more ... | CTD | PMID:14665630 more ... |
Mdm2 | Rat | 5-fluorouracil | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Cadmium Chloride affects the reaction [Fluorouracil results in increased phosphorylation of MDM2 protein] more ... | CTD | PMID:15546879 more ... |
Mdm2 | Rat | 7,12-dimethyltetraphene | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [epigallocatechin gallate co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9 more ... | CTD | PMID:23717041 |
Mdm2 | Rat | 7,12-dimethyltetraphene | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | 9 more ... | CTD | PMID:23717041 and PMID:32553695 |
Mdm2 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of MDM2 mRNA | CTD | PMID:31881176 |
Mdm2 | Rat | acetylsalicylic acid | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Aspirin results in decreased expression of MDM2 mRNA | CTD | PMID:20457246 |
Mdm2 | Rat | actinomycin D | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Dactinomycin results in increased expression of MDM2 mRNA | CTD | PMID:38460933 |
Mdm2 | Rat | actinomycin D | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of MDM2 mRNA and [Dactinomycin co-treated with nutlin 3] results in increased secretion of MDM2 protein | CTD | PMID:38460933 |
Mdm2 | Rat | adefovir pivoxil | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | adefovir dipivoxil results in increased expression of MDM2 mRNA | CTD | PMID:25596134 |
Mdm2 | Rat | aflatoxin B1 | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of MDM2 protein | CTD | PMID:20106945 |
Mdm2 | Rat | aflatoxin B1 | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:21632981 more ... |
Mdm2 | Rat | aflatoxin B1 | decreases methylation | ISO | MDM2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of MDM2 gene | CTD | PMID:27153756 |
Mdm2 | Rat | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:14600272 more ... |
Mdm2 | Rat | aflatoxin B1 | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of MDM2 mRNA | CTD | PMID:19770486 |
Mdm2 | Rat | aflatoxin M1 | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of MDM2 mRNA | CTD | PMID:30928695 |
Mdm2 | Rat | alpha-naphthoflavone | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [Oxygen deficiency results in increased expression of MDM2 mRNA]] and alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of MDM2 mRNA] | CTD | PMID:19578757 |
Mdm2 | Rat | alvocidib | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | alvocidib results in decreased expression of MDM2 mRNA and alvocidib results in decreased expression of MDM2 protein | CTD | PMID:12589031 |
Mdm2 | Rat | amifostine | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Amifostine results in decreased expression of MDM2 mRNA | CTD | PMID:14555708 |
Mdm2 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of MDM2 mRNA | CTD | PMID:38685447 |
Mdm2 | Rat | ammonium chloride | increases expression | EXP | | 6480464 | Ammonium Chloride results in increased expression of MDM2 mRNA and Ammonium Chloride results in increased expression of MDM2 protein | CTD | PMID:12420312 and PMID:16483693 |
Mdm2 | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of MDM2 mRNA | CTD | PMID:30779732 |
Mdm2 | Rat | amphibole asbestos | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Asbestos and Amphibole results in decreased expression of MDM2 protein | CTD | PMID:20855422 |
Mdm2 | Rat | amsacrine | decreases response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 promoter SNP results in decreased susceptibility to Amsacrine | CTD | PMID:17575151 |
Mdm2 | Rat | androstane | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | Androstanols inhibits the reaction [DDT results in increased expression of MDM2 mRNA] | CTD | PMID:23684557 |
Mdm2 | Rat | antimycin A | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Antimycin A results in increased expression of MDM2 mRNA | CTD | PMID:33512557 |
Mdm2 | Rat | arsane | affects response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 SNP affects the susceptibility to Arsenic | CTD | PMID:21982800 |
Mdm2 | Rat | arsane | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Arsenic results in increased expression of MDM2 protein | CTD | PMID:35821281 |
Mdm2 | Rat | arsane | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of MDM2 mRNA and USP7 protein affects the reaction [Arsenic results in increased expression of MDM2 protein] | CTD | PMID:35821281 and PMID:39836092 |
Mdm2 | Rat | arsane | affects methylation | ISO | MDM2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of MDM2 gene | CTD | PMID:25304211 |
Mdm2 | Rat | arsenic atom | affects response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 SNP affects the susceptibility to Arsenic | CTD | PMID:21982800 |
Mdm2 | Rat | arsenic atom | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Arsenic results in increased expression of MDM2 protein | CTD | PMID:35821281 |
Mdm2 | Rat | arsenic atom | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of MDM2 mRNA and USP7 protein affects the reaction [Arsenic results in increased expression of MDM2 protein] | CTD | PMID:35821281 and PMID:39836092 |
Mdm2 | Rat | arsenic atom | affects methylation | ISO | MDM2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of MDM2 gene | CTD | PMID:25304211 |
Mdm2 | Rat | arsenite(3-) | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [[[arsenite results in increased activity of PRKDC protein] which results in increased phosphorylation of and results in increased activity of MAPK9 protein] promotes the reaction [MAPK9 protein binds to TP53 protein]] inhibits the reaction [MDM2 results in increased degradation of and results in decreased stability of TP53 protein] more ... | CTD | PMID:22366412 more ... |
Mdm2 | Rat | arsenite(3-) | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | arsenite results in increased expression of MDM2 mRNA more ... | CTD | PMID:30177839 and PMID:34425169 |
Mdm2 | Rat | arsenous acid | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of MDM2 mRNA | CTD | PMID:20458559 |
Mdm2 | Rat | arsenous acid | multiple interactions | EXP | | 6480464 | pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of MDM2 mRNA] | CTD | PMID:17487067 |
Mdm2 | Rat | arsenous acid | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of MDM2 mRNA | CTD | PMID:17487067 |
Mdm2 | Rat | arsenous acid | decreases expression | EXP | | 6480464 | Arsenic Trioxide results in decreased expression of MDM2 mRNA | CTD | PMID:21145380 |
Mdm2 | Rat | arsenous acid | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of MDM2 mRNA | CTD | PMID:20862710 more ... |
Mdm2 | Rat | aspartame | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Fats and Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MDM2 mRNA | CTD | PMID:23783067 |
Mdm2 | Rat | atorvastatin calcium | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Atorvastatin results in increased expression of MDM2 protein | CTD | PMID:29630879 |
Mdm2 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of MDM2 gene | CTD | PMID:28931070 and PMID:35440735 |
Mdm2 | Rat | avobenzone | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | avobenzone results in increased expression of MDM2 mRNA | CTD | PMID:31016361 |
Mdm2 | Rat | azoxystrobin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | azoxystrobin results in increased expression of MDM2 protein | CTD | PMID:32339800 |
Mdm2 | Rat | benzene | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | TRP53 protein affects the reaction [Benzene results in increased expression of MDM2 mRNA] | CTD | PMID:11896287 |
Mdm2 | Rat | benzene | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Benzene results in increased expression of MDM2 mRNA | CTD | PMID:11896287 more ... |
Mdm2 | Rat | benzene | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 gene polymorphism affects the reaction [CDKN2A gene polymorphism affects the susceptibility to Benzene] | CTD | PMID:19596022 |
Mdm2 | Rat | benzene | multiple interactions | EXP | | 6480464 | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA | CTD | PMID:17905399 |
Mdm2 | Rat | benzo[a]pyrene | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of MDM2 mRNA more ... | CTD | PMID:10837373 more ... |
Mdm2 | Rat | benzo[a]pyrene | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of MDM2 mRNA | CTD | PMID:30562542 |
Mdm2 | Rat | benzo[a]pyrene | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of MDM2 mRNA | CTD | PMID:27858113 |
Mdm2 | Rat | benzo[a]pyrene | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased phosphorylation of MDM2 protein | CTD | PMID:20840854 and PMID:25744307 |
Mdm2 | Rat | benzo[a]pyrene | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Benzo(a)pyrene metabolite results in increased expression of MDM2 mRNA and Benzo(a)pyrene results in increased expression of MDM2 mRNA | CTD | PMID:18656336 more ... |
Mdm2 | Rat | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of MDM2 protein | CTD | PMID:21467743 |
Mdm2 | Rat | benzo[a]pyrene | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:10837373 more ... |
Mdm2 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 more ... |
Mdm2 | Rat | benzo[b]fluoranthene | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of MDM2 mRNA | CTD | PMID:26377693 |
Mdm2 | Rat | benzo[b]fluoranthene | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of MDM2 mRNA | CTD | PMID:27858113 |
Mdm2 | Rat | beta-naphthoflavone | increases phosphorylation | EXP | | 6480464 | beta-Naphthoflavone results in increased phosphorylation of MDM2 protein | CTD | PMID:26558467 |
Mdm2 | Rat | biphenyl-4-amine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 4-biphenylamine results in increased expression of MDM2 mRNA | CTD | PMID:32905825 |
Mdm2 | Rat | biphenyl-4-amine | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | TP53 protein inhibits the reaction [4-biphenylamine results in increased expression of MDM2 mRNA] | CTD | PMID:32905825 |
