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PAO2 polyamine oxidase 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 818904, updated on 7-Sep-2023

Summary

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Gene symbol
PAO2
Gene description
polyamine oxidase 2
Primary source
Araport:AT2G43020
Locus tag
AT2G43020
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATPAO2; MFL8.12; MFL8_12; polyamine oxidase 2
Summary
Encodes a polyamine oxidase.
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Genomic context

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Location:
chromosome: 2
Exon count:
9
Sequence:
Chromosome: 2; NC_003071.7 (17891503..17894635)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene phytochrome interacting factor 4 Neighboring gene Ribosomal protein L3 family protein Neighboring gene tetratricopeptide repeat (TPR)-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Polyamine oxidase 2 is involved in regulating excess spermidine contents during seed germination and early seedling development in Arabidopsis thaliana. Takahashi Y, et al. Biochem Biophys Res Commun, 2019 Sep 3. PMID 31301766
  2. Arabidopsis Polyamine oxidase-2 uORF is required for downstream translational regulation. Guerrero-González ML, et al. Plant Physiol Biochem, 2016 Nov. PMID 27526386
  3. Decrease of Arabidopsis PAO activity entails increased RBOH activity, ROS content and altered responses to Pseudomonas. Jasso-Robles FI, et al. Plant Sci, 2020 Mar. PMID 32005378
  4. Characterization of five polyamine oxidase isoforms in Arabidopsis thaliana. Takahashi Y, et al. Plant Cell Rep, 2010 Sep. PMID 20532512
  5. Arabidopsis thaliana AHL family modulates hypocotyl growth redundantly by interacting with each other via the PPC/DUF296 domain. Zhao J, et al. Proc Natl Acad Sci U S A, 2013 Nov 26. PMID 24218605, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Decrease of Arabidopsis PAO activity entails increased RBOH activity, ROS content and altered responses to Pseudomonas.
    Title: Decrease of Arabidopsis PAO activity entails increased RBOH activity, ROS content and altered responses to Pseudomonas.
  2. AtPAO2 appears to be involved in excess spermidine catabolism during seed germination and early seedling development irrespective of subcellular localization
    Title: Polyamine oxidase 2 is involved in regulating excess spermidine contents during seed germination and early seedling development in Arabidopsis thaliana.
  3. PAO2 upstream open reading frame causes translational repression of the downstream down stream open reading frames.
    Title: Arabidopsis Polyamine oxidase-2 uORF is required for downstream translational regulation.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Miscellaneous features

  • Loc: 17891767-17891934 AT2G43020.uORF1
NM_129863.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables polyamine oxidase activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within polyamine catabolic process IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in spermidine catabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in spermine catabolic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrion ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
polyamine oxidase 2
NP_181830.1
  • polyamine oxidase 2 (PAO2); FUNCTIONS IN: primary amine oxidase activity, oxidoreductase activity; INVOLVED IN: oxidation reduction; LOCATED IN: cellular_component unknown; EXPRESSED IN: sperm cell, male gametophyte, pollen tube; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: Amine oxidase (InterPro:IPR002937), Flavin-containing amine oxidase (InterPro:IPR001613); BEST Arabidopsis thaliana protein match is: polyamine oxidase 3 (TAIR:AT3G59050.1); Has 6381 Blast hits to 5960 proteins in 1057 species: Archae - 96; Bacteria - 2371; Metazoa - 1412; Fungi - 575; Plants - 752; Viruses - 0; Other Eukaryotes - 1175 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    17891503..17894635
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_129863.3 → NP_181830.1  polyamine oxidase 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_181830.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8S9L4, Q9SKX5
    UniProtKB/TrEMBL
    A0A5S9X6S4, A0A654F1E0, A0A7G2EDD9
    Conserved Domains (1) summary
    PLN02268
    Location:41 → 462
    PLN02268; probable polyamine oxidase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SKX5.1

Gene LinkOut

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