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PARK7 Parkinsonism associated deglycase [ Pan troglodytes (chimpanzee) ]

Gene ID: 746063, updated on 3-Apr-2024

Summary

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Official Symbol
PARK7provided by VGNC
Official Full Name
Parkinsonism associated deglycaseprovided by VGNC
Primary source
VGNC:VGNC:12952
Locus tag
CK820_G0035078
See related
Ensembl:ENSPTRG00000000102
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (224015253..224039267, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (7260415..7284044)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene ERBB receptor feedback inhibitor 1 Neighboring gene uncharacterized LOC134809420 Neighboring gene TNF receptor superfamily member 9 Neighboring gene urotensin 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables oxidoreductase activity, acting on peroxide as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glyoxal metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein deglycase DJ-1; Parkinson disease protein 7
Names
Parkinson disease (autosomal recessive, early onset) 7
parkinson protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    224015253..224039267 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001158489.8 → XP_001158489.1  Parkinson disease protein 7 isoform X1

    See identical proteins and their annotated locations for XP_001158489.1

    UniProtKB/TrEMBL
    A0A2I3SNT8, A0A2J8KXX0
    Related
    ENSPTRP00000063865.1
    Conserved Domains (2) summary
    cd03135
    Location:6 → 172
    GATase1_DJ-1; Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1
    TIGR01383
    Location:5 → 184
    not_thiJ; DJ-1 family protein

  2. XM_009447628.5 → XP_009445903.1  Parkinson disease protein 7 isoform X3

    See identical proteins and their annotated locations for XP_009445903.1

    UniProtKB/TrEMBL
    A0A2I3RGS9, H2R9I9
    Conserved Domains (2) summary
    cd03135
    Location:6 → 152
    GATase1_DJ-1; Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1
    TIGR01383
    Location:5 → 164
    not_thiJ; DJ-1 family protein

  3. XM_063805247.1 → XP_063661317.1  Parkinson disease protein 7 isoform X4

  4. XM_054662470.2 → XP_054518445.1  Parkinson disease protein 7 isoform X5

  5. XM_001158093.7 → XP_001158093.2  Parkinson disease protein 7 isoform X1

    See identical proteins and their annotated locations for XP_001158093.2

    UniProtKB/TrEMBL
    A0A2I3SNT8, A0A2J8KXX0
    Conserved Domains (2) summary
    cd03135
    Location:6 → 172
    GATase1_DJ-1; Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1
    TIGR01383
    Location:5 → 184
    not_thiJ; DJ-1 family protein

  6. XM_009447621.5 → XP_009445896.1  Parkinson disease protein 7 isoform X3

    See identical proteins and their annotated locations for XP_009445896.1

    UniProtKB/TrEMBL
    A0A2I3RGS9, H2R9I9
    Related
    ENSPTRP00000052888.3
    Conserved Domains (2) summary
    cd03135
    Location:6 → 152
    GATase1_DJ-1; Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1
    TIGR01383
    Location:5 → 164
    not_thiJ; DJ-1 family protein

  7. XM_054662468.2 → XP_054518443.1  Parkinson disease protein 7 isoform X5

  8. XM_063805245.1 → XP_063661315.1  Parkinson disease protein 7 isoform X4

  9. XM_016953465.4 → XP_016808954.1  Parkinson disease protein 7 isoform X1

    UniProtKB/TrEMBL
    A0A2I3SNT8, A0A2J8KXX0
    Related
    ENSPTRP00000078598.1
    Conserved Domains (2) summary
    cd03135
    Location:6 → 172
    GATase1_DJ-1; Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1
    TIGR01383
    Location:5 → 184
    not_thiJ; DJ-1 family protein

  10. XM_054662459.2 → XP_054518434.1  Parkinson disease protein 7 isoform X2

Nucleotide Protein
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