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JAG2 jagged canonical Notch ligand 2 [ Gallus gallus (chicken) ]

Gene ID: 776138, updated on 3-Apr-2024

Summary

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Symbol
JAG2provided by CGNC
Full Name
jagged canonical Notch ligand 2provided by CGNC
Primary source
CGNC:57670
See related
Ensembl:ENSGALG00010019830
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
27
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (51624172..51685871, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (51602983..51664650, complement)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 132 Neighboring gene uncharacterized LOC101751553 Neighboring gene uncharacterized LOC107053564 Neighboring gene uncharacterized LOC121110890 Neighboring gene nudix hydrolase 14 Neighboring gene uncharacterized LOC107053566 Neighboring gene uncharacterized LOC101751737

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation of a novel chick homolog of Serrate and its coexpression with C-Notch-1 in chick development. Hayashi H, et al. Int J Dev Biol, 1996 Dec. PMID 9032014
  2. Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis. Esteves de Lima J, et al. Elife, 2016 Aug 24. PMID 27554485, Free PMC Article
  3. A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Myat A, et al. Dev Biol, 1996 Mar 15. PMID 8631496
  4. Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation. Laufer E, et al. Nature, 1997 Mar 27. PMID 9121552
  5. Splenic gene expression profiling in White Leghorn layer inoculated with the Salmonella enterica serovar Enteritidis. Wu G, et al. Anim Genet, 2015 Dec. PMID 26358731

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Notch binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell communication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment or maintenance of epithelial cell apical/basal polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of protein-containing complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein jagged-2
Names
C-Serrate-2
jagged 2
notch ligand
serrate-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    51624172..51685871 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004936419.4 → XP_004936476.2  protein jagged-2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZBK3, O42347
    Related
    ENSGALP00010028303.1, ENSGALT00010047897.1
    Conserved Domains (3) summary
    smart00051
    Location:236 → 298
    DSL; delta serrate ligand
    smart00215
    Location:896 → 966
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:481 → 516
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  2. XM_001235688.6 → XP_001235689.3  protein jagged-2 isoform X1

    UniProtKB/TrEMBL
    O42347
    Related
    ENSGALP00010028306.1, ENSGALT00010047913.1
    Conserved Domains (3) summary
    smart00051
    Location:236 → 298
    DSL; delta serrate ligand
    smart00215
    Location:934 → 1004
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:558 → 592
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  3. XM_046941952.1 → XP_046797908.1  protein jagged-2 isoform X3

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    51602983..51664650 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040672661.2 → XP_040528595.1  protein jagged-2 isoform X2

    UniProtKB/TrEMBL
    O42347
    Conserved Domains (3) summary
    smart00051
    Location:236 → 298
    DSL; delta serrate ligand
    smart00215
    Location:896 → 966
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:520 → 554
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  2. XM_040672660.2 → XP_040528594.1  protein jagged-2 isoform X1

    UniProtKB/TrEMBL
    O42347
    Conserved Domains (3) summary
    smart00051
    Location:236 → 298
    DSL; delta serrate ligand
    smart00215
    Location:934 → 1004
    VWC_out; von Willebrand factor (vWF) type C domain
    cd00054
    Location:558 → 592
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  3. XM_046918967.1 → XP_046774923.1  protein jagged-2 isoform X3

Nucleotide Protein
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