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Ttn titin [ Rattus norvegicus (Norway rat) ]

Gene ID: 84015, updated on 11-Apr-2024

Summary

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Symbol
Ttnprovided by RGD
Full Name
titinprovided by RGD
Primary source
RGD:621114
See related
Ensembl:ENSRNOG00000069271 AllianceGenome:RGD:621114
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to enable several functions, including cytoskeletal protein binding activity; enzyme binding activity; and protein kinase activity. Predicted to be a structural constituent of muscle. Involved in sarcomere organization. Located in I band. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple) and myopathy (multiple). Orthologous to human TTN (titin). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Muscle (RPKM 25011.4) and Heart (RPKM 6759.1) See more
Orthologs
human mouse all
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Genomic context

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Location:
3q24
Exon count:
337
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (82059648..82332130, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (61652432..61924912, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (63565160..63837815, complement)

Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486119 Neighboring gene pleckstrin homology domain containing A3 Neighboring gene FKBP prolyl isomerase 7 Neighboring gene uncharacterized LOC120101583 Neighboring gene coiled-coil domain containing 141 Neighboring gene SEC14 and spectrin domain containing 1 Neighboring gene RNA, U6 small nuclear 480

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete's Heart. Kellermayer D, et al. Int J Mol Sci, 2021 Oct 15. PMID 34681770, Free PMC Article
  2. Effects of vigorous isometric muscle contraction on titin stiffness-related contractile properties in rat fast-twitch muscles. Shi J, et al. Am J Physiol Regul Integr Comp Physiol, 2021 Dec 1. PMID 34668430
  3. Inhibition of Histone Deacetylases 4 and 5 Reduces Titin Proteolysis and Prevents Reduction of TTN Gene Expression in Atrophied Rat Soleus Muscle after Seven-Day Hindlimb Unloading. Gritsyna YV, et al. Dokl Biochem Biophys, 2020 Nov. PMID 33368047
  4. Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo. Zhou J, et al. Hum Mol Genet, 2019 Jun 15. PMID 30715350
  5. Truncations of the titin Z-disc predispose to a heart failure with preserved ejection phenotype in the context of pressure overload. Ye L, et al. PLoS One, 2018. PMID 30063764, Free PMC Article

See all (77) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins.
    Title: Rbm20 ablation is associated with changes in the expression of titin-interacting and metabolic proteins.
  2. Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete's Heart.
    Title: Increased Expression of N2BA Titin Corresponds to More Compliant Myofibrils in Athlete's Heart.
  3. Effects of vigorous isometric muscle contraction on titin stiffness-related contractile properties in rat fast-twitch muscles.
    Title: Effects of vigorous isometric muscle contraction on titin stiffness-related contractile properties in rat fast-twitch muscles.
  4. Inhibition of Histone Deacetylase 1 Prevents the Decrease in Titin (Connectin) Content and Development of Atrophy in Rat m. soleus after 3-Day Hindlimb Unloading.
    Title: Inhibition of Histone Deacetylase 1 Prevents the Decrease in Titin (Connectin) Content and Development of Atrophy in Rat m. soleus after 3-Day Hindlimb Unloading.
  5. Inhibition of Histone Deacetylases 4 and 5 Reduces Titin Proteolysis and Prevents Reduction of TTN Gene Expression in Atrophied Rat Soleus Muscle after Seven-Day Hindlimb Unloading.
    Title: Inhibition of Histone Deacetylases 4 and 5 Reduces Titin Proteolysis and Prevents Reduction of TTN Gene Expression in Atrophied Rat Soleus Muscle after Seven-Day Hindlimb Unloading.
  6. RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity and Differential Hormonal Responses between Muscles and in Muscle Cell Cultures.
    Title: RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity and Differential Hormonal Responses between Muscles and in Muscle Cell Cultures.
  7. Titin-truncating variants lead to impaired autophagy and mitochondrial function in the heart. These changes not only provide molecular mechanisms that underlie Titin-truncating variants-associated ventricular remodeling but also offer potential targets for its intervention.
    Title: Titin truncations lead to impaired cardiomyocyte autophagy and mitochondrial function in vivo.
  8. In the context of pressure overload, Z-disc TTNtv is associated with cardiac fibrosis, diastolic dysfunction, and capillary rarefaction in the absence of overt systolic dysfunction.
    Title: Truncations of the titin Z-disc predispose to a heart failure with preserved ejection phenotype in the context of pressure overload.
  9. These findings reveal a major signal transduction pathway for insulin-induced titin alternative splicing, and place RBM20 in a central position in the pathway, which is consistent with the reputed role of RBM20 in titin alternative splicing.
    Title: Insulin regulates titin pre-mRNA splicing through the PI3K-Akt-mTOR kinase axis in a RBM20-dependent manner.
  10. Titin-truncating variant is associated with dilated cardiomyopathy.
    Title: Titin-truncating variants affect heart function in disease cohorts and the general population.
Submit: New GeneRIF Correction See all GeneRIFs (44)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables actin filament binding ISO
Inferred from Sequence Orthology
more info
  
