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MMP19 matrix metallopeptidase 19 [ Pan troglodytes (chimpanzee) ]

Gene ID: 746523, updated on 29-Mar-2024

Summary

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Official Symbol
MMP19provided by VGNC
Official Full Name
matrix metallopeptidase 19provided by VGNC
Primary source
VGNC:VGNC:5481
Locus tag
CK820_G0046573
See related
Ensembl:ENSPTRG00000005066
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 10 NC_072408.2 (40168793..40175142)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 12 NC_072410.1 (38842716..38849304)

Chromosome 10 - NC_072408.2Genomic Context describing neighboring genes Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene obg-like ATPase 1 Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC746548 Neighboring gene SAP domain containing ribonucleoprotein Neighboring gene growth differentiation factor 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in collagen catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
matrix metalloproteinase-19
Names
matrix metalloproteinase 19

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072408.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    40168793..40175142
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009425177.5 → XP_009423452.1  matrix metalloproteinase-19 isoform X2

    UniProtKB/TrEMBL
    A0A2J8Q188
    Conserved Domains (3) summary
    cd00094
    Location:286 → 469
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:103 → 256
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:31 → 80
    PG_binding_1; Putative peptidoglycan binding domain

  2. XM_001154045.8 → XP_001154045.2  matrix metalloproteinase-19 isoform X1

    See identical proteins and their annotated locations for XP_001154045.2

    UniProtKB/TrEMBL
    A0A2J8Q188, A0A2J8Q192, A0A6D2XRB4, H2Q667
    Related
    ENSPTRP00000008621.4
    Conserved Domains (3) summary
    cd00094
    Location:286 → 469
    HX; Hemopexin-like repeats.; Hemopexin is a heme-binding protein that transports heme to the liver. Hemopexin-like repeats occur in vitronectin and some matrix metalloproteinases family (matrixins). The HX repeats of some matrixins bind tissue inhibitor of ...
    cd04278
    Location:103 → 256
    ZnMc_MMP; Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate ...
    pfam01471
    Location:31 → 80
    PG_binding_1; Putative peptidoglycan binding domain

  3. XM_054663224.2 → XP_054519199.1  matrix metalloproteinase-19 isoform X3

Nucleotide Protein
Heading Accession and Version

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