Pan2 (poly(A) specific ribonuclease subunit PAN2) - Rat Genome Database

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Gene: Pan2 (poly(A) specific ribonuclease subunit PAN2) Rattus norvegicus
Analyze
Symbol: Pan2
Name: poly(A) specific ribonuclease subunit PAN2
RGD ID: 1303301
Description: Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to contribute to poly(A)-specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to be located in nucleus. Predicted to be part of PAN complex. Predicted to be active in P-body. Orthologous to human PAN2 (poly(A) specific ribonuclease subunit PAN2); PARTICIPATES IN microRNA pathway; RNA degradation pathway; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; endosulfan.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: inactive ubiquitin carboxyl-terminal hydrolase 52; PAB-dependent poly(A)-specific ribonuclease subunit 2; PAB-dependent poly(A)-specific ribonuclease subunit PAN2; PAB1P-dependent poly(A)-nuclease; PAB1P-dependent poly(A)-specific ribonuclease; PAN deadenylation complex catalytic subunit 2; PAN deadenylation complex subunit 2; PAN2 poly(A) specific ribonuclease subunit; PAN2 polyA specific ribonuclease subunit; PAN2 polyA specific ribonuclease subunit homolog; PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae); PAN2-PAN3 deadenylation complex catalytic subunit Pan2; poly(A)-nuclease deadenylation complex subunit 2; ubiquitin specific peptidase 52; ubiquitin specific protease 52; Usp52
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,313,654 - 1,332,252 (+)NCBIGRCr8
mRatBN7.27729,146 - 747,744 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7729,562 - 747,744 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,485,392 - 3,506,344 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,361,374 - 5,382,326 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,664,033 - 5,682,875 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,717,021 - 2,736,541 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,718,700 - 2,736,157 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,696,488 - 2,714,954 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,592,319 - 1,609,170 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,592,318 - 1,609,170 (+)NCBI
Celera7605,467 - 622,256 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IEA)
P-body  (IBA,IEA,ISO)
PAN complex  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. A genomic analysis of rat proteases and protease inhibitors. Puente XS and Lopez-Otin C, Genome Res 2004 Apr;14(4):609-22.
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Wahle E and Winkler GS, Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):561-70. doi: 10.1016/j.bbagrm.2013.01.003. Epub 2013 Jan 19.
Additional References at PubMed
PMID:14583602   PMID:15057822   PMID:18625844  


