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Hdac9 histone deacetylase 9 [ Mus musculus (house mouse) ]

Gene ID: 79221, updated on 21-Apr-2024

Summary

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Official Symbol
Hdac9provided by MGI
Official Full Name
histone deacetylase 9provided by MGI
Primary source
MGI:MGI:1931221
See related
Ensembl:ENSMUSG00000004698 AllianceGenome:MGI:1931221
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
HD9; HD7B; HDRP; Mitr; Hdac7b; mKIAA0744; D030072B18Rik
Summary
Enables DNA-binding transcription factor binding activity and transcription corepressor activity. Acts upstream of or within several processes, including determination of adult lifespan; negative regulation of transcription by RNA polymerase II; and regulation of skeletal muscle fiber development. Part of histone methyltransferase complex. Is expressed in several structures, including 2-cell stage embryo; future midbrain; heart; nervous system; and trunk myotome. Orthologous to human HDAC9 (histone deacetylase 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in frontal lobe adult (RPKM 2.7), cortex adult (RPKM 1.4) and 21 other tissues See more
Orthologs
human all
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Genomic context

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Location:
12 A3; 12 15.06 cM
Exon count:
43
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (34097579..34967094, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (34047580..34917095, complement)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40383 Neighboring gene STARR-seq mESC enhancer starr_31899 Neighboring gene Fer3 like bHLH transcription factor Neighboring gene twist basic helix-loop-helix transcription factor 1 Neighboring gene STARR-seq mESC enhancer starr_31900 Neighboring gene predicted gene, 40384 Neighboring gene predicted gene, 51984 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E8481 Neighboring gene predicted gene, 40875 Neighboring gene predicted gene, 24429 Neighboring gene predicted gene, 33864 Neighboring gene phosphoribosyl pyrophosphate synthetase 1-like 1 Neighboring gene predicted gene, 40385

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. HDAC9-mediated epithelial cell cycle arrest in G2/M contributes to kidney fibrosis in male mice. Zhang Y, et al. Nat Commun, 2023 May 25. PMID 37230975, Free PMC Article
  2. Histone deacetylase 9 promotes endothelial-mesenchymal transition and an unfavorable atherosclerotic plaque phenotype. Lecce L, et al. J Clin Invest, 2021 Aug 2. PMID 34338228, Free PMC Article
  3. Histone deacetylase 9 deficiency exaggerates uterine M2 macrophage polarization. Liu Y, et al. J Cell Mol Med, 2021 Aug. PMID 34145738, Free PMC Article
  4. Impaired autophagy triggered by HDAC9 in mesenchymal stem cells accelerates bone mass loss. Zhang L, et al. Stem Cell Res Ther, 2020 Jul 3. PMID 32620134, Free PMC Article
  5. HDAC9 deficiency promotes tumor progression by decreasing the CD8(+) dendritic cell infiltration of the tumor microenvironment. Ning Y, et al. J Immunother Cancer, 2020 Jun. PMID 32554611, Free PMC Article