Mdm2 | Rat | bis(2-chloroethyl) sulfide | affects expression | EXP | | 6480464 | Mustard Gas affects the expression of MDM2 mRNA | CTD | PMID:15651846 |
Mdm2 | Rat | bis(2-chloroethyl) sulfide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Mustard Gas results in increased expression of MDM2 mRNA | CTD | PMID:33491125 |
Mdm2 | Rat | bis(2-chloroethyl) sulfide | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Mustard Gas results in increased expression of MDM2 mRNA | CTD | PMID:15674843 and PMID:18955075 |
Mdm2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of MDM2 mRNA | CTD | PMID:31163220 |
Mdm2 | Rat | bis(2-ethylhexyl) phthalate | decreases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased phosphorylation of MDM2 protein | CTD | PMID:31163220 |
Mdm2 | Rat | bisphenol A | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of MDM2 mRNA | CTD | PMID:26063408 |
Mdm2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of MDM2 mRNA | CTD | PMID:30816183 more ... |
Mdm2 | Rat | bisphenol A | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | bisphenol A analog results in increased expression of MDM2 mRNA and bisphenol A results in increased expression of MDM2 mRNA | CTD | PMID:29275510 and PMID:32387340 |
Mdm2 | Rat | bisphenol A | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of MDM2 mRNA | CTD | PMID:30903817 |
Mdm2 | Rat | bisphenol A | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [naringenin co-treated with bisphenol A] results in increased expression of MDM2 mRNA more ... | CTD | PMID:24831732 and PMID:36235125 |
Mdm2 | Rat | bisphenol A | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | bisphenol A results in increased phosphorylation of MDM2 protein | CTD | PMID:24831732 |
Mdm2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of MDM2 mRNA | CTD | PMID:25181051 |
Mdm2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MDM2 mRNA | CTD | PMID:26982218 |
Mdm2 | Rat | bisphenol AF | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [bisphenol AF co-treated with cylindrospermopsin] results in increased expression of MDM2 mRNA | CTD | PMID:32244372 |
Mdm2 | Rat | bisphenol F | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | bisphenol F results in increased expression of MDM2 mRNA | CTD | PMID:35387338 |
Mdm2 | Rat | bortezomib | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [CASP8 protein results in increased activity of CASP3 protein] affects the reaction [Bortezomib results in increased cleavage of MDM2 protein] and Bortezomib promotes the reaction [TP53 protein binds to MDM2 protein] | CTD | PMID:12393500 |
Mdm2 | Rat | bortezomib | increases cleavage | ISO | MDM2 (Homo sapiens) | 6480464 | Bortezomib results in increased cleavage of MDM2 protein | CTD | PMID:12393500 |
Mdm2 | Rat | bortezomib | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Bortezomib affects the expression of MDM2 protein | CTD | PMID:12393500 |
Mdm2 | Rat | brassinolide | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | brassinolide results in decreased expression of MDM2 protein | CTD | PMID:20833159 |
Mdm2 | Rat | cadmium acetate | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | cadmium acetate results in increased expression of MDM2 protein | CTD | PMID:15450950 |
Mdm2 | Rat | cadmium atom | decreases expression | EXP | | 6480464 | Cadmium results in decreased expression of MDM2 mRNA | CTD | PMID:21467746 |
Mdm2 | Rat | cadmium atom | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Cadmium results in increased expression of MDM2 mRNA | CTD | PMID:22666406 |
Mdm2 | Rat | cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of MDM2 mRNA | CTD | PMID:22110744 |
Mdm2 | Rat | cadmium dichloride | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of MDM2 mRNA | CTD | PMID:38568856 |
Mdm2 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of MDM2 mRNA | CTD | PMID:31077537 |
Mdm2 | Rat | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of MDM2 mRNA | CTD | PMID:31077537 |
Mdm2 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of MDM2 mRNA | CTD | PMID:23405080 |
Mdm2 | Rat | cadmium dichloride | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MDM2 protein] more ... | CTD | PMID:25744307 |
Mdm2 | Rat | cadmium dichloride | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased phosphorylation of MDM2 protein | CTD | PMID:25744307 |
Mdm2 | Rat | cadmium dichloride | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Cadmium Chloride results in increased expression of MDM2 mRNA | CTD | PMID:11958953 more ... |
Mdm2 | Rat | cadmium dichloride | increases phosphorylation | ISO | Mdm2 (Mus musculus) | 6480464 | Cadmium Chloride results in increased phosphorylation of MDM2 protein | CTD | PMID:20525538 and PMID:22314386 |
Mdm2 | Rat | cadmium dichloride | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein] more ... | CTD | PMID:11958953 and PMID:12135628 |
Mdm2 | Rat | caffeine | decreases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of MDM2 protein | CTD | PMID:35688186 |
Mdm2 | Rat | camptothecin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Camptothecin results in increased expression of MDM2 protein | CTD | PMID:17555331 |
Mdm2 | Rat | cannabidiol | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [lipopolysaccharide and E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MDM2 mRNA | CTD | PMID:30742662 |
Mdm2 | Rat | cannabidiol | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Cannabidiol results in increased expression of MDM2 mRNA | CTD | PMID:27932991 and PMID:30713602 |
Mdm2 | Rat | cannabidiol | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Cannabidiol results in increased expression of MDM2 mRNA | CTD | PMID:30742662 |
Mdm2 | Rat | cantharidin | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Cantharidin results in decreased expression of MDM2 mRNA | CTD | PMID:31945315 |
Mdm2 | Rat | capsaicin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Capsaicin promotes the reaction [resveratrol results in decreased expression of MDM2 protein] more ... | CTD | PMID:19846903 |
Mdm2 | Rat | capsaicin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Capsaicin results in increased expression of MDM2 mRNA | CTD | PMID:19502594 |
Mdm2 | Rat | capsaicin | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Capsaicin results in decreased expression of MDM2 protein | CTD | PMID:19846903 |
Mdm2 | Rat | Carbadox | increases expression | EXP | | 6480464 | Carbadox results in increased expression of MDM2 mRNA | CTD | PMID:26558467 |
Mdm2 | Rat | carbamazepine | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of MDM2 mRNA | CTD | PMID:25979313 |
Mdm2 | Rat | carbonyl cyanide p-trifluoromethoxyphenylhydrazone | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of MDM2 mRNA | CTD | PMID:16039398 |
Mdm2 | Rat | chlorambucil | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Chlorambucil results in increased expression of MDM2 mRNA | CTD | PMID:17476690 |
Mdm2 | Rat | chloroacetaldehyde | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | chloroacetaldehyde results in increased expression of MDM2 mRNA | CTD | PMID:25596134 |
Mdm2 | Rat | chloroethene | affects response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 polymorphism affects the susceptibility to Vinyl Chloride | CTD | PMID:24464562 |
Mdm2 | Rat | chloroprene | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Chloroprene results in increased expression of MDM2 mRNA | CTD | PMID:23125180 |
Mdm2 | Rat | chlorpromazine | increases expression | EXP | | 6480464 | Chlorpromazine results in increased expression of MDM2 mRNA | CTD | PMID:25596134 |
Mdm2 | Rat | chlorpyrifos | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Chlorpyrifos results in increased expression of MDM2 mRNA | CTD | PMID:30981936 |
Mdm2 | Rat | chlorpyrifos | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of MDM2 mRNA | CTD | PMID:37019170 |
Mdm2 | Rat | choline | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MDM2 gene | CTD | PMID:20938992 |
Mdm2 | Rat | chrysene | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of MDM2 mRNA | CTD | PMID:27858113 |
Mdm2 | Rat | cidofovir anhydrous | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Cidofovir affects the expression of MDM2 mRNA | CTD | PMID:25596134 |
Mdm2 | Rat | cisplatin | increases expression | EXP | | 6480464 | Cisplatin results in increased expression of MDM2 mRNA | CTD | PMID:24880025 |
Mdm2 | Rat | cisplatin | decreases expression | EXP | | 6480464 | Cisplatin results in decreased expression of MDM2 mRNA and Cisplatin results in decreased expression of MDM2 protein | CTD | PMID:35842499 |
Mdm2 | Rat | cisplatin | multiple interactions | EXP | | 6480464 | Cisplatin promotes the reaction [NFE2L2 protein results in increased expression of MDM2 mRNA] more ... | CTD | PMID:35842499 |
Mdm2 | Rat | cisplatin | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Cisplatin results in increased expression of MDM2 mRNA and Cisplatin results in increased expression of MDM2 protein | CTD | PMID:21151649 more ... |
Mdm2 | Rat | cisplatin | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | Cisplatin promotes the reaction [TRP53 protein results in increased expression of MDM2] more ... | CTD | PMID:21552291 more ... |
Mdm2 | Rat | cisplatin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of MDM2 mRNA and Cisplatin results in increased expression of MDM2 protein | CTD | PMID:16797627 more ... |
Mdm2 | Rat | cisplatin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with eprenetapopt co-treated with Oxygen deficiency] results in increased expression of MDM2 mRNA more ... | CTD | PMID:21509038 more ... |
Mdm2 | Rat | citalopram | increases expression | EXP | | 6480464 | Citalopram results in increased expression of MDM2 mRNA | CTD | PMID:28467792 |
Mdm2 | Rat | clofibrate | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of MDM2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of MDM2 mRNA] | CTD | PMID:17585979 |
