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ASIP agouti signaling protein [ Pan troglodytes (chimpanzee) ]

Gene ID: 747368, updated on 3-Apr-2024

Summary

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Official Symbol
ASIPprovided by VGNC
Official Full Name
agouti signaling proteinprovided by VGNC
Primary source
VGNC:VGNC:6044
Locus tag
CK820_G0043041
See related
Ensembl:ENSPTRG00000013413
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 21 NC_072419.2 (40433449..40503100)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 20 NC_072418.1 (40465193..40534845)

Chromosome 21 - NC_072419.2Genomic Context describing neighboring genes Neighboring gene small ribosomal subunit protein uS5-like Neighboring gene eukaryotic translation initiation factor 2 subunit beta Neighboring gene exportin-T-like Neighboring gene density-regulated protein-like Neighboring gene adenosylhomocysteinase Neighboring gene cell division control protein 42 homolog Neighboring gene itchy E3 ubiquitin protein ligase Neighboring gene adrenodoxin, mitochondrial-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alu-mediated 100-kb deletion in the primate genome: the loss of the agouti signaling protein gene in the lesser apes. Nakayama K, et al. Genome Res, 2006 Apr. PMID 16597585, Free PMC Article
  2. Investigation of the role of the agouti signaling protein gene (ASIP) in coat color evolution in primates. Mundy NI, et al. Mamm Genome, 2006 Dec. PMID 17143587

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables melanocortin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neuropeptide hormone activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in hormone-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in melanosome organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of melanin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
agouti-signaling protein
Names
ASP
agouti signaling protein, nonagouti homolog
agouti switch protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001135627.1 → NP_001129099.1  agouti-signaling protein precursor

    See identical proteins and their annotated locations for NP_001129099.1

    Status: PROVISIONAL

    Source sequence(s)
    EF094481
    UniProtKB/Swiss-Prot
    A1YL64, Q1XGV7
    UniProtKB/TrEMBL
    A0A2J8JYE2
    Related
    ENSPTRP00000022999.3, ENSPTRT00000024918.3
    Conserved Domains (1) summary
    smart00792
    Location:16 → 128
    Agouti; Agouti protein

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072419.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    40433449..40503100
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054674289.2 → XP_054530264.1  agouti-signaling protein isoform X1

    UniProtKB/Swiss-Prot
    A1YL64, Q1XGV7
    UniProtKB/TrEMBL
    A0A2J8JYE2

  2. XM_063802496.1 → XP_063658566.1  agouti-signaling protein isoform X1

    UniProtKB/Swiss-Prot
    A1YL64, Q1XGV7
    UniProtKB/TrEMBL
    A0A2J8JYE2
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q1XGV7.1 GenPept UniProtKB/Swiss-Prot:Q1XGV7

Gene LinkOut

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