Chemical_Or_Drug_Is_Metabolized_By_Enzyme
CTRP Terminology
CTRP Agent Terminology
NCI Drug Dictionary Terminology
Efavirenz
154598-52-4
540650
540650
540650
A drug used with other drugs to treat infection with the human immunodeficiency virus (HIV). It blocks HIV from making copies of itself. It is a type of non-nucleoside reverse transcriptase inhibitor and a type of antiviral agent.
A synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity. Efavirenz binds directly to the human immunodeficiency virus type 1 (HIV-1) RT, an RNA-dependent DNA polymerase, blocking its function in viral DNA replication. In combination with other antiretroviral drugs, this agent has been shown to significantly reduce HIV viral load, retarding or preventing damage to the immune system and reducing the risk of developing AIDS. Efavirenz induces activity of the cytochrome P450 system, accelerating its own metabolism.
C0674428
C14H9ClF3NO2
C29027
CHEBI:119486
CTRP
DMP-266
EFAVIRENZ
Efavirenz
Efavirenz
Efavirenz
Efavirenz
FDA
JE6H2O27P8
L743726
MK-0831
Organic Chemical
Pharmacologic Substance
Sustiva
efavirenz
Cytochrome P450 2B6
FDA Established Names and Unique Ingredient Identifier Codes Terminology
Non-nucleoside Reverse Transcriptase Inhibitor