See all (94) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. CircHDAC9 regulates myocardial ischemia-reperfusion injury via miR-671-5p/SOX4 signaling axis.
    Title: CircHDAC9 regulates myocardial ischemia-reperfusion injury via miR-671-5p/SOX4 signaling axis.
  2. Identification of HDAC9 and ARRDC4 as potential biomarkers and targets for treatment of type 2 diabetes.
    Title: Identification of HDAC9 and ARRDC4 as potential biomarkers and targets for treatment of type 2 diabetes.
  3. Histone deacetylase 9-mediated phenotypic transformation of vascular smooth muscle cells is a potential target for treating aortic aneurysm/dissection.
    Title: Histone deacetylase 9-mediated phenotypic transformation of vascular smooth muscle cells is a potential target for treating aortic aneurysm/dissection.
  4. Endothelial beta-catenin upregulation and Y142 phosphorylation drive diabetic angiogenesis via upregulating KDR/HDAC9.
    Title: Endothelial β-catenin upregulation and Y142 phosphorylation drive diabetic angiogenesis via upregulating KDR/HDAC9.
  5. HDAC9-mediated calmodulin deacetylation induces memory impairment in Alzheimer's disease.
    Title: HDAC9-mediated calmodulin deacetylation induces memory impairment in Alzheimer's disease.
  6. HDAC9 inhibition reduces skeletal muscle atrophy and enhances regeneration in mice with cigarette smoke-induced COPD.
    Title: HDAC9 inhibition reduces skeletal muscle atrophy and enhances regeneration in mice with cigarette smoke-induced COPD.
  7. Impact of housing temperature on adipose tissue HDAC9 expression and adipogenic differentiation in high fat-fed mice.
    Title: Impact of housing temperature on adipose tissue HDAC9 expression and adipogenic differentiation in high fat-fed mice.
  8. Molecular mechanism and therapeutic potential of HDAC9 in intervertebral disc degeneration.
    Title: Molecular mechanism and therapeutic potential of HDAC9 in intervertebral disc degeneration.
  9. Histone deacetylase 9 exacerbates podocyte injury in hyperhomocysteinemia through epigenetic repression of Klotho.
    Title: Histone deacetylase 9 exacerbates podocyte injury in hyperhomocysteinemia through epigenetic repression of Klotho.
  10. Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
    Title: Upregulation of HDAC9 in hippocampal neurons mediates depression-like behaviours by inhibiting ANXA2 degradation.
Submit: New GeneRIF Correction See all GeneRIFs (47)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
  
enables DNA-binding transcription factor binding TAS
Traceable Author Statement
more info
 PubMed 
enables RNA polymerase II-specific DNA-binding transcription factor binding ISO
Inferred from Sequence Orthology
more info
  
enables histone H3K14 deacetylase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables histone H3K9 deacetylase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables histone H4K16 deacetylase activity ISO
Inferred from Sequence Orthology
more info
  
NOT enables histone deacetylase activity TAS
Traceable Author Statement
more info
 PubMed 
enables histone deacetylase activity TAS
Traceable Author Statement
more info
 PubMed 
enables histone deacetylase binding ISO
Inferred from Sequence Orthology
more info
  
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein kinase C binding ISO
Inferred from Sequence Orthology
more info
  
enables protein lysine deacetylase activity ISO
Inferred from Sequence Orthology
more info
  
enables transcription corepressor activity IDA
Inferred from Direct Assay
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell activation TAS
Traceable Author Statement
more info
 PubMed 
involved_in B cell differentiation TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within DNA repair IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in cellular response to insulin stimulus ISO
Inferred from Sequence Orthology
more info
  
involved_in cholesterol homeostasis ISO
Inferred from Sequence Orthology
more info
  
involved_in chromatin organization TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within determination of adult lifespan IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within heart development IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in inflammatory response TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within negative regulation of DNA-templated transcription IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in negative regulation of DNA-templated transcription ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of DNA-templated transcription TAS
Traceable Author Statement
more info
 PubMed 
involved_in negative regulation of cytokine production ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of gene expression, epigenetic IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in negative regulation of gene expression, epigenetic ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of striated muscle tissue development TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
  
involved_in nervous system development TAS
Traceable Author Statement
more info
 PubMed 
involved_in peptidyl-lysine deacetylation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of cell migration involved in sprouting angiogenesis ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within regulation of skeletal muscle fiber development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within regulation of skeletal muscle fiber differentiation IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm TAS
Traceable Author Statement
more info
 PubMed 
part_of histone deacetylase complex TAS
Traceable Author Statement
more info
 PubMed 
part_of histone methyltransferase complex IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus TAS
Traceable Author Statement
more info
 PubMed 
part_of transcription regulator complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
histone deacetylase 9
Names
MEF2-interacting transcription repressor MITR
histone deacetylase 7B
histone deacetylase-related protein
NP_001258315.1
NP_077038.2
XP_006515324.1
XP_006515325.2
XP_006515327.1
XP_006515329.1
XP_006515334.1
XP_006515336.3
XP_006515338.2
XP_006515339.2
XP_011242213.1
XP_011242214.1
XP_011242215.1
XP_011242218.1
XP_011242220.1
XP_011242223.1
XP_011242224.1
XP_017170737.1
XP_017170738.1
XP_017170739.1
XP_017170740.2
XP_017170741.2
XP_030102844.1
XP_030102845.1
XP_030102846.1
XP_030102847.1
XP_030102848.1
XP_030102850.1
XP_030102851.1
XP_030102852.1
XP_036013562.1
XP_036013563.1
XP_036013564.1
XP_036013565.1
XP_036013566.1
XP_036013567.1
XP_036013568.1
XP_036013569.1
XP_036013570.1
XP_036013571.1
XP_036013572.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001271386.1 → NP_001258315.1  histone deacetylase 9 isoform 1

