Actg1 (actin, gamma 1) - Rat Genome Database

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Gene: Actg1 (actin, gamma 1) Rattus norvegicus
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Symbol: Actg1
Name: actin, gamma 1
RGD ID: 1304556
Description: A structural constituent of postsynaptic actin cytoskeleton. Involved in response to calcium ion and response to mechanical stimulus. Is active in postsynaptic actin cytoskeleton and presynaptic actin cytoskeleton. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome 2 and autosomal dominant nonsyndromic deafness 20. Orthologous to human ACTG1 (actin gamma 1); PARTICIPATES IN auditory mechanotransduction pathway; arrhythmogenic right ventricular cardiomyopathy pathway; dilated cardiomyopathy pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: Actg; actin, cytoplasmic 2; actin, gamma, cytoplasmic; actin, gamma, cytoplasmic 1; gamma-actin; LOC287876
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,118,106 - 106,120,951 (-)NCBIGRCr8
mRatBN7.210105,619,738 - 105,622,587 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl372,977,767 - 72,979,694 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl10105,619,737 - 105,624,232 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10110,724,157 - 110,726,999 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,187,175 - 110,190,017 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,540,227 - 105,543,072 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,518,429 - 109,521,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl375,643,054 - 75,644,954 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,519,134 - 109,520,846 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,113,705 - 109,116,103 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,773,489 - 109,776,334 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110109,787,992 - 109,790,826 (-)NCBI
Celera10104,164,981 - 104,167,826 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 11 of 11 rows
Object Symbol
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Original Reference(s)
Actg1Ratautosomal dominant nonsyndromic deafness 20  ISOACTG1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:12519370 more ...
Actg1RatBaraitser-Winter syndrome  ISOACTG1 (Homo sapiens)8554872ClinVar Annotator: match by term: Baraitser-Winter syndromeClinVarPMID:31231230 and PMID:32028042
Actg1RatBaraitser-Winter syndrome 1  ISOACTG1 (Homo sapiens)8554872ClinVar Annotator: match by term: CEREBROOCULOFACIAL LYMPHATIC SYNDROMEClinVarPMID:31231230 and PMID:32028042
Actg1RatBaraitser-Winter syndrome 2  ISOACTG1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:13680526 more ...
Actg1RatCAKUT  ISOACTG1 (Homo sapiens)8554872ClinVar Annotator: match by term: Congenital anomalies of the kidney and urinary tractClinVarPMID:13680526 more ...
Actg1Ratgenetic disease  ISOACTG1 (Homo sapiens)8554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVarPMID:13680526 more ...
Actg1RatHearing Loss  ISOACTG1 (Homo sapiens)8554872ClinVar Annotator: match by term: Hearing impairmentClinVarPMID:19477959 more ...
Actg1Ratintellectual disability  ISOACTG1 (Homo sapiens)8554872ClinVar Annotator: match by term: Intellectual disabilityClinVarPMID:25741868 and PMID:28492532
Actg1Ratlissencephaly  ISOACTG1 (Homo sapiens)8554872ClinVar Annotator: match by term: LissencephalyClinVarPMID:22366783 more ...
Actg1Ratmicrocephaly  ISOACTG1 (Homo sapiens)8554872ClinVar Annotator: match by term: MicrocephalyClinVarPMID:25741868
Actg1Ratnonsyndromic deafness  ISOACTG1 (Homo sapiens)8554872ClinVar Annotator: match by term: Non-syndromic genetic deafnessClinVarPMID:13680526 more ...
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1 to 10 of 10 rows
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Original Reference(s)
Actg1RatAcute Coronary Syndrome  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:21751358
Actg1RatAnimal Mammary Neoplasms  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16316942
Actg1Ratautosomal dominant nonsyndromic deafness 20  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTD 
Actg1Ratcarcinoma  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16316942
Actg1Ratcoloboma  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22366783
Actg1RatCraniofacial Abnormalities  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22366783
Actg1RatExperimental Mammary Neoplasms  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:16316942
Actg1RatNeoplastic Cell Transformation  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:25401301
Actg1RatNervous System Malformations  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:22366783
Actg1Ratosteoporosis  ISOACTG1 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:18924182
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Original Reference(s)
Actg1RatPresbycusis  ISOPOTEI (Homo sapiens)1331525 GAD 
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Original Reference(s)
Actg1Ratautosomal dominant nonsyndromic deafness 20  ISOACTG1 (Homo sapiens)7240710 OMIM 
Actg1RatBaraitser-Winter syndrome 2  ISOACTG1 (Homo sapiens)7240710 OMIM 

