Atp6v0e1 ATPase H+ transporting V0 subunit e1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Atp6v0e1provided by RGD
Official Full Name: ATPase H+ transporting V0 subunit e1provided by RGD
Primary source: RGD:621393
See related: AllianceGenome:RGD:621393
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Atp6k; dsr-1; Dsr-1A; Atp6v0e
Summary: Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in response to amino acid. Predicted to be integral component of membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Orthologous to human ATP6V0E1 (ATPase H+ transporting V0 subunit e1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Adrenal (RPKM 1298.4), Kidney (RPKM 658.2) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q12

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (16984084..17007156, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (16479656..16502732, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (16769857..16792930, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D10RAT121 (e-PCR)
- UniSTS:120644

RH128105 (e-PCR)
- UniSTS:211413

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables proton-transporting ATPase activity, rotational mechanism	IEA Inferred from Electronic Annotation more info
enables proton-transporting ATPase activity, rotational mechanism	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in proton transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in proton transmembrane transport	ISO Inferred from Sequence Orthology more info
involved_in response to amino acid	IEP Inferred from Expression Pattern more info	PubMed
involved_in transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of proton-transporting V-type ATPase complex	ISO Inferred from Sequence Orthology more info
part_of proton-transporting V-type ATPase, V0 domain	IEA Inferred from Electronic Annotation more info
part_of transmembrane transporter complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: V-type proton ATPase subunit e 1

Names: ATPase, H+ transporting, V0 subunit E; ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1; ATPase, H+ transporting, lysosomal V0 subunit E1; ATPase, H+ transporting, lysosomal, V0 subunit e1; D-serine-regulated transcript 1 protein; V-ATPase 9.2 kDa membrane accessory protein; V-ATPase M9.2 subunit; V-ATPase subunit e 1; vacuolar proton pump subunit e 1; vacuolar proton-ATPase subunit M9.2

NP_446030.3

EC 7.1.2.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053578.3 → NP_446030.3 V-type proton ATPase subunit e 1

See identical proteins and their annotated locations for NP_446030.3

Status: VALIDATED

Source sequence(s)

AB037248

UniProtKB/Swiss-Prot

Q794C0

UniProtKB/TrEMBL

A6HDD9

Conserved Domains (1) summary

pfam05493
Location:9 → 67

ATP_synt_H; ATP synthase subunit H