Genomics

Comparative Map Data
Pan2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,313,654 - 1,332,252 (+)NCBIGRCr8
mRatBN7.27729,146 - 747,744 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7729,562 - 747,744 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,485,392 - 3,506,344 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,361,374 - 5,382,326 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,664,033 - 5,682,875 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,717,021 - 2,736,541 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,718,700 - 2,736,157 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,696,488 - 2,714,954 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,592,319 - 1,609,170 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.171,592,318 - 1,609,170 (+)NCBI
Celera7605,467 - 622,256 (+)NCBICelera
Cytogenetic Map7q11NCBI
PAN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,316,936 - 56,334,000 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,316,223 - 56,334,053 (-)EnsemblGRCh38hg38GRCh38
GRCh371256,710,720 - 56,727,784 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,996,987 - 55,014,017 (-)NCBINCBI36Build 36hg18NCBI36
Build 341254,996,987 - 55,014,017NCBI
Celera1256,362,795 - 56,381,209 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1253,748,483 - 53,766,587 (-)NCBIHuRef
CHM1_11256,677,427 - 56,695,221 (-)NCBICHM1_1
T2T-CHM13v2.01256,284,581 - 56,301,646 (-)NCBIT2T-CHM13v2.0
Pan2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,135,106 - 128,157,227 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,139,204 - 128,157,227 (+)EnsemblGRCm39 Ensembl
GRCm3810128,303,333 - 128,321,358 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,303,335 - 128,321,358 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710127,740,391 - 127,758,403 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,706,284 - 127,724,296 (+)NCBIMGSCv36mm8
Celera10130,691,647 - 130,709,640 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.51NCBI
Pan2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,926,070 - 3,941,506 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,925,356 - 3,946,879 (-)NCBIChiLan1.0ChiLan1.0
PAN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21037,998,405 - 38,015,142 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11237,995,171 - 38,011,908 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,581,728 - 32,598,445 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,835,235 - 32,853,645 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,835,235 - 32,853,645 (+)Ensemblpanpan1.1panPan2
PAN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110621,286 - 636,899 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10621,281 - 634,495 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10684,704 - 700,375 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010629,926 - 645,778 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10629,929 - 644,050 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110607,360 - 623,030 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010850,333 - 866,183 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010974,230 - 989,907 (-)NCBIUU_Cfam_GSD_1.0
Pan2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,132,918 - 58,150,435 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646720,393 - 736,467 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646719,821 - 737,284 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PAN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,712,261 - 21,727,903 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,712,222 - 21,730,528 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,190,220 - 23,204,911 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PAN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,273,867 - 52,290,514 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1152,274,540 - 52,289,410 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037193,696,302 - 193,713,450 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pan2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,669,908 - 11,686,122 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,668,977 - 11,686,840 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pan2
57 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:96
Count of miRNA genes:82
Interacting mature miRNAs:87
Transcripts:ENSRNOT00000050792
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 32 52 36 19 36 1 1 68 33 41 11 1
Low 11 5 5 5 7 10 6 2 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001395705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006240789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005486694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC109891 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BN000323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000050792   ⟹   ENSRNOP00000039314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7729,562 - 747,744 (+)Ensembl
Rnor_6.0 Ensembl72,718,700 - 2,736,157 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097010   ⟹   ENSRNOP00000089136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7729,562 - 746,870 (+)Ensembl
RefSeq Acc Id: NM_001395705   ⟹   NP_001382634
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,655 - 1,332,252 (+)NCBI
mRatBN7.27729,146 - 747,744 (+)NCBI
RefSeq Acc Id: NM_001395706   ⟹   NP_001382635
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,655 - 1,332,252 (+)NCBI
mRatBN7.27729,146 - 747,744 (+)NCBI
RefSeq Acc Id: XM_006240785   ⟹   XP_006240847
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,654 - 1,331,610 (+)NCBI
mRatBN7.27729,146 - 747,103 (+)NCBI
Rnor_6.072,717,021 - 2,735,915 (+)NCBI
Rnor_5.072,696,488 - 2,714,954 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240786   ⟹   XP_006240848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,654 - 1,332,252 (+)NCBI
mRatBN7.27729,146 - 747,744 (+)NCBI
Rnor_6.072,717,021 - 2,736,541 (+)NCBI
Rnor_5.072,696,488 - 2,714,954 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240787   ⟹   XP_006240849
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,654 - 1,332,252 (+)NCBI
mRatBN7.27729,146 - 747,744 (+)NCBI
Rnor_6.072,717,021 - 2,736,541 (+)NCBI
Rnor_5.072,696,488 - 2,714,954 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240788   ⟹   XP_006240850
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,654 - 1,332,252 (+)NCBI
mRatBN7.27729,146 - 747,744 (+)NCBI
Rnor_6.072,717,021 - 2,736,541 (+)NCBI
Rnor_5.072,696,488 - 2,714,954 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006240789   ⟹   XP_006240851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,654 - 1,332,252 (+)NCBI
mRatBN7.27729,146 - 747,744 (+)NCBI
Rnor_6.072,717,021 - 2,736,541 (+)NCBI
Rnor_5.072,696,488 - 2,714,954 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039079715   ⟹   XP_038935643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,314,566 - 1,332,252 (+)NCBI
mRatBN7.27729,182 - 747,744 (+)NCBI
RefSeq Acc Id: XM_063264087   ⟹   XP_063120157
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,654 - 1,332,252 (+)NCBI
RefSeq Acc Id: XM_063264088   ⟹   XP_063120158
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,654 - 1,332,252 (+)NCBI
RefSeq Acc Id: XR_005486693
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,654 - 1,327,469 (+)NCBI
mRatBN7.27729,146 - 742,964 (+)NCBI
RefSeq Acc Id: XR_005486694
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,313,654 - 1,325,995 (+)NCBI
mRatBN7.27729,146 - 742,185 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_006240850   ⟸   XM_006240788
- Peptide Label: isoform X4
- UniProtKB: Q6IE70 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240848   ⟸   XM_006240786
- Peptide Label: isoform X2
- UniProtKB: Q6IE70 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240849   ⟸   XM_006240787
- Peptide Label: isoform X3
- UniProtKB: Q6IE70 (UniProtKB/Swiss-Prot),   R9PXX6 (UniProtKB/TrEMBL),   A6KSB7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240851   ⟸   XM_006240789
- Peptide Label: isoform X7
- UniProtKB: Q6IE70 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006240847   ⟸   XM_006240785
- Peptide Label: isoform X1
- UniProtKB: Q6IE70 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000039314   ⟸   ENSRNOT00000050792
RefSeq Acc Id: XP_038935643   ⟸   XM_039079715
- Peptide Label: isoform X8
- UniProtKB: Q6IE70 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSRNOP00000089136   ⟸   ENSRNOT00000097010
RefSeq Acc Id: NP_001382635   ⟸   NM_001395706
- Peptide Label: isoform 2
- UniProtKB: Q6IE70 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: NP_001382634   ⟸   NM_001395705
- Peptide Label: isoform 1
- UniProtKB: Q6IE70 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063120158   ⟸   XM_063264088
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063120157   ⟸   XM_063264087
- Peptide Label: isoform X5
Protein Domains
Exonuclease   USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6IE70-F1-model_v2 AlphaFold Q6IE70 1-1205 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1303301 AgrOrtholog
BioCyc Gene G2FUF-35378 BioCyc
Ensembl Genes ENSRNOG00000032441 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050792.5 UniProtKB/TrEMBL
  ENSRNOT00000097010.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.420.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cysteine proteinases UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Exonuclease_RNaseT/DNA_pol3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Papain-like_cys_pep_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNaseH-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNaseH_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  USP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:408200 UniProtKB/Swiss-Prot
NCBI Gene 408200 ENTREZGENE
PANTHER DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PAN2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RNase_T UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UCH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pan2 PhenoGen
PROSITE USP_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032441 RatGTEx
SMART EXOIII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53098 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54001 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6GGY1_RAT UniProtKB/TrEMBL
  A6KSB7 ENTREZGENE, UniProtKB/TrEMBL
  PAN2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  R9PXX6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-04 Pan2  poly(A) specific ribonuclease subunit PAN2  Pan2  PAN2 poly(A) specific ribonuclease subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-04-11 Pan2  PAN2 poly(A) specific ribonuclease subunit  Pan2  PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Pan2  PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)  Usp52  ubiquitin specific peptidase 52  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Usp52  ubiquitin specific peptidase 52  Usp52  ubiquitin specific protease 52  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 Usp52  ubiquitin specific protease 52      Symbol and Name status set to approved 1299863 APPROVED
2005-07-14 Usp52  ubiquitin specific protease 52      Symbol and Name status set to provisional 70820 PROVISIONAL