1 to 20 of 162 rows

  
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Original Reference(s)
Actg1Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTG1 mRNA]CTDPMID:31150632
Actg1Rat1,2-dichloroethane increases expressionISOActg1 (Mus musculus)6480464ethylene dichloride results in increased expression of ACTG1 mRNACTDPMID:28189721 and PMID:28960355
Actg1Rat1,2-dimethylhydrazine multiple interactionsISOActg1 (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of ACTG1 mRNA]CTDPMID:22206623
Actg1Rat1,2-dimethylhydrazine increases expressionISOActg1 (Mus musculus)64804641 and 2-Dimethylhydrazine results in increased expression of ACTG1 mRNACTDPMID:22206623
Actg1Rat1-naphthyl isothiocyanate increases expressionEXP 64804641-Naphthylisothiocyanate results in increased expression of ACTG1 mRNACTDPMID:30723492
Actg1Rat17alpha-ethynylestradiol increases expressionISOActg1 (Mus musculus)6480464Ethinyl Estradiol results in increased expression of ACTG1 mRNACTDPMID:14976129
Actg1Rat17alpha-ethynylestradiol increases expressionEXP 6480464Ethinyl Estradiol results in increased expression of ACTG1 mRNACTDPMID:12082028
Actg1Rat17beta-estradiol multiple interactionsISOACTG1 (Homo sapiens)64804643 more ...CTDPMID:11179685
Actg1Rat17beta-estradiol increases expressionISOActg1 (Mus musculus)6480464Estradiol results in increased expression of ACTG1 mRNACTDPMID:39298647
Actg1Rat17beta-estradiol decreases expressionISOACTG1 (Homo sapiens)6480464Estradiol results in decreased expression of ACTG1 mRNACTDPMID:11179685
Actg1Rat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expressionISOACTG1 (Homo sapiens)6480464Metribolone results in increased expression of ACTG1 proteinCTDPMID:17152098
Actg1Rat2,2',4,4'-Tetrabromodiphenyl ether affects expressionISOActg1 (Mus musculus)64804642 more ...CTDPMID:30294300
Actg1Rat2,3',4,4',5-Pentachlorobiphenyl increases expressionISOActg1 (Mus musculus)64804642 more ...CTDPMID:31388691
Actg1Rat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOACTG1 (Homo sapiens)6480464Tetrachlorodibenzodioxin promotes the reaction [Estradiol results in decreased expression of ACTG1 mRNA]CTDPMID:11179685
Actg1Rat2,3,7,8-tetrachlorodibenzodioxine affects expressionEXP 6480464Tetrachlorodibenzodioxin affects the expression of ACTG1 mRNACTDPMID:34747641
Actg1Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of ACTG1 proteinCTDPMID:19201780
Actg1Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of ACTG1 mRNA and Tetrachlorodibenzodioxin results in decreased expression of ACTG1 proteinCTDPMID:16054898 more ...
Actg1Rat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISOActg1 (Mus musculus)64804642 more ...CTDPMID:38648751
Actg1Rat2,6-di-tert-butyl-4-methylphenol increases expressionEXP 6480464Butylated Hydroxytoluene results in increased expression of ACTG1 mRNACTDPMID:12082028
Actg1Rat2-hydroxypropanoic acid increases expressionISOACTG1 (Homo sapiens)6480464Lactic Acid results in increased expression of ACTG1 mRNACTDPMID:30851411

