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PAL3 phenyl alanine ammonia-lyase 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 830302, updated on 6-Oct-2023

Summary

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Gene symbol
PAL3
Gene description
phenyl alanine ammonia-lyase 3
Primary source
Araport:AT5G04230
Locus tag
AT5G04230
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATPAL3; F21E1.150; F21E1_150; phenyl alanine ammonia-lyase 3
Summary
Member of Phenylalanine ammonialyase (PAL) gene family. Differs significantly from PAL1 and PAL2 and other sequenced plant PAL genes. Arabidopsis has four PALs: AT2G37040 (PAL1), AT3G53260 (PAL2), AT5G04230 (PAL3) and AT3G10340 (PAL4).
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Genomic context

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Location:
chromosome: 5
Exon count:
3
Sequence:
Chromosome: 5; NC_003076.8 (1160569..1163957)

Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene CCCH-type zinc fingerfamily protein with RNA-binding domain-containing protein Neighboring gene Calcium-dependent lipid-binding (CaLB domain) family protein Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Zinc finger (C2H2 type) family protein / transcription factor jumonji (jmj) family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003076.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The phenylalanine ammonia-lyase gene family in Arabidopsis thaliana. Wanner LA, et al. Plant Mol Biol, 1995 Jan. PMID 7888622
  2. Arabidopsis Kelch repeat F-box proteins regulate phenylpropanoid biosynthesis via controlling the turnover of phenylalanine ammonia-lyase. Zhang X, et al. Plant Cell, 2013 Dec. PMID 24363316, Free PMC Article
  3. Down-regulation of Kelch domain-containing F-box protein in Arabidopsis enhances the production of (poly)phenols and tolerance to ultraviolet radiation. Zhang X, et al. Plant Physiol, 2015 Feb. PMID 25502410, Free PMC Article
  4. Mapping the signaling network of BIN2 kinase using TurboID-mediated biotin labeling and phosphoproteomics. Kim TW, et al. Plant Cell, 2023 Mar 15. PMID 36660928, Free PMC Article
  5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001203294.1
NM_120505.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables phenylalanine ammonia-lyase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cinnamic acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within defense response TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within response to wounding TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
phenyl alanine ammonia-lyase 3
NP_001190223.1
  • phenyl alanine ammonia-lyase 3 (PAL3); FUNCTIONS IN: phenylalanine ammonia-lyase activity; INVOLVED IN: response to wounding, defense response; LOCATED IN: cytoplasm; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phenylalanine/histidine ammonia-lyase (InterPro:IPR001106), Phenylalanine/histidine ammonia-lyases, active site (InterPro:IPR022313), L-Aspartase-like (InterPro:IPR008948), Phenylalanine ammonia-lyase (InterPro:IPR005922); BEST Arabidopsis thaliana protein match is: phenylalanine ammonia-lyase 4 (TAIR:AT3G10340.1).
NP_196043.2
  • phenyl alanine ammonia-lyase 3 (PAL3); FUNCTIONS IN: phenylalanine ammonia-lyase activity; INVOLVED IN: response to wounding, defense response; LOCATED IN: cytoplasm; EXPRESSED IN: 21 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phenylalanine/histidine ammonia-lyase (InterPro:IPR001106), Phenylalanine/histidine ammonia-lyases, active site (InterPro:IPR022313), L-Aspartase-like (InterPro:IPR008948), Phenylalanine ammonia-lyase (InterPro:IPR005922); BEST Arabidopsis thaliana protein match is: phenylalanine ammonia-lyase 4 (TAIR:AT3G10340.1); Has 4848 Blast hits to 4828 proteins in 1399 species: Archae - 40; Bacteria - 2936; Metazoa - 80; Fungi - 127; Plants - 1170; Viruses - 0; Other Eukaryotes - 495 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003076.8 Reference assembly

    Range
    1160569..1163957
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_120505.4 → NP_196043.2  phenyl alanine ammonia-lyase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_196043.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P45725, Q53YP2, Q9FYD8
    UniProtKB/TrEMBL
    A0A178ULH7, A0A5S9Y3H1
    Conserved Domains (2) summary
    PLN02457
    Location:9 → 694
    PLN02457; phenylalanine ammonia-lyase
    pfam00221
    Location:49 → 530
    Lyase_aromatic; Aromatic amino acid lyase

  2. NM_001203294.1 → NP_001190223.1  phenyl alanine ammonia-lyase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001190223.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A178ULH7, A0A5S9Y3H1, F4JW69
    Conserved Domains (2) summary
    PLN02457
    Location:9 → 698
    PLN02457; phenylalanine ammonia-lyase
    pfam00221
    Location:49 → 534
    Lyase_aromatic; Aromatic amino acid lyase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P45725.3

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