nkd2b NKD inhibitor of WNT signaling pathway 2b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nkd2bprovided by ZNC
Official Full Name: NKD inhibitor of WNT signaling pathway 2bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-081013-6
See related: Ensembl:ENSDARG00000055271 AllianceGenome:ZFIN:ZDB-GENE-081013-6
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: nkd2; nkd2a; nkd2l
Summary: Predicted to enable calcium ion binding activity. Predicted to be involved in negative regulation of Wnt signaling pathway. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm. Orthologous to human NKD2 (NKD inhibitor of WNT signaling pathway 2). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (52999980..53054838)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (53112206..53167064)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within Wnt signaling pathway	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of Wnt signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
involved_in negative regulation of canonical Wnt signaling pathway	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein naked cuticle homolog 2-like

Names: NKD2, WNT signaling pathway inhibitor b; naked 2a; naked cuticle homolog 2; naked cuticle homolog 2b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.