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gfra1b gdnf family receptor alpha 1b [ Danio rerio (zebrafish) ]

Gene ID: 79377, updated on 27-Mar-2024

Summary

Official Symbol
gfra1bprovided by ZNC
Official Full Name
gdnf family receptor alpha 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-010226-3
See related
Ensembl:ENSDARG00000102564 AllianceGenome:ZFIN:ZDB-GENE-010226-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
gfralpha1b
Summary
Predicted to enable signaling receptor activity. Acts upstream of or within enteric nervous system development. Predicted to be located in plasma membrane. Predicted to be anchored component of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in nervous system; presumptive enteric nervous system; pronephric duct; and vagal neural crest. Orthologous to human GFRA1 (GDNF family receptor alpha 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

Location:
chromosome: 12
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (29763656..29818209)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (29648754..29703307)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene SH2 domain containing 4Bb Neighboring gene neuregulin 3b Neighboring gene uncharacterized LOC108191725 Neighboring gene attractin-like 1b Neighboring gene TruB pseudouridine (psi) synthase family member 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within enteric nervous system development IGI
Inferred from Genetic Interaction
more info
PubMed 
involved_in nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in external side of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
GDNF family receptor alpha-1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131731.1NP_571806.1  GDNF family receptor alpha-1b precursor

    See identical proteins and their annotated locations for NP_571806.1

    Status: PROVISIONAL

    Source sequence(s)
    AY436321
    UniProtKB/TrEMBL
    Q98TT8
    Related
    ENSDARP00000137090.1, ENSDART00000161533.2
    Conserved Domains (2) summary
    smart00907
    Location:41123
    GDNF; GDNF/GAS1 domain
    pfam02351
    Location:255349
    GDNF; GDNF/GAS1 domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    29763656..29818209
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394850.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    181771..182684
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)