1 to 20 of 162 rows

Biological Process
1 to 19 of 19 rows

  
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Original Reference(s)
Actg1Ratangiogenesis acts_upstream_of_or_within_positive_effectISOACTG1 (Homo sapiens)1624291 PMID:25705373RGDPMID:25705373
Actg1Rataxonogenesis involved_inIBAPANTHER:PTN007551913 and Actb (Rattus norvegicus)1600115GO_REF:0000033GO_CentralGO_REF:0000033
Actg1Ratcell motility involved_inIBAPANTHER:PTN007551913 and UniProtKB:P607091600115GO_REF:0000033GO_CentralGO_REF:0000033
Actg1Ratcellular response to type II interferon acts_upstream_of_or_withinISOActg1 (Mus musculus)1624291 PMID:19144319RGDPMID:19144319
Actg1Ratmorphogenesis of a polarized epithelium involved_inISOACTG1 (Homo sapiens)1624291 PMID:22855531RGDPMID:22855531
Actg1Ratplatelet aggregation involved_inISOACTG1 (Homo sapiens)9068941 PMID:23382103UniProtPMID:23382103
Actg1Ratpositive regulation of cell migration involved_inISOACTG1 (Homo sapiens)1624291 PMID:25705373RGDPMID:25705373
Actg1Ratpositive regulation of gene expression involved_inISOACTG1 (Homo sapiens)1624291UniProtKB:P33151 and PMID:25705373RGDPMID:25705373
Actg1Ratpositive regulation of wound healing involved_inISOACTG1 (Homo sapiens)1624291 PMID:25705373RGDPMID:25705373
Actg1Ratpostsynaptic actin cytoskeleton organization involved_inIEAGO:00989731600115GO_REF:0000108GOCGO_REF:0000108
Actg1Ratprotein localization to bicellular tight junction involved_inISOACTG1 (Homo sapiens)1624291UniProtKB:O95832 more ...RGDPMID:22855531
Actg1Ratregulation of focal adhesion assembly involved_inISOACTG1 (Homo sapiens)1624291 PMID:25705373RGDPMID:25705373
Actg1Ratregulation of stress fiber assembly involved_inISOACTG1 (Homo sapiens)1624291 PMID:25705373RGDPMID:25705373
Actg1Ratregulation of synaptic vesicle endocytosis involved_inISOActg1 (Mus musculus)1624291 PMID:27840001RGDPMID:27840001
Actg1Ratregulation of transepithelial transport involved_inISOACTG1 (Homo sapiens)1624291 PMID:22855531RGDPMID:22855531
Actg1Ratresponse to calcium ion  IEP 1598730 RGD 
Actg1Ratresponse to mechanical stimulus  IEP 11541100 RGD 
Actg1Ratsarcomere organization acts_upstream_of_or_withinISOActg1 (Mus musculus)1624291 PMID:15194427RGDPMID:15194427
Actg1Rattight junction assembly involved_inISOACTG1 (Homo sapiens)1624291 PMID:22855531RGDPMID:22855531
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Cellular Component
1 to 20 of 32 rows

  
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Original Reference(s)
Actg1Ratactin cytoskeleton is_active_inIBACGD:CAL0000191211 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Actg1Ratactin cytoskeleton located_inISOActg1 (Mus musculus)1624291 PMID:15194427 and PMID:29891944RGDPMID:15194427 and PMID:29891944
Actg1Ratactin filament located_inISOACTG1 (Homo sapiens)1624291 PMID:28493397RGDPMID:28493397
Actg1Ratactin filament is_active_inIBAMGI:87906 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Actg1Ratapical junction complex located_inISOACTG1 (Homo sapiens)1624291 PMID:22855531RGDPMID:22855531
Actg1Ratapical part of cell located_inISOActg1 (Mus musculus)1624291 PMID:29891944RGDPMID:29891944
Actg1Rataxon is_active_inIBAMGI:87904 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Actg1Ratbasal body patch located_inISOActg1 (Mus musculus)1624291 PMID:29891944RGDPMID:29891944
Actg1Ratcalyx of Held is_active_inISOActg1 (Mus musculus)1624291 PMID:27840001RGDPMID:27840001
Actg1Ratcell-cell junction located_inISOACTG1 (Homo sapiens)1624291 PMID:22855531RGDPMID:22855531
Actg1Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Actg1Ratcytoplasm is_active_inIBAMGI:87904 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Actg1Ratcytoskeleton located_inISSUniProtKB:P607061600115GO_REF:0000024AgBaseGO_REF:0000024
Actg1Ratcytoskeleton located_inIEAUniProtKB-SubCell:SL-00901600115GO_REF:0000044UniProtGO_REF:0000044
Actg1Ratcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
Actg1Ratcytosol located_inTAS 1600115Reactome:R-RNO-433717ReactomeReactome:R-RNO-433717
Actg1Ratdense body located_inISSUniProtKB:P607061600115GO_REF:0000024AgBaseGO_REF:0000024
Actg1Ratextracellular exosome located_inISOACTG1 (Homo sapiens)1624291 PMID:21557262RGDPMID:21557262
Actg1Ratfilamentous actin part_ofISOActg1 (Mus musculus)1624291 PMID:18796539RGDPMID:18796539
Actg1Ratfocal adhesion located_inISSUniProtKB:P607061600115GO_REF:0000024AgBaseGO_REF:0000024
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Molecular Function
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1 to 12 of 12 rows

