CDK6 cyclin dependent kinase 6 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: CDK6provided by VGNC
Official Full Name: cyclin dependent kinase 6provided by VGNC
Primary source: VGNC:VGNC:13637
Locus tag: CK820_G0033039
See related: Ensembl:ENSPTRG00000019400
Gene type: protein coding
RefSeq status: MODEL
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	6	NC_072404.2 (101981684..102213458, complement)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	7	NC_072405.1 (98328981..98560616, complement)

Chromosome 6 - NC_072404.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

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General gene information

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Markers

G36999 (e-PCR)
- UniSTS:4611

G36996 (e-PCR)
- UniSTS:41995

HSC249 (e-PCR)
- UniSTS:261899

SHGC-34899 (e-PCR)
- UniSTS:49681

STS-X66365 (e-PCR)
- UniSTS:50210

G32969 (e-PCR)
- UniSTS:117546

G36998 (e-PCR)
- UniSTS:30774

RH104316 (e-PCR)
- UniSTS:98641

G37001 (e-PCR)
- UniSTS:39260

A009Y04 (e-PCR)
- UniSTS:11359

G37000 (e-PCR)
- UniSTS:5475

RH104334 (e-PCR)
- UniSTS:98659

G42163 (e-PCR)
- UniSTS:93292

RH15849 (e-PCR)
- UniSTS:6509

SHGC-33519 (e-PCR)
- UniSTS:5006

SHGC-35227 (e-PCR)
- UniSTS:49054

CDK6_2114 (e-PCR)
- UniSTS:280493

G49245 (e-PCR)
- UniSTS:109001

G49156 (e-PCR)
- UniSTS:96211

RH17944 (e-PCR)
- UniSTS:11220

RH66680 (e-PCR)
- UniSTS:7896

RH79066 (e-PCR)
- UniSTS:29413

G49183 (e-PCR)
- UniSTS:96237

HSC197 (e-PCR)
- UniSTS:255215

CDK6 (e-PCR)
- UniSTS:34801

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cyclin binding	IEA Inferred from Electronic Annotation more info	PubMed
enables cyclin-dependent protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G1/S transition of mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cell dedifferentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of G2/M transition of mitotic cell cycle	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell population proliferation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of gene expression	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to organic substance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in signal transduction	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of cyclin-dependent protein kinase holoenzyme complex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: cyclin-dependent kinase 6

XP_001167181.1

EC 2.7.11.22

XP_003318627.1

EC 2.7.11.22

XP_016813256.1

EC 2.7.11.22

XP_054511967.1

EC 2.7.11.22

XP_063670803.1

EC 2.7.11.22

XP_063670804.1

EC 2.7.11.22

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072404.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

101981684..102213458 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_003318579.6 → XP_003318627.1 cyclin-dependent kinase 6 isoform X1

See identical proteins and their annotated locations for XP_003318627.1

UniProtKB/TrEMBL

A0A2J8L443, A0A6D2W6Z6, H2QUX4

Related

ENSPTRP00000033192.5

Conserved Domains (1) summary

cd07862
Location:11 → 300

STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6
XM_063814733.1 → XP_063670803.1 cyclin-dependent kinase 6 isoform X2
XM_063814734.1 → XP_063670804.1 cyclin-dependent kinase 6 isoform X2
XM_001167181.6 → XP_001167181.1 cyclin-dependent kinase 6 isoform X1

See identical proteins and their annotated locations for XP_001167181.1

UniProtKB/TrEMBL

A0A2J8L443, A0A6D2W6Z6, H2QUX4

Conserved Domains (1) summary

cd07862
Location:11 → 300

STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6
XM_016957767.4 → XP_016813256.1 cyclin-dependent kinase 6 isoform X1

UniProtKB/TrEMBL

A0A2J8L443, A0A6D2W6Z6, H2QUX4

Conserved Domains (1) summary

cd07862
Location:11 → 300

STKc_CDK6; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 6
XM_054655992.2 → XP_054511967.1 cyclin-dependent kinase 6 isoform X3