PAO4 polyamine oxidase 4 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Gene symbol: PAO4
Gene description: polyamine oxidase 4
Primary source: Araport:AT1G65840
Locus tag: AT1G65840
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ATPAO4; F1E22.18; F1E22_18; polyamine oxidase 4
Summary: encodes a peroxisomal polyamine oxidase, involved in the back-conversion polyamine degradation pathway. Among the five polyamine oxidases in the Arabidopsis genome, PAO4 is the major isoform in root peroxisomes.
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

The peroxisomal AtPAO4 enzyme plays a role in polyamine catabolism and homeostasis, especially in roots.
Title: A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana.

Submit: New GeneRIF Correction

NM_105256.4

Function	Evidence Code	Pubs
enables N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity	IEA Inferred from Electronic Annotation more info
enables norspermine:oxygen oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables polyamine oxidase activity	IDA Inferred from Direct Assay more info	PubMed
enables spermine:oxygen oxidoreductase (spermidine-forming) activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within polyamine catabolic process	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within polyamine catabolic process	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in spermidine catabolic process	IEA Inferred from Electronic Annotation more info
involved_in spermine catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in peroxisome	IDA Inferred from Direct Assay more info	PubMed

NP_176759.1

polyamine oxidase 4 (PAO4); CONTAINS InterPro DOMAIN/s: Amine oxidase (InterPro:IPR002937), Flavin-containing amine oxidase (InterPro:IPR001613); BEST Arabidopsis thaliana protein match is: polyamine oxidase 3 (TAIR:AT3G59050.1); Has 7028 Blast hits to 6613 proteins in 1153 species: Archae - 127; Bacteria - 2858; Metazoa - 1453; Fungi - 590; Plants - 766; Viruses - 0; Other Eukaryotes - 1234 (source: NCBI BLink).