Mdm2 | Rat | cobalt atom | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Cobalt results in increased expression of MDM2 mRNA | CTD | PMID:24068677 |
Mdm2 | Rat | cobalt atom | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | TP53 protein affects the reaction [Cobalt results in increased expression of MDM2 mRNA] | CTD | PMID:24068677 |
Mdm2 | Rat | cobalt dichloride | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of MDM2 protein | CTD | PMID:19714248 |
Mdm2 | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of MDM2 mRNA | CTD | PMID:24386269 |
Mdm2 | Rat | cobalt dichloride | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 protein promotes the reaction [cobaltous chloride inhibits the reaction [HIPK2 protein promotes the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of TP53 protein]]] | CTD | PMID:19714248 |
Mdm2 | Rat | copper atom | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Copper results in increased expression of MDM2 mRNA | CTD | PMID:16629173 |
Mdm2 | Rat | copper atom | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Chelating Agents binds to Copper] which results in increased expression of MDM2 mRNA | CTD | PMID:30911355 |
Mdm2 | Rat | copper(0) | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Copper results in increased expression of MDM2 mRNA | CTD | PMID:16629173 |
Mdm2 | Rat | copper(0) | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Chelating Agents binds to Copper] which results in increased expression of MDM2 mRNA | CTD | PMID:30911355 |
Mdm2 | Rat | corn oil | decreases expression | EXP | | 6480464 | Corn Oil results in decreased expression of MDM2 mRNA | CTD | PMID:22760963 |
Mdm2 | Rat | coumarin | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | coumarin analog results in decreased expression of MDM2 mRNA | CTD | PMID:32578917 |
Mdm2 | Rat | crocidolite asbestos | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of MDM2 mRNA | CTD | PMID:29279043 |
Mdm2 | Rat | cryptolepine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | cryptolepine results in increased expression of MDM2 mRNA and cryptolepine results in increased expression of MDM2 protein | CTD | PMID:16120219 |
Mdm2 | Rat | curcumin | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | [Curcumin results in decreased expression of MDM2 protein] which results in decreased expression of CDKN1A mRNA more ... | CTD | PMID:17332326 |
Mdm2 | Rat | curcumin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Curcumin analog results in increased expression of MDM2 mRNA | CTD | PMID:26409325 |
Mdm2 | Rat | curcumin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Curcumin inhibits the reaction [bisphenol A results in increased phosphorylation of MDM2 protein] | CTD | PMID:24831732 |
Mdm2 | Rat | cyclosporin A | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of MDM2 mRNA | CTD | PMID:20106945 more ... |
Mdm2 | Rat | cylindrospermopsin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of MDM2 mRNA | CTD | PMID:21607682 |
Mdm2 | Rat | cylindrospermopsin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [bisphenol AF co-treated with cylindrospermopsin] results in increased expression of MDM2 mRNA | CTD | PMID:32244372 |
Mdm2 | Rat | cyproconazole | multiple interactions | EXP | | 6480464 | [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of MDM2 mRNA and [cyproconazole co-treated with epoxiconazole] results in increased expression of MDM2 mRNA | CTD | PMID:29038839 |
Mdm2 | Rat | DAPT | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | N-(N-(3 and 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in increased expression of MDM2 protein | CTD | PMID:25005833 |
Mdm2 | Rat | DAPT | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Hydrogen Peroxide inhibits the reaction [N-(N-(3 and 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester results in increased expression of MDM2 protein] | CTD | PMID:25005833 |
Mdm2 | Rat | DDT | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | Androstanols inhibits the reaction [DDT results in increased expression of MDM2 mRNA] | CTD | PMID:23684557 |
Mdm2 | Rat | DDT | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | DDT results in increased expression of MDM2 mRNA and DDT results in increased expression of MDM2 protein | CTD | PMID:23684557 |
Mdm2 | Rat | deguelin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | deguelin results in increased expression of MDM2 mRNA | CTD | PMID:33512557 |
Mdm2 | Rat | DENSPM | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Fluorouracil promotes the reaction [N(1) more ... | CTD | PMID:15546879 |
Mdm2 | Rat | DENSPM | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | N(1) and N(11)-diethylnorspermine results in increased expression of MDM2 protein | CTD | PMID:15546879 |
Mdm2 | Rat | deoxynivalenol | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | deoxynivalenol results in increased expression of MDM2 mRNA | CTD | PMID:31863870 |
Mdm2 | Rat | desferrioxamine B | increases expression | EXP | | 6480464 | Deferoxamine results in increased expression of MDM2 protein | CTD | PMID:19950214 |
Mdm2 | Rat | diallyl disulfide | multiple interactions | EXP | | 6480464 | [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of MDM2 mRNA | CTD | PMID:31077537 |
Mdm2 | Rat | diallyl trisulfide | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | diallyl trisulfide results in decreased expression of MDM2 protein | CTD | PMID:24415872 |
Mdm2 | Rat | diallyl trisulfide | increases degradation | ISO | MDM2 (Homo sapiens) | 6480464 | diallyl trisulfide results in increased degradation of MDM2 protein | CTD | PMID:23754639 |
Mdm2 | Rat | diarsenic trioxide | multiple interactions | EXP | | 6480464 | pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of MDM2 mRNA] | CTD | PMID:17487067 |
Mdm2 | Rat | diarsenic trioxide | decreases expression | EXP | | 6480464 | Arsenic Trioxide results in decreased expression of MDM2 mRNA | CTD | PMID:21145380 |
Mdm2 | Rat | diarsenic trioxide | increases expression | EXP | | 6480464 | Arsenic Trioxide results in increased expression of MDM2 mRNA | CTD | PMID:17487067 |
Mdm2 | Rat | diarsenic trioxide | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of MDM2 mRNA | CTD | PMID:20458559 |
Mdm2 | Rat | diarsenic trioxide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of MDM2 mRNA | CTD | PMID:20862710 more ... |
Mdm2 | Rat | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of MDM2 mRNA | CTD | PMID:22546817 |
Mdm2 | Rat | dibenz[a,h]anthracene | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | 1 more ... | CTD | PMID:26377693 |
Mdm2 | Rat | diclofenac | decreases expression | EXP | | 6480464 | Diclofenac results in decreased expression of MDM2 mRNA | CTD | PMID:17202759 |
Mdm2 | Rat | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of MDM2 mRNA | CTD | PMID:22546817 |
Mdm2 | Rat | dieldrin | affects methylation | ISO | Mdm2 (Mus musculus) | 6480464 | Dieldrin affects the methylation of MDM2 gene | CTD | PMID:38995845 |
Mdm2 | Rat | diepoxybutane | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | diepoxybutane inhibits the reaction [TP53 protein binds to MDM2 protein] | CTD | PMID:20024960 |
Mdm2 | Rat | diethylstilbestrol | affects mutagenesis | ISO | Mdm2 (Mus musculus) | 6480464 | Diethylstilbestrol affects the mutagenesis of MDM2 gene | CTD | PMID:7916985 |
Mdm2 | Rat | diethylstilbestrol | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Diethylstilbestrol results in decreased expression of MDM2 mRNA | CTD | PMID:21041162 |
Mdm2 | Rat | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of MDM2 mRNA | CTD | PMID:15890375 |
Mdm2 | Rat | diethylstilbestrol | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Diethylstilbestrol results in increased expression of MDM2 mRNA | CTD | PMID:15545218 |
Mdm2 | Rat | dimethylarsinic acid | increases expression | EXP | | 6480464 | Cacodylic Acid results in increased expression of MDM2 mRNA | CTD | PMID:17481689 |
Mdm2 | Rat | dimethylarsinic acid | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MDM2 mRNA | CTD | PMID:23192986 |
Mdm2 | Rat | dioxygen | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Cisplatin co-treated with eprenetapopt co-treated with Oxygen deficiency] results in increased expression of MDM2 mRNA more ... | CTD | PMID:19578757 and PMID:29690507 |
Mdm2 | Rat | dioxygen | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of MDM2 mRNA | CTD | PMID:30529165 |
Mdm2 | Rat | dioxygen | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of MDM2 mRNA and Oxygen deficiency results in increased expression of MDM2 protein | CTD | PMID:19502547 more ... |
Mdm2 | Rat | disodium selenite | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of MDM2 mRNA | CTD | PMID:24383545 |
Mdm2 | Rat | dorsomorphin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 |
Mdm2 | Rat | doxorubicin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Doxorubicin inhibits the reaction [TP53 protein binds to MDM2 protein] more ... | CTD | PMID:17935137 more ... |
Mdm2 | Rat | doxorubicin | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | Doxorubicin affects the expression of MDM2 mRNA | CTD | PMID:29653124 |
Mdm2 | Rat | doxorubicin | increases expression | EXP | | 6480464 | Doxorubicin results in increased expression of MDM2 mRNA | CTD | PMID:12187937 more ... |
Mdm2 | Rat | doxorubicin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of MDM2 mRNA and Doxorubicin results in increased expression of MDM2 protein | CTD | PMID:14665630 more ... |
Mdm2 | Rat | doxorubicin | decreases response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 protein results in decreased susceptibility to Doxorubicin | CTD | PMID:26317544 |
Mdm2 | Rat | doxorubicin | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of MDM2 mRNA | CTD | PMID:25529476 and PMID:29803840 |