enables actinin binding ISO
Inferred from Sequence Orthology
more info
  
enables ankyrin binding ISO
Inferred from Sequence Orthology
more info
  
enables calcium ion binding ISO
Inferred from Sequence Orthology
more info
  
enables calmodulin binding ISO
Inferred from Sequence Orthology
more info
  
enables enzyme binding ISO
Inferred from Sequence Orthology
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
enables muscle alpha-actinin binding ISO
Inferred from Sequence Orthology
more info
  
enables protease binding ISO
Inferred from Sequence Orthology
more info
  
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
enables protein serine/threonine kinase activity ISO
Inferred from Sequence Orthology
more info
  
enables protein tyrosine kinase activity ISO
Inferred from Sequence Orthology
more info
  
enables structural constituent of muscle ISO
Inferred from Sequence Orthology
more info
  
enables structural molecule activity conferring elasticity ISO
Inferred from Sequence Orthology
more info
  
enables telethonin binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within adult heart development ISO
Inferred from Sequence Orthology
more info
  
involved_in cardiac muscle cell development ISO
Inferred from Sequence Orthology
more info
  
involved_in cardiac muscle contraction ISO
Inferred from Sequence Orthology
more info
  
involved_in cardiac muscle hypertrophy ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within cardiac muscle tissue morphogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in cardiac muscle tissue morphogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within cardiac myofibril assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in cardiac myofibril assembly ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within detection of muscle stretch ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within forward locomotion ISO
Inferred from Sequence Orthology
more info
  
involved_in heart development ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within heart growth ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within heart morphogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within in utero embryonic development ISO
Inferred from Sequence Orthology
more info
  
involved_in mitotic chromosome condensation ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within muscle contraction ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of protein secretion ISO
Inferred from Sequence Orthology
more info
  
involved_in protein kinase A signaling ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of relaxation of cardiac muscle ISO
Inferred from Sequence Orthology
more info
  
involved_in response to calcium ion ISO
Inferred from Sequence Orthology
more info
  
involved_in sarcomere organization IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within sarcomere organization ISO
Inferred from Sequence Orthology
more info
  
involved_in sarcomere organization ISO
Inferred from Sequence Orthology
more info
  
involved_in sarcomerogenesis ISO
Inferred from Sequence Orthology
more info
  
involved_in skeletal muscle myosin thick filament assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in skeletal muscle thin filament assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in somitogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within striated muscle cell development ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within ventricular system development ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in A band ISO
Inferred from Sequence Orthology
more info
  
located_in I band IDA
Inferred from Direct Assay
more info
 PubMed 
located_in I band ISO
Inferred from Sequence Orthology
more info
  
located_in M band ISO
Inferred from Sequence Orthology
more info
  
located_in Z disc ISO
Inferred from Sequence Orthology
more info
  
located_in condensed nuclear chromosome ISO
Inferred from Sequence Orthology
more info
  