    See identical proteins and their annotated locations for NP_001258315.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC113481, AC163669, AK133334, CR974575
    UniProtKB/TrEMBL
    A0A1B0GT67
    Related
    ENSMUSP00000148224.2, ENSMUST00000211752.2
    Conserved Domains (2) summary
    cd10163
    Location:59 → 148
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:653 → 1030
    HDAC_classIIa; Histone deacetylases, class IIa

  2. NM_024124.3 → NP_077038.2  histone deacetylase 9 isoform 2

    See identical proteins and their annotated locations for NP_077038.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the UTRs and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus and a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    BC098187, EL604734
    Consensus CDS
    CCDS36432.1
    UniProtKB/Swiss-Prot
    Q4QQN7, Q8R4Y6, Q99N13, Q9EPT2
    UniProtKB/TrEMBL
    A0A0R4J1F3
    Related
    ENSMUSP00000106443.3, ENSMUST00000110819.4
    Conserved Domains (1) summary
    cl23765
    Location:38 → 124
    iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    34097579..34967094 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006515264.4 → XP_006515327.1  histone deacetylase 9 isoform X7

    See identical proteins and their annotated locations for XP_006515327.1

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:59 → 148
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:653 → 1030
    HDAC_classIIa; Histone deacetylases, class IIa

  2. XM_030246984.2 → XP_030102844.1  histone deacetylase 9 isoform X7

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:59 → 148
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:653 → 1030
    HDAC_classIIa; Histone deacetylases, class IIa

  3. XM_006515266.1 → XP_006515329.1  histone deacetylase 9 isoform X7

    See identical proteins and their annotated locations for XP_006515329.1

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:59 → 148
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:653 → 1030
    HDAC_classIIa; Histone deacetylases, class IIa

  4. XM_036157671.1 → XP_036013564.1  histone deacetylase 9 isoform X7

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:59 → 148
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:653 → 1030
    HDAC_classIIa; Histone deacetylases, class IIa

  5. XM_036157672.1 → XP_036013565.1  histone deacetylase 9 isoform X7

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:59 → 148
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:653 → 1030
    HDAC_classIIa; Histone deacetylases, class IIa

  6. XM_036157670.1 → XP_036013563.1  histone deacetylase 9 isoform X7

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:59 → 148
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:653 → 1030
    HDAC_classIIa; Histone deacetylases, class IIa

  7. XM_017315249.2 → XP_017170738.1  histone deacetylase 9 isoform X11

    UniProtKB/TrEMBL
    A0A1B0GSQ5, A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:632 → 1009
    HDAC_classIIa; Histone deacetylases, class IIa

  8. XM_030246985.2 → XP_030102845.1  histone deacetylase 9 isoform X9

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:57 → 143
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:648 → 1025
    HDAC_classIIa; Histone deacetylases, class IIa

  9. XM_017315250.3 → XP_017170739.1  histone deacetylase 9 isoform X8

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:57 → 146
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:651 → 1028
    HDAC_classIIa; Histone deacetylases, class IIa

  10. XM_006515261.4 → XP_006515324.1  histone deacetylase 9 isoform X6

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:71 → 160
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:665 → 1042
    HDAC_classIIa; Histone deacetylases, class IIa

  11. XM_011243911.3 → XP_011242213.1  histone deacetylase 9 isoform X11

    See identical proteins and their annotated locations for XP_011242213.1

    UniProtKB/TrEMBL
    A0A1B0GSQ5, A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:632 → 1009
    HDAC_classIIa; Histone deacetylases, class IIa

