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trnau1apb tRNA selenocysteine 1 associated protein 1b [ Danio rerio (zebrafish) ]

Gene ID: 791478, updated on 27-Mar-2024

Summary

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Official Symbol
trnau1apbprovided by ZNC
Official Full Name
tRNA selenocysteine 1 associated protein 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2386
See related
Ensembl:ENSDARG00000056475 AllianceGenome:ZFIN:ZDB-GENE-040426-2386
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
secpl; secp43; trspap1; trnau1ap; trnau1apl; zgc:77884; wu:fa56b07; wu:fc12c07; wu:fc69f09; zgc:113964
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splice site selection. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol. Orthologous to human TRNAU1AP (tRNA selenocysteine 1 associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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Location:
chromosome: 2
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (24310635..24317249, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (24654984..24661600, complement)

Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene myosin heavy chain 7-like Neighboring gene fat storage inducing transmembrane protein 1, like Neighboring gene mitochondrial ribosomal protein L34 Neighboring gene anoctamin 8a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish (Danio rerio) vary by strain and sex in their behavioral and transcriptional responses to selenium supplementation. Benner MJ, et al. Comp Biochem Physiol A Mol Integr Physiol, 2010 Dec. PMID 20659579, Free PMC Article
  2. Roles of selenoprotein antioxidant protection in zebrafish, Danio rerio, subjected to dietary oxidative stress. Betancor MB, et al. Fish Physiol Biochem, 2015 Jun. PMID 25750091
  3. Sex-specific transcriptional responses of the zebrafish (Danio rerio) brain selenoproteome to acute sodium selenite supplementation. Benner MJ, et al. Physiol Genomics, 2013 Aug 1. PMID 23737534, Free PMC Article
  4. Dietary Seleno-l-Methionine Causes Alterations in Neurotransmitters, Ultrastructure of the Brain, and Behaviors in Zebrafish (Danio rerio). Li X, et al. Environ Sci Technol, 2021 Sep 7. PMID 34488355
  5. Selenium prevents downregulation of antioxidant selenoprotein genes by methylmercury. Penglase S, et al. Free Radic Biol Med, 2014 Oct. PMID 25064324

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC77884, MGC113964

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in mRNA splice site recognition IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
tRNA selenocysteine 1-associated protein 1-like
Names
tRNA selenocysteine 1 associated protein 1, like
tRNA selenocysteine 1-associated protein 1
tRNA selenocysteine associated protein 1, like
tRNA selenocysteine-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029966.2 → NP_001025137.2  tRNA selenocysteine 1-associated protein 1-like

    Status: VALIDATED

    Source sequence(s)
    AI601817, BQ450001, CB356560, CV489023, CV489035, EB769378
    UniProtKB/Swiss-Prot
    Q4KM14
    UniProtKB/TrEMBL
    A0A8M1N7C7, F1QXG2
    Related
    ENSDARP00000073432.3, ENSDART00000078975.4
    Conserved Domains (2) summary
    cd12610
    Location:7 → 90
    RRM1_SECp43; RNA recognition motif 1 in tRNA selenocysteine-associated protein 1 (SECp43)
    cd12612
    Location:98 → 179
    RRM2_SECp43; RNA recognition motif 2 in tRNA selenocysteine-associated protein 1 (SECp43)

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007113.7 Reference GRCz11 Primary Assembly

    Range
    24310635..24317249 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481362.1 → XP_021337037.1  tRNA selenocysteine 1-associated protein 1-like isoform X1

    UniProtKB/TrEMBL
    A0A8M9Q082
    Conserved Domains (2) summary
    cd12610
    Location:7 → 90
    RRM1_SECp43; RNA recognition motif 1 in tRNA selenocysteine-associated protein 1 (SECp43)
    cd12612
    Location:98 → 179
    RRM2_SECp43; RNA recognition motif 2 in tRNA selenocysteine-associated protein 1 (SECp43)

RNA

  1. XR_002459978.1 RNA Sequence

    Related
    ENSDART00000146170.3

  2. XR_001800920.2 RNA Sequence

    Related
    ENSDART00000137891.3

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_213251.1: Suppressed sequence

    Description
    NM_213251.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q4KM14.1 GenPept UniProtKB/Swiss-Prot:Q4KM14

Gene LinkOut

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