located_in myofibril IDA
Inferred from Direct Assay
more info
 PubMed 
located_in sarcomere ISO
Inferred from Sequence Orthology
more info
  
located_in striated muscle thin filament ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
titin
Names
titin protein homolog
NP_114457.1
XP_038962312.1
XP_038962313.1
XP_038962314.1
XP_038962315.1
XP_038962316.1
XP_038962317.1
XP_038962319.1
XP_038962321.1
XP_038962328.1
XP_038962330.1
XP_038962331.1
XP_038962333.1
XP_038962334.1
XP_038962335.1
XP_038962336.1
XP_038962337.1
XP_038962340.1
XP_038962341.1
XP_038962343.1
XP_038962344.1
XP_038962345.1
XP_038962346.1
XP_038962348.1
XP_038962349.1
XP_038962351.1
XP_038962352.1
XP_038962353.1
XP_038962354.1
XP_038962356.1
XP_038962357.1
XP_038962358.1
XP_038962359.1
XP_038962360.1
XP_038962361.1
XP_063140759.1
XP_063140760.1
XP_063140761.1
XP_063140763.1
XP_063140764.1
XP_063140765.1
XP_063140766.1
XP_063140767.1
XP_063140769.1
XP_063140770.1
XP_063140771.1
XP_063140772.1
XP_063140773.1
XP_063140775.1
XP_063140776.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_032068.1 → NP_114457.1  titin

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000003

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086021.1 Reference GRCr8

    Range
    82059648..82332130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039106393.2 → XP_038962321.1  titin isoform X12

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (22) summary
    cd05747
    Location:34030 → 34121
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:9986 → 10514
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16970 → 17054
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13943 → 14007
    IG; Immunoglobulin
    smart00410
    Location:12785 → 12849
    IG_like; Immunoglobulin like
    PHA03247
    Location:11442 → 11976
    PHA03247; large tegument protein UL36; Provisional
    COG0810
    Location:10821 → 10890
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    PRK12323
    Location:253 → 346
    PRK12323; DNA polymerase III subunit gamma/tau
    cd00063
    Location:26374 → 26466
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32722 → 32998
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10762 → 10786
    PPAK; PPAK motif
    pfam07679
    Location:7061 → 7150
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12692 → 12760
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9368 → 9398
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23628 → 23709
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:33041 → 33130
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:1992 → 2083
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:12081 → 12387
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  2. XM_063284706.1 → XP_063140776.1  titin isoform X43

  3. XM_039106391.2 → XP_038962319.1  titin isoform X10

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (21) summary
    cd05747
    Location:34042 → 34133
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:33956 → 34584
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16982 → 17066
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13955 → 14019
    IG_like; Immunoglobulin like
    PHA03247
    Location:11454 → 11988
    PHA03247; large tegument protein UL36; Provisional
    COG0810
    Location:10833 → 10902
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    PRK12323
    Location:253 → 346
    PRK12323; DNA polymerase III subunit gamma/tau
    cd00063
    Location:26386 → 26478
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32734 → 33010
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10774 → 10798
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12704 → 12772
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23640 → 23721
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:33053 → 33142
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:12093 → 12399
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  4. XM_039106433.2 → XP_038962361.1  titin isoform X49

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:32652 → 32743
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:15592 → 15676
    FN3; Fibronectin type 3 domain
    smart00409
    Location:12565 → 12629
    IG; Immunoglobulin
    smart00410
    Location:11407 → 11471
    IG_like; Immunoglobulin like
    cd00063
    Location:24996 → 25088
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:31344 → 31620
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10669 → 10693
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:11314 → 11382
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22250 → 22331
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:31663 → 31752
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:10863 → 11193
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  5. XM_063284689.1 → XP_063140759.1  titin isoform X5

