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DFFB DNA fragmentation factor subunit beta [ Pan troglodytes (chimpanzee) ]

Gene ID: 744932, updated on 29-Mar-2024

Summary

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Official Symbol
DFFBprovided by VGNC
Official Full Name
DNA fragmentation factor subunit betaprovided by VGNC
Primary source
VGNC:VGNC:10600
Locus tag
CK820_G0040625
See related
Ensembl:ENSPTRG00000000070
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 1 NC_072398.2 (228192629..228222076, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 1 NC_072398.1 (3077274..3106672)

Chromosome 1 - NC_072398.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104005916 Neighboring gene uncharacterized LOC107974589 Neighboring gene chromosome 1 C1orf174 homolog Neighboring gene centrosomal protein 104 Neighboring gene leucine rich repeat containing 47 Neighboring gene small integral membrane protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic DNA fragmentation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA fragmentation factor subunit beta
Names
DNA fragmentation factor, 40 kD, beta polypeptide
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072398.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    228192629..228222076 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016952850.4 → XP_016808339.1  DNA fragmentation factor subunit beta isoform X2

    UniProtKB/TrEMBL
    A0A2J8K8X0, A0A6D2XJJ8, K6ZGT0
    Related
    ENSPTRP00000064348.1
    Conserved Domains (2) summary
    cd06535
    Location:4 → 80
    CIDE_N_CAD; CIDE_N domain of CAD nuclease. The CIDE_N (cell death-inducing DFF45-like effector, N-terminal) domain is found at the N-terminus of CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are ...
    pfam09230
    Location:100 → 323
    DFF40; DNA fragmentation factor 40 kDa

  2. XM_016952877.4 → XP_016808366.1  DNA fragmentation factor subunit beta isoform X1

    UniProtKB/TrEMBL
    A0A2J8K924
    Conserved Domains (2) summary
    cd06535
    Location:4 → 80
    CIDE_N_CAD; CIDE_N domain of CAD nuclease. The CIDE_N (cell death-inducing DFF45-like effector, N-terminal) domain is found at the N-terminus of CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are ...
    pfam09230
    Location:124 → 347
    DFF40; DNA fragmentation factor 40 kDa

  3. XM_016952873.4 → XP_016808362.1  DNA fragmentation factor subunit beta isoform X3

    UniProtKB/TrEMBL
    A0A2J8K932

RNA

  1. XR_008546551.2 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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