RGD Manual Annotations


  
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Original Reference(s)
Actg1Ratauditory mechanotransduction pathway   ISOACTG1 (Homo sapiens)9068941 RGDPMID:20624897 and REF_RGD_ID:8547669

Imported Annotations - KEGG (archival)

Object Symbol
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Original Reference(s)
Actg1Ratarrhythmogenic right ventricular cardiomyopathy pathway  IEA 6907045 KEGGrno:05412
Actg1Ratdilated cardiomyopathy pathway  IEA 6907045 KEGGrno:05414
Actg1Rathypertrophic cardiomyopathy pathway  IEA 6907045 KEGGrno:05410
Actg1Ratinfluenza A pathway  IEA 6907045 KEGGrno:05164
Actg1Ratmyocarditis pathway  IEA 6907045 KEGGrno:05416
Actg1Ratphagocytosis pathway  IEA 6907045 KEGGrno:04145

1 to 12 of 12 rows
#
Reference Title
Reference Citation
1. The genetic association database. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. beta-Actin is confined to structures having high capacity of remodelling in developing and adult rat cerebellum. Micheva KD, etal., Eur J Neurosci. 1998 Dec;10(12):3785-98.
5. Possible role of non-muscle alpha-actinins in muscle cell mechanosensitivity. Ogneva IV, etal., PLoS One. 2014 Apr 29;9(4):e96395. doi: 10.1371/journal.pone.0096395. eCollection 2014.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. Role of cytosolic calcium in regulation of cytoskeletal gene expression by insulin. Weinstock RS, etal., Am J Physiol. 1993 Apr;264(4 Pt 1):E519-25.
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PMID:2372296   PMID:2402472   PMID:9334353   PMID:12063253   PMID:12947022   PMID:14760703   PMID:15194427   PMID:16189514   PMID:16502470   PMID:16510873   PMID:17634366   PMID:18796539  
PMID:19013151   PMID:19144319   PMID:19946888   PMID:20458337   PMID:21516116   PMID:21557262   PMID:21630459   PMID:21753002   PMID:22516433   PMID:22855531   PMID:23376485   PMID:23382103  
PMID:23533145   PMID:23580065   PMID:23979707   PMID:25416956   PMID:25705373   PMID:25910212   PMID:27840001   PMID:28259758   PMID:28493397   PMID:29891944  