  6. XM_039106432.2 → XP_038962360.1  titin isoform X48

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (17) summary
    cd05747
    Location:32847 → 32938
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:15787 → 15871
    FN3; Fibronectin type 3 domain
    smart00410
    Location:12760 → 12824
    IG_like; Immunoglobulin like
    cd00063
    Location:25191 → 25283
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:31539 → 31815
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:11509 → 11577
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22445 → 22526
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:31858 → 31947
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:10808 → 11225
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  7. XM_039106431.2 → XP_038962359.1  titin isoform X47

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:32958 → 33049
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:15898 → 15982
    FN3; Fibronectin type 3 domain
    smart00409
    Location:12871 → 12935
    IG; Immunoglobulin
    smart00410
    Location:11713 → 11777
    IG_like; Immunoglobulin like
    cd00063
    Location:25302 → 25394
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:31650 → 31926
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10864 → 10888
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:11620 → 11688
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22556 → 22637
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:31969 → 32058
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11009 → 11315
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  8. XM_039106430.2 → XP_038962358.1  titin isoform X46

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (18) summary
    cd05747
    Location:33014 → 33105
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:15954 → 16038
    FN3; Fibronectin type 3 domain
    smart00410
    Location:12927 → 12991
    IG_like; Immunoglobulin like
    cd00063
    Location:25358 → 25450
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:31706 → 31982
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10864 → 10888
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:11676 → 11744
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22612 → 22693
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32025 → 32114
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11065 → 11371
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  9. XM_039106429.2 → XP_038962357.1  titin isoform X45

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (18) summary
    cd05747
    Location:33070 → 33161
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16010 → 16094
    FN3; Fibronectin type 3 domain
    smart00409
    Location:12983 → 13047
    IG; Immunoglobulin
    smart00410
    Location:11825 → 11889
    IG_like; Immunoglobulin like
    cd00063
    Location:25414 → 25506
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:31762 → 32038
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:11732 → 11800
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22668 → 22749
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32081 → 32170
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11121 → 11427
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  10. XM_039106428.2 → XP_038962356.1  titin isoform X44

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (18) summary
    cd05747
    Location:33098 → 33189
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16038 → 16122
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13011 → 13075
    IG; Immunoglobulin
    smart00410
    Location:11853 → 11917
    IG_like; Immunoglobulin like
    cd00063
    Location:25442 → 25534
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:31790 → 32066
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:11760 → 11828
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22696 → 22777
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32109 → 32198
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11149 → 11455
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  11. XM_039106389.2 → XP_038962317.1  titin isoform X8

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (21) summary
    cd05747
    Location:34048 → 34139
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16988 → 17072
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13961 → 14025
    IG_like; Immunoglobulin like
    PHA03247
    Location:11460 → 11994
    PHA03247; large tegument protein UL36; Provisional
    COG0810
    Location:10807 → 10909
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    PRK12323
    Location:253 → 346
    PRK12323; DNA polymerase III subunit gamma/tau
    cd00063
    Location:26392 → 26484
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32740 → 33016
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10864 → 10888
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12710 → 12778
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23646 → 23727
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:33059 → 33148
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:12099 → 12405
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  12. XM_039106387.2 → XP_038962315.1  titin isoform X4

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (21) summary
    cd05747
    Location:34050 → 34141
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16990 → 17074
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13963 → 14027
    IG_like; Immunoglobulin like
    PHA03247
    Location:11462 → 11996
    PHA03247; large tegument protein UL36; Provisional
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    PRK12323
    Location:253 → 346
    PRK12323; DNA polymerase III subunit gamma/tau
    cd00063
    Location:26394 → 26486
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32742 → 33018
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12712 → 12780
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23648 → 23729
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:33061 → 33150
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:12101 → 12407
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  13. XM_039106426.2 → XP_038962354.1  titin isoform X42

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (20) summary
    cd05747
    Location:33306 → 33397
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16246 → 16330
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13219 → 13283
    IG; Immunoglobulin
    smart00410
    Location:12061 → 12125
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25650 → 25742
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:31998 → 32274
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:11968 → 12036
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22904 → 22985
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32317 → 32406
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11517 → 11847
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  14. XM_039106421.2 → XP_038962349.1  titin isoform X35

