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SH2B1 SH2B adaptor protein 1 [ Gallus gallus (chicken) ]

Gene ID: 771172, updated on 5-Mar-2024

Summary

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Symbol
SH2B1provided by CGNC
Full Name
SH2B adaptor protein 1provided by CGNC
Primary source
CGNC:1286
See related
Ensembl:ENSGALG00010029297
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
SH2B2
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 19 NC_052550.1 (4594487..4614556)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 19 NC_052591.1 (4322693..4342770)

Chromosome 19 - NC_052550.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121107260 Neighboring gene uncharacterized LOC121107259 Neighboring gene uncharacterized LOC417507 Neighboring gene cut like homeobox 1 Neighboring gene uncharacterized LOC121107261 Neighboring gene PRKR interacting protein 1 (IL11 inducible) Neighboring gene ORAI calcium release-activated calcium modulator 3 Neighboring gene alkB homolog 4, lysine demethylase Neighboring gene leucine rich repeats and WD repeat domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transmembrane receptor protein tyrosine kinase adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antigen receptor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH2B adapter protein 2
Names
SH2B adaptor protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052550.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4594487..4614556
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015296003.4 → XP_015151489.1  SH2B adapter protein 2

    UniProtKB/TrEMBL
    A0A8V1AHB4
    Conserved Domains (3) summary
    cd10411
    Location:448 → 544
    SH2_SH2B2; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:234 → 349
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:16 → 72
    Phe_ZIP; Phenylalanine zipper

  2. XM_015296002.4 → XP_015151488.1  SH2B adapter protein 2

    UniProtKB/TrEMBL
    A0A8V1AHB4
    Conserved Domains (3) summary
    cd10411
    Location:448 → 544
    SH2_SH2B2; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:234 → 349
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:16 → 72
    Phe_ZIP; Phenylalanine zipper

  3. XM_040650359.2 → XP_040506293.1  SH2B adapter protein 2

    UniProtKB/TrEMBL
    A0A8V1AHB4
    Related
    ENSGALP00010043542.1, ENSGALT00010070851.1
    Conserved Domains (3) summary
    cd10411
    Location:448 → 544
    SH2_SH2B2; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:234 → 349
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:16 → 72
    Phe_ZIP; Phenylalanine zipper

  4. XM_015296001.4 → XP_015151487.1  SH2B adapter protein 2

    UniProtKB/TrEMBL
    A0A8V1AHB4
    Conserved Domains (3) summary
    cd10411
    Location:448 → 544
    SH2_SH2B2; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:234 → 349
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:16 → 72
    Phe_ZIP; Phenylalanine zipper

  5. XM_040650358.2 → XP_040506292.1  SH2B adapter protein 2

    UniProtKB/TrEMBL
    A0A8V1AHB4
    Conserved Domains (3) summary
    cd10411
    Location:448 → 544
    SH2_SH2B2; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:234 → 349
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:16 → 72
    Phe_ZIP; Phenylalanine zipper

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052591.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4322693..4342770
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046930224.1 → XP_046786180.1  SH2B adapter protein 2

  2. XM_046930221.1 → XP_046786177.1  SH2B adapter protein 2

  3. XM_046930223.1 → XP_046786179.1  SH2B adapter protein 2

  4. XM_046930220.1 → XP_046786176.1  SH2B adapter protein 2

  5. XM_046930222.1 → XP_046786178.1  SH2B adapter protein 2

Nucleotide Protein
Heading Accession and Version

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