Mdm2 | Rat | doxorubicin | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Doxorubicin results in increased expression of MDM2 mRNA | CTD | PMID:14766674 more ... |
Mdm2 | Rat | doxorubicin | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | pifithrin inhibits the reaction [Doxorubicin results in increased expression of MDM2 mRNA] | CTD | PMID:14766674 |
Mdm2 | Rat | doxorubicin | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Doxorubicin results in increased phosphorylation of MDM2 protein | CTD | PMID:17935137 |
Mdm2 | Rat | eflornithine | decreases expression | EXP | | 6480464 | Eflornithine results in decreased expression of MDM2 mRNA | CTD | PMID:11502571 |
Mdm2 | Rat | ellipticine | decreases response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 promoter SNP results in decreased susceptibility to ellipticine | CTD | PMID:17575151 |
Mdm2 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of MDM2 mRNA | CTD | PMID:29391264 |
Mdm2 | Rat | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of MDM2 mRNA | CTD | PMID:29038839 |
Mdm2 | Rat | epoxiconazole | multiple interactions | EXP | | 6480464 | [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of MDM2 mRNA and [cyproconazole co-treated with epoxiconazole] results in increased expression of MDM2 mRNA | CTD | PMID:29038839 |
Mdm2 | Rat | escitalopram | increases expression | EXP | | 6480464 | Escitalopram results in increased expression of MDM2 mRNA | CTD | PMID:28467792 |
Mdm2 | Rat | ethanol | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Ethanol results in decreased expression of MDM2 mRNA | CTD | PMID:22535522 |
Mdm2 | Rat | ethyl methanesulfonate | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of MDM2 mRNA | CTD | PMID:23649840 |
Mdm2 | Rat | etoposide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Etoposide results in increased expression of MDM2 mRNA more ... | CTD | PMID:16120219 more ... |
Mdm2 | Rat | etoposide | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Etoposide results in decreased expression of MDM2 protein | CTD | PMID:26259609 |
Mdm2 | Rat | etoposide | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Etoposide results in increased phosphorylation of MDM2 protein | CTD | PMID:17935137 and PMID:25744307 |
Mdm2 | Rat | etoposide | increases expression | EXP | | 6480464 | Etoposide results in increased expression of MDM2 protein | CTD | PMID:15459018 |
Mdm2 | Rat | etoposide | multiple interactions | EXP | | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [Etoposide results in increased expression of MDM2 protein] | CTD | PMID:15459018 |
Mdm2 | Rat | etoposide | decreases response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 promoter SNP results in decreased susceptibility to Etoposide | CTD | PMID:17575151 |
Mdm2 | Rat | etoposide | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]] more ... | CTD | PMID:17575151 more ... |
Mdm2 | Rat | EUK-134 | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | EUK-134 inhibits the reaction [Hydrogen Peroxide results in decreased expression of MDM2 protein] and EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of MDM2 protein] | CTD | PMID:25005833 |
Mdm2 | Rat | fenbendazole | increases expression | EXP | | 6480464 | Fenbendazole results in increased expression of MDM2 mRNA | CTD | PMID:23411599 |
Mdm2 | Rat | fenofibrate | decreases expression | EXP | | 6480464 | Fenofibrate results in decreased expression of MDM2 mRNA | CTD | PMID:25596134 |
Mdm2 | Rat | fipronil | increases expression | EXP | | 6480464 | fipronil results in increased expression of MDM2 mRNA | CTD | PMID:23962444 |
Mdm2 | Rat | flavanones | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Flavanones results in increased phosphorylation of MDM2 protein | CTD | PMID:21616090 |
Mdm2 | Rat | flucytosine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Flucytosine results in increased expression of MDM2 protein | CTD | PMID:15592511 |
Mdm2 | Rat | fluoranthene | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Benzo(a)pyrene co-treated with fluoranthene] affects the expression of MDM2 mRNA | CTD | PMID:17690111 |
Mdm2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of MDM2 mRNA | CTD | PMID:24136188 |
Mdm2 | Rat | folic acid | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Folic Acid affects the expression of MDM2 mRNA | CTD | PMID:16361273 |
Mdm2 | Rat | folic acid | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [1 more ... | CTD | PMID:20938992 and PMID:22206623 |
Mdm2 | Rat | formaldehyde | increases expression | EXP | | 6480464 | Formaldehyde results in increased expression of MDM2 mRNA and Formaldehyde results in increased expression of MDM2 protein | CTD | PMID:18045764 |
Mdm2 | Rat | formaldehyde | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of MDM2 mRNA and Formaldehyde results in increased expression of MDM2 protein | CTD | PMID:18045764 and PMID:23649840 |
Mdm2 | Rat | formononetin | increases expression | EXP | | 6480464 | formononetin results in increased expression of MDM2 protein | CTD | PMID:28414026 |
Mdm2 | Rat | FR900359 | decreases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of MDM2 protein | CTD | PMID:37730182 |
Mdm2 | Rat | fumonisin B1 | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA] and fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 protein] | CTD | PMID:18206046 |
Mdm2 | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of MDM2 mRNA | CTD | PMID:22079235 |
Mdm2 | Rat | furosemide | affects expression | EXP | | 6480464 | Furosemide affects the expression of MDM2 mRNA | CTD | PMID:17497460 |
Mdm2 | Rat | ganciclovir | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Ganciclovir results in increased expression of MDM2 protein | CTD | PMID:15592511 |
Mdm2 | Rat | geldanamycin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | geldanamycin results in increased expression of MDM2 mRNA | CTD | PMID:26705709 |
Mdm2 | Rat | gemcitabine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Gemcitabine results in increased expression of MDM2 mRNA | CTD | PMID:17039268 |
Mdm2 | Rat | gemcitabine | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Gemcitabine results in decreased expression of MDM2 mRNA | CTD | PMID:20103597 |
Mdm2 | Rat | genistein | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Genistein results in decreased expression of MDM2 mRNA | CTD | PMID:21048042 |
Mdm2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of MDM2 mRNA | CTD | PMID:22061828 and PMID:33387578 |
Mdm2 | Rat | glyphosate | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Glyphosate results in decreased expression of MDM2 mRNA | CTD | PMID:31295307 |
Mdm2 | Rat | gold atom | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Gold analog results in decreased expression of MDM2 mRNA | CTD | PMID:36057382 |
Mdm2 | Rat | gold(0) | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Gold analog results in decreased expression of MDM2 mRNA | CTD | PMID:36057382 |
Mdm2 | Rat | GW 501516 | multiple interactions | EXP | | 6480464 | MDM2 protein inhibits the reaction [GW 501516 results in increased activity of PPARB protein] | CTD | PMID:19103650 |
Mdm2 | Rat | hydrogen peroxide | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | EUK-134 inhibits the reaction [Hydrogen Peroxide results in decreased expression of MDM2 protein] more ... | CTD | PMID:21552291 and PMID:25005833 |
Mdm2 | Rat | hydrogen peroxide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of MDM2 mRNA | CTD | PMID:21751221 |
Mdm2 | Rat | hydrogen peroxide | increases expression | EXP | | 6480464 | Hydrogen Peroxide results in increased expression of MDM2 mRNA | CTD | PMID:14689451 and PMID:27525270 |
Mdm2 | Rat | hydrogen peroxide | multiple interactions | EXP | | 6480464 | [Quercetin co-treated with Hydrogen Peroxide] results in increased expression of MDM2 mRNA more ... | CTD | PMID:14689451 and PMID:27525270 |
Mdm2 | Rat | hydrogen peroxide | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in decreased expression of MDM2 protein | CTD | PMID:25005833 |
Mdm2 | Rat | hydrogen peroxide | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | Hydrogen Peroxide promotes the reaction [TRP53 protein results in increased expression of MDM2] | CTD | PMID:21552291 |
Mdm2 | Rat | hydroquinone | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | hydroquinone results in increased expression of MDM2 mRNA | CTD | PMID:29221148 |
Mdm2 | Rat | hydroxyurea | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Hydroxyurea results in increased expression of MDM2 mRNA | CTD | PMID:18647660 |
Mdm2 | Rat | hydroxyurea | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Hydroxyurea results in increased expression of MDM2 mRNA | CTD | PMID:16356682 |
Mdm2 | Rat | hydroxyurea | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | Hydroxyurea affects the expression of MDM2 protein | CTD | PMID:16356682 |
Mdm2 | Rat | Icaritin | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | icaritin results in decreased expression of MDM2 protein | CTD | PMID:38431053 |
Mdm2 | Rat | ifosfamide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Ifosfamide results in increased expression of MDM2 mRNA | CTD | PMID:25596134 |
Mdm2 | Rat | Indeno[1,2,3-cd]pyrene | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | indeno(1 more ... | CTD | PMID:32251684 |
Mdm2 | Rat | irinotecan | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Irinotecan metabolite results in increased expression of MDM2 mRNA and Irinotecan results in increased expression of MDM2 mRNA | CTD | PMID:15956246 |
Mdm2 | Rat | isoflurane | decreases expression | EXP | | 6480464 | Isoflurane results in decreased expression of MDM2 mRNA | CTD | PMID:16978161 |
Mdm2 | Rat | kojic acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MDM2 mRNA | CTD | PMID:18544905 |