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33417 → 33508
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16357 → 16441
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13330 → 13394
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25761 → 25853
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32109 → 32385
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12079 → 12147
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23015 → 23096
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32428 → 32517
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11468 → 11774
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  15. XM_063284705.1 → XP_063140775.1  titin isoform X40

  16. XM_063284703.1 → XP_063140773.1  titin isoform X39

  17. XM_039106417.2 → XP_038962345.1  titin isoform X29

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33473 → 33564
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16413 → 16497
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13386 → 13450
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25817 → 25909
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32165 → 32441
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12135 → 12203
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23071 → 23152
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32484 → 32573
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11524 → 11830
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  18. XM_039106412.2 → XP_038962340.1  titin isoform X24

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33529 → 33620
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16469 → 16553
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13442 → 13506
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25873 → 25965
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32221 → 32497
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:11434 → 11460
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12191 → 12259
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23127 → 23208
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32540 → 32629
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11580 → 11886
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  19. XM_063284701.1 → XP_063140771.1  titin isoform X34

  20. XM_039106407.2 → XP_038962335.1  titin isoform X21

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33557 → 33648
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:11218 → 11919
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16497 → 16581
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13470 → 13534
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25901 → 25993
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32249 → 32525
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12219 → 12287
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23155 → 23236
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32568 → 32657
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11608 → 11914
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  21. XM_039106425.2 → XP_038962353.1  titin isoform X41

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33332 → 33423
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16272 → 16356
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13245 → 13309
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25676 → 25768
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32024 → 32300
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:11994 → 12062
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22930 → 23011
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32343 → 32432
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11543 → 11873
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  22. XM_039106420.2 → XP_038962348.1  titin isoform X33

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33443 → 33534
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16383 → 16467
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13356 → 13420
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25787 → 25879
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32135 → 32411
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12105 → 12173
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23041 → 23122
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32454 → 32543
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11494 → 11800
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  23. XM_039106415.2 → XP_038962343.1  titin isoform X26

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33499 → 33590
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16439 → 16523
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13412 → 13476
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25843 → 25935
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32191 → 32467
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12161 → 12229
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23097 → 23178
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32510 → 32599
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11550 → 11856
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  24. XM_039106408.2 → XP_038962336.1  titin isoform X22

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (20) summary
    cd05747
    Location:33555 → 33646
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16495 → 16579
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13468 → 13532
    IG; Immunoglobulin
    smart00410
    Location:12310 → 12374
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25899 → 25991
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32247 → 32523
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12217 → 12285
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23153 → 23234
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32566 → 32655
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11606 → 11912
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  25. XM_039106406.2 → XP_038962334.1  titin isoform X20

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (20) summary
    cd05747
    Location:33583 → 33674
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:11219 → 11945
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16523 → 16607
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13496 → 13560
    IG; Immunoglobulin
    smart00410
    Location:12338 → 12402
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25927 → 26019
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32275 → 32551
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12245 → 12313
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23181 → 23262
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32594 → 32683
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11877 → 12130
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  26. XM_039106424.2 → XP_038962352.1  titin isoform X38

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (20) summary
    cd05747
    Location:33360 → 33451
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16300 → 16384
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13273 → 13337
    IG; Immunoglobulin
    smart00410
    Location:12115 → 12179
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25704 → 25796
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32052 → 32328
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12022 → 12090
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22958 → 23039
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32371 → 32460
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11571 → 11901
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  27. XM_039106418.2 → XP_038962346.1  titin isoform X31

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33471 → 33562
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16411 → 16495
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13384 → 13448
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25815 → 25907
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32163 → 32439
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12133 → 12201
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23069 → 23150
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32482 → 32571
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11522 → 11828
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  28. XM_063284702.1 → XP_063140772.1  titin isoform X36

  29. XM_039106413.2 → XP_038962341.1  titin isoform X25

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33527 → 33618
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16467 → 16551
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13440 → 13504
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25871 → 25963
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32219 → 32495
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12189 → 12257
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23125 → 23206
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32538 → 32627
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11578 → 11884
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  30. XM_039106405.2 → XP_038962333.1  titin isoform X19

