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PDE4C phosphodiesterase 4C [ Pan troglodytes (chimpanzee) ]

Gene ID: 748644, updated on 3-Apr-2024

Summary

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Official Symbol
PDE4Cprovided by VGNC
Official Full Name
phosphodiesterase 4Cprovided by VGNC
Primary source
VGNC:VGNC:55598
Locus tag
CK820_G0026089
See related
Ensembl:ENSPTRG00000010699
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (20857598..20883069, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (20857637..20887205, complement)

Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene MPV17 mitochondrial inner membrane protein like 2 Neighboring gene RAB3A, member RAS oncogene family Neighboring gene colon, intestine and stomach enriched 1 Neighboring gene mucin-2-like Neighboring gene IQ motif containing N

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Keynote review: phosphodiesterase-4 as a therapeutic target. Houslay MD, et al. Drug Discov Today, 2005 Nov 15. PMID 16257373

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Keynote review: phosphodiesterase-4 as a therapeutic target
    Title: Keynote review: phosphodiesterase-4 as a therapeutic target.
Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
3',5'-cyclic-AMP phosphodiesterase 4C
Names
cAMP-specific 3',5'-cyclic phosphodiesterase 4C pseudogene
phosphodiesterase 4C, cAMP-specific

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    20857598..20883069 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054673529.2 → XP_054529504.1  3',5'-cyclic-AMP phosphodiesterase 4C isoform X1

    UniProtKB/TrEMBL
    A0A2I3RW89, A0A2J8LT97, A0A6D2X3I1

  2. XM_016935500.4 → XP_016790989.1  3',5'-cyclic-AMP phosphodiesterase 4C isoform X2

    UniProtKB/TrEMBL
    A0A2I3TRH1, A0A2J8LTD3, A0A6D2X8G2
    Related
    ENSPTRP00000091840.1
    Conserved Domains (1) summary
    pfam00233
    Location:356 → 593
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  3. XM_016935497.4 → XP_016790986.1  3',5'-cyclic-AMP phosphodiesterase 4C isoform X3

    UniProtKB/TrEMBL
    A0A2J8LTB4
    Conserved Domains (1) summary
    pfam00233
    Location:282 → 519
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase

  4. XM_063800615.1 → XP_063656685.1  3',5'-cyclic-AMP phosphodiesterase 4C isoform X3

    UniProtKB/TrEMBL
    A0A2J8LTB4

  5. XM_063800617.1 → XP_063656687.1  3',5'-cyclic-AMP phosphodiesterase 4C isoform X4

Nucleotide Protein
Heading Accession and Version

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