Mdm2 | Rat | L-ascorbic acid | multiple interactions | EXP | | 6480464 | Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of MDM2 protein] | CTD | PMID:21262251 |
Mdm2 | Rat | L-methionine | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of MDM2 gene | CTD | PMID:20938992 |
Mdm2 | Rat | leflunomide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | leflunomide results in increased expression of MDM2 mRNA | CTD | PMID:28988120 |
Mdm2 | Rat | leptomycin B | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | leptomycin B results in increased expression of MDM2 mRNA | CTD | PMID:20803015 |
Mdm2 | Rat | Leucomalachite green | increases phosphorylation | EXP | | 6480464 | leucomalachite green results in increased phosphorylation of MDM2 protein | CTD | PMID:26558467 |
Mdm2 | Rat | linalool | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | linalool results in increased expression of MDM2 mRNA | CTD | PMID:19922762 |
Mdm2 | Rat | lipopolysaccharide | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | Indirubin E804 inhibits the reaction [Lipopolysaccharides results in increased expression of MDM2 mRNA] | CTD | PMID:23107598 |
Mdm2 | Rat | lipopolysaccharide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of MDM2 mRNA | CTD | PMID:35953652 |
Mdm2 | Rat | lipopolysaccharide | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of MDM2 mRNA | CTD | PMID:10975854 and PMID:23107598 |
Mdm2 | Rat | lupeol | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | lupeol inhibits the reaction [mancozeb results in increased expression of MDM2 mRNA] | CTD | PMID:27235710 |
Mdm2 | Rat | luteolin | increases expression | EXP | | 6480464 | Luteolin results in increased expression of MDM2 mRNA | CTD | PMID:31201582 |
Mdm2 | Rat | luteolin | multiple interactions | EXP | | 6480464 | Luteolin promotes the reaction [Hydrogen Peroxide results in increased expression of MDM2 mRNA] | CTD | PMID:27525270 |
Mdm2 | Rat | LY294002 | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of MDM2 protein | CTD | PMID:16412023 |
Mdm2 | Rat | mancozeb | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | lupeol inhibits the reaction [mancozeb results in increased expression of MDM2 mRNA] | CTD | PMID:27235710 |
Mdm2 | Rat | mancozeb | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | mancozeb results in increased expression of MDM2 mRNA | CTD | PMID:27235710 |
Mdm2 | Rat | manganese atom | multiple interactions | EXP | | 6480464 | [Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein and PPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein] | CTD | PMID:25791630 |
Mdm2 | Rat | manganese atom | decreases expression | EXP | | 6480464 | Manganese results in decreased expression of MDM2 protein | CTD | PMID:25791630 |
Mdm2 | Rat | manganese(0) | decreases expression | EXP | | 6480464 | Manganese results in decreased expression of MDM2 protein | CTD | PMID:25791630 |
Mdm2 | Rat | manganese(0) | multiple interactions | EXP | | 6480464 | [Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein and PPM1D protein inhibits the reaction [[Manganese co-treated with NGF protein] results in decreased expression of MDM2 protein] | CTD | PMID:25791630 |
Mdm2 | Rat | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of MDM2 mRNA | CTD | PMID:28801915 |
Mdm2 | Rat | menadione | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Vitamin K 3 results in decreased expression of MDM2 protein | CTD | PMID:25005833 |
Mdm2 | Rat | menadione | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | EUK-134 inhibits the reaction [Vitamin K 3 results in decreased expression of MDM2 protein] | CTD | PMID:25005833 |
Mdm2 | Rat | mercury dibromide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of MDM2 mRNA | CTD | PMID:26272509 |
Mdm2 | Rat | mercury dibromide | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MDM2 mRNA | CTD | PMID:27188386 |
Mdm2 | Rat | mercury dichloride | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Mercuric Chloride results in decreased expression of MDM2 mRNA | CTD | PMID:23202902 |
Mdm2 | Rat | metformin | increases expression | EXP | | 6480464 | Metformin results in increased expression of MDM2 mRNA | CTD | PMID:25596134 |
Mdm2 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of MDM2 mRNA | CTD | PMID:22584684 |
Mdm2 | Rat | methapyrilene | increases phosphorylation | EXP | | 6480464 | Methapyrilene results in increased phosphorylation of MDM2 protein | CTD | PMID:26558467 |
Mdm2 | Rat | methapyrilene | increases expression | EXP | | 6480464 | Methapyrilene results in increased expression of MDM2 mRNA | CTD | PMID:15890375 more ... |
Mdm2 | Rat | methotrexate | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Methotrexate results in increased activity of and results in increased expression of MDM2 protein more ... | CTD | PMID:21624110 |
Mdm2 | Rat | methotrexate | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | Methotrexate affects the expression of MDM2 mRNA | CTD | PMID:18502557 |
Mdm2 | Rat | methotrexate | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of MDM2 mRNA and Methotrexate results in increased expression of MDM2 protein | CTD | PMID:17637740 more ... |
Mdm2 | Rat | methyl caffeate | affects binding | ISO | MDM2 (Homo sapiens) | 6480464 | methyl caffeate binds to MDM2 protein | CTD | PMID:26415618 |
Mdm2 | Rat | methyl methanesulfonate | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of MDM2 mRNA and Methyl Methanesulfonate results in increased expression of MDM2 protein | CTD | PMID:23649840 and PMID:25078064 |
Mdm2 | Rat | methylarsonic acid | increases expression | EXP | | 6480464 | monomethylarsonic acid results in increased expression of MDM2 mRNA | CTD | PMID:17481689 |
Mdm2 | Rat | methylarsonic acid | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] affects the expression of MDM2 mRNA | CTD | PMID:23192986 |
Mdm2 | Rat | methylmercury chloride | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | methylmercuric chloride results in decreased expression of MDM2 mRNA | CTD | PMID:23202902 |
Mdm2 | Rat | methylmercury chloride | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of MDM2 mRNA | CTD | PMID:28001369 |
Mdm2 | Rat | methylmercury(1+) | multiple interactions | EXP | | 6480464 | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA | CTD | PMID:17905399 |
Mdm2 | Rat | microcystin-LR | decreases expression | EXP | | 6480464 | cyanoginosin LR results in decreased expression of MDM2 protein | CTD | PMID:31157505 |
Mdm2 | Rat | microcystin-LR | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | cyanoginosin LR results in decreased expression of MDM2 mRNA and cyanoginosin LR results in decreased expression of MDM2 protein | CTD | PMID:28414124 |
Mdm2 | Rat | mifepristone | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Mifepristone results in increased expression of MDM2 mRNA | CTD | PMID:12605714 |
Mdm2 | Rat | mitomycin C | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Mitomycin results in increased stability of TP53 protein] which results in increased expression of MDM2 mRNA | CTD | PMID:20536192 |
Mdm2 | Rat | mitomycin C | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Mitomycin results in increased expression of MDM2 protein | CTD | PMID:18096571 |
Mdm2 | Rat | mitomycin C | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Mitomycin results in increased expression of MDM2 mRNA | CTD | PMID:25270620 |
Mdm2 | Rat | mitoxantrone | decreases response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 promoter SNP results in decreased susceptibility to Mitoxantrone | CTD | PMID:17575151 |
Mdm2 | Rat | mono(2-ethylhexyl) phthalate | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of MDM2 protein | CTD | PMID:24706461 |
Mdm2 | Rat | mono(2-ethylhexyl) phthalate | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | mono-(2-ethylhexyl)phthalate results in increased expression of MDM2 mRNA | CTD | PMID:33162236 |
Mdm2 | Rat | monocrotaline | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA | CTD | PMID:21224054 |
Mdm2 | Rat | monosodium L-glutamate | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Fats and Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of MDM2 mRNA | CTD | PMID:23783067 |
Mdm2 | Rat | motexafin gadolinium | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MDM2 mRNA] | CTD | PMID:16357179 |
Mdm2 | Rat | motexafin gadolinium | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | motexafin gadolinium results in increased expression of MDM2 mRNA | CTD | PMID:16357179 |
Mdm2 | Rat | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | N more ... | CTD | PMID:33645215 |
Mdm2 | Rat | N-acetylsphingosine | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | N-acetylsphingosine results in decreased expression of MDM2 mRNA and N-acetylsphingosine results in decreased expression of MDM2 protein | CTD | PMID:18206046 |
Mdm2 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of MDM2 mRNA | CTD | PMID:20061341 |
Mdm2 | Rat | N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Etoposide promotes the reaction [MDM2 protein binds to TOP2A protein]] | CTD | PMID:17575151 |
Mdm2 | Rat | N-ethyl-N-nitrosourea | increases expression | EXP | | 6480464 | Ethylnitrosourea results in increased expression of MDM2 mRNA | CTD | PMID:15954086 |
Mdm2 | Rat | N-ethyl-N-nitrosourea | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Ethylnitrosourea results in increased expression of MDM2 mRNA | CTD | PMID:19100860 |
Mdm2 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Methylnitronitrosoguanidine results in increased expression of MDM2 mRNA | CTD | PMID:12634122 |
Mdm2 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | Cadmium Chloride promotes the reaction [Methylnitronitrosoguanidine results in increased expression of MDM2 protein] | CTD | PMID:12135628 |
Mdm2 | Rat | N-methyl-N'-nitro-N-nitrosoguanidine | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Methylnitronitrosoguanidine results in increased expression of MDM2 protein | CTD | PMID:12135628 |
