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PAO3 polyamine oxidase 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 825074, updated on 7-Sep-2023

Summary

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Gene symbol
PAO3
Gene description
polyamine oxidase 3
Primary source
Araport:AT3G59050
Locus tag
AT3G59050
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATPAO3; polyamine oxidase 3
Summary
Encodes a polyamine oxidase.
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Genomic context

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Location:
chromosome: 3
Exon count:
9
Sequence:
Chromosome: 3; NC_003074.8 (21824696..21827509, complement)

Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene MATE efflux family protein Neighboring gene Tetratricopeptide repeat (TPR)-like superfamily protein Neighboring gene ncRNA Neighboring gene phytochrome interacting factor 3-like 6 Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. GUS Reporter-Aided Promoter Deletion Analysis of A. thaliana POLYAMINE OXIDASE 3. Podia V, et al. Int J Mol Sci, 2023 Jan 24. PMID 36768644, Free PMC Article
  2. Spermidine oxidase-derived H₂O₂ regulates pollen plasma membrane hyperpolarization-activated Ca(2+) -permeable channels and pollen tube growth. Wu J, et al. Plant J, 2010 Sep. PMID 20626657
  3. Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back-conversion pathway in Arabidopsis. Moschou PN, et al. Plant Physiol, 2008 Aug. PMID 18583528, Free PMC Article
  4. Characterization of five polyamine oxidase isoforms in Arabidopsis thaliana. Takahashi Y, et al. Plant Cell Rep, 2010 Sep. PMID 20532512
  5. An abscisic acid-responsive protein interaction network for sucrose non-fermenting related kinase1 in abiotic stress response. Carianopol CS, et al. Commun Biol, 2020 Mar 26. PMID 32218501, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Pollen from two mutants lacking expression of AtPAO3 was unable to induce the opening of the Ca(2+) -permeable channels in the presence of Spd, resulting in reduced pollen tube growth and seed number.
    Title: Spermidine oxidase-derived H₂O₂ regulates pollen plasma membrane hyperpolarization-activated Ca(2+) -permeable channels and pollen tube growth.
  2. AtPAO3 catalyzes the sequential conversion/oxidation of spermine to spermidine, and of spermidine to putrescine, thus exhibiting functional homology to the mammalian PAOs.
    Title: Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back-conversion pathway in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Miscellaneous features

  • Loc: c21827383-21827177 AT3G59050.uORF1
NM_115767.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity IEA
Inferred from Electronic Annotation
more info
  
enables N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity IEA
Inferred from Electronic Annotation
more info
  
enables polyamine oxidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity IEA
Inferred from Electronic Annotation
more info
  
enables spermine oxidase (propane-1,3-diamine-forming) activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables spermine:oxygen oxidoreductase (spermidine-forming) activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within polyamine catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in spermidine catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in spermine catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  
located_in peroxisome IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
polyamine oxidase 3
NP_191464.1
  • polyamine oxidase 3 (PAO3); CONTAINS InterPro DOMAIN/s: Amine oxidase (InterPro:IPR002937), Flavin-containing amine oxidase (InterPro:IPR001613); BEST Arabidopsis thaliana protein match is: polyamine oxidase 2 (TAIR:AT2G43020.1); Has 6641 Blast hits to 6191 proteins in 1102 species: Archae - 131; Bacteria - 2618; Metazoa - 1408; Fungi - 589; Plants - 766; Viruses - 0; Other Eukaryotes - 1129 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003074.8 Reference assembly

    Range
    21824696..21827509 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_115767.3 → NP_191464.1  polyamine oxidase 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_191464.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8LE44, Q9LYT1
    UniProtKB/TrEMBL
    A0A5S9XM40, A0A654FJ44
    Conserved Domains (1) summary
    PLN02268
    Location:29 → 463
    PLN02268; probable polyamine oxidase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9LYT1.1

Gene LinkOut

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