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (20) summary
    cd05747
    Location:33583 → 33674
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16523 → 16607
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13496 → 13560
    IG; Immunoglobulin
    smart00410
    Location:12338 → 12402
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25927 → 26019
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32275 → 32551
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:11488 → 11514
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12245 → 12313
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23181 → 23262
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32594 → 32683
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11634 → 11940
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  31. XM_063284699.1 → XP_063140769.1  titin isoform X30

  32. XM_039106402.2 → XP_038962330.1  titin isoform X17

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (20) summary
    cd05747
    Location:33611 → 33702
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:11219 → 11973
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16551 → 16635
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13524 → 13588
    IG; Immunoglobulin
    smart00410
    Location:12366 → 12430
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25955 → 26047
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32303 → 32579
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12273 → 12341
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23209 → 23290
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32622 → 32711
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11662 → 11968
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  33. XM_039106423.2 → XP_038962351.1  titin isoform X37

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33385 → 33476
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16325 → 16409
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13298 → 13362
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25729 → 25821
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32077 → 32353
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12047 → 12115
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:22983 → 23064
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32396 → 32485
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11596 → 11926
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  34. XM_039106416.2 → XP_038962344.1  titin isoform X28

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33496 → 33587
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16436 → 16520
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13409 → 13473
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25840 → 25932
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32188 → 32464
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12158 → 12226
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23094 → 23175
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32507 → 32596
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11547 → 11853
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  35. XM_039106409.2 → XP_038962337.1  titin isoform X23

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (20) summary
    cd05747
    Location:33552 → 33643
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16492 → 16576
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13465 → 13529
    IG; Immunoglobulin
    smart00410
    Location:12307 → 12371
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25896 → 25988
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32244 → 32520
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12214 → 12282
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23150 → 23231
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32563 → 32652
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11603 → 11909
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  36. XM_063284700.1 → XP_063140770.1  titin isoform X32

  37. XM_039106403.2 → XP_038962331.1  titin isoform X18

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33608 → 33699
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16548 → 16632
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13521 → 13585
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25952 → 26044
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32300 → 32576
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:11513 → 11539
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12270 → 12338
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23206 → 23287
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32619 → 32708
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11659 → 11965
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  38. XM_063284697.1 → XP_063140767.1  titin isoform X27

  39. XM_039106400.2 → XP_038962328.1  titin isoform X16

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (19) summary
    cd05747
    Location:33636 → 33727
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16576 → 16660
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13549 → 13613
    IG_like; Immunoglobulin like
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    cd00063
    Location:25980 → 26072
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32328 → 32604
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12298 → 12366
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23234 → 23315
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:32647 → 32736
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:11687 → 11993
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  40. XM_063284696.1 → XP_063140766.1  titin isoform X15

  41. XM_063284695.1 → XP_063140765.1  titin isoform X14

  42. XM_063284693.1 → XP_063140763.1  titin isoform X11

  43. XM_063284691.1 → XP_063140761.1  titin isoform X9

  44. XM_039106386.2 → XP_038962314.1  titin isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (21) summary
    cd05747
    Location:34070 → 34161
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:17010 → 17094
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13983 → 14047
    IG_like; Immunoglobulin like
    PHA03247
    Location:11488 → 12022
    PHA03247; large tegument protein UL36; Provisional
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    PRK12323
    Location:253 → 346
    PRK12323; DNA polymerase III subunit gamma/tau
    cd00063
    Location:26414 → 26506
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32762 → 33038
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12732 → 12800
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23668 → 23749
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:33081 → 33170
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:12127 → 12427
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  45. XM_063284690.1 → XP_063140760.1  titin isoform X6