  12. XM_017315248.2 → XP_017170737.1  histone deacetylase 9 isoform X5

    UniProtKB/TrEMBL
    A0A1B0GSE4
    Conserved Domains (2) summary
    cd10163
    Location:38 → 124
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:585 → 962
    HDAC_classIIa; Histone deacetylases, class IIa

  13. XM_011243912.2 → XP_011242214.1  histone deacetylase 9 isoform X2

    See identical proteins and their annotated locations for XP_011242214.1

    UniProtKB/TrEMBL
    A0A1B0GRH0, A0A1B0GSE4
    Related
    ENSMUSP00000147519.2, ENSMUST00000209902.2
    Conserved Domains (2) summary
    cd10163
    Location:38 → 124
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:629 → 1006
    HDAC_classIIa; Histone deacetylases, class IIa

  14. XM_036157669.1 → XP_036013562.1  histone deacetylase 9 isoform X4

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:586 → 963
    HDAC_classIIa; Histone deacetylases, class IIa

  15. XM_006515262.3 → XP_006515325.2  histone deacetylase 9 isoform X1

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:630 → 1007
    HDAC_classIIa; Histone deacetylases, class IIa

  16. XM_011243913.2 → XP_011242215.1  histone deacetylase 9 isoform X3

    UniProtKB/TrEMBL
    A0A1B0GR65, A0A1B0GT67
    Related
    ENSMUSP00000147395.2, ENSMUST00000209990.2
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:588 → 965
    HDAC_classIIa; Histone deacetylases, class IIa

  17. XM_011243916.2 → XP_011242218.1  histone deacetylase 9 isoform X10

    UniProtKB/TrEMBL
    A0A1B0GSE4
    Related
    ENSMUSP00000147903.2, ENSMUST00000210724.2
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:545 → 922
    HDAC_classIIa; Histone deacetylases, class IIa

  18. XM_011243922.4 → XP_011242224.1  histone deacetylase 9 isoform X14

    Conserved Domains (1) summary
    cd11681
    Location:598 → 975
    HDAC_classIIa; Histone deacetylases, class IIa

  19. XM_006515271.4 → XP_006515334.1  histone deacetylase 9 isoform X2

    See identical proteins and their annotated locations for XP_006515334.1

    UniProtKB/TrEMBL
    A0A1B0GRH0, A0A1B0GSE4
    Conserved Domains (2) summary
    cd10163
    Location:38 → 124
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:629 → 1006
    HDAC_classIIa; Histone deacetylases, class IIa

  20. XM_030246986.2 → XP_030102846.1  histone deacetylase 9 isoform X11

    UniProtKB/TrEMBL
    A0A1B0GSQ5, A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:632 → 1009
    HDAC_classIIa; Histone deacetylases, class IIa

  21. XM_011243921.2 → XP_011242223.1  histone deacetylase 9 isoform X13

    Conserved Domains (1) summary
    cd11681
    Location:622 → 999
    HDAC_classIIa; Histone deacetylases, class IIa

  22. XM_011243918.4 → XP_011242220.1  histone deacetylase 9 isoform X11

    See identical proteins and their annotated locations for XP_011242220.1

    UniProtKB/TrEMBL
    A0A1B0GSQ5, A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:632 → 1009
    HDAC_classIIa; Histone deacetylases, class IIa

  23. XM_030246992.2 → XP_030102852.1  histone deacetylase 9 isoform X15

    Conserved Domains (1) summary
    cd11681
    Location:314 → 691
    HDAC_classIIa; Histone deacetylases, class IIa

  24. XM_030246991.2 → XP_030102851.1  histone deacetylase 9 isoform X15

    Conserved Domains (1) summary
    cd11681
    Location:314 → 691
    HDAC_classIIa; Histone deacetylases, class IIa

  25. XM_036157678.1 → XP_036013571.1  histone deacetylase 9 isoform X15

    Conserved Domains (1) summary
    cd11681
    Location:314 → 691
    HDAC_classIIa; Histone deacetylases, class IIa

  26. XM_030246990.2 → XP_030102850.1  histone deacetylase 9 isoform X15

    Conserved Domains (1) summary
    cd11681
    Location:314 → 691
    HDAC_classIIa; Histone deacetylases, class IIa