Mdm2 | Rat | N-methyl-N-nitrosourea | increases expression | EXP | | 6480464 | Methylnitrosourea results in increased expression of MDM2 mRNA | CTD | PMID:28688903 |
Mdm2 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] affects the expression of and affects the localization of MDM2 protein and [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MDM2 mRNA | CTD | PMID:11003613 and PMID:18544905 |
Mdm2 | Rat | N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of MDM2 mRNA and Diethylnitrosamine results in increased expression of MDM2 protein | CTD | PMID:14555611 more ... |
Mdm2 | Rat | N-nitrosodiethylamine | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of MDM2 mRNA] | CTD | PMID:17854601 |
Mdm2 | Rat | N-nitrosodiethylamine | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of MDM2 mRNA and Diethylnitrosamine results in increased expression of MDM2 protein | CTD | PMID:17854601 more ... |
Mdm2 | Rat | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of MDM2 mRNA | CTD | PMID:14600272 and PMID:15890375 |
Mdm2 | Rat | N-nitrosomorpholine | increases expression | EXP | | 6480464 | N-nitrosomorpholine results in increased expression of MDM2 mRNA and N-nitrosomorpholine results in increased expression of MDM2 protein | CTD | PMID:14587038 and PMID:19716841 |
Mdm2 | Rat | N-Vinyl-2-pyrrolidone | multiple interactions | EXP | | 6480464 | [N-vinyl-2-pyrrolidinone binds to N-vinyl-2-pyrrolidinone] which affects the expression of MDM2 mRNA | CTD | PMID:22037397 |
Mdm2 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of MDM2 mRNA | CTD | PMID:24136188 |
Mdm2 | Rat | nickel atom | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Nickel results in increased expression of MDM2 mRNA | CTD | PMID:24068677 |
Mdm2 | Rat | nickel atom | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | TP53 protein affects the reaction [Nickel results in increased expression of MDM2 mRNA] | CTD | PMID:24068677 |
Mdm2 | Rat | nickel dichloride | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | nickel chloride results in increased expression of MDM2 mRNA | CTD | PMID:23566959 and PMID:28552779 |
Mdm2 | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of MDM2 mRNA | CTD | PMID:22546817 |
Mdm2 | Rat | nickel dichloride | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | TP53 protein affects the reaction [nickel chloride results in increased expression of MDM2 mRNA] | CTD | PMID:23566959 |
Mdm2 | Rat | nicotinamide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Niacinamide results in increased expression of MDM2 mRNA | CTD | PMID:16998810 |
Mdm2 | Rat | nicotine | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [[Nicotine results in decreased expression of RPS27A protein] which results in increased phosphorylation of MDM2 protein] which results in increased ubiquitination of TP53 protein and [Nicotine results in decreased expression of RPS27A protein] which results in increased phosphorylation of MDM2 protein | CTD | PMID:30272249 |
Mdm2 | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of MDM2 mRNA | CTD | PMID:24136188 |
Mdm2 | Rat | nitenpyram | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | nitenpyram results in increased expression of MDM2 mRNA | CTD | PMID:35568224 |
Mdm2 | Rat | Nodularin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | nodularin results in increased expression of MDM2 mRNA | CTD | PMID:30562542 |
Mdm2 | Rat | Nutlin-3 | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased expression of MDM2 mRNA more ... | CTD | PMID:16439685 more ... |
Mdm2 | Rat | Nutlin-3 | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | nutlin 3 results in decreased expression of MDM2 protein | CTD | PMID:35213076 |
Mdm2 | Rat | Nutlin-3 | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | nutlin 3 inhibits the reaction [Cisplatin results in increased expression of MDM2 protein] | CTD | PMID:32856486 |
Mdm2 | Rat | Nutlin-3 | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | nutlin 3 results in increased expression of MDM2 mRNA | CTD | PMID:16949053 |
Mdm2 | Rat | Nutlin-3 | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | nutlin 3 results in increased expression of MDM2 mRNA more ... | CTD | PMID:16014563 more ... |
Mdm2 | Rat | O-methyleugenol | increases expression | EXP | | 6480464 | methyleugenol results in increased expression of MDM2 mRNA | CTD | PMID:26011634 |
Mdm2 | Rat | ochratoxin A | increases expression | EXP | | 6480464 | ochratoxin A results in increased expression of MDM2 mRNA | CTD | PMID:23358140 |
Mdm2 | Rat | ochratoxin A | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | ochratoxin A results in decreased expression of MDM2 mRNA | CTD | PMID:30763683 |
Mdm2 | Rat | Octicizer | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 2-ethylhexyldiphenylphosphate results in increased expression of MDM2 mRNA | CTD | PMID:30981936 |
Mdm2 | Rat | ortho-Aminoazotoluene | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | o-Aminoazotoluene results in increased expression of MDM2 mRNA | CTD | PMID:15346788 |
Mdm2 | Rat | ouabain | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Ouabain results in decreased expression of and results in decreased phosphorylation of MDM2 protein | CTD | PMID:31436044 |
Mdm2 | Rat | oxaliplatin | increases expression | EXP | | 6480464 | oxaliplatin results in increased expression of MDM2 mRNA | CTD | PMID:25729387 |
Mdm2 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of MDM2 mRNA | CTD | PMID:25729387 |
Mdm2 | Rat | oxfendazole | decreases phosphorylation | EXP | | 6480464 | oxfendazole results in decreased phosphorylation of MDM2 protein | CTD | PMID:26558467 |
Mdm2 | Rat | oxfendazole | increases expression | EXP | | 6480464 | oxfendazole results in increased expression of MDM2 mRNA | CTD | PMID:26558467 |
Mdm2 | Rat | p-chloromercuribenzoic acid | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of MDM2 mRNA | CTD | PMID:26272509 |
Mdm2 | Rat | p-chloromercuribenzoic acid | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MDM2 mRNA | CTD | PMID:27188386 |
Mdm2 | Rat | paclitaxel | decreases response to substance | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 protein results in decreased susceptibility to Paclitaxel | CTD | PMID:13130078 |
Mdm2 | Rat | palmatine | affects binding | ISO | MDM2 (Homo sapiens) | 6480464 | palmatine binds to MDM2 protein | CTD | PMID:35997646 |
Mdm2 | Rat | paracetamol | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of MDM2 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of MDM2 mRNA] | CTD | PMID:17585979 |
Mdm2 | Rat | paracetamol | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MDM2 mRNA | CTD | PMID:22230336 |
Mdm2 | Rat | paracetamol | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of MDM2 mRNA | CTD | PMID:21420995 |
Mdm2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of MDM2 mRNA | CTD | PMID:21807079 |
Mdm2 | Rat | paracetamol | increases phosphorylation | EXP | | 6480464 | Acetaminophen results in increased phosphorylation of MDM2 protein | CTD | PMID:16330492 |
Mdm2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of MDM2 mRNA | CTD | PMID:17202762 and PMID:33387578 |
Mdm2 | Rat | paracetamol | multiple interactions | EXP | | 6480464 | Acetaminophen promotes the reaction [MDM2 protein binds to TP53 protein] | CTD | PMID:16330492 |
Mdm2 | Rat | paracetamol | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MDM2 mRNA | CTD | PMID:17562736 |
Mdm2 | Rat | paracetamol | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Acetaminophen results in increased expression of MDM2 mRNA | CTD | PMID:26056430 |
Mdm2 | Rat | Paraoxon-methyl | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | methylparaoxon results in increased expression of MDM2 mRNA | CTD | PMID:18418871 |
Mdm2 | Rat | paraquat | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | GPX1 protein affects the reaction [Paraquat affects the expression of MDM2 mRNA] | CTD | PMID:12654481 |
Mdm2 | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of MDM2 mRNA | CTD | PMID:32680482 |
Mdm2 | Rat | paraquat | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Paraquat results in increased expression of MDM2 mRNA | CTD | PMID:20883675 and PMID:34097952 |
Mdm2 | Rat | parathion | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Estradiol co-treated with Parathion] results in increased expression of MDM2 mRNA | CTD | PMID:17622325 |
Mdm2 | Rat | parathion-methyl | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Methyl Parathion results in increased expression of MDM2 mRNA | CTD | PMID:18418871 |
Mdm2 | Rat | PCB138 | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19751709 |
Mdm2 | Rat | PD123319 | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | PD 123319 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA] and PD 123319 inhibits the reaction [AGT protein results in increased expression of MDM2 protein] | CTD | PMID:18206046 |
Mdm2 | Rat | pentachlorophenol | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of MDM2 mRNA | CTD | PMID:23892564 |
Mdm2 | Rat | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of MDM2 mRNA | CTD | PMID:19162173 |
Mdm2 | Rat | phenobarbital | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of MDM2 mRNA | CTD | PMID:19482888 more ... |
Mdm2 | Rat | phenobarbital | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MDM2 mRNA] and NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of MDM2 mRNA] | CTD | PMID:19482888 |
Mdm2 | Rat | phenobarbital | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Phenobarbital results in increased phosphorylation of MDM2 protein | CTD | PMID:19751709 |
Mdm2 | Rat | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of MDM2 mRNA | CTD | PMID:25145657 |
Mdm2 | Rat | phenylmercury acetate | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of MDM2 mRNA | CTD | PMID:26272509 |