  46. XM_039106388.2 → XP_038962316.1  titin isoform X7

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (22) summary
    cd05747
    Location:34049 → 34140
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:16989 → 17073
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13962 → 14026
    IG; Immunoglobulin
    smart00410
    Location:12804 → 12868
    IG_like; Immunoglobulin like
    PHA03247
    Location:11488 → 12022
    PHA03247; large tegument protein UL36; Provisional
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    PRK12323
    Location:253 → 346
    PRK12323; DNA polymerase III subunit gamma/tau
    cd00063
    Location:26393 → 26485
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32741 → 33017
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12711 → 12779
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23647 → 23728
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:33060 → 33149
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:12127 → 12433
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  47. XM_063284694.1 → XP_063140764.1  titin isoform X13

  48. XM_039106384.2 → XP_038962312.1  titin isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (22) summary
    cd05747
    Location:34076 → 34167
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10032 → 10560
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:17016 → 17100
    FN3; Fibronectin type 3 domain
    smart00409
    Location:13989 → 14053
    IG; Immunoglobulin
    smart00410
    Location:12831 → 12895
    IG_like; Immunoglobulin like
    PHA03247
    Location:11488 → 12022
    PHA03247; large tegument protein UL36; Provisional
    COG0810
    Location:10867 → 10936
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    PRK12323
    Location:253 → 346
    PRK12323; DNA polymerase III subunit gamma/tau
    cd00063
    Location:26420 → 26512
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32768 → 33044
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10808 → 10832
    PPAK; PPAK motif
    pfam07679
    Location:7107 → 7196
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12738 → 12806
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9414 → 9444
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23674 → 23755
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:33087 → 33176
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2038 → 2129
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:12127 → 12433
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain

  49. XM_039106385.2 → XP_038962313.1  titin isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZUN3
    Conserved Domains (21) summary
    cd05747
    Location:34075 → 34166
    IgI_Titin_like; Immunoglobulin (Ig)-like domain of human titin C terminus and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    PTZ00121
    Location:10031 → 10559
    PTZ00121; MAEBL; Provisional
    smart00060
    Location:17015 → 17099
    FN3; Fibronectin type 3 domain
    smart00410
    Location:13988 → 14052
    IG_like; Immunoglobulin like
    PHA03247
    Location:11487 → 12021
    PHA03247; large tegument protein UL36; Provisional
    COG0810
    Location:10866 → 10935
    TonB; Periplasmic protein TonB, links inner and outer membranes [Cell wall/membrane/envelope biogenesis]
    PRK12323
    Location:253 → 346
    PRK12323; DNA polymerase III subunit gamma/tau
    cd00063
    Location:26419 → 26511
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14104
    Location:32767 → 33043
    STKc_Titin; Catalytic domain of the Giant Serine/Threonine Kinase Titin
    pfam02818
    Location:10807 → 10831
    PPAK; PPAK motif
    pfam07679
    Location:7106 → 7195
    I-set; Immunoglobulin I-set domain
    pfam09042
    Location:465 → 504
    Titin_Z; Titin Z
    pfam13927
    Location:12737 → 12805
    Ig_3; Immunoglobulin domain
    pfam18362
    Location:9413 → 9443
    THB; Tri-helix bundle domain
    cd00096
    Location:103 → 106
    Ig; Ig strand A [structural motif]
    cd05748
    Location:23673 → 23754
    Ig_Titin_like; Immunoglobulin (Ig)-like domain of titin and similar proteins
    cd20927
    Location:33086 → 33175
    IgI_Titin_M1-like; Immunoglobulin-like M1 domain from Titin; a member of the I-set of IgSF domains
    cd20951
    Location:2037 → 2128
    IgI_titin_I1-like; Immunoglobulin domain I1 of the titin I-band and similar proteins; a member of the I-set of IgSF domains
    cd20974
    Location:6 → 98
    IgI_1_Titin_Z1z2-like; First Ig-like domain of the giant muscle protein titin Z1z2 in the sarcomeric Z-disk and similar proteins; a member of the I-set of IgSF domains
    NF033839
    Location:12126 → 12432
    PspC_subgroup_2; pneumococcal surface protein PspC, LPXTG-anchored form
    cl11960
    Location:103 → 193
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

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