  27. XM_036157676.1 → XP_036013569.1  histone deacetylase 9 isoform X12

    UniProtKB/TrEMBL
    A0A1B0GSE4
    Conserved Domains (2) summary
    cd10163
    Location:38 → 124
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:627 → 1004
    HDAC_classIIa; Histone deacetylases, class IIa

  28. XM_030246987.2 → XP_030102847.1  histone deacetylase 9 isoform X2

    UniProtKB/TrEMBL
    A0A1B0GRH0, A0A1B0GSE4
    Conserved Domains (2) summary
    cd10163
    Location:38 → 124
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:629 → 1006
    HDAC_classIIa; Histone deacetylases, class IIa

  29. XM_036157677.1 → XP_036013570.1  histone deacetylase 9 isoform X4

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:586 → 963
    HDAC_classIIa; Histone deacetylases, class IIa

  30. XM_030246988.2 → XP_030102848.1  histone deacetylase 9 isoform X3

    UniProtKB/TrEMBL
    A0A1B0GR65, A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:588 → 965
    HDAC_classIIa; Histone deacetylases, class IIa

  31. XM_036157675.1 → XP_036013568.1  histone deacetylase 9 isoform X11

    UniProtKB/TrEMBL
    A0A1B0GSQ5, A0A1B0GT67
    Related
    ENSMUSP00000148029.2, ENSMUST00000209750.2
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:632 → 1009
    HDAC_classIIa; Histone deacetylases, class IIa

  32. XM_036157674.1 → XP_036013567.1  histone deacetylase 9 isoform X11

    UniProtKB/TrEMBL
    A0A1B0GSQ5, A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:632 → 1009
    HDAC_classIIa; Histone deacetylases, class IIa

  33. XM_017315252.3 → XP_017170741.2  histone deacetylase 9 isoform X1

    UniProtKB/TrEMBL
    A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:630 → 1007
    HDAC_classIIa; Histone deacetylases, class IIa

  34. XM_036157673.1 → XP_036013566.1  histone deacetylase 9 isoform X11

    UniProtKB/TrEMBL
    A0A1B0GSQ5, A0A1B0GT67
    Conserved Domains (2) summary
    cd10163
    Location:38 → 127
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
    cd11681
    Location:632 → 1009
    HDAC_classIIa; Histone deacetylases, class IIa

  35. XM_017315251.2 → XP_017170740.2  histone deacetylase 9 isoform X20

    UniProtKB/TrEMBL
    A0A668KL98
    Conserved Domains (1) summary
    cd10163
    Location:59 → 148
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase

  36. XM_006515275.5 → XP_006515338.2  histone deacetylase 9 isoform X19

    UniProtKB/TrEMBL
    A0A668KL98
    Related
    ENSMUSP00000159253.2, ENSMUST00000239321.2
    Conserved Domains (1) summary
    cd10163
    Location:59 → 148
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase

  37. XM_006515273.3 → XP_006515336.3  histone deacetylase 9 isoform X18

    UniProtKB/Swiss-Prot
    Q4QQN7, Q8R4Y6, Q99N13, Q9EPT2
    Conserved Domains (1) summary
    cl25407
    Location:57 → 143
    ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)

  38. XM_006515276.2 → XP_006515339.2  histone deacetylase 9 isoform X16

    UniProtKB/TrEMBL
    A0A1B0GS15
    Related
    ENSMUSP00000159264.2, ENSMUST00000239340.2
    Conserved Domains (1) summary
    cl25407
    Location:38 → 124
    ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)

  39. XM_036157679.1 → XP_036013572.1  histone deacetylase 9 isoform X17

    UniProtKB/Swiss-Prot
    Q4QQN7, Q8R4Y6, Q99N13, Q9EPT2
    Conserved Domains (1) summary
    cd10163
    Location:86 → 175
    ClassIIa_HDAC9_Gln-rich-N; Glutamine-rich N-terminal helical domain of HDAC9, a Class IIa histone deacetylase
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q99N13.2 GenPept UniProtKB/Swiss-Prot:Q99N13

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