NGDC
Related-
Escherichia coli BL21(DE3) Codon Plus RIL cells
1) norbelladine + S-adenosyl-L-methionine = 4'-O-methylnorbelladine + H+ + S-adenosyl-L-homocysteine
-
2.1.1.336 norbelladine O-methyltransferase.
Bioparts catalyze this reaction
2) norbelladine + S-adenosyl-L-methionine <=> 4'-O-methylnorbelladine + H+ + S-adenosyl-L-homocysteine
-
2.1.1.336 norbelladine O-methyltransferase.
Bioparts catalyze this reaction
3) norbelladine + S-adenosyl-L-methionine => 4'-O-methylnorbelladine + H+ + S-adenosyl-L-homocysteine
-
2.1.1.336 norbelladine O-methyltransferase.
Bioparts catalyze this reaction
Qualitative and quantitative parameters:
Temperature
-
45.0
pH
-
8.8
Taxonomy
Protein sequence
Sequence
Protein family
Nucleotide sequences (Optimized nucleotide sequences according to different chassises)
Sequence
- T Morishige; T Tsujita; Y Yamada; F Sato; . 2000: Molecular characterization of the S-adenosyl-L-methionine:3'-hydroxy-N-methylcoclaurine 4'-O-methyltransferase involved in isoquinoline alkaloid biosynthesis in Coptis japonica. The Journal of Biological Chemistry, 275 23398-405.
- Takashi Morishige; Emilyn Dubouzet; Kum-Boo Choi; Kazufumi Yazaki; Fumihiko Sato; . 2002: Molecular cloning of columbamine O-methyltransferase from cultured Coptis japonica cells. European Journal of Biochemistry, 269 5659-67.
- J D MANN; H M FALES; S H MUDD; . 1963: ALKALOIDS AND PLANT METABOLISM. VI. O-METHYLATION IN VITRO OF NORBELLADINE, A PRECURSOR OF AMARYLLIDACEAE ALKALOIDS. The Journal of Biological Chemistry, 238 3820-3.
- Anan Ounaroon; Gabriele Decker; Jürgen Schmidt; Friedrich Lottspeich; Toni M Kutchan; . 2003: (R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy. The Plant journal : for cell and molecular biology, 36 808-19.
- Nobuhiro Ikezawa; Kinuko Iwasa; Fumihiko Sato; . 2008: Molecular cloning and characterization of CYP80G2, a cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis, from cultured Coptis japonica cells. The Journal of Biological Chemistry, 283 8810-21.
- Peter J Facchini; Vincenzo De Luca; . 2008: Opium poppy and Madagascar periwinkle: model non-model systems to investigate alkaloid biosynthesis in plants. The Plant journal : for cell and molecular biology, 54 763-84.
- Hiromichi Minami; Ju-Sung Kim; Nobuhiro Ikezawa; Tomoya Takemura; Takane Katayama; Hidehiko Kumagai; Fumihiko Sato; . 2008: Microbial production of plant benzylisoquinoline alkaloids. Proceedings of the National Academy of Sciences of the United States of America, 105 7393-8.
- H M Schumacher; M H Zenk; . 1988: Partial purification and characterization of dihydrobenzophenanthridine oxidase from Eschscholtzia californica cell suspension cultures. Plant Cell Reports, 7 43-6.
- Matthew B Kilgore; Megan M Augustin; Courtney M Starks; Mark O'Neil-Johnson; Gregory D May; John A Crow; Toni M Kutchan; . 2014: Cloning and characterization of a norbelladine 4'-O-methyltransferase involved in the biosynthesis of the Alzheimer's drug galanthamine in Narcissus sp. aff. pseudonarcissus. PLoS ONE, 9 e103223.
- Matthew B Kilgore; Megan M Augustin; Gregory D May; John A Crow; Toni M Kutchan; . 2016: CYP96T1 of Narcissus sp. aff. pseudonarcissus Catalyzes Formation of the Para-Para' C-C Phenol Couple in the Amaryllidaceae Alkaloids. Frontiers in Plant Science, 7 225.