Actg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr810106,118,106 - 106,120,951 (-)NCBIGRCr8
mRatBN7.210105,619,738 - 105,622,587 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl372,977,767 - 72,979,694 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl10105,619,737 - 105,624,232 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx10110,724,157 - 110,726,999 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.010110,187,175 - 110,190,017 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.010105,540,227 - 105,543,072 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.010109,518,429 - 109,521,288 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl375,643,054 - 75,644,954 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl10109,519,134 - 109,520,846 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.010109,113,705 - 109,116,103 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.410109,773,489 - 109,776,334 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.110109,787,992 - 109,790,826 (-)NCBI
Celera10104,164,981 - 104,167,826 (-)NCBICelera
Cytogenetic Map10q32.3NCBI
ACTG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381781,509,971 - 81,512,799 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1781,509,413 - 81,523,847 (-)EnsemblGRCh38hg38GRCh38
GRCh371779,476,997 - 79,479,825 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361777,091,594 - 77,094,422 (-)NCBINCBI36Build 36hg18NCBI36
Build 341777,091,593 - 77,094,422NCBI
Cytogenetic Map17q25.3NCBI
HuRef1774,925,813 - 74,928,708 (-)NCBIHuRef
CHM1_11779,563,278 - 79,566,173 (-)NCBICHM1_1
T2T-CHM13v2.01782,427,089 - 82,429,917 (-)NCBIT2T-CHM13v2.0
Actg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911120,236,513 - 120,239,321 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11120,236,516 - 120,239,368 (-)EnsemblGRCm39 Ensembl
GRCm3811120,345,687 - 120,348,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11120,345,690 - 120,348,542 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711120,207,004 - 120,209,798 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611120,161,780 - 120,171,339 (-)NCBIMGSCv36mm8
Celera11132,080,255 - 132,083,049 (-)NCBICelera
Cytogenetic Map11E2NCBI
cM Map1184.07NCBI
Actg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555061,546,678 - 1,552,105 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555061,546,678 - 1,549,611 (+)NCBIChiLan1.0ChiLan1.0
ACTG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21998,096,764 - 98,099,674 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan117102,996,909 - 102,999,820 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01775,965,911 - 75,968,822 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11781,668,221 - 81,671,087 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1781,668,221 - 81,671,087 (-)Ensemblpanpan1.1panPan2
ACTG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.19635,978 - 638,328 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl9635,978 - 638,328 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha91,238,649 - 1,241,000 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.091,229,608 - 1,232,436 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl91,229,663 - 1,232,434 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.191,254,519 - 1,256,870 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.091,380,335 - 1,382,686 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.091,460,286 - 1,462,637 (+)NCBIUU_Cfam_GSD_1.0
Actg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244056021,238,788 - 1,241,248 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365945,170,711 - 5,173,247 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365945,170,711 - 5,173,251 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACTG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl121,313,641 - 1,323,217 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1121,320,355 - 1,323,219 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2121,163,186 - 1,166,032 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACTG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11673,456,907 - 73,459,777 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607744,839,199 - 44,842,119 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Actg1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480110,496,718 - 10,499,637 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480110,496,876 - 10,499,737 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Actg1
8 total Variants

Predicted Target Of
Summary Value
Count of predictions:104
Count of miRNA genes:79
Interacting mature miRNAs:91
Transcripts:ENSRNOT00000054976
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 40 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
7387312Bw125Body weight QTL 12530.0047retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight (CMO:0000356)1064890616107211142Rat
12880384Cm107Cardiac mass QTL 1070.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)90404397107211142Rat
12880385Cm108Cardiac mass QTL 1080.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)90404397107211142Rat
1354641Bvd2Brain ventricular dilatation QTL 26.360.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)1093223816107057807Rat
2317029Aia19Adjuvant induced arthritis QTL 192.98joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)1066978955107211142Rat
2303589Bw87Body weight QTL 872body mass (VT:0001259)body weight (CMO:0000012)1081285008107211142Rat
12880396Am13Aortic mass QTL 130.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)1090404397107211142Rat
61449Ciaa2CIA Autoantibody QTL 27.1blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)1063221094107211142Rat
12880398Kidm67Kidney mass QTL 670.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1090404397107211142Rat
61387Bp1Blood pressure QTL 15.1arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1051770177107211142Rat

1 to 10 of 40 rows
PMC138261P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
PMC156330P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1951,258,498 - 51,259,502UniSTS
Celera1213,454,501 - 13,455,354UniSTS
Cytogenetic Map12p11UniSTS
Cytogenetic Map18p12UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map10q32.3UniSTS
PMC201106P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map18p12UniSTS
PMC22644P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
PMC302066P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
PMC97568P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
RH128697  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map18p12UniSTS
PMC156124P2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map12p11UniSTS
Cytogenetic Map10q32.3UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map18p12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
18 22 98 225 174 172 110 50 110 12 421 194 185 83 120 62


1 to 26 of 26 rows
RefSeq Transcripts NM_001127449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CF110974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK364554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK595239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230245 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231979 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 26 of 26 rows

