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aldoca aldolase C, fructose-bisphosphate, a [ Danio rerio (zebrafish) ]

Gene ID: 792692, updated on 27-Mar-2024

Summary

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Official Symbol
aldocaprovided by ZNC
Official Full Name
aldolase C, fructose-bisphosphate, aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050706-128
See related
Ensembl:ENSDARG00000057661 AllianceGenome:ZFIN:ZDB-GENE-050706-128
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
aldocl; wu:fj56h04; zgc:112357
Summary
Predicted to enable fructose-bisphosphate aldolase activity. Predicted to be involved in fructose 1,6-bisphosphate metabolic process and glycolytic process. Predicted to be active in cytosol. Is expressed in brain. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system. Orthologous to human ALDOC (aldolase, fructose-bisphosphate C). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 15
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (16079586..16098156, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (16143564..16162134, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene dynein, light chain, LC8-type 2a Neighboring gene serine and arginine rich splicing factor 1a Neighboring gene ribosomal protein S6 kinase related a Neighboring gene si:ch211-259g3.4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Functionally distinct Purkinje cell types show temporal precision in encoding locomotion. Chang W, et al. Proc Natl Acad Sci U S A, 2020 Jul 21. PMID 32632015, Free PMC Article
  2. Establishment of Gal4 transgenic zebrafish lines for analysis of development of cerebellar neural circuitry. Takeuchi M, et al. Dev Biol, 2015 Jan 1. PMID 25300581
  3. Involvement of Cerebellar Neural Circuits in Active Avoidance Conditioning in Zebrafish. Koyama W, et al. eNeuro, 2021 May-Jun. PMID 33952613, Free PMC Article
  4. Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking. Sanderson LE, et al. Brain, 2021 Apr 12. PMID 33764426, Free PMC Article
  5. Tracing of Afferent Connections in the Zebrafish Cerebellum Using Recombinant Rabies Virus. Dohaku R, et al. Front Neural Circuits, 2019. PMID 31068795, Free PMC Article

See all (23) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Clone Names

  • MGC112357

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables fructose-bisphosphate aldolase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables fructose-bisphosphate aldolase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in fructose 1,6-bisphosphate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in glycolytic process IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within glycolytic process IEA
Inferred from Electronic Annotation
more info
  
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
fructose-bisphosphate aldolase C-A
Names
aldolase c, fructose-bisphosphate, like
zebrin II
NP_001025123.1
XP_009289839.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029952.1 → NP_001025123.1  fructose-bisphosphate aldolase C-A

    See identical proteins and their annotated locations for NP_001025123.1

    Status: PROVISIONAL

    Source sequence(s)
    BC098624
    UniProtKB/Swiss-Prot
    Q4KMC8
    Related
    ENSDARP00000074827.5, ENSDART00000080377.7
    Conserved Domains (1) summary
    pfam00274
    Location:15 → 364
    Glycolytic; Fructose-bisphosphate aldolase class-I

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    16079586..16098156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009291564.3 → XP_009289839.1  fructose-bisphosphate aldolase C-A isoform X1

    UniProtKB/TrEMBL
    A0A8M3AIE2, F1QC70
    Conserved Domains (1) summary
    pfam00274
    Location:15 → 364
    Glycolytic; Fructose-bisphosphate aldolase class-I

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394942.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    87715..103731 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4KMC8.1 GenPept UniProtKB/Swiss-Prot:Q4KMC8

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