The ABCD database: a repository for chemically defined antibodies

Wanessa C Lima; Elisabeth Gasteiger; Paolo Marcatili; Paula Duek; Amos Bairoch; Pierre Cosson

doi:10.1093/nar/gkz714

The ABCD database: a repository for chemically defined antibodies

Nucleic Acids Res. 2020 Jan 8;48(D1):D261-D264. doi: 10.1093/nar/gkz714.

Authors

Wanessa C Lima¹, Elisabeth Gasteiger², Paolo Marcatili³, Paula Duek⁴, Amos Bairoch⁴, Pierre Cosson¹

Affiliations

¹ Geneva Antibody Facility, Faculty of Medicine, University of Geneva, CH-1211 Geneva, Switzerland.
² Swiss-Prot Group, SIB Swiss Institute of Bioinformatics, CH-1211 Geneva, Switzerland.
³ Department of Bio and Health Informatics, Technical University of Denmark, DK-2800 Kongens Lyngby, Denmark.
⁴ CALIPHO Group, Faculty of Medicine, University of Geneva and SIB Swiss Institute of Bioinformatics, CH-1211 Geneva, Switzerland.

Abstract

The ABCD (for AntiBodies Chemically Defined) database is a repository of sequenced antibodies, integrating curated information about the antibody and its antigen with cross-links to standardized databases of chemical and protein entities. It is freely available to the academic community, accessible through the ExPASy server (https://web.expasy.org/abcd/). The ABCD database aims at helping to improve reproducibility in academic research by providing a unique, unambiguous identifier associated to each antibody sequence. It also allows to determine rapidly if a sequenced antibody is available for a given antigen.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Antibodies / chemistry*
Antibodies / immunology
Antigens / chemistry
Antigens / immunology
Databases, Protein*

Substances

Antibodies
Antigens