Mdm2 | Rat | phenylmercury acetate | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MDM2 mRNA | CTD | PMID:27188386 |
Mdm2 | Rat | phenytoin | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA | CTD | PMID:21224054 |
Mdm2 | Rat | PhIP | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of MDM2 protein | CTD | PMID:15635149 |
Mdm2 | Rat | phlorizin | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Phlorhizin results in decreased expression of MDM2 mRNA | CTD | PMID:22538082 |
Mdm2 | Rat | phosphoramide mustard | increases expression | EXP | | 6480464 | phosphoramide mustard results in increased expression of MDM2 mRNA | CTD | PMID:26708502 |
Mdm2 | Rat | picoxystrobin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | picoxystrobin results in increased expression of MDM2 mRNA | CTD | PMID:33512557 |
Mdm2 | Rat | pifithrin-alpha hydrobromide | multiple interactions | EXP | | 6480464 | pifithrin inhibits the reaction [Arsenic Trioxide results in increased expression of MDM2 mRNA] | CTD | PMID:17487067 |
Mdm2 | Rat | pifithrin-alpha hydrobromide | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | pifithrin inhibits the reaction [Doxorubicin results in increased expression of MDM2 mRNA] and pifithrin inhibits the reaction [Vehicle Emissions results in decreased expression of MDM2 protein] | CTD | PMID:14766674 and PMID:18940243 |
Mdm2 | Rat | piperonyl butoxide | increases expression | EXP | | 6480464 | Piperonyl Butoxide results in increased expression of MDM2 mRNA | CTD | PMID:15890375 and PMID:22484513 |
Mdm2 | Rat | pirinixic acid | multiple interactions | EXP | | 6480464 | MDM2 protein affects the reaction [pirinixic acid results in increased activity of PPARA protein] more ... | CTD | PMID:19103650 |
Mdm2 | Rat | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of MDM2 mRNA | CTD | PMID:15890375 and PMID:19162173 |
Mdm2 | Rat | platycodin D | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | platycodin D results in decreased expression of MDM2 protein | CTD | PMID:25431082 and PMID:27432230 |
Mdm2 | Rat | platycodin D | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 protein inhibits the reaction [platycodin D results in increased expression of FOXO3 protein] | CTD | PMID:25431082 |
Mdm2 | Rat | poly(vinylpyrrolidone) | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Silver co-treated with Povidone] affects the expression of MDM2 protein and [Silver co-treated with Povidone] results in decreased expression of MDM2 mRNA | CTD | PMID:27387714 |
Mdm2 | Rat | potassium bromate | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | potassium bromate results in increased expression of MDM2 mRNA | CTD | PMID:30559759 |
Mdm2 | Rat | potassium dichromate | multiple interactions | EXP | | 6480464 | Ascorbic Acid inhibits the reaction [Potassium Dichromate results in decreased expression of MDM2 protein] | CTD | PMID:21262251 |
Mdm2 | Rat | potassium dichromate | decreases expression | EXP | | 6480464 | Potassium Dichromate results in decreased expression of MDM2 protein | CTD | PMID:21262251 |
Mdm2 | Rat | pravastatin | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Pravastatin results in increased phosphorylation of MDM2 protein | CTD | PMID:15625077 |
Mdm2 | Rat | pravastatin | increases expression | EXP | | 6480464 | Pravastatin results in increased expression of MDM2 protein | CTD | PMID:15625077 |
Mdm2 | Rat | pravastatin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Pravastatin results in increased phosphorylation of MDM2 protein] which results in increased degradation of TP53 protein more ... | CTD | PMID:15625077 |
Mdm2 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of MDM2 mRNA | CTD | PMID:19162173 |
Mdm2 | Rat | prochloraz | multiple interactions | EXP | | 6480464 | [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of MDM2 mRNA | CTD | PMID:29038839 |
Mdm2 | Rat | procymidone | decreases expression | EXP | | 6480464 | procymidone results in decreased expression of MDM2 mRNA | CTD | PMID:15686871 |
Mdm2 | Rat | promethazine | increases phosphorylation | EXP | | 6480464 | Promethazine results in increased phosphorylation of MDM2 protein | CTD | PMID:26558467 |
Mdm2 | Rat | propanal | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of MDM2 mRNA | CTD | PMID:26079696 |
Mdm2 | Rat | PX-866 | decreases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | PX-866 results in decreased phosphorylation of MDM2 protein | CTD | PMID:27017931 |
Mdm2 | Rat | PX-866 | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with PX-866] results in decreased phosphorylation of MDM2 protein | CTD | PMID:27017931 |
Mdm2 | Rat | quercetin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of and results in decreased expression of MDM2 protein | CTD | PMID:17973296 |
Mdm2 | Rat | quercetin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of MDM2 mRNA | CTD | PMID:21632981 more ... |
Mdm2 | Rat | quercetin | multiple interactions | EXP | | 6480464 | [Quercetin co-treated with Hydrogen Peroxide] results in increased expression of MDM2 mRNA | CTD | PMID:27525270 |
Mdm2 | Rat | quercetin | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of MDM2 protein | CTD | PMID:21933852 |
Mdm2 | Rat | quercetin | increases expression | EXP | | 6480464 | Quercetin results in increased expression of MDM2 mRNA | CTD | PMID:31201582 |
Mdm2 | Rat | raloxifene | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with PX-866] results in decreased phosphorylation of MDM2 protein | CTD | PMID:27017931 |
Mdm2 | Rat | reactive oxygen species | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [[[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased phosphorylation of and results in increased stability of TP53 protein] which results in increased expression of MDM2 protein | CTD | PMID:27634759 |
Mdm2 | Rat | resveratrol | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of MDM2 mRNA more ... | CTD | PMID:15542774 more ... |
Mdm2 | Rat | resveratrol | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | resveratrol results in increased expression of MDM2 mRNA | CTD | PMID:15280659 more ... |
Mdm2 | Rat | resveratrol | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [resveratrol results in increased phosphorylation of TRP53 protein] inhibits the reaction [TRP53 protein binds to MDM2 protein] | CTD | PMID:11245472 |
Mdm2 | Rat | resveratrol | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | resveratrol results in decreased expression of MDM2 mRNA and resveratrol results in decreased expression of MDM2 protein | CTD | PMID:16998810 more ... |
Mdm2 | Rat | resveratrol | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | resveratrol results in increased expression of MDM2 mRNA and resveratrol results in increased expression of MDM2 protein | CTD | PMID:11245472 more ... |
Mdm2 | Rat | resveratrol | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | resveratrol affects the expression of MDM2 protein | CTD | PMID:16369916 |
Mdm2 | Rat | rifampicin | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA | CTD | PMID:21224054 |
Mdm2 | Rat | rotenone | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Rotenone results in increased expression of MDM2 mRNA | CTD | PMID:33512557 |
Mdm2 | Rat | ruthenium atom | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Ruthenium results in decreased expression of MDM2 protein | CTD | PMID:17210701 |
Mdm2 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | S-(1 and 2-dichlorovinyl)cysteine results in increased expression of MDM2 mRNA | CTD | PMID:36576512 |
Mdm2 | Rat | SB 431542 | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 |
Mdm2 | Rat | selinexor | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [INCB057643 co-treated with selinexor] results in increased expression of MDM2 protein | CTD | PMID:37899423 |
Mdm2 | Rat | selinexor | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | selinexor results in increased expression of MDM2 protein | CTD | PMID:37899423 |
Mdm2 | Rat | silicon dioxide | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of MDM2 mRNA | CTD | PMID:19073995 |
Mdm2 | Rat | silver atom | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Silver co-treated with Povidone] affects the expression of MDM2 protein and [Silver co-treated with Povidone] results in decreased expression of MDM2 mRNA | CTD | PMID:27387714 |
Mdm2 | Rat | silver atom | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Silver results in decreased expression of MDM2 mRNA | CTD | PMID:26014281 |
Mdm2 | Rat | silver(0) | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [Silver co-treated with Povidone] affects the expression of MDM2 protein and [Silver co-treated with Povidone] results in decreased expression of MDM2 mRNA | CTD | PMID:27387714 |
Mdm2 | Rat | silver(0) | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Silver results in decreased expression of MDM2 mRNA | CTD | PMID:26014281 |
Mdm2 | Rat | simvastatin | increases phosphorylation | ISO | MDM2 (Homo sapiens) | 6480464 | Simvastatin results in increased phosphorylation of MDM2 protein | CTD | PMID:15625077 |
Mdm2 | Rat | simvastatin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Simvastatin promotes the reaction [Benzo(a)pyrene promotes the reaction [TP53 protein binds to MDM2 protein]] | CTD | PMID:15625077 |
Mdm2 | Rat | sirolimus | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | EIF4E protein inhibits the reaction [Sirolimus results in decreased expression of MDM2 protein] more ... | CTD | PMID:15625077 more ... |
Mdm2 | Rat | sirolimus | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Sirolimus results in decreased expression of MDM2 protein | CTD | PMID:19560264 |
Mdm2 | Rat | sodium arsenate | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of MDM2 mRNA | CTD | PMID:11353140 |
Mdm2 | Rat | sodium arsenite | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [sodium arsenite results in increased expression of MDM2 protein] more ... | CTD | PMID:20375080 more ... |
