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PRKCH protein kinase C eta [ Pan troglodytes (chimpanzee) ]

Gene ID: 746068, updated on 29-Mar-2024

Summary

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Official Symbol
PRKCHprovided by VGNC
Official Full Name
protein kinase C etaprovided by VGNC
Primary source
VGNC:VGNC:12587
Locus tag
CK820_G0002606
See related
Ensembl:ENSPTRG00000006418
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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See PRKCH in Genome Data Viewer
Location:
chromosome: 14
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 15 NC_072413.2 (59317253..59649010)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 14 NC_072412.1 (52581920..52914028)

Chromosome 15 - NC_072413.2Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene Neighboring gene uncharacterized LOC112205384 Neighboring gene transmembrane protein 30B Neighboring gene uncharacterized LOC134808300 Neighboring gene hypoxia inducible factor 1 subunit alpha Neighboring gene small nuclear RNA activating complex polypeptide 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Major chimpanzee-specific structural changes in sperm development-associated genes. Kim RN, et al. Funct Integr Genomics, 2011 Sep. PMID 21484476

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables diacylglycerol-dependent serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein kinase C eta type
XP_001168420.1
XP_009426175.1
XP_063649010.1
XP_063649011.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072413.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    59317253..59649010
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009427900.5 → XP_009426175.1  protein kinase C eta type isoform X2

    UniProtKB/TrEMBL
    A0A2I3SYM3
    Conserved Domains (4) summary
    cd04014
    Location:8 → 140
    C2_PKC_epsilon; C2 domain in Protein Kinase C (PKC) epsilon
    pfam00069
    Location:355 → 587
    Pkinase; Protein kinase domain
    pfam00130
    Location:246 → 298
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    cl21453
    Location:359 → 610
    PKc_like; Protein Kinases, catalytic domain

  2. XM_063792940.1 → XP_063649010.1  protein kinase C eta type isoform X3

  3. XM_063792941.1 → XP_063649011.1  protein kinase C eta type isoform X4

  4. XM_001168420.7 → XP_001168420.1  protein kinase C eta type isoform X1

    See identical proteins and their annotated locations for XP_001168420.1

    UniProtKB/TrEMBL
    A0A2I3SYM3, A0A2J8PI59, A0A663DAG2, H2Q8F2
    Related
    ENSPTRP00000010886.2
    Conserved Domains (3) summary
    cd04014
    Location:8 → 140
    C2_PKC_epsilon; C2 domain in Protein Kinase C (PKC) epsilon
    cd05590
    Location:359 → 681
    STKc_nPKC_eta; Catalytic domain of the Serine/Threonine Kinase, Novel Protein Kinase C eta
    pfam00130
    Location:246 → 296
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
Nucleotide Protein
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