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RPO26 DNA-directed RNA polymerase core subunit RPO26 [ Saccharomyces cerevisiae S288C ]

Gene ID: 856317, updated on 13-Apr-2024

Summary

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Gene symbol
RPO26
Gene description
DNA-directed RNA polymerase core subunit RPO26
Primary source
SGD:S000006391
Locus tag
YPR187W
See related
AllianceGenome:SGD:S000006391
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Saccharomyces cerevisiae S288C (strain: S288C)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Also known as
RPB6
Summary
Contributes to 5'-3' RNA polymerase activity. Involved in tRNA transcription by RNA polymerase III; transcription by RNA polymerase I; and transcription by RNA polymerase II. Part of RNA polymerase I complex; RNA polymerase II, core complex; and RNA polymerase III complex. Orthologous to human POLR2F (RNA polymerase II, I and III subunit F). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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Location:
chromosome: XVI
Exon count:
2
Sequence:
Chromosome: XVI; NC_001148.4 (911257..911800)

Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene serine/threonine protein kinase regulatory subunit ATG13 Neighboring gene Pzf1p Neighboring gene Mlc2p Neighboring gene SKI complex subunit tetratricopeptide repeat protein SKI3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_001148.4

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A shared subunit belongs to the eukaryotic core RNA polymerase. Lanzendörfer M, et al. Genes Dev, 1997 Apr 15. PMID 9136931
  2. Analysis of yeast RNA polymerases with subunit-specific antibodies. Bréant B, et al. J Biol Chem, 1983 Oct 10. PMID 6194159
  3. Spot-immunodetection of conserved determinants in eukaryotic RNA polymerases. Study with antibodies to yeast RNA polymerases subunits. Huet J, et al. J Biol Chem, 1982 Mar 10. PMID 6174508
  4. Multiplexed proteomics mapping of yeast RNA polymerase II and III allows near-complete sequence coverage and reveals several novel phosphorylation sites. Mohammed S, et al. Anal Chem, 2008 May 15. PMID 18416563
  5. Specific interaction and two-dimensional crystallization of histidine tagged yeast RNA polymerase I on nickel-chelating lipids. Bischler N, et al. Biophys J, 1998 Mar. PMID 9512048, Free PMC Article

See all (169) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The global role of Rpo26 in transcription by all nuclear RNA polymerases from its particular ability to act as a dosage suppressor of the cold sensitivity of tgs1Delta cells.
    Title: Two Routes to Genetic Suppression of RNA Trimethylguanosine Cap Deficiency via C-Terminal Truncation of U1 snRNP Subunit Snp1 or Overexpression of RNA Polymerase Subunit Rpo26.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by SGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-directed 5'-3' RNA polymerase activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to RNA polymerase I activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to RNA polymerase II activity IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to RNA polymerase III activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in RNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
involved_in tRNA transcription by RNA polymerase III IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tRNA transcription by RNA polymerase III IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transcription by RNA polymerase I IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription by RNA polymerase I IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in transcription by RNA polymerase III IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA-directed RNA polymerase complex IEA
Inferred from Electronic Annotation
more info
  
part_of RNA polymerase I complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase I complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RNA polymerase II, core complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase II, core complex IDA
Inferred from Direct Assay
more info
 PubMed 
part_of RNA polymerase II, core complex IEA
Inferred from Electronic Annotation
more info
  
part_of RNA polymerase III complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of RNA polymerase III complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
DNA-directed RNA polymerase core subunit RPO26
NP_015513.1
  • RNA polymerase subunit ABC23; common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_001148.4 Reference assembly

    Range
    911257..911800
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001184284.1 → NP_015513.1  TPA: DNA-directed RNA polymerase core subunit RPO26 [Saccharomyces cerevisiae S288C]

    See identical proteins and their annotated locations for NP_015513.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    D6W4I7, P20435
    UniProtKB/TrEMBL
    A6ZX61, B3LKE6, C8ZJL6, G2WPZ8, N1NW71
    Conserved Domains (1) summary
    PLN00152
    Location:70 → 154
    PLN00152; DNA-directed RNA polymerase; Provisional
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
3GTM_F.1
3RZD_F.1
3RZO_F.1
3S14_F.1
3S2D_F.1
3S2H_F.1
4X67_F.1
4X6A_F.1
4Y52_F.1
4Y7N_F.1
5C3E_F.1
5C44_F.1
5C4A_F.1
5C4J_F.1
5C4X_F.1
5LMX_F.1
5M3F_F.1
5M3M_F.1
5M5W_F.1
5N60_F.1
5N61_F.1
5OA1_F.1
5OQJ_F.1
5OQM_F.1
5OT2_F.1
5U5Q_F.1
5VVR_F.1
5VVS_F.1
5W4U_F.1
5W51_F.1
5W5Y_F.1
5W64_F.1
5W65_F.1
5W66_F.1
6BLO_F.1
6BLP_F.1
6BM2_F.1
6BM4_F.1
6BQF_F.1
6CNB_F.1
6CNC_F.1
6CND_F.1
6CNF_F.1
6EU0_F.1
6EU1_F.1
6EU2_F.1
6EU3_F.1
6F40_F.1
6F41_F.1
6F42_F.1
6F44_F.1
6GYL_F.1
6GYM_F.1
6H67_F.1
6H68_F.1
6HKO_F.1
6HLQ_F.1
6HLR_F.1
6HLS_F.1
6I84_F.1
6TUT_F.1
6UPX_F.1
6UPY_F.1
6UPZ_F.1
6UQ0_F.1
6UQ1_F.1
6UQ2_F.1
6UQ3_F.1
7KED_F.1
7KEE_F.1
7KEF_F.1
7O4I_F.1
7O4J_F.1
7O4K_F.1
7O4L_F.1
7O72_F.1
7O73_F.1
7O75_F.1
P20435.1

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