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TLE5 TLE family member 5, transcriptional modulator [ Pan troglodytes (chimpanzee) ]

Gene ID: 744806, updated on 29-Mar-2024

Summary

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Gene symbol
TLE5
Gene description
TLE family member 5, transcriptional modulator
Locus tag
CK820_G0051196
See related
Ensembl:ENSPTRG00000010253
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan troglodytes
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
AES
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 20 NC_072418.2 (5398240..5408428, complement)
RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 19 NC_072417.1 (5398311..5408371, complement)

Chromosome 20 - NC_072418.2Genomic Context describing neighboring genes Neighboring gene TLE family member 6, subcortical maternal complex member Neighboring gene TLE family member 2, transcriptional corepressor Neighboring gene G protein subunit alpha 11 Neighboring gene uncharacterized LOC134809058

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TLE family member 5; TLE family member 5, transcriptional modulator
Names
amino-terminal enhancer of split

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

  1. NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Range
    5398240..5408428 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024351912.3 → XP_024207680.1  TLE family member 5 isoform X1

    UniProtKB/TrEMBL
    A0A2J8J2T9
    Conserved Domains (1) summary
    pfam03920
    Location:77 → 199
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  2. XM_024351913.2 → XP_024207681.1  TLE family member 5 isoform X2

    Conserved Domains (1) summary
    pfam03920
    Location:77 → 198
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  3. XM_016937028.4 → XP_016792517.1  TLE family member 5 isoform X4

    UniProtKB/TrEMBL
    A0A2I3S2S2
    Conserved Domains (1) summary
    pfam03920
    Location:11 → 131
    TLE_N; Groucho/TLE N-terminal Q-rich domain

  4. XM_016937027.4 → XP_016792516.1  TLE family member 5 isoform X3

    UniProtKB/TrEMBL
    A0A2I3S2S2, A0A2J8J2U0, A0A6D2WDT0, H2QEX9, K7CBT2
    Related
    ENSPTRP00000017421.4
    Conserved Domains (1) summary
    pfam03920
    Location:11 → 132
    TLE_N; Groucho/TLE N-terminal Q-rich domain

RNA

  1. XR_010153516.1 RNA Sequence

Nucleotide Protein
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