Ensembl Acc Id: ENSRNOT00000054976   ⟹   ENSRNOP00000051859
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,619,737 - 105,622,665 (-)Ensembl
Rnor_6.0 Ensembl10109,519,134 - 109,520,846 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000079310
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl372,977,767 - 72,979,694 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099821   ⟹   ENSRNOP00000096406
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,619,745 - 105,624,232 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108340   ⟹   ENSRNOP00000084530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,619,737 - 105,624,232 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000108494   ⟹   ENSRNOP00000096150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl10105,619,745 - 105,624,232 (-)Ensembl
RefSeq Acc Id: NM_001127449   ⟹   NP_001120921
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr810106,118,106 - 106,120,951 (-)NCBI
mRatBN7.210105,619,742 - 105,622,587 (-)NCBI
Rnor_6.010109,518,433 - 109,521,288 (-)NCBI
Rnor_5.010109,113,705 - 109,116,103 (-)NCBI
RGSC_v3.410109,773,489 - 109,776,334 (-)RGD
Celera10104,164,981 - 104,167,826 (-)RGD
Sequence:
Protein RefSeqs NP_001120921 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM06825 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000096150
  ENSRNOP00000096150.1
GenBank Protein P63259 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001120921   ⟸   NM_001127449
- UniProtKB: P63259 (UniProtKB/Swiss-Prot),   A6HLC1 (UniProtKB/TrEMBL),   A0A8L2QLX4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000051859   ⟸   ENSRNOT00000054976
Ensembl Acc Id: ENSRNOP00000084530   ⟸   ENSRNOT00000108340
Ensembl Acc Id: ENSRNOP00000096406   ⟸   ENSRNOT00000099821
Ensembl Acc Id: ENSRNOP00000096150   ⟸   ENSRNOT00000108494

Name Modeler Protein Id AA Range Protein Structure
AF-P63259-F1-model_v2 AlphaFold P63259 1-375 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 34 of 34 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-22440 BioCyc
Ensembl Genes ENSRNOG00000036701 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00000053452 Ensembl
Ensembl Transcript ENSRNOT00000108494 ENTREZGENE
  ENSRNOT00000108494.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.420.40 UniProtKB/Swiss-Prot
  Actin, Chain A, domain 4 UniProtKB/Swiss-Prot
InterPro Actin UniProtKB/Swiss-Prot
  Actin/actin-like_CS UniProtKB/Swiss-Prot
  Actin_CS UniProtKB/Swiss-Prot
  ATPase_NBD UniProtKB/Swiss-Prot
KEGG Report rno:287876 UniProtKB/Swiss-Prot
NCBI Gene 287876 ENTREZGENE
PANTHER PTHR11937 UniProtKB/Swiss-Prot
Pfam Actin UniProtKB/Swiss-Prot
PhenoGen Actg1 PhenoGen
PRINTS ACTIN UniProtKB/Swiss-Prot
PROSITE ACTINS_1 UniProtKB/Swiss-Prot
  ACTINS_2 UniProtKB/Swiss-Prot
  ACTINS_ACT_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000034254 RatGTEx
  ENSRNOG00000036701 RatGTEx
  ENSRNOG00000053452 RatGTEx
SMART ACTIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF53067 UniProtKB/Swiss-Prot
UniProt A0A8I5ZXG0_RAT UniProtKB/TrEMBL
  A0A8I6AQR0_RAT UniProtKB/TrEMBL
  A0A8L2QLX4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QPT1_RAT UniProtKB/TrEMBL
  A6HLC1 ENTREZGENE, UniProtKB/TrEMBL
  ACTG_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P02571 UniProtKB/Swiss-Prot
  P14104 UniProtKB/Swiss-Prot
  P99022 UniProtKB/Swiss-Prot
1 to 34 of 34 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Actg1  actin, gamma 1  LOC295810  similar to Actin, cytoplasmic 2 (Gamma-actin)  Data merged from RGD:1589770 1643240 APPROVED
2008-08-29 Actg1  actin, gamma 1  Actg1  actin, gamma, cytoplasmic 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC295810  similar to Actin, cytoplasmic 2 (Gamma-actin)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Actg1  actin, gamma, cytoplasmic 1  Actg  actin, gamma, cytoplasmic  Symbol and Name updated 1299863 APPROVED
2005-12-06 Actg  actin, gamma, cytoplasmic  Actg_predicted  actin, gamma, cytoplasmic (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Actg_predicted  actin, gamma, cytoplasmic (predicted)      Symbol and Name status set to approved 70820 APPROVED