Mdm2 | Rat | sodium arsenite | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of MDM2 mRNA | CTD | PMID:29319823 |
Mdm2 | Rat | sodium arsenite | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | sodium arsenite results in increased expression of MDM2 mRNA | CTD | PMID:11353140 and PMID:20477944 |
Mdm2 | Rat | sodium arsenite | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of MDM2 protein | CTD | PMID:16166651 |
Mdm2 | Rat | sodium arsenite | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of MDM2 mRNA more ... | CTD | PMID:11813266 more ... |
Mdm2 | Rat | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of MDM2 mRNA | CTD | PMID:11960910 and PMID:22110744 |
Mdm2 | Rat | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of MDM2 mRNA | CTD | PMID:25993096 |
Mdm2 | Rat | sorafenib | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | sorafenib results in increased expression of MDM2 mRNA | CTD | PMID:26409325 |
Mdm2 | Rat | staurosporine | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Staurosporine inhibits the reaction [EGF protein inhibits the reaction [resveratrol inhibits the reaction [TP53 protein binds to MDM2 protein]]] | CTD | PMID:15542774 |
Mdm2 | Rat | succimer | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of MDM2 mRNA | CTD | PMID:26378955 |
Mdm2 | Rat | sunitinib | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of MDM2 mRNA | CTD | PMID:31533062 |
Mdm2 | Rat | T-2 toxin | increases expression | EXP | | 6480464 | T-2 Toxin results in increased expression of MDM2 mRNA | CTD | PMID:26141394 |
Mdm2 | Rat | T-2 toxin | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | T-2 Toxin results in increased expression of MDM2 mRNA | CTD | PMID:31863870 |
Mdm2 | Rat | tamoxifen | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of MDM2 mRNA | CTD | PMID:17555576 |
Mdm2 | Rat | tamoxifen | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Tamoxifen results in decreased expression of MDM2 mRNA | CTD | PMID:34821461 |
Mdm2 | Rat | tanespimycin | increases degradation | ISO | MDM2 (Homo sapiens) | 6480464 | tanespimycin results in increased degradation of MDM2 protein | CTD | PMID:17157164 |
Mdm2 | Rat | tauroursodeoxycholic acid | increases expression | EXP | | 6480464 | ursodoxicoltaurine results in increased expression of MDM2 mRNA | CTD | PMID:15885361 |
Mdm2 | Rat | tebufenpyrad | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of MDM2 mRNA | CTD | PMID:33512557 |
Mdm2 | Rat | tert-butyl hydroperoxide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of MDM2 mRNA | CTD | PMID:27509014 |
Mdm2 | Rat | testosterone | decreases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Testosterone results in decreased expression of MDM2 mRNA | CTD | PMID:20403060 |
Mdm2 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of MDM2 mRNA] | CTD | PMID:31150632 |
Mdm2 | Rat | tetrachloromethane | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of MDM2 mRNA | CTD | PMID:31919559 |
Mdm2 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of MDM2 mRNA | CTD | PMID:31150632 |
Mdm2 | Rat | tetraphene | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of MDM2 mRNA | CTD | PMID:27858113 |
Mdm2 | Rat | theaflavin | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [theaflavin co-treated with polylactic acid-polyglycolic acid copolymer analog] inhibits the reaction [9 more ... | CTD | PMID:23717041 |
Mdm2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of MDM2 mRNA | CTD | PMID:18619722 more ... |
Mdm2 | Rat | thioacetamide | increases phosphorylation | EXP | | 6480464 | Thioacetamide results in increased phosphorylation of MDM2 protein | CTD | PMID:26558467 |
Mdm2 | Rat | thymoquinone | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | thymoquinone results in decreased expression of MDM2 protein | CTD | PMID:31433961 and PMID:34627931 |
Mdm2 | Rat | titanium dioxide | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | titanium dioxide results in increased expression of MDM2 mRNA | CTD | PMID:21067279 |
Mdm2 | Rat | titanium dioxide | decreases methylation | ISO | Mdm2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of MDM2 gene | CTD | PMID:35295148 |
Mdm2 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of MDM2 mRNA | CTD | PMID:25729387 |
Mdm2 | Rat | topotecan | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | [N-(oxo-5 more ... | CTD | PMID:23376119 |
Mdm2 | Rat | topotecan | increases expression | EXP | | 6480464 | Topotecan results in increased expression of MDM2 mRNA | CTD | PMID:25729387 |
Mdm2 | Rat | trichloroethene | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | Trichloroethylene affects the expression of MDM2 mRNA | CTD | PMID:21135412 |
Mdm2 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of MDM2 mRNA | CTD | PMID:33387578 |
Mdm2 | Rat | trichloroethene | multiple interactions | EXP | | 6480464 | [Benzene co-treated with methylmercury II co-treated with Trichloroethylene] results in increased expression of MDM2 mRNA | CTD | PMID:17905399 |
Mdm2 | Rat | trichostatin A | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | trichostatin A affects the expression of MDM2 mRNA | CTD | PMID:28542535 |
Mdm2 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of MDM2 mRNA | CTD | PMID:30589522 |
Mdm2 | Rat | triphenyl phosphate | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of MDM2 mRNA | CTD | PMID:37042841 |
Mdm2 | Rat | Triptolide | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | triptolide results in increased expression of MDM2 mRNA | CTD | PMID:32835833 |
Mdm2 | Rat | Triptolide | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | triptolide results in decreased expression of MDM2 protein | CTD | PMID:36990132 |
Mdm2 | Rat | triptonide | affects expression | ISO | Mdm2 (Mus musculus) | 6480464 | triptonide affects the expression of MDM2 mRNA | CTD | PMID:33045310 |
Mdm2 | Rat | trovafloxacin | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [trovafloxacin co-treated with lipopolysaccharide and E coli O55-B5] results in increased expression of MDM2 mRNA | CTD | PMID:18930950 |
Mdm2 | Rat | trovafloxacin | increases expression | ISO | Mdm2 (Mus musculus) | 6480464 | trovafloxacin results in increased expression of MDM2 mRNA | CTD | PMID:35537566 |
Mdm2 | Rat | urethane | multiple interactions | ISO | Mdm2 (Mus musculus) | 6480464 | [Urethane co-treated with Freund's Adjuvant] results in increased expression of MDM2 mRNA | CTD | PMID:12400877 |
Mdm2 | Rat | ursodeoxycholic acid | multiple interactions | EXP | | 6480464 | [Ursodeoxycholic Acid promotes the reaction [TP53 protein binds to MDM2 protein]] which results in increased degradation of TP53 protein more ... | CTD | PMID:14514686 more ... |
Mdm2 | Rat | ursodeoxycholic acid | increases expression | EXP | | 6480464 | Ursodeoxycholic Acid results in increased expression of MDM2 mRNA | CTD | PMID:15885361 |
Mdm2 | Rat | ursodeoxycholic acid | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | MDM2 mutant form inhibits the reaction [Ursodeoxycholic Acid results in increased ubiquitination of TP53 protein] | CTD | PMID:20807506 |
Mdm2 | Rat | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of MDM2 mRNA | CTD | PMID:24136188 |
Mdm2 | Rat | valproic acid | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MDM2 mRNA | CTD | PMID:23179753 |
Mdm2 | Rat | valproic acid | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MDM2 mRNA | CTD | PMID:28001369 |
Mdm2 | Rat | valproic acid | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MDM2 mRNA | CTD | PMID:25979313 |
Mdm2 | Rat | vincristine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Vincristine results in increased expression of MDM2 mRNA | CTD | PMID:23649840 |
Mdm2 | Rat | vincristine | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of MDM2 mRNA | CTD | PMID:16001973 |
Mdm2 | Rat | vorinostat | decreases expression | ISO | MDM2 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of MDM2 mRNA | CTD | PMID:27188386 |
Mdm2 | Rat | wortmannin | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | wortmannin promotes the reaction [Doxorubicin results in increased phosphorylation of MDM2 protein] and wortmannin promotes the reaction [Etoposide results in increased phosphorylation of MDM2 protein] | CTD | PMID:17935137 |
Mdm2 | Rat | zidovudine | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Zidovudine results in increased expression of MDM2 protein | CTD | PMID:16797627 |
Mdm2 | Rat | zinc acetate | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MDM2 mRNA] | CTD | PMID:16357179 |
Mdm2 | Rat | zinc acetate | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | Zinc Acetate results in increased expression of MDM2 mRNA | CTD | PMID:16357179 |
Mdm2 | Rat | zinc atom | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Zinc binds to and results in increased folding of MDM2 protein more ... | CTD | PMID:16965791 |
Mdm2 | Rat | zinc atom | increases ubiquitination | ISO | MDM2 (Homo sapiens) | 6480464 | Zinc results in increased ubiquitination of MDM2 protein | CTD | PMID:16965791 |
Mdm2 | Rat | zinc atom | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Zinc affects the expression of MDM2 protein | CTD | PMID:16636310 |
Mdm2 | Rat | zinc pyrithione | increases expression | ISO | MDM2 (Homo sapiens) | 6480464 | pyrithione zinc results in increased expression of MDM2 mRNA | CTD | PMID:21424779 |
Mdm2 | Rat | zinc(0) | multiple interactions | ISO | MDM2 (Homo sapiens) | 6480464 | Zinc binds to and results in increased folding of MDM2 protein more ... | CTD | PMID:16965791 |
Mdm2 | Rat | zinc(0) | affects expression | ISO | MDM2 (Homo sapiens) | 6480464 | Zinc affects the expression of MDM2 protein | CTD | PMID:16636310 |
Mdm2 | Rat | zinc(0) | increases ubiquitination | ISO | MDM2 (Homo sapiens) | 6480464 | Zinc results in increased ubiquitination of MDM2 protein | CTD | PMID:16965791 |