APOC2 apolipoprotein C2 [Pan troglodytes (chimpanzee)] - Gene

Summary

Gene symbol: APOC2
Gene description: apolipoprotein C2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 20

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	20	NC_072418.2 (47901519..47904990)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	19	NC_072417.1 (47901545..47905014)

Chromosome 20 - NC_072418.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH91449 (e-PCR)
- UniSTS:84784

RH18398 (e-PCR)
- UniSTS:57773

GDB:179875 (e-PCR)
- UniSTS:155055

RH46551 (e-PCR)
- UniSTS:31667

RH36305 (e-PCR)
- UniSTS:63673

APOC2_2725 (e-PCR)
- UniSTS:462031

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables lipid binding	IEA Inferred from Electronic Annotation more info	PubMed
enables lipoprotein lipase activator activity	IEA Inferred from Electronic Annotation more info	PubMed
enables phospholipase activator activity	IEA Inferred from Electronic Annotation more info	PubMed
enables phospholipase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in chylomicron remnant clearance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in high-density lipoprotein particle clearance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in lipid metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in lipid transport	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of very-low-density lipoprotein particle clearance	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of lipoprotein lipase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of phospholipase activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of phospholipid catabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of chylomicron	IEA Inferred from Electronic Annotation more info	PubMed
part_of intermediate-density lipoprotein particle	IEA Inferred from Electronic Annotation more info	PubMed
part_of low-density lipoprotein particle	IEA Inferred from Electronic Annotation more info	PubMed
part_of spherical high-density lipoprotein particle	IEA Inferred from Electronic Annotation more info	PubMed
part_of very-low-density lipoprotein particle	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: apolipoprotein C-II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243899.1 → NP_001230828.1 apolipoprotein C-II precursor

See identical proteins and their annotated locations for NP_001230828.1

Status: VALIDATED

Source sequence(s)

JAQQLN020000020

UniProtKB/TrEMBL

H2R605

Conserved Domains (1) summary

pfam05355
Location:24 → 100

Apo-CII; Apolipoprotein C-II

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072418.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

47901519..47904990

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_024351113.3 → XP_024206881.1 apolipoprotein C-II isoform X1

Conserved Domains (1) summary

pfam05355
Location:24 → 100

Apo-CII; Apolipoprotein C-II
XM_024351114.3 → XP_024206882.1 apolipoprotein C-II isoform X1

Conserved Domains (1) summary

pfam05355
Location:24 → 100

Apo-CII; Apolipoprotein C-II