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NR1I2 nuclear receptor subfamily 1 group I member 2 [ Pan troglodytes (chimpanzee) ]

Gene ID: 745458, updated on 29-Mar-2024

Summary

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Official Symbol
NR1I2provided by VGNC
Official Full Name
nuclear receptor subfamily 1 group I member 2provided by VGNC
Primary source
VGNC:VGNC:7079
Locus tag
CK820_G0023887
See related
Ensembl:ENSPTRG00000015263
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 2 NC_086015.1 (123085996..123122375)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 3 NC_072401.1 (122978342..123031752)

Chromosome 2 - NC_086015.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107970735 Neighboring gene cytochrome c oxidase copper chaperone COX17 Neighboring gene cilia and flagella associated protein 91 Neighboring gene uncharacterized LOC107970736 Neighboring gene prohibitin 1-like Neighboring gene glycogen synthase kinase 3 beta Neighboring gene presenilin-associated rhomboid-like protein, mitochondrial Neighboring gene uncharacterized LOC134809471

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
nuclear receptor subfamily 1 group I member 2
Names
pregnane X receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_086015.1 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    123085996..123122375
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001164025.6 → XP_001164025.1  nuclear receptor subfamily 1 group I member 2 isoform X1

    See identical proteins and their annotated locations for XP_001164025.1

    UniProtKB/TrEMBL
    A0A2J8M3I4
    Conserved Domains (2) summary
    cd06934
    Location:88 → 373
    NR_LBD_PXR_like; The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor
    cl02596
    Location:1 → 72
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  2. XM_003309941.6 → XP_003309989.1  nuclear receptor subfamily 1 group I member 2 isoform X2

    UniProtKB/TrEMBL
    A0A2J8M3I5, A0A6D2Y2W5, H2QN59
    Related
    ENSPTRP00000026312.5
    Conserved Domains (2) summary
    cd06934
    Location:88 → 336
    NR_LBD_PXR_like; The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor
    cl02596
    Location:1 → 72
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers

  3. XM_016941719.4 → XP_016797208.1  nuclear receptor subfamily 1 group I member 2 isoform X3

    UniProtKB/TrEMBL
    A0A2I3S3V5, A0A2J8M3I0, A0A2J8M3I4, A0A6D2W550
    Related
    ENSPTRP00000071628.1
    Conserved Domains (2) summary
    cd06934
    Location:182 → 467
    NR_LBD_PXR_like; The ligand binding domain of xenobiotic receptors:pregnane X receptor and constitutive androstane receptor
    cd07162
    Location:79 → 166
    NR_DBD_PXR; DNA-binding domain of pregnane X receptor (PXRs) is composed of two C4-type zinc fingers
Nucleotide Protein
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